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The map label for this gene is obgE [H]

Identifier: 237813894

GI number: 237813894

Start: 3542074

End: 3543192

Strand: Reverse

Name: obgE [H]

Synonym: GBP346_A3672

Alternate gene names: 237813894

Gene position: 3543192-3542074 (Counterclockwise)

Preceding gene: 237813896

Following gene: 237813893

Centisome position: 86.45

GC content: 66.22

Gene sequence:

>1119_bases
ATGAAGTTCATTGACGAAGCGCGAATCGAGGTCATCGCCGGAGACGGGGGCGATGGCAGCGCGTCGATGCGCCGCGAGAA
ATTCGTTCCGTTCGGCGGACCGGACGGCGGCGACGGCGGCCGCGGCGGCAGCGTGTACGTGATCGCGGATCGCAACATCA
ATACGCTGATCGACTACCGGTACGCGAAGAAGCACATGGCGCGCAACGGCGAGAACGGCCGCGGTTCGGATTGCTACGGC
AAGGGCGGCGACGACATCACGCTGCGCATGCCGGTCGGCACCGTCATCAACGACATGGACACGGGCGAGCTGATCGCCGA
TCTGACCGAGCACGACCAGAAGGTGCTCGTCGCGAAGGGCGGCGCGGGCGGCCTCGGCAACCTCCATTTCAAGTCGAGCA
CGAACCGCGCGCCGCGCCAGAAGACGGACGGCAAGCCGGGCGAGCGGCGCATGCTGAAGCTCGAGCTGAAGGTGCTCGCG
GACGTCGGCCTGCTCGGAATGCCGAACGCGGGCAAATCGACGTTCATTTCGTCGGTGTCGAACGCGAAGCCGAAGATCGC
CGATTATCCGTTCACGACGCTTGCGCCGAATCTCGGCGTCGTGCGCGTCGGGCCGGGCAAGAGCTTCGTGATTGCCGACA
TTCCGGGTCTGATCGAAGGCGCGGCCGAAGGCGCGGGCCTCGGCCATCAGTTTCTGCGGCATCTGCAACGTACGGGCCTG
CTGCTGCATCTCGTCGATCTCGCGCCGTTCGATGAGAGTGTCGATCCCGTCGCGGAAGCGAGGGCGATCGTCGGCGAGTT
GCGCAAGTACGACGAATCGCTGTACGAGAAGCCGCGCTGGCTCGTGTTGAACAAGCTCGACATGGTGCCGGAGGACGAGC
GCCGCGCGCGCGTCGCCGATTTCATCGAGCGCTTCGGCTGGACGGGGCCCGTGTTCGAGATCTCCGCGCTGACGGGGCAG
GGCTGCGAGGGCCTCGTTTATGCAATCCACGATTATCTCGTCGAGCATTCGGACGCGCATCGCGCCGAGCTCGCTGAGGA
TTTGGCGTCGGACGTGCGCTTTCGCGATGCGCCCGGCGCAGGCGGCGAGCCGCACGAGCGCGACGCCGGCGCGCACTGA

Upstream 100 bases:

>100_bases
AAGCATCCGGTGCGCGCGTCGGCCGTTCGGCCGATTGGTCAAGCGCGGCGCCGCGCGGCACAATAGCGGGAATGGCGGTA
CATATTGGACGGAGTGACGG

Downstream 100 bases:

>100_bases
GCGTCTCGTCCATCGCCCATGAAGCCGGGCGGCGCGGCCGGCGTACGGGATTCAATCGCGCATCACTCAAGGAGACAGCG
CACGATGCGTTCGATCATCG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYVIADRNINTLIDYRYAKKHMARNGENGRGSDCYG
KGGDDITLRMPVGTVINDMDTGELIADLTEHDQKVLVAKGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPGKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHLVDLAPFDESVDPVAEARAIVGELRKYDESLYEKPRWLVLNKLDMVPEDERRARVADFIERFGWTGPVFEISALTGQ
GCEGLVYAIHDYLVEHSDAHRAELAEDLASDVRFRDAPGAGGEPHERDAGAH

Sequences:

>Translated_372_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYVIADRNINTLIDYRYAKKHMARNGENGRGSDCYG
KGGDDITLRMPVGTVINDMDTGELIADLTEHDQKVLVAKGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPGKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHLVDLAPFDESVDPVAEARAIVGELRKYDESLYEKPRWLVLNKLDMVPEDERRARVADFIERFGWTGPVFEISALTGQ
GCEGLVYAIHDYLVEHSDAHRAELAEDLASDVRFRDAPGAGGEPHERDAGAH
>Mature_372_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYVIADRNINTLIDYRYAKKHMARNGENGRGSDCYG
KGGDDITLRMPVGTVINDMDTGELIADLTEHDQKVLVAKGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPGKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHLVDLAPFDESVDPVAEARAIVGELRKYDESLYEKPRWLVLNKLDMVPEDERRARVADFIERFGWTGPVFEISALTGQ
GCEGLVYAIHDYLVEHSDAHRAELAEDLASDVRFRDAPGAGGEPHERDAGAH

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=324, Percent_Identity=39.1975308641975, Blast_Score=188, Evalue=7e-48,
Organism=Homo sapiens, GI111955139, Length=384, Percent_Identity=34.375, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI111955063, Length=286, Percent_Identity=32.1678321678322, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI58761500, Length=136, Percent_Identity=32.3529411764706, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4758796, Length=119, Percent_Identity=33.6134453781513, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI4557537, Length=121, Percent_Identity=33.0578512396694, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1789574, Length=336, Percent_Identity=58.3333333333333, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=36, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=327, Percent_Identity=37.6146788990826, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=333, Percent_Identity=29.7297297297297, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=33.0935251798561, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71981008, Length=94, Percent_Identity=36.1702127659575, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=184, Percent_Identity=38.0434782608696, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6321773, Length=156, Percent_Identity=29.4871794871795, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319281, Length=89, Percent_Identity=37.0786516853933, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24585318, Length=292, Percent_Identity=41.4383561643836, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI20129375, Length=336, Percent_Identity=37.5, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24640873, Length=135, Percent_Identity=34.0740740740741, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24640877, Length=135, Percent_Identity=34.0740740740741, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24640875, Length=135, Percent_Identity=34.0740740740741, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21356473, Length=87, Percent_Identity=39.0804597701149, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 40082; Mature: 40082

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYVIADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHH
YAKKHMARNGENGRGSDCYGKGGDDITLRMPVGTVINDMDTGELIADLTEHDQKVLVAKG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCCCHHHHHHHHHHCCCEEEEEEC
GAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCCCCCCCCCHHHEEHHHHHHHHCCCCCCCCCCCHHHHHHHHH
NAKPKIADYPFTTLAPNLGVVRVGPGKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
CCCCCCCCCCHHHHCCCCCEEEECCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHCCC
LLHLVDLAPFDESVDPVAEARAIVGELRKYDESLYEKPRWLVLNKLDMVPEDERRARVAD
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHH
FIERFGWTGPVFEISALTGQGCEGLVYAIHDYLVEHSDAHRAELAEDLASDVRFRDAPGA
HHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEECCCCCC
GGEPHERDAGAH
CCCCCCCCCCCC
>Mature Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYVIADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHH
YAKKHMARNGENGRGSDCYGKGGDDITLRMPVGTVINDMDTGELIADLTEHDQKVLVAKG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCCCHHHHHHHHHHCCCEEEEEEC
GAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCCCCCCCCCHHHEEHHHHHHHHCCCCCCCCCCCHHHHHHHHH
NAKPKIADYPFTTLAPNLGVVRVGPGKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
CCCCCCCCCCHHHHCCCCCEEEECCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHCCC
LLHLVDLAPFDESVDPVAEARAIVGELRKYDESLYEKPRWLVLNKLDMVPEDERRARVAD
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHH
FIERFGWTGPVFEISALTGQGCEGLVYAIHDYLVEHSDAHRAELAEDLASDVRFRDAPGA
HHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEECCCCCC
GGEPHERDAGAH
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA