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The map label for this gene is secY [H]

Identifier: 237814125

GI number: 237814125

Start: 3761032

End: 3762378

Strand: Reverse

Name: secY [H]

Synonym: GBP346_A3911

Alternate gene names: 237814125

Gene position: 3762378-3761032 (Counterclockwise)

Preceding gene: 237814126

Following gene: 237814124

Centisome position: 91.8

GC content: 60.95

Gene sequence:

>1347_bases
TTGGCTAACAGCCCGAGTCTCGCAAAACCCGGTCGAAGCACGGCGAAGTTCGGCGATCTGCGCCGGCGTGCAATGTTCTT
GCTGCTGGCGCTGATCGTCTATCGCATCGGCGCGCACATCCCGGTGCCGGGCATCGACCCGGATCAGCTGGCGAAGCTGT
TCCAGAGCCAGGCGGGCGGCATCCTGGGCATGTTCAACATGTTCTCGGGTGGCGCGCTGTCGCGCTTCACGATCTTCGCG
CTGGGGATCATGCCGTACATTTCGGCGTCGATCATCATGCAACTGATGGCGATCGTGTCGCCGCAGCTCGAGGCGCTGAA
GAAGGAAGGGCAGGCCGGACAGCGGAAGATCACGCAGTACACGCGGTATTTCACCGTGGTGCTCGCGACGTTCCAGGCCT
TCGGCATCGCGGCCGCGCTGGAGAATCAGCCGGGCCTCGTGACCGATCCGGGCGCGGTGTTCCGTCTGACGACGGTCGTC
ACGCTGGTGACGGGCACGATGTTCCTGATGTGGCTCGGCGAGCAGATCACCGAGCGCGGTCTCGGCAACGGCATCTCGAT
CATCATCTTCGGCGGGATCGCAGCAGGGTTCCCGAATGCCGTCGGTGGGCTGTTCGAGCTGGTGCGCACGGGTTCGATGA
GCATCATTTCGGCGATCATCATCGTCGTTCTGATCGCCGCGGTGACTTACCTGGTCGTGTTCATCGAACGCGGTCAGCGC
AAGATCCTCGTGAACTACGCGAAGCGCCAGGTCGGCAACAAGATTTACGGCGGGCAGTCGTCCCACCTGCCGCTGAAGTT
GAACATGTCGGGCGTGATTCCGCCGATCTTCGCATCGTCGATCATCCTGTTTCCGGCGACGATCCTGAGCTGGTTCAGCT
CGGGCGAGCGCAAGGGCTGGATGTCCGACACGCTGCACAACGTCGCGGAAGCGCTGAAGCCGGGCCAGCCGGTGTATGTG
CTGCTGTACACGCTGGCAATCGTGTTTTTCTGCTTCTTCTACACCGCGCTGGTGTTCAACAGCAGGGAAACCGCAGACAA
CCTGAAGAAGAGCGGTGCATTCGTGCCGGGCATTCGTCCGGGCGACCAGACCGCGCGGTACATCGACCGGATCCTCACGC
GTCTCACGCTGGCCGGTGCGATCTACATCGTCTTCGTGTGTCTGCTGCCGGAGTTCCTGGTGCTGCGCTGGAACGTACCG
TTTTATTTTGGTGGAACGTCGCTGCTGATCATTGTCGTCGTCACGATGGACTTCATGGCGCAGGTGCAGTCGTACGTTAT
GTCGCAACAGTATGAGTCGCTGCTCAAGAAAGCCAATTTCAAGGGCGGCAACATCCCAATGCGTTAA

Upstream 100 bases:

>100_bases
CGACGAAGGGTGCGCGCGCCGCGATCGAAGCGGCCGGCGGTTCGTTTGCCGAGTGACACGCAACGCGTGCCGTCACTAGC
ATTTGCATCGGAGAAGATAC

Downstream 100 bases:

>100_bases
AAAGGACTTATGGCCAAAGACGATGTAATCCAGATGCAGGGTGAGGTGATCGAAAACCTTCCGAATGCGACCTTCCGGGT
GAAGCTGGAAAACGGCCACG

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MANSPSLAKPGRSTAKFGDLRRRAMFLLLALIVYRIGAHIPVPGIDPDQLAKLFQSQAGGILGMFNMFSGGALSRFTIFA
LGIMPYISASIIMQLMAIVSPQLEALKKEGQAGQRKITQYTRYFTVVLATFQAFGIAAALENQPGLVTDPGAVFRLTTVV
TLVTGTMFLMWLGEQITERGLGNGISIIIFGGIAAGFPNAVGGLFELVRTGSMSIISAIIIVVLIAAVTYLVVFIERGQR
KILVNYAKRQVGNKIYGGQSSHLPLKLNMSGVIPPIFASSIILFPATILSWFSSGERKGWMSDTLHNVAEALKPGQPVYV
LLYTLAIVFFCFFYTALVFNSRETADNLKKSGAFVPGIRPGDQTARYIDRILTRLTLAGAIYIVFVCLLPEFLVLRWNVP
FYFGGTSLLIIVVVTMDFMAQVQSYVMSQQYESLLKKANFKGGNIPMR

Sequences:

>Translated_448_residues
MANSPSLAKPGRSTAKFGDLRRRAMFLLLALIVYRIGAHIPVPGIDPDQLAKLFQSQAGGILGMFNMFSGGALSRFTIFA
LGIMPYISASIIMQLMAIVSPQLEALKKEGQAGQRKITQYTRYFTVVLATFQAFGIAAALENQPGLVTDPGAVFRLTTVV
TLVTGTMFLMWLGEQITERGLGNGISIIIFGGIAAGFPNAVGGLFELVRTGSMSIISAIIIVVLIAAVTYLVVFIERGQR
KILVNYAKRQVGNKIYGGQSSHLPLKLNMSGVIPPIFASSIILFPATILSWFSSGERKGWMSDTLHNVAEALKPGQPVYV
LLYTLAIVFFCFFYTALVFNSRETADNLKKSGAFVPGIRPGDQTARYIDRILTRLTLAGAIYIVFVCLLPEFLVLRWNVP
FYFGGTSLLIIVVVTMDFMAQVQSYVMSQQYESLLKKANFKGGNIPMR
>Mature_447_residues
ANSPSLAKPGRSTAKFGDLRRRAMFLLLALIVYRIGAHIPVPGIDPDQLAKLFQSQAGGILGMFNMFSGGALSRFTIFAL
GIMPYISASIIMQLMAIVSPQLEALKKEGQAGQRKITQYTRYFTVVLATFQAFGIAAALENQPGLVTDPGAVFRLTTVVT
LVTGTMFLMWLGEQITERGLGNGISIIIFGGIAAGFPNAVGGLFELVRTGSMSIISAIIIVVLIAAVTYLVVFIERGQRK
ILVNYAKRQVGNKIYGGQSSHLPLKLNMSGVIPPIFASSIILFPATILSWFSSGERKGWMSDTLHNVAEALKPGQPVYVL
LYTLAIVFFCFFYTALVFNSRETADNLKKSGAFVPGIRPGDQTARYIDRILTRLTLAGAIYIVFVCLLPEFLVLRWNVPF
YFGGTSLLIIVVVTMDFMAQVQSYVMSQQYESLLKKANFKGGNIPMR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=449, Percent_Identity=64.5879732739421, Blast_Score=531, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48976; Mature: 48845

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSPSLAKPGRSTAKFGDLRRRAMFLLLALIVYRIGAHIPVPGIDPDQLAKLFQSQAGG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCC
ILGMFNMFSGGALSRFTIFALGIMPYISASIIMQLMAIVSPQLEALKKEGQAGQRKITQY
CEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHH
TRYFTVVLATFQAFGIAAALENQPGLVTDPGAVFRLTTVVTLVTGTMFLMWLGEQITERG
HHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LGNGISIIIFGGIAAGFPNAVGGLFELVRTGSMSIISAIIIVVLIAAVTYLVVFIERGQR
CCCCCEEEEECCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KILVNYAKRQVGNKIYGGQSSHLPLKLNMSGVIPPIFASSIILFPATILSWFSSGERKGW
HHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
MSDTLHNVAEALKPGQPVYVLLYTLAIVFFCFFYTALVFNSRETADNLKKSGAFVPGIRP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
GDQTARYIDRILTRLTLAGAIYIVFVCLLPEFLVLRWNVPFYFGGTSLLIIVVVTMDFMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHH
QVQSYVMSQQYESLLKKANFKGGNIPMR
HHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ANSPSLAKPGRSTAKFGDLRRRAMFLLLALIVYRIGAHIPVPGIDPDQLAKLFQSQAGG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCC
ILGMFNMFSGGALSRFTIFALGIMPYISASIIMQLMAIVSPQLEALKKEGQAGQRKITQY
CEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHH
TRYFTVVLATFQAFGIAAALENQPGLVTDPGAVFRLTTVVTLVTGTMFLMWLGEQITERG
HHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LGNGISIIIFGGIAAGFPNAVGGLFELVRTGSMSIISAIIIVVLIAAVTYLVVFIERGQR
CCCCCEEEEECCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KILVNYAKRQVGNKIYGGQSSHLPLKLNMSGVIPPIFASSIILFPATILSWFSSGERKGW
HHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
MSDTLHNVAEALKPGQPVYVLLYTLAIVFFCFFYTALVFNSRETADNLKKSGAFVPGIRP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
GDQTARYIDRILTRLTLAGAIYIVFVCLLPEFLVLRWNVPFYFGGTSLLIIVVVTMDFMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHH
QVQSYVMSQQYESLLKKANFKGGNIPMR
HHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9322765; 10952301 [H]