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The map label for this gene is hrcA [H]

Identifier: 237813685

GI number: 237813685

Start: 3343544

End: 3344761

Strand: Reverse

Name: hrcA [H]

Synonym: GBP346_A3462

Alternate gene names: 237813685

Gene position: 3344761-3343544 (Counterclockwise)

Preceding gene: 237813688

Following gene: 237813684

Centisome position: 81.61

GC content: 66.67

Gene sequence:

>1218_bases
ATGCCGGGCGTGTTGCTGCGCCCGACGAGCGCGACGGTATGGAATTGGTGGCCGATTTTCATGCCGGCATTACACCATAG
CTCGATGACGAAAAGAACCGCCCGCCGGCGGCCGGCCGGCAAAACGGGCGCGGGGGCGGCGAGGCGCGCAAGCGGCGCTC
GCGGGCGCCGCCCGGTTGCGCTAAAATTTTCCATCATGTTAGATCCACGCGCACGAACCCTCCTCAAGACACTGATCGAG
CGGTATATCGCCGACGGTCAGCCGGTCGGATCGCGCACGTTGTCTCGTTATTCCGGGCTCGAGCTGAGCCCGGCGACGAT
CCGCAACGTGATGTCCGATCTGGAGGAGCTCGGCCTCGTGTCGAGCCCGCATACGTCGGCCGGCCGGGTACCGACGCCGC
GCGGCTACCGGCTGTTCGTCGACACGATGCTGACCGTCGAGTCGCCGATCGATTCCGACGCGGTCACGCGGCTCGTGCAG
ACCACGCTGCAGGCGGGCGAGCCGCAGCAGCGGGTCGTCGCGGCCGCGGCGAGCGTGCTGTCGAACCTGTCGCAGTTCGC
GGGCGTCGTGCTCACGCCGCGCCGCAGCCACGTGTTCAAGCAGATCGAATTCCTGCGCCTGTCGGACAAGCGGATCCTCC
TCATCATCGTGACGCCCGAAGGCGACGTGCAGAACCGCATGATCGCGACGCAGCGCGACTACGCGCCCGCGCAGCTCACC
GAGGCGTCGAACTACATCAACGCGCACTTCGCCGGCCTGTCGTTCGACGAGGTGCGCCGCCGGCTGCGCGAGGAAATCGA
TCAGTTGCGCGGCGACATGACGGCGCTGATGCACGCGGCCGTCACGGCGAGCACCGAGGAGCCCGACGACGAGGAAACCG
TGCTGATCTCCGGCGAGCGCAACCTGCTCGAGGTGGCCGATCTGTCGTCCGACATGGCGCGCCTGCGCAAGCTGTTCGAC
GTGTTCGACCAGAAGACGAGCCTGCTGCAACTGCTCGACGTGTCGAGCCATGCGCAAGGGGTGCAGATCTTCATCGGCGG
CGAATCGACGCTCGTGCCGATCGACGAGATGAGCGTCGTGACCGCGCCGTACGAGGTCAACGGCAAGATCGTCGGCACGC
TCGGCGTGATCGGCCCGACGCGCATGGCTTACAACCGCGTGATTCCGATCGTCGACATCACCGCGCGCCTGCTGTCGCTC
ACGCTCAGCCAGCAGTAA

Upstream 100 bases:

>100_bases
GTAGCCGGCGCTGCCGATCGCCTGCGCGGTATCCGCCTCGAACACGACTTCGAAGCCGCGCTTCGCGATGCACGCGGCGA
GCGACGCGAGCGGCTCGGCG

Downstream 100 bases:

>100_bases
CCGGTTCCTTTCGCCTTTCATCGTCTTTCGTCATACTTTTGCGCGCGCTTTTGCGGCATCCGGCGCTGTTTTTTCCGCTC
CGGCTACGTCATCGCCATCG

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MPGVLLRPTSATVWNWWPIFMPALHHSSMTKRTARRRPAGKTGAGAARRASGARGRRPVALKFSIMLDPRARTLLKTLIE
RYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHTSAGRVPTPRGYRLFVDTMLTVESPIDSDAVTRLVQ
TTLQAGEPQQRVVAAAASVLSNLSQFAGVVLTPRRSHVFKQIEFLRLSDKRILLIIVTPEGDVQNRMIATQRDYAPAQLT
EASNYINAHFAGLSFDEVRRRLREEIDQLRGDMTALMHAAVTASTEEPDDEETVLISGERNLLEVADLSSDMARLRKLFD
VFDQKTSLLQLLDVSSHAQGVQIFIGGESTLVPIDEMSVVTAPYEVNGKIVGTLGVIGPTRMAYNRVIPIVDITARLLSL
TLSQQ

Sequences:

>Translated_405_residues
MPGVLLRPTSATVWNWWPIFMPALHHSSMTKRTARRRPAGKTGAGAARRASGARGRRPVALKFSIMLDPRARTLLKTLIE
RYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHTSAGRVPTPRGYRLFVDTMLTVESPIDSDAVTRLVQ
TTLQAGEPQQRVVAAAASVLSNLSQFAGVVLTPRRSHVFKQIEFLRLSDKRILLIIVTPEGDVQNRMIATQRDYAPAQLT
EASNYINAHFAGLSFDEVRRRLREEIDQLRGDMTALMHAAVTASTEEPDDEETVLISGERNLLEVADLSSDMARLRKLFD
VFDQKTSLLQLLDVSSHAQGVQIFIGGESTLVPIDEMSVVTAPYEVNGKIVGTLGVIGPTRMAYNRVIPIVDITARLLSL
TLSQQ
>Mature_404_residues
PGVLLRPTSATVWNWWPIFMPALHHSSMTKRTARRRPAGKTGAGAARRASGARGRRPVALKFSIMLDPRARTLLKTLIER
YIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHTSAGRVPTPRGYRLFVDTMLTVESPIDSDAVTRLVQT
TLQAGEPQQRVVAAAASVLSNLSQFAGVVLTPRRSHVFKQIEFLRLSDKRILLIIVTPEGDVQNRMIATQRDYAPAQLTE
ASNYINAHFAGLSFDEVRRRLREEIDQLRGDMTALMHAAVTASTEEPDDEETVLISGERNLLEVADLSSDMARLRKLFDV
FDQKTSLLQLLDVSSHAQGVQIFIGGESTLVPIDEMSVVTAPYEVNGKIVGTLGVIGPTRMAYNRVIPIVDITARLLSLT
LSQQ

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 44561; Mature: 44430

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGVLLRPTSATVWNWWPIFMPALHHSSMTKRTARRRPAGKTGAGAARRASGARGRRPVA
CCCCEECCCCCCEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCEE
LKFSIMLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLV
EEEEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
SSPHTSAGRVPTPRGYRLFVDTMLTVESPIDSDAVTRLVQTTLQAGEPQQRVVAAAASVL
CCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
SNLSQFAGVVLTPRRSHVFKQIEFLRLSDKRILLIIVTPEGDVQNRMIATQRDYAPAQLT
HHHHHHCCEEECCCHHHHHHHHHHHEECCCEEEEEEECCCCCHHHCEECCCCCCCCHHHH
EASNYINAHFAGLSFDEVRRRLREEIDQLRGDMTALMHAAVTASTEEPDDEETVLISGER
HHCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
NLLEVADLSSDMARLRKLFDVFDQKTSLLQLLDVSSHAQGVQIFIGGESTLVPIDEMSVV
CCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCEEE
TAPYEVNGKIVGTLGVIGPTRMAYNRVIPIVDITARLLSLTLSQQ
ECCEEECCEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PGVLLRPTSATVWNWWPIFMPALHHSSMTKRTARRRPAGKTGAGAARRASGARGRRPVA
CCCEECCCCCCEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCEE
LKFSIMLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLV
EEEEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
SSPHTSAGRVPTPRGYRLFVDTMLTVESPIDSDAVTRLVQTTLQAGEPQQRVVAAAASVL
CCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
SNLSQFAGVVLTPRRSHVFKQIEFLRLSDKRILLIIVTPEGDVQNRMIATQRDYAPAQLT
HHHHHHCCEEECCCHHHHHHHHHHHEECCCEEEEEEECCCCCHHHCEECCCCCCCCHHHH
EASNYINAHFAGLSFDEVRRRLREEIDQLRGDMTALMHAAVTASTEEPDDEETVLISGER
HHCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
NLLEVADLSSDMARLRKLFDVFDQKTSLLQLLDVSSHAQGVQIFIGGESTLVPIDEMSVV
CCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCEEE
TAPYEVNGKIVGTLGVIGPTRMAYNRVIPIVDITARLLSLTLSQQ
ECCEEECCEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA