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The map label for this gene is ycbL [H]

Identifier: 237814213

GI number: 237814213

Start: 3841631

End: 3842275

Strand: Direct

Name: ycbL [H]

Synonym: GBP346_A4008

Alternate gene names: 237814213

Gene position: 3841631-3842275 (Clockwise)

Preceding gene: 237814211

Following gene: 237814214

Centisome position: 93.73

GC content: 67.91

Gene sequence:

>645_bases
ATGAAAGTCACGCTCATTCCGGTCACGCCGTTCCAGCAGAACTGCTCGCTGCTCGTTTGCGAAAAGACGGGACGCGCCGC
CGTCGTCGATCCGGGCGGCGATCTCGAACTGATCGAGCAGGAGGTCGCCCGGCAGCACGTGCAGGTCGAGAAGGTGCTGC
TCACGCACGGCCACGTCGACCATTGCGCGGGCGCGAAGCGGCTCGCCGCGCATTACGGCGTGCCGATCGAGGGGCCGCAC
GAAGACGAGCGCTTCTGGATCGAAAAGCTGCCGATGCAAAGCGAGCGCTTCGGCTTTCCGGCTGCCGAAGCGTTCGAGCC
GGACCGCTGGCTCGCCGACGGCGACACGCTCGCCTTCGGCGAGGAAACGCTCGAGGTCTATCACTGCCCTGGGCACACGC
CGGGCCACGTCGTATTCTTCAGCCGCGCGCATCGGCTCGCGATCGTCGGCGACGTGCTGTTCGCCGGTTCGATCGGCCGC
ACCGACTTCCCGCGCGGCAACCACGCGGACTTGATCCGCTCGATCCGCGAAAAGCTCTGGCCGCTCGGCGACGACGTCAC
GTTCGTGCCCGGCCACGGCCCCGTGTCGACGTTCGGCGACGAGCGCCGCACGAATCCGTTCGTCGCGGACGGGGTGGCGG
GATGA

Upstream 100 bases:

>100_bases
TGATTCTCTCTATGATCGAAACAATCGGCATTGAACCGGTGCGCGCGGCGAGCGCTTCGCGCGGCCAGTACAATCGGGGG
TTTTAGCCGCTTCCCGCGCC

Downstream 100 bases:

>100_bases
GCGCCGCGCCGACGATGCCGAGCCGCGAAATCTACGTGAGCACCGACGTCGAGGCGGACGGCCCGATCCCGGGCCCGCAC
TCGATGCTGAGCTTCGCGTC

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLELIEQEVARQHVQVEKVLLTHGHVDHCAGAKRLAAHYGVPIEGPH
EDERFWIEKLPMQSERFGFPAAEAFEPDRWLADGDTLAFGEETLEVYHCPGHTPGHVVFFSRAHRLAIVGDVLFAGSIGR
TDFPRGNHADLIRSIREKLWPLGDDVTFVPGHGPVSTFGDERRTNPFVADGVAG

Sequences:

>Translated_214_residues
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLELIEQEVARQHVQVEKVLLTHGHVDHCAGAKRLAAHYGVPIEGPH
EDERFWIEKLPMQSERFGFPAAEAFEPDRWLADGDTLAFGEETLEVYHCPGHTPGHVVFFSRAHRLAIVGDVLFAGSIGR
TDFPRGNHADLIRSIREKLWPLGDDVTFVPGHGPVSTFGDERRTNPFVADGVAG
>Mature_214_residues
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLELIEQEVARQHVQVEKVLLTHGHVDHCAGAKRLAAHYGVPIEGPH
EDERFWIEKLPMQSERFGFPAAEAFEPDRWLADGDTLAFGEETLEVYHCPGHTPGHVVFFSRAHRLAIVGDVLFAGSIGR
TDFPRGNHADLIRSIREKLWPLGDDVTFVPGHGPVSTFGDERRTNPFVADGVAG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=105, Percent_Identity=40, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1787158, Length=210, Percent_Identity=57.1428571428571, Blast_Score=261, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17538952, Length=192, Percent_Identity=30.2083333333333, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221330176, Length=209, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23547; Mature: 23547

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLELIEQEVARQHVQVEKVLLTHGHVD
CEEEEEECCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
HCAGAKRLAAHYGVPIEGPHEDERFWIEKLPMQSERFGFPAAEAFEPDRWLADGDTLAFG
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCHHCCCCCHHCCCCCCEECCCCEEEEC
EETLEVYHCPGHTPGHVVFFSRAHRLAIVGDVLFAGSIGRTDFPRGNHADLIRSIREKLW
CCEEEEEECCCCCCCEEEEEECCCEEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC
PLGDDVTFVPGHGPVSTFGDERRTNPFVADGVAG
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLELIEQEVARQHVQVEKVLLTHGHVD
CEEEEEECCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
HCAGAKRLAAHYGVPIEGPHEDERFWIEKLPMQSERFGFPAAEAFEPDRWLADGDTLAFG
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCHHCCCCCHHCCCCCCEECCCCEEEEC
EETLEVYHCPGHTPGHVVFFSRAHRLAIVGDVLFAGSIGRTDFPRGNHADLIRSIREKLW
CCEEEEEECCCCCCCEEEEEECCCEEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC
PLGDDVTFVPGHGPVSTFGDERRTNPFVADGVAG
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]