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The map label for this gene is coaE [H]

Identifier: 237813903

GI number: 237813903

Start: 3550307

End: 3550918

Strand: Direct

Name: coaE [H]

Synonym: GBP346_A3682

Alternate gene names: 237813903

Gene position: 3550307-3550918 (Clockwise)

Preceding gene: 237813902

Following gene: 237813904

Centisome position: 86.62

GC content: 67.32

Gene sequence:

>612_bases
ATGTTCTCGGTGGGATTGACGGGCGGCATCGGTAGCGGCAAGACGACCGTGGCCGATTTGTTCGGTAAGCTCGGCGCGAC
GATCGTCGATACCGATCTGATCGCGCACCGCATCACCGCGCCGCAAGGCCTCGCGATGCCGCTCATCGCGCGCGAGTTCG
GCGCGGAATTCGTCGCGGCCGACGGCTCGCTCGATCGCGCGAAGATGCGCGCGCTGGTCTTCAGCGACGAATCCGCGCGC
AAACGGCTCGAAGCGATCACGCATCCGCTGATCCGCGAAGAAACCGAGCGCGAAGCGCGTACGGCCCAAGGCGCATACGT
CGTATTCGTCGTGCCGCTGCTCGTCGAATCGGGCACATGGAAGACGCGCGTCGACCGCGTGCTCGTCGTCGACTGCGACG
TCGAGACGCAAATCGCACGCGTGATGGCCCGCAACGGCTTCACTCGCGCGCAGGTGGAGGCGATCGTCGCGCGGCAGGCG
TCGCGCGACGCGCGTCTCGCCGCCGCCGACGACGTGATCGCCAACGACAATGCGTCCGTCGCCGAGCTCGCCGCCGAAGT
CGCCGCACTGCACCAACGCTATCTTGAATGCGCGGCCGCCGCGCGGAATTGA

Upstream 100 bases:

>100_bases
CTTCGAGGAACCGTTGCCATTCGGCCCGTTCCTCGCGGCGGGCGGCGCCGCGACCCTCTTTTTCGGCACGCCGTTCTACC
TGCTGCTCGGAGGCTGAACC

Downstream 100 bases:

>100_bases
CAAGCTTGCGGCACGCACGTTGCGTGCCGTGCACGCAACCACGCGGCCCATCGTCAGCGCCGAAAAATGGCGCGATTGCT
AGGGTAGACCGTGGGCATTA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MFSVGLTGGIGSGKTTVADLFGKLGATIVDTDLIAHRITAPQGLAMPLIAREFGAEFVAADGSLDRAKMRALVFSDESAR
KRLEAITHPLIREETEREARTAQGAYVVFVVPLLVESGTWKTRVDRVLVVDCDVETQIARVMARNGFTRAQVEAIVARQA
SRDARLAAADDVIANDNASVAELAAEVAALHQRYLECAAAARN

Sequences:

>Translated_203_residues
MFSVGLTGGIGSGKTTVADLFGKLGATIVDTDLIAHRITAPQGLAMPLIAREFGAEFVAADGSLDRAKMRALVFSDESAR
KRLEAITHPLIREETEREARTAQGAYVVFVVPLLVESGTWKTRVDRVLVVDCDVETQIARVMARNGFTRAQVEAIVARQA
SRDARLAAADDVIANDNASVAELAAEVAALHQRYLECAAAARN
>Mature_203_residues
MFSVGLTGGIGSGKTTVADLFGKLGATIVDTDLIAHRITAPQGLAMPLIAREFGAEFVAADGSLDRAKMRALVFSDESAR
KRLEAITHPLIREETEREARTAQGAYVVFVVPLLVESGTWKTRVDRVLVVDCDVETQIARVMARNGFTRAQVEAIVARQA
SRDARLAAADDVIANDNASVAELAAEVAALHQRYLECAAAARN

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=178, Percent_Identity=36.5168539325843, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI191252795, Length=178, Percent_Identity=36.5168539325843, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI110227607, Length=166, Percent_Identity=30.7228915662651, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI110227605, Length=166, Percent_Identity=30.7228915662651, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI110227603, Length=166, Percent_Identity=30.7228915662651, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI110227601, Length=166, Percent_Identity=30.7228915662651, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI205277394, Length=166, Percent_Identity=30.7228915662651, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1786292, Length=198, Percent_Identity=47.979797979798, Blast_Score=174, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17554944, Length=192, Percent_Identity=34.8958333333333, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320402, Length=205, Percent_Identity=31.219512195122, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644728, Length=193, Percent_Identity=31.6062176165803, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24658602, Length=177, Percent_Identity=29.3785310734463, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21749; Mature: 21749

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSVGLTGGIGSGKTTVADLFGKLGATIVDTDLIAHRITAPQGLAMPLIAREFGAEFVAA
CCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEC
DGSLDRAKMRALVFSDESARKRLEAITHPLIREETEREARTAQGAYVVFVVPLLVESGTW
CCCCCHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCC
KTRVDRVLVVDCDVETQIARVMARNGFTRAQVEAIVARQASRDARLAAADDVIANDNASV
HHHHCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCHHCCCCCHH
AELAAEVAALHQRYLECAAAARN
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFSVGLTGGIGSGKTTVADLFGKLGATIVDTDLIAHRITAPQGLAMPLIAREFGAEFVAA
CCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEC
DGSLDRAKMRALVFSDESARKRLEAITHPLIREETEREARTAQGAYVVFVVPLLVESGTW
CCCCCHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCC
KTRVDRVLVVDCDVETQIARVMARNGFTRAQVEAIVARQASRDARLAAADDVIANDNASV
HHHHCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCHHCCCCCHH
AELAAEVAALHQRYLECAAAARN
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA