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The map label for this gene is mchE [H]

Identifier: 237814008

GI number: 237814008

Start: 3651753

End: 3653021

Strand: Direct

Name: mchE [H]

Synonym: GBP346_A3792

Alternate gene names: 237814008

Gene position: 3651753-3653021 (Clockwise)

Preceding gene: 237814006

Following gene: 237814009

Centisome position: 89.1

GC content: 67.22

Gene sequence:

>1269_bases
ATGACGCCCAACACTCCACTCTTTCGAACGGCCGCTCAGGAAGCGCAGCGCACGCAGACGCTCGGCGAGATCGTGCTGAT
CCGTCCCGTGTCGTTCGCCGTGCTCGCGAGCGCGGCCGCCAGCATGGCGCTCGGCGTGATCCTGCTCTTCACGTTCGGCA
CCTATACGCGGCGCACGACGGTCGACGGCGTGCTCACGCCGGACACGGGCCTCGTCAAGGTCTATGCGCAGCAGACAGGC
GTCGTGCTGAAGAAGAACGTCGTCGAAGGGCAGCACGTGACGCGCGGACAAGTGCTCTACACGGTGTCGACCGATCTGCA
GAGCGCGGCGGCGGGCCAGACGCAAGCCGCGCTCATCGAGCAGGCTCAGCAGCGCAAGACTTCACTCCAACAGGAGCTAG
ACAAGACCCGGCGTCTGCAACAGGACGAGCGCGACACGCTGCAATCGAAGATCGCGAGCCTGCGCACCGAGCTCGCGGGC
ATCGACGATCAGATCGCCGCGCAACGCACGCGCGCATCGATCGCGGCCGACGCCGCGTCGCGCTACGCCGGCCTGCTCGC
TCAGGACTACATCTCGAAGGATCAGGCACAGCAGCGCCAGGCCGATCTGCTCGATCAGCGCTCGAAGCTGAACAGCCTGA
TGCGCGACCGCGCGAGCACGGCGCAATCGCTGAAGGAGGCGCTCAACGATCTGTCGGGGCTGTCGCTCAAGCAGCAGAAC
CAGTTGTCGCAGATCGACCGCAGCGTGATCGACGTCGACCGCACGCTGATCGAAAGCGAGGCGAAGCGCGAGTTTGTCGT
CACCGCGCCGGAAACGGGCACCGCGACCGCGGTGATCGCCGAGCCGGGCCAGACCGCGGACACGTCGCACCCGCTCGCGA
GCATCGTGCCGACGGGCGCGCATTGGCAAGCGTATCTGTTCGTGCCCAGCGCGGCGGTCGGCTTCGTGCACGTCGGCGAT
CGCGTGCTCGTGCGCTATCAGGCGTATCCGTACCAGAAGTTCGGCCAGTACGAAGCGAGCGTCGTGTCGATCGCGCGCAC
CGCGCTGTCGGCCGCCGAGCTCGCGACGAGCGGCGGCCCGGCCGCGCAGACGGCAAGCGGCACGTACTACCGGATCACGG
TCGCGCTGAATTCGCAGAACGTGATGGCGTACGGCCGGGCGCAGCCGCTGCAGGCCGGCATGGCGTTGCAAGCCGACGTG
CTGCAGGAGCGCCGCCGCCTGTACGAATGGGTGCTCGAACCTCTTTACAGCCTGACGGGCAAACTCTGA

Upstream 100 bases:

>100_bases
GCCGCGGCGCCCGCCGCCGCCCGCCGCGGCGCGCGAACCGTCTGACGACAGCGCGACACGGCTTCGCGACGACATACACG
CTACTTTCGGCAGTCCCTCC

Downstream 100 bases:

>100_bases
CGCGACCCAAGCCTATGTCACTCCTCGATCGCCTCTCGTTCGGCATCGGCAGCAAGCTGCCGATGATCCTGCAGACCGAA
GCCGCCGAATGCGGCCTTGC

Product: auxiliary transport protein, membrane fusion protein family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MTPNTPLFRTAAQEAQRTQTLGEIVLIRPVSFAVLASAAASMALGVILLFTFGTYTRRTTVDGVLTPDTGLVKVYAQQTG
VVLKKNVVEGQHVTRGQVLYTVSTDLQSAAAGQTQAALIEQAQQRKTSLQQELDKTRRLQQDERDTLQSKIASLRTELAG
IDDQIAAQRTRASIAADAASRYAGLLAQDYISKDQAQQRQADLLDQRSKLNSLMRDRASTAQSLKEALNDLSGLSLKQQN
QLSQIDRSVIDVDRTLIESEAKREFVVTAPETGTATAVIAEPGQTADTSHPLASIVPTGAHWQAYLFVPSAAVGFVHVGD
RVLVRYQAYPYQKFGQYEASVVSIARTALSAAELATSGGPAAQTASGTYYRITVALNSQNVMAYGRAQPLQAGMALQADV
LQERRRLYEWVLEPLYSLTGKL

Sequences:

>Translated_422_residues
MTPNTPLFRTAAQEAQRTQTLGEIVLIRPVSFAVLASAAASMALGVILLFTFGTYTRRTTVDGVLTPDTGLVKVYAQQTG
VVLKKNVVEGQHVTRGQVLYTVSTDLQSAAAGQTQAALIEQAQQRKTSLQQELDKTRRLQQDERDTLQSKIASLRTELAG
IDDQIAAQRTRASIAADAASRYAGLLAQDYISKDQAQQRQADLLDQRSKLNSLMRDRASTAQSLKEALNDLSGLSLKQQN
QLSQIDRSVIDVDRTLIESEAKREFVVTAPETGTATAVIAEPGQTADTSHPLASIVPTGAHWQAYLFVPSAAVGFVHVGD
RVLVRYQAYPYQKFGQYEASVVSIARTALSAAELATSGGPAAQTASGTYYRITVALNSQNVMAYGRAQPLQAGMALQADV
LQERRRLYEWVLEPLYSLTGKL
>Mature_421_residues
TPNTPLFRTAAQEAQRTQTLGEIVLIRPVSFAVLASAAASMALGVILLFTFGTYTRRTTVDGVLTPDTGLVKVYAQQTGV
VLKKNVVEGQHVTRGQVLYTVSTDLQSAAAGQTQAALIEQAQQRKTSLQQELDKTRRLQQDERDTLQSKIASLRTELAGI
DDQIAAQRTRASIAADAASRYAGLLAQDYISKDQAQQRQADLLDQRSKLNSLMRDRASTAQSLKEALNDLSGLSLKQQNQ
LSQIDRSVIDVDRTLIESEAKREFVVTAPETGTATAVIAEPGQTADTSHPLASIVPTGAHWQAYLFVPSAAVGFVHVGDR
VLVRYQAYPYQKFGQYEASVVSIARTALSAAELATSGGPAAQTASGTYYRITVALNSQNVMAYGRAQPLQAGMALQADVL
QERRRLYEWVLEPLYSLTGKL

Specific function: Probably involved, in conjunction with mchF, in the secretion of microcin H47 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 45803; Mature: 45672

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPNTPLFRTAAQEAQRTQTLGEIVLIRPVSFAVLASAAASMALGVILLFTFGTYTRRTT
CCCCCCHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VDGVLTPDTGLVKVYAQQTGVVLKKNVVEGQHVTRGQVLYTVSTDLQSAAAGQTQAALIE
ECCEECCCCCEEEEEEHHCCEEEEHHCCCCCCCCCCEEEEEEECCHHHHHCCCHHHHHHH
QAQQRKTSLQQELDKTRRLQQDERDTLQSKIASLRTELAGIDDQIAAQRTRASIAADAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RYAGLLAQDYISKDQAQQRQADLLDQRSKLNSLMRDRASTAQSLKEALNDLSGLSLKQQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
QLSQIDRSVIDVDRTLIESEAKREFVVTAPETGTATAVIAEPGQTADTSHPLASIVPTGA
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCCCCCCCHHHHCCCCC
HWQAYLFVPSAAVGFVHVGDRVLVRYQAYPYQKFGQYEASVVSIARTALSAAELATSGGP
CEEEEEEECCCCEEEEEECCEEEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
AAQTASGTYYRITVALNSQNVMAYGRAQPLQAGMALQADVLQERRRLYEWVLEPLYSLTG
CCCCCCCCEEEEEEEECCCCEEEECCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHC
KL
CC
>Mature Secondary Structure 
TPNTPLFRTAAQEAQRTQTLGEIVLIRPVSFAVLASAAASMALGVILLFTFGTYTRRTT
CCCCCHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VDGVLTPDTGLVKVYAQQTGVVLKKNVVEGQHVTRGQVLYTVSTDLQSAAAGQTQAALIE
ECCEECCCCCEEEEEEHHCCEEEEHHCCCCCCCCCCEEEEEEECCHHHHHCCCHHHHHHH
QAQQRKTSLQQELDKTRRLQQDERDTLQSKIASLRTELAGIDDQIAAQRTRASIAADAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RYAGLLAQDYISKDQAQQRQADLLDQRSKLNSLMRDRASTAQSLKEALNDLSGLSLKQQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
QLSQIDRSVIDVDRTLIESEAKREFVVTAPETGTATAVIAEPGQTADTSHPLASIVPTGA
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCCCCCCCHHHHCCCCC
HWQAYLFVPSAAVGFVHVGDRVLVRYQAYPYQKFGQYEASVVSIARTALSAAELATSGGP
CEEEEEEECCCCEEEEEECCEEEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
AAQTASGTYYRITVALNSQNVMAYGRAQPLQAGMALQADVLQERRRLYEWVLEPLYSLTG
CCCCCCCCEEEEEEEECCCCEEEECCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHC
KL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11181394 [H]