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The map label for this gene is hisC_2 [H]

Identifier: 237814065

GI number: 237814065

Start: 3701394

End: 3702464

Strand: Reverse

Name: hisC_2 [H]

Synonym: GBP346_A3850

Alternate gene names: 237814065

Gene position: 3702464-3701394 (Counterclockwise)

Preceding gene: 237814066

Following gene: 237814064

Centisome position: 90.34

GC content: 69.37

Gene sequence:

>1071_bases
ATGACTACGCCAGAAGACATCATCCGCCGCGACGTGCTCGCGATGACGGGCTACCCGGTGCCGGACGCAACGGGCTTCGT
GAAGCTCGACGCGATGGAGAACCCGTATTCGCTGCCCGCGCCGCTCGCGGCCGAGCTCGGCGAGCGGCTCGCGCACGTCG
CGCTGAACCGCTATCCCGCGCCGCGCCCCGCCGCGCTGATCGACCGGCTGCGCGCCGTGACGGGCGTGCCCGCCGCGTGC
GACGTGCTGCTCGGCAACGGCTCGGACGAGATCATCAGCATGCTCGCGATGGCGTGCGCGAAGCCGGGCGCGAAGGTGCT
CGCGCCGGTGCCGGGCTTCGTGATGTACGAGCTGTCGGCGAAGTTCGCGCAGCTCGAGTTCGTCGGCGTGCCGCTTCGCG
CGGACCTCACGCTCGACATCGACGCGATGCTCGCGGCGCTCGCCGAGCACCGGCCGGCGCTCGTCTATCTCGCGTATCCG
AACAACCCGACGGGCACGCTGTACCCGGACGAGGACGTCGAGCGGATCATCGCGGCCGCCGCCACGAGCCTCGTCGTGAT
CGACGAGGCGTACCAGCCGTTCGCGCAGCGCAGTTGGCTGCCGCGCGCGGCCCAGTTCGACAACGTCGTCGTGATGCGCA
CGATGTCGAAGCTCGGCCTGGCGGGCATTCGCCTCGGCTATCTGGTCGGGCTGCCGGCATGGCTCGTGCAGTTCGACAAG
GTGCGCCCGCCGTACAACGTGAACGTGCTGACGCAGGCGGCGGCGGAATTCCTGCTCGAGCGCGTCGACGTGCTCGACGC
GCAGGCCGCGCAACTGCGCGACGCGCGCACGGCGCTCGCGCACGCGATCGGCGCGCTGCCGGGCGCCACCGTGTTCCCGA
GCGCGGGCAATTTCCTGCTCGTACGGGTGCCGGACGCGGCCGCCGTGTTCGATGTGCTTTTGACCGAGCGGGTATTGATC
AAAAACGTGAGTAAAATGCATCCATTGCTCGCCAATTGCGTGCGCGTGACGGTTGGGTCTCCCGAAGAAAACGCGCGCCT
GCTGGCCGCACTGAAGCTGGCGCTGCCCTGA

Upstream 100 bases:

>100_bases
ACCCGAGACCGCCCGGCGAGGCGTCTCGCGCGGCGCGACCGGTGCGCCGCGCGGGACGCCTTGGCCGGGGCCACGCCGGC
GCCCGCGCGCCGTTGCCACC

Downstream 100 bases:

>100_bases
CGGGCCACCCCGGGGCGCCGCCTTTCTCGTCCCCATTTGCCTTAGTCATTTCAAGGAAACACCATGCGCGTGGCGCAAGT
CGTTCGCAACACCAGCGAAA

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 1 [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTTPEDIIRRDVLAMTGYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPAPRPAALIDRLRAVTGVPAAC
DVLLGNGSDEIISMLAMACAKPGAKVLAPVPGFVMYELSAKFAQLEFVGVPLRADLTLDIDAMLAALAEHRPALVYLAYP
NNPTGTLYPDEDVERIIAAAATSLVVIDEAYQPFAQRSWLPRAAQFDNVVVMRTMSKLGLAGIRLGYLVGLPAWLVQFDK
VRPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVFPSAGNFLLVRVPDAAAVFDVLLTERVLI
KNVSKMHPLLANCVRVTVGSPEENARLLAALKLALP

Sequences:

>Translated_356_residues
MTTPEDIIRRDVLAMTGYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPAPRPAALIDRLRAVTGVPAAC
DVLLGNGSDEIISMLAMACAKPGAKVLAPVPGFVMYELSAKFAQLEFVGVPLRADLTLDIDAMLAALAEHRPALVYLAYP
NNPTGTLYPDEDVERIIAAAATSLVVIDEAYQPFAQRSWLPRAAQFDNVVVMRTMSKLGLAGIRLGYLVGLPAWLVQFDK
VRPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVFPSAGNFLLVRVPDAAAVFDVLLTERVLI
KNVSKMHPLLANCVRVTVGSPEENARLLAALKLALP
>Mature_355_residues
TTPEDIIRRDVLAMTGYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPAPRPAALIDRLRAVTGVPAACD
VLLGNGSDEIISMLAMACAKPGAKVLAPVPGFVMYELSAKFAQLEFVGVPLRADLTLDIDAMLAALAEHRPALVYLAYPN
NPTGTLYPDEDVERIIAAAATSLVVIDEAYQPFAQRSWLPRAAQFDNVVVMRTMSKLGLAGIRLGYLVGLPAWLVQFDKV
RPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVFPSAGNFLLVRVPDAAAVFDVLLTERVLIK
NVSKMHPLLANCVRVTVGSPEENARLLAALKLALP

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=363, Percent_Identity=31.129476584022, Blast_Score=130, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322075, Length=365, Percent_Identity=29.041095890411, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 38172; Mature: 38041

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPEDIIRRDVLAMTGYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPA
CCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PRPAALIDRLRAVTGVPAACDVLLGNGSDEIISMLAMACAKPGAKVLAPVPGFVMYELSA
CCHHHHHHHHHHHHCCCHHHHEEECCCHHHHHHHHHHHHCCCCCCEECCCCCCEEEHHHH
KFAQLEFVGVPLRADLTLDIDAMLAALAEHRPALVYLAYPNNPTGTLYPDEDVERIIAAA
HHEEEEEEECCEECCCEECHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHH
ATSLVVIDEAYQPFAQRSWLPRAAQFDNVVVMRTMSKLGLAGIRLGYLVGLPAWLVQFDK
HHHEEEECHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHC
VRPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVFPSAGNFLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
VRVPDAAAVFDVLLTERVLIKNVSKMHPLLANCVRVTVGSPEENARLLAALKLALP
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TTPEDIIRRDVLAMTGYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPA
CCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PRPAALIDRLRAVTGVPAACDVLLGNGSDEIISMLAMACAKPGAKVLAPVPGFVMYELSA
CCHHHHHHHHHHHHCCCHHHHEEECCCHHHHHHHHHHHHCCCCCCEECCCCCCEEEHHHH
KFAQLEFVGVPLRADLTLDIDAMLAALAEHRPALVYLAYPNNPTGTLYPDEDVERIIAAA
HHEEEEEEECCEECCCEECHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHH
ATSLVVIDEAYQPFAQRSWLPRAAQFDNVVVMRTMSKLGLAGIRLGYLVGLPAWLVQFDK
HHHEEEECHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHC
VRPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVFPSAGNFLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
VRVPDAAAVFDVLLTERVLIKNVSKMHPLLANCVRVTVGSPEENARLLAALKLALP
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA