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The map label for this gene is gmhA [H]

Identifier: 237814209

GI number: 237814209

Start: 3838234

End: 3838812

Strand: Reverse

Name: gmhA [H]

Synonym: GBP346_A4004

Alternate gene names: 237814209

Gene position: 3838812-3838234 (Counterclockwise)

Preceding gene: 237814210

Following gene: 237814208

Centisome position: 93.66

GC content: 69.43

Gene sequence:

>579_bases
ATGTCAGTCGAACGTATTCAGCAACATATCCGCGACAGCGCCGCGCTCGTTCACGAAGCGCTCGAGGCGCTGTCCCTGCC
GATCGCGGCGGCCGTGGACGCGATGTTCATGGCGCTCGCGAACGGCAACAAGATCGTCGCATGCGGCGACGGCCCATCGG
CCGCGGCGGCCGAGCGGCTTGCCGCCGCGTTGATCGGCGGCTTCGAGCGCGAGCGTCCCGGCCTGCCCGGGCTCGCGCTC
GATACCGATGCGAGCCGCTCCGGCACGGGCGCCGACGGCGATCAGATCTTCGCGCAACAGGTGCGCACGCTTGGCCAGAC
GGGCGATGTGCTGCTCGTGCTCGATCCGCTCGGCGAATCGCCGCGCGTGCTGGCCGCCGTCGAGGAGGCGCGCGAGCGCG
AGATGATCGTCATCGCGCTGACGGGCAACGGCGGCGGGCGTCTCGGCGCATCGCTCGCCGACACCGATATTCAGATCTGC
GTGCCGTCCGAGCGGGCGGTGCGCATCCAGGAAGTCCATCTGCTGACCATCCACTGCCTGTGCGACGGCATCGACGCGAT
GCTGCTGGGCGAGGATTGA

Upstream 100 bases:

>100_bases
TGCGGCGACGCTCGGGCGGCGGGGGCGGAGTGCGGTAAACTCGCCGCACTCACGATGCCGCGCGACGCAGACCACGCGCG
CAGTACCCGATTAGGAATCG

Downstream 100 bases:

>100_bases
TTCGAAGGAGAGCCGTCGATGAGTAACAGCCGCGTCAGACAGACGCTAGTCAGAACCACGCTCGTGATCGGCCTGTCGGC
CGGCCTCGCCGCCACGCTGC

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MSVERIQQHIRDSAALVHEALEALSLPIAAAVDAMFMALANGNKIVACGDGPSAAAAERLAAALIGGFERERPGLPGLAL
DTDASRSGTGADGDQIFAQQVRTLGQTGDVLLVLDPLGESPRVLAAVEEAREREMIVIALTGNGGGRLGASLADTDIQIC
VPSERAVRIQEVHLLTIHCLCDGIDAMLLGED

Sequences:

>Translated_192_residues
MSVERIQQHIRDSAALVHEALEALSLPIAAAVDAMFMALANGNKIVACGDGPSAAAAERLAAALIGGFERERPGLPGLAL
DTDASRSGTGADGDQIFAQQVRTLGQTGDVLLVLDPLGESPRVLAAVEEAREREMIVIALTGNGGGRLGASLADTDIQIC
VPSERAVRIQEVHLLTIHCLCDGIDAMLLGED
>Mature_191_residues
SVERIQQHIRDSAALVHEALEALSLPIAAAVDAMFMALANGNKIVACGDGPSAAAAERLAAALIGGFERERPGLPGLALD
TDASRSGTGADGDQIFAQQVRTLGQTGDVLLVLDPLGESPRVLAAVEEAREREMIVIALTGNGGGRLGASLADTDIQICV
PSERAVRIQEVHLLTIHCLCDGIDAMLLGED

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=189, Percent_Identity=44.973544973545, Blast_Score=154, Evalue=3e-39,
Organism=Escherichia coli, GI1786416, Length=151, Percent_Identity=37.7483443708609, Blast_Score=94, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 19942; Mature: 19811

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVERIQQHIRDSAALVHEALEALSLPIAAAVDAMFMALANGNKIVACGDGPSAAAAERL
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
AAALIGGFERERPGLPGLALDTDASRSGTGADGDQIFAQQVRTLGQTGDVLLVLDPLGES
HHHHHCCHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCC
PRVLAAVEEAREREMIVIALTGNGGGRLGASLADTDIQICVPSERAVRIQEVHLLTIHCL
CHHHHHHHHHHCCCEEEEEEECCCCCCCCCEECCCCEEEEECCCCCEEEHHHHEEEEEEH
CDGIDAMLLGED
HCCCCEEEECCC
>Mature Secondary Structure 
SVERIQQHIRDSAALVHEALEALSLPIAAAVDAMFMALANGNKIVACGDGPSAAAAERL
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
AAALIGGFERERPGLPGLALDTDASRSGTGADGDQIFAQQVRTLGQTGDVLLVLDPLGES
HHHHHCCHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCC
PRVLAAVEEAREREMIVIALTGNGGGRLGASLADTDIQICVPSERAVRIQEVHLLTIHCL
CHHHHHHHHHHCCCEEEEEEECCCCCCCCCEECCCCEEEEECCCCCEEEHHHHEEEEEEH
CDGIDAMLLGED
HCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA