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The map label for this gene is pepN [H]

Identifier: 237813353

GI number: 237813353

Start: 3030022

End: 3032724

Strand: Direct

Name: pepN [H]

Synonym: GBP346_A3123

Alternate gene names: 237813353

Gene position: 3030022-3032724 (Clockwise)

Preceding gene: 237813350

Following gene: 237813356

Centisome position: 73.93

GC content: 69.22

Gene sequence:

>2703_bases
ATGTCCGACATCGCCGCTCCCAACGCCGAGATCCGCCGCAGCGACTACACGCCGCCTGCGTTCCTGATCGATACCGTCTC
GCTCGAGTTCGATCTCGAGCCGGCGCGCACGATCGTCACGAACACGATGCGCGTGCGCCGCAACCCGGACGCCGCGCCCG
CACCGCACTTCGAGCTGATGGGCGAAGCGCTCGTGCTGATCGGCGCGCGCGTCGACGGCAAGCCGCACGACGCGGTGCGC
GTGCACGAACACGGCCTGAGCGTCGAGAACGTGCCCGATGCGTTCGAGCTGACGATCGAGAACGCATGCGCGCCCGAGTC
GAACACGACGCTGTCGGGCCTGTACGTATCGAGCGGCAACTTCTTCACGCAGTGCGAGGCGGAGGGCTTTCGGCGCATCA
CCTACTTCGTCGACCGTCCGGACGTGATGGCGTCGTACACGGTCACGCTGCGCGCCGACCAGGCCGCGTACCCGGTGCTG
CTGTCGAACGGCAATCTCGTCGACGCCGGCGATCTGCCGAACGGCCGTCACTTCGCGAAGTGGGAAGACCCGTTCAAGAA
GCCGAGCTACCTGTTCGCACTCGTCGCGGGCAAACTCGTCAAGCTCGAGGAAACGATCAAGTCGGCGAGCGGCAAGGACA
AGCTCCTGCAGGTGTGGGTCGAGCCGCAGGATCTCGGCAAGACCCGCCACGCGATGGATTCGCTGATCCATTCGATCCGC
TGGGACGAACGGCGCTTCGGCCTCGAGCTCGATCTCGACCGCTTCATGATCGTCGCCGTCGGCGATTTCAACATGGGCGC
GATGGAAAACAAGGGGCTCAACATCTTCAACACGAAGTACGTGCTCGCGAACCCGGAGACGGCGACCGACGTCGACTTCG
CGAACGTCGAATCGGTCGTCGGCCACGAGTATTTCCACAACTGGACGGGCAACCGCGTGACCTGCCGCGACTGGTTCCAG
TTGAGCCTGAAGGAAGGCCTCACCGTGTTCCGCGACCAGGAGTTCTCGGCGGACATGTCCGCGGGCGCCGAAGACGACGC
CGCCGCGCGCGCGGTCAAGCGCATCGAGGACGTGCGCGTGCTGCGCCAGCTCCAGTTCGCCGAGGACGCGGGCCCGATGG
CCCATCCGGTGCGGCCCGAGCGTTACGTCGAGATCAACAACTTCTACACGATGACCGTCTACGAGAAAGGCGCGGAAGTC
GTGCGGATGTACCAGACGCTGTTCGGCCGCGACGGTTTCCGCAAGGGGATGGACCTGTACTTCCGGCGCCACGACGGGCA
GGCCGTCACGTGCGACGACTTCCGCCACGCGATGGCCGACGCGAACGGCCGCGACCTCGCGCTGTTCGAGCGCTGGTACA
GCCAGGCGGGCACGCCGCGCGTGACGGTTCGCACCGCTTACGACGCCGCCGCGAAGCGCTACGCGGTGACGCTGCGGCAA
GGCTACGGCGACGCCGCGCCCGCCGCGCGCGACACGCAGAAAGGGCCGCTCCTGATCCCGTTCGCGATCGGCCTGATCGG
CGCCGACGGCCGCGATCTGCCGCTGCGCCTCGAAGGCGAAGCGGCCGCGTCGGGCACGACGCGCGTGCTCGAGCTGACCG
AGGCCGAGGCGACGTTCACGTTCGTCGACATCGACGCGGCGCCGCTGCCGTCGCTGCTGCGCAATTTCTCCGCGCCCGTG
ATCGTCGAATACGACTACCGCGACGACGAGCTCGCGTTCCTGCTCGCGCACGACAGCGATCCGTTCAACCGCTGGGAGGC
GGGCCAGCGCCTCGCGACGCGCGCGCTGCTCACGCTCGCGTCGCGTGCGGCGGCGCAGCAGCCGCTCACGCTCGACGACG
CGTTCGCCGCCGCGTTCAAGCGCGTGCTGACGGACGACACGCTGTCGCCCGCGTTCCGCGAGCTCGCGCTCACGTTGCCG
TCGGAGGCCTACCTCGCCGACCAGATGACGCAGGCCGATCCGGCCGCCGTCCATCGCGCGCGCCAGTTCGTGCGCCGCCA
GCTCGCGACGGCGCTACGCGCCGAGTGGCTCTCGGTCTACGAGCGCCACCAGACGCCGGGCGCGTATGCGCCGACGCCCG
GCGACGCGGGCCGCCGCGCGCTGAAGAACCTCGCGCTCGCCTACCTCGCCGAACTCGACGAGCCGGCCGACGCGATCCGG
CTCGCCACCGCGCAATACGACGCCGCGAACAACATGACCGACCGCGCGTGCGCGCTCGTCGCGCTGCTGTCGGCCGCCGC
CGCGTCGGCCGACGCGGCGCGCGCCGCCGATCGCGCGCTCGACGATTTCTATCGCCGCTTCGAGAACGAAGCGCTCGTGA
TCGACAAGTGGTTCTCGATGCAGGCGACGCGGCGCGGCACGCCCGAGCATCCGACGCTCGACATCGTGCGCAAGCTGCTC
GCGCATCCGGCGTTCAACCTGAAGAACCCGAACCGCGCACGCTCGCTGATCTTCGGCTTCTGCTCGGCGAATCCCGCGCA
GTTCCATGCGGCCGACGGCTCGGGCTACGCGTTCTGGGCCGATCAGGTGCTCGCGCTCGACGCGCTCAATCCGCAGGTCG
CCGCGCGGCTCGCGCGCGCGCTCGAGCTGTGGCGCCGCTTCACGCCGTCGCTGCGCGAGAAGATGCGCGACGCGCTCGAG
CGCGTCGCCGCGAACGCGCAGTCGCGCGACGTGCGGGAGATCGTCGAGAAGGCGCTCGCCTGA

Upstream 100 bases:

>100_bases
TCGTCGCGCGCGCCTTGCGCAAAGGCTTTGTACAATGGCCTTTTGCCGCCGCGCCGCCGCAGCGGCGCGTATTCACACTT
TTCCAACGCCCACGATCGCC

Downstream 100 bases:

>100_bases
CGGGTCCGGCGGACTCGACGGGCTCGACGCGCGATACGTTCGCCACCGCGCCGTTCGACGTTCGTGGCTGTCCCGGGACG
AAAAAGCCGGCATCGCGTCA

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 900; Mature: 899

Protein sequence:

>900_residues
MSDIAAPNAEIRRSDYTPPAFLIDTVSLEFDLEPARTIVTNTMRVRRNPDAAPAPHFELMGEALVLIGARVDGKPHDAVR
VHEHGLSVENVPDAFELTIENACAPESNTTLSGLYVSSGNFFTQCEAEGFRRITYFVDRPDVMASYTVTLRADQAAYPVL
LSNGNLVDAGDLPNGRHFAKWEDPFKKPSYLFALVAGKLVKLEETIKSASGKDKLLQVWVEPQDLGKTRHAMDSLIHSIR
WDERRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPETATDVDFANVESVVGHEYFHNWTGNRVTCRDWFQ
LSLKEGLTVFRDQEFSADMSAGAEDDAAARAVKRIEDVRVLRQLQFAEDAGPMAHPVRPERYVEINNFYTMTVYEKGAEV
VRMYQTLFGRDGFRKGMDLYFRRHDGQAVTCDDFRHAMADANGRDLALFERWYSQAGTPRVTVRTAYDAAAKRYAVTLRQ
GYGDAAPAARDTQKGPLLIPFAIGLIGADGRDLPLRLEGEAAASGTTRVLELTEAEATFTFVDIDAAPLPSLLRNFSAPV
IVEYDYRDDELAFLLAHDSDPFNRWEAGQRLATRALLTLASRAAAQQPLTLDDAFAAAFKRVLTDDTLSPAFRELALTLP
SEAYLADQMTQADPAAVHRARQFVRRQLATALRAEWLSVYERHQTPGAYAPTPGDAGRRALKNLALAYLAELDEPADAIR
LATAQYDAANNMTDRACALVALLSAAAASADAARAADRALDDFYRRFENEALVIDKWFSMQATRRGTPEHPTLDIVRKLL
AHPAFNLKNPNRARSLIFGFCSANPAQFHAADGSGYAFWADQVLALDALNPQVAARLARALELWRRFTPSLREKMRDALE
RVAANAQSRDVREIVEKALA

Sequences:

>Translated_900_residues
MSDIAAPNAEIRRSDYTPPAFLIDTVSLEFDLEPARTIVTNTMRVRRNPDAAPAPHFELMGEALVLIGARVDGKPHDAVR
VHEHGLSVENVPDAFELTIENACAPESNTTLSGLYVSSGNFFTQCEAEGFRRITYFVDRPDVMASYTVTLRADQAAYPVL
LSNGNLVDAGDLPNGRHFAKWEDPFKKPSYLFALVAGKLVKLEETIKSASGKDKLLQVWVEPQDLGKTRHAMDSLIHSIR
WDERRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPETATDVDFANVESVVGHEYFHNWTGNRVTCRDWFQ
LSLKEGLTVFRDQEFSADMSAGAEDDAAARAVKRIEDVRVLRQLQFAEDAGPMAHPVRPERYVEINNFYTMTVYEKGAEV
VRMYQTLFGRDGFRKGMDLYFRRHDGQAVTCDDFRHAMADANGRDLALFERWYSQAGTPRVTVRTAYDAAAKRYAVTLRQ
GYGDAAPAARDTQKGPLLIPFAIGLIGADGRDLPLRLEGEAAASGTTRVLELTEAEATFTFVDIDAAPLPSLLRNFSAPV
IVEYDYRDDELAFLLAHDSDPFNRWEAGQRLATRALLTLASRAAAQQPLTLDDAFAAAFKRVLTDDTLSPAFRELALTLP
SEAYLADQMTQADPAAVHRARQFVRRQLATALRAEWLSVYERHQTPGAYAPTPGDAGRRALKNLALAYLAELDEPADAIR
LATAQYDAANNMTDRACALVALLSAAAASADAARAADRALDDFYRRFENEALVIDKWFSMQATRRGTPEHPTLDIVRKLL
AHPAFNLKNPNRARSLIFGFCSANPAQFHAADGSGYAFWADQVLALDALNPQVAARLARALELWRRFTPSLREKMRDALE
RVAANAQSRDVREIVEKALA
>Mature_899_residues
SDIAAPNAEIRRSDYTPPAFLIDTVSLEFDLEPARTIVTNTMRVRRNPDAAPAPHFELMGEALVLIGARVDGKPHDAVRV
HEHGLSVENVPDAFELTIENACAPESNTTLSGLYVSSGNFFTQCEAEGFRRITYFVDRPDVMASYTVTLRADQAAYPVLL
SNGNLVDAGDLPNGRHFAKWEDPFKKPSYLFALVAGKLVKLEETIKSASGKDKLLQVWVEPQDLGKTRHAMDSLIHSIRW
DERRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPETATDVDFANVESVVGHEYFHNWTGNRVTCRDWFQL
SLKEGLTVFRDQEFSADMSAGAEDDAAARAVKRIEDVRVLRQLQFAEDAGPMAHPVRPERYVEINNFYTMTVYEKGAEVV
RMYQTLFGRDGFRKGMDLYFRRHDGQAVTCDDFRHAMADANGRDLALFERWYSQAGTPRVTVRTAYDAAAKRYAVTLRQG
YGDAAPAARDTQKGPLLIPFAIGLIGADGRDLPLRLEGEAAASGTTRVLELTEAEATFTFVDIDAAPLPSLLRNFSAPVI
VEYDYRDDELAFLLAHDSDPFNRWEAGQRLATRALLTLASRAAAQQPLTLDDAFAAAFKRVLTDDTLSPAFRELALTLPS
EAYLADQMTQADPAAVHRARQFVRRQLATALRAEWLSVYERHQTPGAYAPTPGDAGRRALKNLALAYLAELDEPADAIRL
ATAQYDAANNMTDRACALVALLSAAAASADAARAADRALDDFYRRFENEALVIDKWFSMQATRRGTPEHPTLDIVRKLLA
HPAFNLKNPNRARSLIFGFCSANPAQFHAADGSGYAFWADQVLALDALNPQVAARLARALELWRRFTPSLREKMRDALER
VAANAQSRDVREIVEKALA

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI61742777, Length=332, Percent_Identity=24.0963855421687, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI61742775, Length=332, Percent_Identity=24.0963855421687, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI158937236, Length=418, Percent_Identity=24.8803827751196, Blast_Score=110, Evalue=7e-24,
Organism=Homo sapiens, GI132814467, Length=348, Percent_Identity=24.4252873563218, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI157266300, Length=420, Percent_Identity=24.2857142857143, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI310123622, Length=375, Percent_Identity=24.8, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI310133497, Length=333, Percent_Identity=25.8258258258258, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI194306629, Length=305, Percent_Identity=23.6065573770492, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI11641261, Length=305, Percent_Identity=23.6065573770492, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI94818891, Length=323, Percent_Identity=24.1486068111455, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI94818901, Length=323, Percent_Identity=24.1486068111455, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI7019561, Length=339, Percent_Identity=24.4837758112094, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI40316915, Length=319, Percent_Identity=26.0188087774295, Blast_Score=70, Evalue=8e-12,
Organism=Escherichia coli, GI1787163, Length=890, Percent_Identity=47.8651685393258, Blast_Score=779, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989076, Length=399, Percent_Identity=26.0651629072682, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71989071, Length=399, Percent_Identity=26.0651629072682, Blast_Score=114, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI115533276, Length=329, Percent_Identity=25.8358662613982, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI115533278, Length=329, Percent_Identity=25.8358662613982, Blast_Score=100, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI193206928, Length=391, Percent_Identity=25.8312020460358, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17569225, Length=356, Percent_Identity=26.4044943820225, Blast_Score=98, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193206926, Length=391, Percent_Identity=25.8312020460358, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17569221, Length=370, Percent_Identity=25.1351351351351, Blast_Score=94, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI133903840, Length=449, Percent_Identity=22.71714922049, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71990873, Length=321, Percent_Identity=24.9221183800623, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71984339, Length=360, Percent_Identity=23.3333333333333, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71984353, Length=360, Percent_Identity=23.3333333333333, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17544504, Length=346, Percent_Identity=24.2774566473988, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI9755335, Length=402, Percent_Identity=26.865671641791, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321837, Length=407, Percent_Identity=25.0614250614251, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655257, Length=353, Percent_Identity=28.0453257790368, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24655252, Length=353, Percent_Identity=28.0453257790368, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24655274, Length=353, Percent_Identity=28.0453257790368, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24655260, Length=353, Percent_Identity=28.0453257790368, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24655265, Length=353, Percent_Identity=28.0453257790368, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24655268, Length=353, Percent_Identity=28.0453257790368, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24646514, Length=347, Percent_Identity=28.5302593659942, Blast_Score=117, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24646516, Length=347, Percent_Identity=28.5302593659942, Blast_Score=117, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24646518, Length=347, Percent_Identity=28.5302593659942, Blast_Score=116, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24651025, Length=380, Percent_Identity=25, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24651023, Length=380, Percent_Identity=25, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24651021, Length=380, Percent_Identity=25, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24648786, Length=397, Percent_Identity=26.7002518891688, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24646512, Length=349, Percent_Identity=23.7822349570201, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646510, Length=349, Percent_Identity=23.7822349570201, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI161078673, Length=388, Percent_Identity=26.2886597938144, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24651016, Length=207, Percent_Identity=29.4685990338164, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28571901, Length=388, Percent_Identity=26.2886597938144, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24650973, Length=361, Percent_Identity=26.3157894736842, Blast_Score=90, Evalue=6e-18,
Organism=Drosophila melanogaster, GI45550850, Length=361, Percent_Identity=26.3157894736842, Blast_Score=90, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21358341, Length=268, Percent_Identity=24.6268656716418, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI221379089, Length=349, Percent_Identity=24.6418338108883, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648790, Length=360, Percent_Identity=23.8888888888889, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571792, Length=371, Percent_Identity=24.5283018867925, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585062, Length=326, Percent_Identity=24.2331288343558, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24585064, Length=326, Percent_Identity=24.2331288343558, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24585066, Length=326, Percent_Identity=24.2331288343558, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45550350, Length=326, Percent_Identity=24.2331288343558, Blast_Score=72, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 100029; Mature: 99898

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIAAPNAEIRRSDYTPPAFLIDTVSLEFDLEPARTIVTNTMRVRRNPDAAPAPHFELM
CCCCCCCCCHHCCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHH
GEALVLIGARVDGKPHDAVRVHEHGLSVENVPDAFELTIENACAPESNTTLSGLYVSSGN
HCEEEEEEECCCCCCCCCEEEHHCCCCCCCCCCHHEEEECCCCCCCCCCEEEEEEEECCC
FFTQCEAEGFRRITYFVDRPDVMASYTVTLRADQAAYPVLLSNGNLVDAGDLPNGRHFAK
EEEEECCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCEEECCCCEEECCCCCCCCCCCC
WEDPFKKPSYLFALVAGKLVKLEETIKSASGKDKLLQVWVEPQDLGKTRHAMDSLIHSIR
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHCHHHHHHHHHHHHHC
WDERRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPETATDVDFANVESVV
CCHHHCCCEEECCEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHH
GHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMSAGAEDDAAARAVKRIEDVRV
HHHHHHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LRQLQFAEDAGPMAHPVRPERYVEINNFYTMTVYEKGAEVVRMYQTLFGRDGFRKGMDLY
HHHHHHHHCCCCCCCCCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHCCCCHHCCCCEE
FRRHDGQAVTCDDFRHAMADANGRDLALFERWYSQAGTPRVTVRTAYDAAAKRYAVTLRQ
EEECCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHEEEEEC
GYGDAAPAARDTQKGPLLIPFAIGLIGADGRDLPLRLEGEAAASGTTRVLELTEAEATFT
CCCCCCCCCCCCCCCCEEEEEEHEEECCCCCCCCEEECCCCCCCCCEEEEEEECCCEEEE
FVDIDAAPLPSLLRNFSAPVIVEYDYRDDELAFLLAHDSDPFNRWEAGQRLATRALLTLA
EEECCCCCHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
SRAAAQQPLTLDDAFAAAFKRVLTDDTLSPAFRELALTLPSEAYLADQMTQADPAAVHRA
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHH
RQFVRRQLATALRAEWLSVYERHQTPGAYAPTPGDAGRRALKNLALAYLAELDEPADAIR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHE
LATAQYDAANNMTDRACALVALLSAAAASADAARAADRALDDFYRRFENEALVIDKWFSM
EHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHH
QATRRGTPEHPTLDIVRKLLAHPAFNLKNPNRARSLIFGFCSANPAQFHAADGSGYAFWA
HHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHEEECCCCCCCEEEECCCCCEEEEC
DQVLALDALNPQVAARLARALELWRRFTPSLREKMRDALERVAANAQSRDVREIVEKALA
CHHHEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SDIAAPNAEIRRSDYTPPAFLIDTVSLEFDLEPARTIVTNTMRVRRNPDAAPAPHFELM
CCCCCCCCHHCCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHH
GEALVLIGARVDGKPHDAVRVHEHGLSVENVPDAFELTIENACAPESNTTLSGLYVSSGN
HCEEEEEEECCCCCCCCCEEEHHCCCCCCCCCCHHEEEECCCCCCCCCCEEEEEEEECCC
FFTQCEAEGFRRITYFVDRPDVMASYTVTLRADQAAYPVLLSNGNLVDAGDLPNGRHFAK
EEEEECCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCEEECCCCEEECCCCCCCCCCCC
WEDPFKKPSYLFALVAGKLVKLEETIKSASGKDKLLQVWVEPQDLGKTRHAMDSLIHSIR
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHCHHHHHHHHHHHHHC
WDERRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPETATDVDFANVESVV
CCHHHCCCEEECCEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHH
GHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMSAGAEDDAAARAVKRIEDVRV
HHHHHHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LRQLQFAEDAGPMAHPVRPERYVEINNFYTMTVYEKGAEVVRMYQTLFGRDGFRKGMDLY
HHHHHHHHCCCCCCCCCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHCCCCHHCCCCEE
FRRHDGQAVTCDDFRHAMADANGRDLALFERWYSQAGTPRVTVRTAYDAAAKRYAVTLRQ
EEECCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHEEEEEC
GYGDAAPAARDTQKGPLLIPFAIGLIGADGRDLPLRLEGEAAASGTTRVLELTEAEATFT
CCCCCCCCCCCCCCCCEEEEEEHEEECCCCCCCCEEECCCCCCCCCEEEEEEECCCEEEE
FVDIDAAPLPSLLRNFSAPVIVEYDYRDDELAFLLAHDSDPFNRWEAGQRLATRALLTLA
EEECCCCCHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
SRAAAQQPLTLDDAFAAAFKRVLTDDTLSPAFRELALTLPSEAYLADQMTQADPAAVHRA
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHH
RQFVRRQLATALRAEWLSVYERHQTPGAYAPTPGDAGRRALKNLALAYLAELDEPADAIR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHE
LATAQYDAANNMTDRACALVALLSAAAASADAARAADRALDDFYRRFENEALVIDKWFSM
EHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHH
QATRRGTPEHPTLDIVRKLLAHPAFNLKNPNRARSLIFGFCSANPAQFHAADGSGYAFWA
HHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHEEECCCCCCCEEEECCCCCEEEEC
DQVLALDALNPQVAARLARALELWRRFTPSLREKMRDALERVAANAQSRDVREIVEKALA
CHHHEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]