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The map label for this gene is cheW [H]

Identifier: 237814245

GI number: 237814245

Start: 3873081

End: 3873608

Strand: Reverse

Name: cheW [H]

Synonym: GBP346_A4040

Alternate gene names: 237814245

Gene position: 3873608-3873081 (Counterclockwise)

Preceding gene: 237814246

Following gene: 237814244

Centisome position: 94.51

GC content: 63.64

Gene sequence:

>528_bases
GTGTCCGAAGTCCAAACGAATCATCCGGCCGCGCCGAACGCGGCCAGCCGCCGCGACGCCGAACAGGGCGACGCCGCGGG
CCAGGAGTTTCTCGTCTTCACGCTCGGCGACGAGGAATACGGCATCGACATTCTGAAAGTACAGGAAATCCGCGGCTACG
ACAGCGTCACGCGGATCGCGAACGCGCCCGATTTCATCAAGGGCGTGATCAACCTGCGCGGCATCATCGTGCCGATCGTC
GACATGCGGATCAAGTTCCACCTCGGCCGCGTCGAGTACGACCATCAGACGGTCGTGATCATCCTGAACGTCGCGCATCG
CGTCGTCGGGATGGTCGTCGACGGCGTGTCCGACGTGCTCACGCTGTCGACCGAGCAGATCATGCCCGCGCCGGAATTCG
GCGGCGTGCTGACGACCGAGTACCTGACGGGCCTCGGCACGGTCGACGGCCGGATGCTGATCCTGATGGACATCGAGAAG
CTGATGACGAGCAAGGAGATGGCGCTGATCGAGACGCTCGGCGCATAA

Upstream 100 bases:

>100_bases
CGCGGCGCTCAATCGCGAGACCCGCGCGGCGCACGGCGCGCATTCGAGCGCCGCGCTCGCCGCGTCCTAACTTACGTGAT
CCATCGATCAGGGGGCTAAC

Downstream 100 bases:

>100_bases
GCGGGCGCGACGCACGCAACGCAACTACGGGGAGCTGACGATGCTGCACAACTGGTCGATCCGCACGACGCTGACGGCCG
TCGGATTCATGCTGGTGCTC

Product: chemotaxis protein CheW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSEVQTNHPAAPNAASRRDAEQGDAAGQEFLVFTLGDEEYGIDILKVQEIRGYDSVTRIANAPDFIKGVINLRGIIVPIV
DMRIKFHLGRVEYDHQTVVIILNVAHRVVGMVVDGVSDVLTLSTEQIMPAPEFGGVLTTEYLTGLGTVDGRMLILMDIEK
LMTSKEMALIETLGA

Sequences:

>Translated_175_residues
MSEVQTNHPAAPNAASRRDAEQGDAAGQEFLVFTLGDEEYGIDILKVQEIRGYDSVTRIANAPDFIKGVINLRGIIVPIV
DMRIKFHLGRVEYDHQTVVIILNVAHRVVGMVVDGVSDVLTLSTEQIMPAPEFGGVLTTEYLTGLGTVDGRMLILMDIEK
LMTSKEMALIETLGA
>Mature_174_residues
SEVQTNHPAAPNAASRRDAEQGDAAGQEFLVFTLGDEEYGIDILKVQEIRGYDSVTRIANAPDFIKGVINLRGIIVPIVD
MRIKFHLGRVEYDHQTVVIILNVAHRVVGMVVDGVSDVLTLSTEQIMPAPEFGGVLTTEYLTGLGTVDGRMLILMDIEKL
MTSKEMALIETLGA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=149, Percent_Identity=71.8120805369127, Blast_Score=219, Evalue=7e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 19110; Mature: 18979

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVQTNHPAAPNAASRRDAEQGDAAGQEFLVFTLGDEEYGIDILKVQEIRGYDSVTRIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCHHHHHHC
NAPDFIKGVINLRGIIVPIVDMRIKFHLGRVEYDHQTVVIILNVAHRVVGMVVDGVSDVL
CCHHHHHHHHHHHHHEEEEEEEEEEEEECEEEECCCEEEEEEEHHHHHHHHHHHCHHHHH
TLSTEQIMPAPEFGGVLTTEYLTGLGTVDGRMLILMDIEKLMTSKEMALIETLGA
HCCHHHCCCCCCCCCEEHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEVQTNHPAAPNAASRRDAEQGDAAGQEFLVFTLGDEEYGIDILKVQEIRGYDSVTRIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCHHHHHHC
NAPDFIKGVINLRGIIVPIVDMRIKFHLGRVEYDHQTVVIILNVAHRVVGMVVDGVSDVL
CCHHHHHHHHHHHHHEEEEEEEEEEEEECEEEECCCEEEEEEEHHHHHHHHHHHCHHHHH
TLSTEQIMPAPEFGGVLTTEYLTGLGTVDGRMLILMDIEKLMTSKEMALIETLGA
HCCHHHCCCCCCCCCEEHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]