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The map label for this gene is gmhA [H]

Identifier: 237813643

GI number: 237813643

Start: 3301600

End: 3302178

Strand: Reverse

Name: gmhA [H]

Synonym: GBP346_A3420

Alternate gene names: 237813643

Gene position: 3302178-3301600 (Counterclockwise)

Preceding gene: 237813644

Following gene: 237813642

Centisome position: 80.57

GC content: 60.79

Gene sequence:

>579_bases
TTGACGTACATCACGAACAGCATCGCCGAGGCCCAGCGGGTAATGGCCGCGATGCTGGCAGACGAACGGTTGCTTGCGAC
GGTTCAGAAAGTTGCCGATGCCTGCATTGCGTCCATCGCTCAAGGCGGCAAGGTGTTGCTCGCCGGTAACGGCGGAAGCG
CGGCTGATGCGCAGCATATCGCAGGGGAGTTCGTCAGCCGGTTTGCTTTCGATCGGCCCGGGCTGCCGGCAGTGGCGTTG
ACGACGGACACGTCCATTCTCACGGCGATCGGAAACGATTACGGCTACGAGAAACTGTTTTCCCGTCAGGTTCAGGCGCT
CGGCAACAAGGGCGACGTGCTGATCGGTTATTCGACTTCCGGAAAGTCCCCGAACATACTGGCGGCTTTTCGCGAAGCGA
AGGCAAAGGGGATGACGTGCGTCGGCTTCACCGGCAATCGCGGCGGAGAAATGCGCGAGCTGTGCGACTTGCTGCTCGAA
GTCCCGTCGGCCGACACCCCGAAGATCCAGGAGGGGCACCTGGTTCTCGGACATATCGTTTGCGGGCTGGTCGAGCACTC
CATTTTCGGGAAGCAGTGA

Upstream 100 bases:

>100_bases
AGAAGCGCATGGATCTGATCAGGACGCTTGGCGAATACGACGGACAAGTTAGCAACTGCCACTTTACGAAGAACGGGACG
CAGGCATGGAGAATCGCGAA

Downstream 100 bases:

>100_bases
AATGAGAGAAGCGATCATCTTGGCCGGAGGGTTCGGTACGCGCTTGCGCACGGTCGTCTCCGACGTTCCCAAGCCGATGG
CGCCTATTGCCGGCAGGCCA

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MTYITNSIAEAQRVMAAMLADERLLATVQKVADACIASIAQGGKVLLAGNGGSAADAQHIAGEFVSRFAFDRPGLPAVAL
TTDTSILTAIGNDYGYEKLFSRQVQALGNKGDVLIGYSTSGKSPNILAAFREAKAKGMTCVGFTGNRGGEMRELCDLLLE
VPSADTPKIQEGHLVLGHIVCGLVEHSIFGKQ

Sequences:

>Translated_192_residues
MTYITNSIAEAQRVMAAMLADERLLATVQKVADACIASIAQGGKVLLAGNGGSAADAQHIAGEFVSRFAFDRPGLPAVAL
TTDTSILTAIGNDYGYEKLFSRQVQALGNKGDVLIGYSTSGKSPNILAAFREAKAKGMTCVGFTGNRGGEMRELCDLLLE
VPSADTPKIQEGHLVLGHIVCGLVEHSIFGKQ
>Mature_191_residues
TYITNSIAEAQRVMAAMLADERLLATVQKVADACIASIAQGGKVLLAGNGGSAADAQHIAGEFVSRFAFDRPGLPAVALT
TDTSILTAIGNDYGYEKLFSRQVQALGNKGDVLIGYSTSGKSPNILAAFREAKAKGMTCVGFTGNRGGEMRELCDLLLEV
PSADTPKIQEGHLVLGHIVCGLVEHSIFGKQ

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=183, Percent_Identity=41.5300546448087, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI1789539, Length=184, Percent_Identity=38.5869565217391, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20142; Mature: 20011

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYITNSIAEAQRVMAAMLADERLLATVQKVADACIASIAQGGKVLLAGNGGSAADAQHI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
AGEFVSRFAFDRPGLPAVALTTDTSILTAIGNDYGYEKLFSRQVQALGNKGDVLIGYSTS
HHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
GKSPNILAAFREAKAKGMTCVGFTGNRGGEMRELCDLLLEVPSADTPKIQEGHLVLGHIV
CCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
CGLVEHSIFGKQ
HHHHHHHHCCCC
>Mature Secondary Structure 
TYITNSIAEAQRVMAAMLADERLLATVQKVADACIASIAQGGKVLLAGNGGSAADAQHI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
AGEFVSRFAFDRPGLPAVALTTDTSILTAIGNDYGYEKLFSRQVQALGNKGDVLIGYSTS
HHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
GKSPNILAAFREAKAKGMTCVGFTGNRGGEMRELCDLLLEVPSADTPKIQEGHLVLGHIV
CCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
CGLVEHSIFGKQ
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11373120; 12101286 [H]