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The map label for this gene is pabB [H]

Identifier: 237813676

GI number: 237813676

Start: 3334830

End: 3336836

Strand: Reverse

Name: pabB [H]

Synonym: GBP346_A3453

Alternate gene names: 237813676

Gene position: 3336836-3334830 (Counterclockwise)

Preceding gene: 237813677

Following gene: 237813669

Centisome position: 81.41

GC content: 72.4

Gene sequence:

>2007_bases
ATGACTGACGAAGCGGGCGCGGTTTTCGCGCTCTTCGACGATTGCGACTCGACCGCGGCGGCGCGCTCGAGTCGCTTGTA
TTCGGGCTTCTCGCACGAGCGGGCCTGCGCCGATCCGGCCGGCCTCGACGCGGTGTGCGCGGCCGTCGCCGACGACGCGC
GGCGCGGGCTGCACGCCGTCGTGCTCGGCGACTACGAGTTCGGGCGCGACCTGCAGCTCGGCAAGCGCGGCGGCGGCGCG
TTGCGGTTCCTGCTGTTCGCCGAATGCAGGATGCTCTCGCGCGAGGAGGCCGACGCGTGGCTCGCGTCGCGCGACGGCGG
CTCGGCCGAGCCGTCGGCGGCGGGCGTCGCGCACGTGACGAAGAGCGTCGCGCGCGACGCGTTCGACGCGGCGATCGCCG
CCGTGCACGATGCGCTGCGCGCGGGCGATTCGTATCAGATCAACTACACGTACCGGCTGCATTTCGATGCGTTCGGCGCG
CCGCTCGCGCTGTATCGCCGCCTGCGGGCGCGCCAGCCGGTGCGCTACGGCGCGCTCGTCGCGCTGCCGGGCGGCGCGTG
GATCGTATCGTGCTCGCCCGAGCTGTTCGTCGAGAAGACGGGCGCGTTGCTGCGCGCGCGGCCGATGAAAGGCACCGCGC
CTCGCTCGGACGATCCGCGCGAGGATGCGGCCGCCGCGCGCTTTCTCGCGAACGATGCGAAGAATCGCGCCGAGAACGTG
ATGATCGTCGATCTGCTGCGCAACGATCTCGCGCGCATCGCGCGCACCGGATCGGTGACGGTGCCGGCGTTGTTCTCGGT
CGAGCCGTATGCGTCGGTGTGGCAGATGACGTCGACGGTCGAGGCGGGCATCGTCGAAGGCGCGACGTTCGCCGACGTGC
TGCGCGCGCTCTTTCCGTGCGGCTCGATCACGGGCGCGCCGAAGCACAGGACGATGCAACTGATCGATGCGCTCGAGACG
ACGCCGCGCGGGCTCTATACGGGCGCGATCGGCTGGCTCGATGCGGAGGCGCGTGCGGACGGCGCCGAGCCTGCCGCAGG
CGCGTTCGCGCCGGAGCGTGCGGCGAGCCCGGCCGCAGGCACGGCGTCGGATGGCGCGTGCGCGGGCGAAACCGCGTCGA
AGCAGGCGTCGAAGCGTGCCGGCGCGACAAGCCCGGCCGGCGCGTGCGGCGATTTCTGCCTGTCGGTCGCAATCCGCACG
CTGACGCTCGACGCGCCGTCGGCCGGCGGCGAGCGGCGCGGCACGATGGGCGTCGGCGCGGGCATCGTGCTCGACAGCGT
TGCCGCCGACGAATACGCGGAGTGCGAATTGAAGGCGCGTTTCCTGACCGACGCCGAGCCCGGCTTCCAGTTGTTCGAGA
CGATGCTCGCCACGCGTGACGCCGGCGTGCGCCATCTCGACCGCCATGTCGCGCGGCTGCGCGCGAGTGCCGACGCGCTC
GGCTTCGCGTTCGACGAAGCGGCGGCCAGGCAGCGCATCGGCGCGCGCTGCGTGCAGCTCGGCGACGGCGAGCATCGCTT
GCGCGTCGCGCTCGCGAAGGACGGCGTGCTCGACATCGTGGCCGCGCCGCTCGCGCCGCTCGCGGGCGCCGCGGTGGCCG
TATTGCTCGCGCCCGAGCACGGGTTCGCGCCGATGCGCTCGGACGACTTCCTGCTCGCGCACAAGACGACGCGCCGCGCC
GATTACGATCGCGCGTGGAAAGCCGCGCAGGCGTGCGGTGCGTTCGACATGCTGTTCTTCAACGAACGCGGCGAATTGAC
CGAAGGCGGGCGCACGAGCGTATTCGTGAAGCTGGCCGGGCGCTGGTTCACGCCGCCGCTGTCGTCGGGCGTGTTGCCGG
GCGTGATGCGCGGCGCGCTGCTCGACGATCCGGCATGGCAGGCGTCCGAGCGTGTAATGACGCTGGACGACGTGCTGCGC
GCCGACGCGCTGATGCTGACGAACGCGTTGCGCGGCGCGATGCCCGCGCAACTCGTGCGGGCCGCCGGCGCGGCGGCACC
GCGATAG

Upstream 100 bases:

>100_bases
AGGAGGCCCGCGTCACAGCCCGCAGAGCAAGAGCTGGTTCGACCGCGTGAAGAGCTTCTTCGAGTGACGCCCGGCGTGCG
GTCCGCAGGTGAGAGGCAGG

Downstream 100 bases:

>100_bases
GCGCGCGAAGAGCGGCCGGGCGGCCGCACGCATCGCCCTCGCGCTTCGGCTCGCAAAAAGCGGCATCCCGCACGTGCGGG
ATGCCGCTTTTTTTGTCGAG

Product: PabB

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 668; Mature: 667

Protein sequence:

>668_residues
MTDEAGAVFALFDDCDSTAAARSSRLYSGFSHERACADPAGLDAVCAAVADDARRGLHAVVLGDYEFGRDLQLGKRGGGA
LRFLLFAECRMLSREEADAWLASRDGGSAEPSAAGVAHVTKSVARDAFDAAIAAVHDALRAGDSYQINYTYRLHFDAFGA
PLALYRRLRARQPVRYGALVALPGGAWIVSCSPELFVEKTGALLRARPMKGTAPRSDDPREDAAAARFLANDAKNRAENV
MIVDLLRNDLARIARTGSVTVPALFSVEPYASVWQMTSTVEAGIVEGATFADVLRALFPCGSITGAPKHRTMQLIDALET
TPRGLYTGAIGWLDAEARADGAEPAAGAFAPERAASPAAGTASDGACAGETASKQASKRAGATSPAGACGDFCLSVAIRT
LTLDAPSAGGERRGTMGVGAGIVLDSVAADEYAECELKARFLTDAEPGFQLFETMLATRDAGVRHLDRHVARLRASADAL
GFAFDEAAARQRIGARCVQLGDGEHRLRVALAKDGVLDIVAAPLAPLAGAAVAVLLAPEHGFAPMRSDDFLLAHKTTRRA
DYDRAWKAAQACGAFDMLFFNERGELTEGGRTSVFVKLAGRWFTPPLSSGVLPGVMRGALLDDPAWQASERVMTLDDVLR
ADALMLTNALRGAMPAQLVRAAGAAAPR

Sequences:

>Translated_668_residues
MTDEAGAVFALFDDCDSTAAARSSRLYSGFSHERACADPAGLDAVCAAVADDARRGLHAVVLGDYEFGRDLQLGKRGGGA
LRFLLFAECRMLSREEADAWLASRDGGSAEPSAAGVAHVTKSVARDAFDAAIAAVHDALRAGDSYQINYTYRLHFDAFGA
PLALYRRLRARQPVRYGALVALPGGAWIVSCSPELFVEKTGALLRARPMKGTAPRSDDPREDAAAARFLANDAKNRAENV
MIVDLLRNDLARIARTGSVTVPALFSVEPYASVWQMTSTVEAGIVEGATFADVLRALFPCGSITGAPKHRTMQLIDALET
TPRGLYTGAIGWLDAEARADGAEPAAGAFAPERAASPAAGTASDGACAGETASKQASKRAGATSPAGACGDFCLSVAIRT
LTLDAPSAGGERRGTMGVGAGIVLDSVAADEYAECELKARFLTDAEPGFQLFETMLATRDAGVRHLDRHVARLRASADAL
GFAFDEAAARQRIGARCVQLGDGEHRLRVALAKDGVLDIVAAPLAPLAGAAVAVLLAPEHGFAPMRSDDFLLAHKTTRRA
DYDRAWKAAQACGAFDMLFFNERGELTEGGRTSVFVKLAGRWFTPPLSSGVLPGVMRGALLDDPAWQASERVMTLDDVLR
ADALMLTNALRGAMPAQLVRAAGAAAPR
>Mature_667_residues
TDEAGAVFALFDDCDSTAAARSSRLYSGFSHERACADPAGLDAVCAAVADDARRGLHAVVLGDYEFGRDLQLGKRGGGAL
RFLLFAECRMLSREEADAWLASRDGGSAEPSAAGVAHVTKSVARDAFDAAIAAVHDALRAGDSYQINYTYRLHFDAFGAP
LALYRRLRARQPVRYGALVALPGGAWIVSCSPELFVEKTGALLRARPMKGTAPRSDDPREDAAAARFLANDAKNRAENVM
IVDLLRNDLARIARTGSVTVPALFSVEPYASVWQMTSTVEAGIVEGATFADVLRALFPCGSITGAPKHRTMQLIDALETT
PRGLYTGAIGWLDAEARADGAEPAAGAFAPERAASPAAGTASDGACAGETASKQASKRAGATSPAGACGDFCLSVAIRTL
TLDAPSAGGERRGTMGVGAGIVLDSVAADEYAECELKARFLTDAEPGFQLFETMLATRDAGVRHLDRHVARLRASADALG
FAFDEAAARQRIGARCVQLGDGEHRLRVALAKDGVLDIVAAPLAPLAGAAVAVLLAPEHGFAPMRSDDFLLAHKTTRRAD
YDRAWKAAQACGAFDMLFFNERGELTEGGRTSVFVKLAGRWFTPPLSSGVLPGVMRGALLDDPAWQASERVMTLDDVLRA
DALMLTNALRGAMPAQLVRAAGAAAPR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=235, Percent_Identity=41.7021276595745, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1787518, Length=223, Percent_Identity=31.8385650224215, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786809, Length=177, Percent_Identity=27.1186440677966, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=213, Percent_Identity=31.924882629108, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6324361, Length=240, Percent_Identity=29.5833333333333, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 70310; Mature: 70179

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDEAGAVFALFDDCDSTAAARSSRLYSGFSHERACADPAGLDAVCAAVADDARRGLHAV
CCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEE
VLGDYEFGRDLQLGKRGGGALRFLLFAECRMLSREEADAWLASRDGGSAEPSAAGVAHVT
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
KSVARDAFDAAIAAVHDALRAGDSYQINYTYRLHFDAFGAPLALYRRLRARQPVRYGALV
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEE
ALPGGAWIVSCSPELFVEKTGALLRARPMKGTAPRSDDPREDAAAARFLANDAKNRAENV
EECCCCEEEECCHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCE
MIVDLLRNDLARIARTGSVTVPALFSVEPYASVWQMTSTVEAGIVEGATFADVLRALFPC
EEHHHHHHHHHHHHHCCCEEECEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
GSITGAPKHRTMQLIDALETTPRGLYTGAIGWLDAEARADGAEPAAGAFAPERAASPAAG
CCCCCCCCHHHHHHHHHHHCCCCCEEECCCEEECCHHCCCCCCCCCCCCCCHHCCCCCCC
TASDGACAGETASKQASKRAGATSPAGACGDFCLSVAIRTLTLDAPSAGGERRGTMGVGA
CCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCC
GIVLDSVAADEYAECELKARFLTDAEPGFQLFETMLATRDAGVRHLDRHVARLRASADAL
HHHHHHHHCCCHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFAFDEAAARQRIGARCVQLGDGEHRLRVALAKDGVLDIVAAPLAPLAGAAVAVLLAPEH
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHEEEEEECCCC
GFAPMRSDDFLLAHKTTRRADYDRAWKAAQACGAFDMLFFNERGELTEGGRTSVFVKLAG
CCCCCCCCCEEEEECHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEEECC
RWFTPPLSSGVLPGVMRGALLDDPAWQASERVMTLDDVLRADALMLTNALRGAMPAQLVR
CCCCCCCCCCCCHHHHHCCCCCCCCCHHHCCEECHHHHHHHHHHHHHHHHHCCHHHHHHH
AAGAAAPR
HHCCCCCC
>Mature Secondary Structure 
TDEAGAVFALFDDCDSTAAARSSRLYSGFSHERACADPAGLDAVCAAVADDARRGLHAV
CCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEE
VLGDYEFGRDLQLGKRGGGALRFLLFAECRMLSREEADAWLASRDGGSAEPSAAGVAHVT
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
KSVARDAFDAAIAAVHDALRAGDSYQINYTYRLHFDAFGAPLALYRRLRARQPVRYGALV
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEE
ALPGGAWIVSCSPELFVEKTGALLRARPMKGTAPRSDDPREDAAAARFLANDAKNRAENV
EECCCCEEEECCHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCE
MIVDLLRNDLARIARTGSVTVPALFSVEPYASVWQMTSTVEAGIVEGATFADVLRALFPC
EEHHHHHHHHHHHHHCCCEEECEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
GSITGAPKHRTMQLIDALETTPRGLYTGAIGWLDAEARADGAEPAAGAFAPERAASPAAG
CCCCCCCCHHHHHHHHHHHCCCCCEEECCCEEECCHHCCCCCCCCCCCCCCHHCCCCCCC
TASDGACAGETASKQASKRAGATSPAGACGDFCLSVAIRTLTLDAPSAGGERRGTMGVGA
CCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCC
GIVLDSVAADEYAECELKARFLTDAEPGFQLFETMLATRDAGVRHLDRHVARLRASADAL
HHHHHHHHCCCHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFAFDEAAARQRIGARCVQLGDGEHRLRVALAKDGVLDIVAAPLAPLAGAAVAVLLAPEH
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHEEEEEECCCC
GFAPMRSDDFLLAHKTTRRADYDRAWKAAQACGAFDMLFFNERGELTEGGRTSVFVKLAG
CCCCCCCCCEEEEECHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEEECC
RWFTPPLSSGVLPGVMRGALLDDPAWQASERVMTLDDVLRADALMLTNALRGAMPAQLVR
CCCCCCCCCCCCHHHHHCCCCCCCCCHHHCCEECHHHHHHHHHHHHHHHHHCCHHHHHHH
AAGAAAPR
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]