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The map label for this gene is epsA [H]

Identifier: 237813623

GI number: 237813623

Start: 3277706

End: 3278974

Strand: Reverse

Name: epsA [H]

Synonym: GBP346_A3400

Alternate gene names: 237813623

Gene position: 3278974-3277706 (Counterclockwise)

Preceding gene: 237813624

Following gene: 237813622

Centisome position: 80.0

GC content: 70.53

Gene sequence:

>1269_bases
TTGAAGCCGTTCGTGCGGCGCTTGCGGCCGGAACCGGCCGGAACGAGAAAATCGATAGAGGTGTGGATGGGTAGTCTGGG
GGAAGCAGGCGGCATCGCGCCGCCGAAACGCACGTGCGGCGCGCGCGTGCGTCGGCTGATGAAGCGGGTGACGCTGTGCG
CGGCGCTTGCGGCATTGAGCGCGTGCGGCGTCGCGCCCGGCATGCGGATGAAACAGCCGGCGAACGTGCCGGTGTCGAGC
GCGGCAGCGGACGCGCCGGCCGAGGCCGGACGCAAGCCGCGCGGCGAGCAGCTGCCGGTGCCGATCACCGACATCGATCT
GAGCCTGATCCGGACGCTGCGCGATGCGCAACAGGCGCCGCGCCGCGCGGCCGATCTCGTATCGCCGGCGTCGGGCTATA
CGATCGGGCGCGGCGACGTGCTGCAGATCACGGTCTGGGACCACCCCGAGCTCGCGGCGGCGCTCGGCACGCAGCAGCAG
ACGGCGGCGCGCGCGGCCGATGCGCCGGCGGGCTTCGTCGTCGATCAGGACGGCACGCTCCAGTACCCGTACGTCGGGCG
CATCGCGGTGGCGGGCCTGAAGCCGGAACAGGTTCAGGCGCGGCTCGCGCGCCAGCTCGCGCAGACGTTCCGCGATCCGC
AGGTGACGGTGCGCATCGCATCGTTTCGCGCGAAGCAGGTCTACATCGAAGGCGAGGTGCATACGCCCGGTTCGCAGGCG
CTCAACGACATCCCGATGACGCTGTACGACGCGGTGAGCCGCGCGGGCGGCTTCTCGGCGAGCGCGGACCAGCGGCGCGT
GACGCTCGTGCGCGACGGCGTCGAACGAAGGATCGATCTGTCGGGCGCTGCACAGGGCGTCAATCCGTCACGGATCGTGC
TGCGCGACGGCGATTTGCTGCGCATTCCGCCGCGCGACGAAAGCGGCGTGTTCGTGATGGGCGAGGTCAACCGGCCCGTC
ACCGCGCTGCCGATGCGCAACGGCCGCCTGACGCTGAGCGAGGCGCTGTCGCAGGCCGGCAGCCTGAACGCGACGACGGC
CGACGCCGCGCAACTGTATGTGATTCGCGGCTCGCTCGACGCGAAGCCGCACGTGTATCGGCTCGACGCGAGCTCGCCCG
TCGCGATGGTGCTCGCGAACCAGTTCGAGCTGGAGCCGAAGGACATCGTCTATGTCGACGGCAACGGCCTCGTGCGCTTC
AGCCGCGTGCTCAGCCTGTTGCTGCCGGCCGTCAACGCCGGCCTGACCGCGGCGGTCGTGACCAAATGA

Upstream 100 bases:

>100_bases
TGTCGCTCGACGTGTCGTACGTGAAGGAATGGTCGCTTCGCCGCGACCTGGTCATCCTGTTGCAGACCGTCAACGTCGTC
CTGCGCGGATCGGGTGCGTA

Downstream 100 bases:

>100_bases
TCGAATCGGTTCTCATCGTCTGCGAGGGCAATCTCTGCCGCAGCCCGATGGCGGCCGCGCTCTTCGCGGCGGCGCTGCCG
GGGCGCGCGGTGACGTCGGC

Product: polysaccharide biosynthesis/export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MKPFVRRLRPEPAGTRKSIEVWMGSLGEAGGIAPPKRTCGARVRRLMKRVTLCAALAALSACGVAPGMRMKQPANVPVSS
AAADAPAEAGRKPRGEQLPVPITDIDLSLIRTLRDAQQAPRRAADLVSPASGYTIGRGDVLQITVWDHPELAAALGTQQQ
TAARAADAPAGFVVDQDGTLQYPYVGRIAVAGLKPEQVQARLARQLAQTFRDPQVTVRIASFRAKQVYIEGEVHTPGSQA
LNDIPMTLYDAVSRAGGFSASADQRRVTLVRDGVERRIDLSGAAQGVNPSRIVLRDGDLLRIPPRDESGVFVMGEVNRPV
TALPMRNGRLTLSEALSQAGSLNATTADAAQLYVIRGSLDAKPHVYRLDASSPVAMVLANQFELEPKDIVYVDGNGLVRF
SRVLSLLLPAVNAGLTAAVVTK

Sequences:

>Translated_422_residues
MKPFVRRLRPEPAGTRKSIEVWMGSLGEAGGIAPPKRTCGARVRRLMKRVTLCAALAALSACGVAPGMRMKQPANVPVSS
AAADAPAEAGRKPRGEQLPVPITDIDLSLIRTLRDAQQAPRRAADLVSPASGYTIGRGDVLQITVWDHPELAAALGTQQQ
TAARAADAPAGFVVDQDGTLQYPYVGRIAVAGLKPEQVQARLARQLAQTFRDPQVTVRIASFRAKQVYIEGEVHTPGSQA
LNDIPMTLYDAVSRAGGFSASADQRRVTLVRDGVERRIDLSGAAQGVNPSRIVLRDGDLLRIPPRDESGVFVMGEVNRPV
TALPMRNGRLTLSEALSQAGSLNATTADAAQLYVIRGSLDAKPHVYRLDASSPVAMVLANQFELEPKDIVYVDGNGLVRF
SRVLSLLLPAVNAGLTAAVVTK
>Mature_422_residues
MKPFVRRLRPEPAGTRKSIEVWMGSLGEAGGIAPPKRTCGARVRRLMKRVTLCAALAALSACGVAPGMRMKQPANVPVSS
AAADAPAEAGRKPRGEQLPVPITDIDLSLIRTLRDAQQAPRRAADLVSPASGYTIGRGDVLQITVWDHPELAAALGTQQQ
TAARAADAPAGFVVDQDGTLQYPYVGRIAVAGLKPEQVQARLARQLAQTFRDPQVTVRIASFRAKQVYIEGEVHTPGSQA
LNDIPMTLYDAVSRAGGFSASADQRRVTLVRDGVERRIDLSGAAQGVNPSRIVLRDGDLLRIPPRDESGVFVMGEVNRPV
TALPMRNGRLTLSEALSQAGSLNATTADAAQLYVIRGSLDAKPHVYRLDASSPVAMVLANQFELEPKDIVYVDGNGLVRF
SRVLSLLLPAVNAGLTAAVVTK

Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1787218, Length=377, Percent_Identity=36.0742705570292, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1788376, Length=375, Percent_Identity=34.9333333333333, Blast_Score=211, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715
- InterPro:   IPR019554 [H]

Pfam domain/function: PF02563 Poly_export; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 44979; Mature: 44979

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPFVRRLRPEPAGTRKSIEVWMGSLGEAGGIAPPKRTCGARVRRLMKRVTLCAALAALS
CCCHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ACGVAPGMRMKQPANVPVSSAAADAPAEAGRKPRGEQLPVPITDIDLSLIRTLRDAQQAP
HHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RRAADLVSPASGYTIGRGDVLQITVWDHPELAAALGTQQQTAARAADAPAGFVVDQDGTL
HHHHHHCCCCCCCEECCCCEEEEEECCCCHHHHHHCCCHHHHHHHCCCCCCEEECCCCCE
QYPYVGRIAVAGLKPEQVQARLARQLAQTFRDPQVTVRIASFRAKQVYIEGEVHTPGSQA
ECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECEEEEEEEEEECCCHHHH
LNDIPMTLYDAVSRAGGFSASADQRRVTLVRDGVERRIDLSGAAQGVNPSRIVLRDGDLL
HHCCCHHHHHHHHHCCCCCCCCCCCEEHHHHHCHHHEEECCCCCCCCCCCEEEEECCCEE
RIPPRDESGVFVMGEVNRPVTALPMRNGRLTLSEALSQAGSLNATTADAAQLYVIRGSLD
ECCCCCCCCEEEEEECCCCEEEEECCCCCEEHHHHHHHCCCCCCCCCCCEEEEEEECCCC
AKPHVYRLDASSPVAMVLANQFELEPKDIVYVDGNGLVRFSRVLSLLLPAVNAGLTAAVV
CCCEEEEECCCCCEEEEEEHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEE
TK
CC
>Mature Secondary Structure
MKPFVRRLRPEPAGTRKSIEVWMGSLGEAGGIAPPKRTCGARVRRLMKRVTLCAALAALS
CCCHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ACGVAPGMRMKQPANVPVSSAAADAPAEAGRKPRGEQLPVPITDIDLSLIRTLRDAQQAP
HHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RRAADLVSPASGYTIGRGDVLQITVWDHPELAAALGTQQQTAARAADAPAGFVVDQDGTL
HHHHHHCCCCCCCEECCCCEEEEEECCCCHHHHHHCCCHHHHHHHCCCCCCEEECCCCCE
QYPYVGRIAVAGLKPEQVQARLARQLAQTFRDPQVTVRIASFRAKQVYIEGEVHTPGSQA
ECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECEEEEEEEEEECCCHHHH
LNDIPMTLYDAVSRAGGFSASADQRRVTLVRDGVERRIDLSGAAQGVNPSRIVLRDGDLL
HHCCCHHHHHHHHHCCCCCCCCCCCEEHHHHHCHHHEEECCCCCCCCCCCEEEEECCCEE
RIPPRDESGVFVMGEVNRPVTALPMRNGRLTLSEALSQAGSLNATTADAAQLYVIRGSLD
ECCCCCCCCEEEEEECCCCEEEEECCCCCEEHHHHHHHCCCCCCCCCCCEEEEEEECCCC
AKPHVYRLDASSPVAMVLANQFELEPKDIVYVDGNGLVRFSRVLSLLLPAVNAGLTAAVV
CCCEEEEECCCCCEEEEEEHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEE
TK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]