Click here to switch to the map view.

The map label for this gene is motA [H]

Identifier: 237814249

GI number: 237814249

Start: 3877436

End: 3878296

Strand: Reverse

Name: motA [H]

Synonym: GBP346_A4044

Alternate gene names: 237814249

Gene position: 3878296-3877436 (Counterclockwise)

Preceding gene: 237814250

Following gene: 237814248

Centisome position: 94.63

GC content: 65.39

Gene sequence:

>861_bases
GTGCTGATTTTCGTGGGAACTCTCGTGACCTTGTTGTCCGTGTTCGGCGGCTACGCGCTGGCGGGCGGGCACCTGGGCGC
GCTCGTGCAACCCGTCGAGATCCTGATGATCGTCGGCGCGGGCGTCGGCGCGTTCATCATCGGCAACGGCATCAAGACGA
TCAAGGCGACGCTGCGCGTGCTGCCCACGCTGTTCAAGGGCTCGAAGTACAACAAGGACATCTACATGGAGCTGATGGCG
CTCCTGTACGTGTTGCTCGCGAAGGCGCGCAAGGAAGGCACGCTCACGCTCGAGGCGGACATCGACGATCCCGAGAAGAG
CCCGATCTTCACCCAGTATCCGAAGATCCTCGCCGACCATCACATCGTCGAATTCCTGACCGACTACCTGCGCCTGATGG
TGGGCGGCAACATGAACGCGTTCGAGATCGAAAGCCTGATGGACGAGGAGATCGAGACGCACCACGCGGAAGGCGAAGGC
CCCGCGCACGCGCTGATGCGCGTCGGCGACGCGATGCCGGCGTTCGGGATCGTCGCCGCGGTGATGGGCGTCGTCCACAC
GATGGCCTCCGCCGACAAGCCGCCCGCGGTGCTGGGCGCGATGATCGCGCAGGCGCTCGTCGGCACGTTCCTCGGCATTC
TGCTGTCGTACGGCCTGATCGGCCCGCTCGCGAGCCTCGCGGAGCAGCGCGTGGCCGAGTCGACCAAGATGTTCCAGTGC
ATCAAGGTGACGATCCTCGCGAGCCTGAACGGCTATGCGCCCGCGATCGCCGTCGAGTTCGGCCGCAAGGTGCTGTTCTC
GACCGAGCGTCCGTCGTTCGCCGAGCTCGAGGAGCACGTGCGCCGCGTGAAGGCGAAGTGA

Upstream 100 bases:

>100_bases
ACCGGCGAGCCCGCGCGAGGCGTTTCCCAAAGTTTTCGTTACGACTGCCGTAAACCACTTAACGGCGGCCTCCCGGCTGC
TCATTCGTGAGGGACAGGCA

Downstream 100 bases:

>100_bases
GCGCGAGGGCACGGACATGAGCAAGGGCAAGGATCAGGCGATCATCGTCAAGCGGGTGAACCAGCAGAAGAAGGGGCACC
ACGGCGGCGCATGGAAGCTC

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLIFVGTLVTLLSVFGGYALAGGHLGALVQPVEILMIVGAGVGAFIIGNGIKTIKATLRVLPTLFKGSKYNKDIYMELMA
LLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADHHIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEG
PAHALMRVGDAMPAFGIVAAVMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
IKVTILASLNGYAPAIAVEFGRKVLFSTERPSFAELEEHVRRVKAK

Sequences:

>Translated_286_residues
MLIFVGTLVTLLSVFGGYALAGGHLGALVQPVEILMIVGAGVGAFIIGNGIKTIKATLRVLPTLFKGSKYNKDIYMELMA
LLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADHHIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEG
PAHALMRVGDAMPAFGIVAAVMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
IKVTILASLNGYAPAIAVEFGRKVLFSTERPSFAELEEHVRRVKAK
>Mature_286_residues
MLIFVGTLVTLLSVFGGYALAGGHLGALVQPVEILMIVGAGVGAFIIGNGIKTIKATLRVLPTLFKGSKYNKDIYMELMA
LLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADHHIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEG
PAHALMRVGDAMPAFGIVAAVMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
IKVTILASLNGYAPAIAVEFGRKVLFSTERPSFAELEEHVRRVKAK

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=284, Percent_Identity=63.3802816901408, Blast_Score=380, Evalue=1e-107,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30727; Mature: 30727

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIFVGTLVTLLSVFGGYALAGGHLGALVQPVEILMIVGAGVGAFIIGNGIKTIKATLRV
CEEEHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHH
LPTLFKGSKYNKDIYMELMALLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADH
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
HIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEGPAHALMRVGDAMPAFGIVAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHH
VMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKVTILASLNGYAPAIAVEFGRKVLFSTERPSFAELEEHVRRVKAK
HHHHHHHHCCCCCHHHHHHHCCHHEECCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLIFVGTLVTLLSVFGGYALAGGHLGALVQPVEILMIVGAGVGAFIIGNGIKTIKATLRV
CEEEHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHH
LPTLFKGSKYNKDIYMELMALLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADH
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
HIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEGPAHALMRVGDAMPAFGIVAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHH
VMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKVTILASLNGYAPAIAVEFGRKVLFSTERPSFAELEEHVRRVKAK
HHHHHHHHCCCCCHHHHHHHCCHHEECCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]