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The map label for this gene is aroA [H]

Identifier: 237813297

GI number: 237813297

Start: 2978224

End: 2980473

Strand: Reverse

Name: aroA [H]

Synonym: GBP346_A3064

Alternate gene names: 237813297

Gene position: 2980473-2978224 (Counterclockwise)

Preceding gene: 237813298

Following gene: 237813296

Centisome position: 72.72

GC content: 70.71

Gene sequence:

>2250_bases
GTGTCAGGCTTTTATTTCGACAAACTGGTGATTTTCGGCGTCGGGCTGATCGGCGGCTCGCTCGCGCTCGCGTTGCGCGA
AGGCGCGTCGGGCGGCCGGCGCGAGGTGGTGGGCGTCGGCCGCTCGTCGGCGTCGATCGGGCGCGCGCTCGCGTTGCGCG
TGATCGATCGCGCGGCGGCGCTCGACGACGATGCGCAACTGCGCGATGCGCTCGCGGGCGCGGACCTCGTGCTGCTCGCC
GCGCCCGTCGCTCAGACGGGCCCGCTGCTTGCGCGGATCGCGCCGTTTCTCGATGCATCGACGATCGTCACCGACGCGGG
CAGCACGAAATCGGACGTCGTCGCGGCCGCGCGCGCGGCGCTCGGCACGCGGATCGGCCAGTTCGTGCCGGGCCACCCGA
TCGCCGGGCGCGAATCGAGCGGCGTCGACGCGGCGCTCGCCGATCTGTACGTCGGCCGCAACGTCGTGCTATGCGCGCTG
CCGGAGAACGCGCCCGACGCGCTCGCGCGCGTCGAAGCGATGTGGCGCGCGGCGCGCGCCGACGTGCGCGCGATGAGCGC
CGAGCAGCACGACCGCGTGTTCGCGGCGGTGAGCCACCTGCCGCACGTGCTGTCGTTCGCGCTCGTCGAGCAGATTCTCG
GCGAATCCGACGCCGAGCTGAAGTTCTCGTATGCGGCGGGCGGTTTCCGCGATTTCACGCGCATCGCCGCGTCGAGCCCC
GAAATGTGGCGCGACGTCTGCCTCGCGAACCGCGCGGCGCTCCTCGACGAGCTCGACGCGTACACCGCGGTGCTCGCGCG
TCTGCGCGCGGCGATCGACGCGGGTGACGGCGCCGCGCTCGAGACCGTGTTCGCGCGCTCGCGCGCCGCGCGCGCCGCCT
GGCGCGAGCGCGGCGCGAAGCCCGCCCCCGCTGTCCGTTCAGACACTTCCGGAACAGGATCTCACATGGAACATCTCGAT
CTCGGCCCGTTCTCCCATGCGCAAGGCACGGTGCGCCTGCCCGGCTCGAAGAGCATTTCGAACCGCGTGCTGCTGCTCGC
GGCGCTCGCGGAGGGCGAGACGACCGTCACGAACCTGCTCGATTCCGACGATACGCGCGTGATGCTCGATGCGTTGACGA
AGCTCGGTGTGAAGCTGTCGCGCGACGGCGGCACCTGCGTCGTCGGCGGCACGCGCGGCGCGTTCACCGCGAAGACCGCC
GATCTCTTCCTCGGCAACGCGGGCACCGCGGTGCGGCCGCTGACGGCGGCGCTCGCGGTCAACGGCGGCGAGTACCGGAT
TCACGGGGTGCCGCGGATGCACGAGCGCCCGATCGGCGACCTCGTCGACGGGTTGCGCCAGATCGGCGCGCGGATCGACT
ACGAGGGCAACGAGGGCTTCCCGCCGCTCAGGATCCGGCCCGCGACGATTTCGGTCGACGCGCCGATCCGCGTGCGCGGC
GACGTGTCGAGCCAGTTCCTGACCGCGCTGCTGATGACGCTGCCGCTCGTGAAGGCGAAGGATGGCGCGAGCGTCGTCGA
GATCGACGGCGAGCTGATCTCTAAGCCGTACATCGAGATCACGATCAAGCTGATGGCGCGCTTCGGCGTGACGGTGGAGC
GCGACGGCTGGCAGCGCTTCACGGTGCCGGCGGGCGTGCGCTACCGGTCGCCCGGCACGATCATGGTCGAGGGCGACGCG
TCGTCGGCGTCGTATTTCCTCGCGGCGGGCGCGCTCGGCGGCGGGCCGCTGCGCGTCGAGGGCGTCGGCCGCGCGAGCAT
CCAGGGCGACGTCGGCTTCGCGAACGCGCTGATGCAGATGGGCGCGAACGTGACGATGGGCGACGACTGGATCGAGGTGC
GCGGCATCGGCCATGACCACGGCAGGCTCGCGCCGATCGACATGGACTTCAACCTGATTCCGGACGCCGCGATGACGATC
GCGGTCGTCGCGCTGTTCGCCGACGGCCCGAGCACGCTGCGCAACATCGGCAGCTGGCGCGTGAAGGAGACCGACCGGAT
CGCCGCGATGGCCACCGAGCTGCGCAAGGTCGGCGCGACGGTCGAAGAGGGTGCGGACTACCTCGTCGTGACTCCGCCCG
CGCAACTCACGCCGAATGCGTCGATCGATACCTACGACGATCACCGGATGGCGATGTGCTTTTCGCTCGTGAGCCTGGGC
GGCGTGCCCGTGCGCATCAACGATCCGAAGTGCGTCGGCAAGACGTTCCCCGACTATTTCGACCGTTTCCTCGCGCTCGC
GAACGCGTGA

Upstream 100 bases:

>100_bases
GCGCGCGCGTGCGCACGCGCGGCGCGCGGCGCGGGCGACCGTTCGATATTGACCTTGCGCGCCCGGGCTCTTCCGGGGCG
CGCGTTACTTGGCTCTCGTC

Downstream 100 bases:

>100_bases
CGCCCGTATTGACCCACCCGATGAAATCGACTCGACCTTTTCACCCGACCCCAGTTATTACGATCGACGGCCCGACGGCG
TCCGGCAAGGGCACCGTCGC

Product: bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 749; Mature: 748

Protein sequence:

>749_residues
MSGFYFDKLVIFGVGLIGGSLALALREGASGGRREVVGVGRSSASIGRALALRVIDRAAALDDDAQLRDALAGADLVLLA
APVAQTGPLLARIAPFLDASTIVTDAGSTKSDVVAAARAALGTRIGQFVPGHPIAGRESSGVDAALADLYVGRNVVLCAL
PENAPDALARVEAMWRAARADVRAMSAEQHDRVFAAVSHLPHVLSFALVEQILGESDAELKFSYAAGGFRDFTRIAASSP
EMWRDVCLANRAALLDELDAYTAVLARLRAAIDAGDGAALETVFARSRAARAAWRERGAKPAPAVRSDTSGTGSHMEHLD
LGPFSHAQGTVRLPGSKSISNRVLLLAALAEGETTVTNLLDSDDTRVMLDALTKLGVKLSRDGGTCVVGGTRGAFTAKTA
DLFLGNAGTAVRPLTAALAVNGGEYRIHGVPRMHERPIGDLVDGLRQIGARIDYEGNEGFPPLRIRPATISVDAPIRVRG
DVSSQFLTALLMTLPLVKAKDGASVVEIDGELISKPYIEITIKLMARFGVTVERDGWQRFTVPAGVRYRSPGTIMVEGDA
SSASYFLAAGALGGGPLRVEGVGRASIQGDVGFANALMQMGANVTMGDDWIEVRGIGHDHGRLAPIDMDFNLIPDAAMTI
AVVALFADGPSTLRNIGSWRVKETDRIAAMATELRKVGATVEEGADYLVVTPPAQLTPNASIDTYDDHRMAMCFSLVSLG
GVPVRINDPKCVGKTFPDYFDRFLALANA

Sequences:

>Translated_749_residues
MSGFYFDKLVIFGVGLIGGSLALALREGASGGRREVVGVGRSSASIGRALALRVIDRAAALDDDAQLRDALAGADLVLLA
APVAQTGPLLARIAPFLDASTIVTDAGSTKSDVVAAARAALGTRIGQFVPGHPIAGRESSGVDAALADLYVGRNVVLCAL
PENAPDALARVEAMWRAARADVRAMSAEQHDRVFAAVSHLPHVLSFALVEQILGESDAELKFSYAAGGFRDFTRIAASSP
EMWRDVCLANRAALLDELDAYTAVLARLRAAIDAGDGAALETVFARSRAARAAWRERGAKPAPAVRSDTSGTGSHMEHLD
LGPFSHAQGTVRLPGSKSISNRVLLLAALAEGETTVTNLLDSDDTRVMLDALTKLGVKLSRDGGTCVVGGTRGAFTAKTA
DLFLGNAGTAVRPLTAALAVNGGEYRIHGVPRMHERPIGDLVDGLRQIGARIDYEGNEGFPPLRIRPATISVDAPIRVRG
DVSSQFLTALLMTLPLVKAKDGASVVEIDGELISKPYIEITIKLMARFGVTVERDGWQRFTVPAGVRYRSPGTIMVEGDA
SSASYFLAAGALGGGPLRVEGVGRASIQGDVGFANALMQMGANVTMGDDWIEVRGIGHDHGRLAPIDMDFNLIPDAAMTI
AVVALFADGPSTLRNIGSWRVKETDRIAAMATELRKVGATVEEGADYLVVTPPAQLTPNASIDTYDDHRMAMCFSLVSLG
GVPVRINDPKCVGKTFPDYFDRFLALANA
>Mature_748_residues
SGFYFDKLVIFGVGLIGGSLALALREGASGGRREVVGVGRSSASIGRALALRVIDRAAALDDDAQLRDALAGADLVLLAA
PVAQTGPLLARIAPFLDASTIVTDAGSTKSDVVAAARAALGTRIGQFVPGHPIAGRESSGVDAALADLYVGRNVVLCALP
ENAPDALARVEAMWRAARADVRAMSAEQHDRVFAAVSHLPHVLSFALVEQILGESDAELKFSYAAGGFRDFTRIAASSPE
MWRDVCLANRAALLDELDAYTAVLARLRAAIDAGDGAALETVFARSRAARAAWRERGAKPAPAVRSDTSGTGSHMEHLDL
GPFSHAQGTVRLPGSKSISNRVLLLAALAEGETTVTNLLDSDDTRVMLDALTKLGVKLSRDGGTCVVGGTRGAFTAKTAD
LFLGNAGTAVRPLTAALAVNGGEYRIHGVPRMHERPIGDLVDGLRQIGARIDYEGNEGFPPLRIRPATISVDAPIRVRGD
VSSQFLTALLMTLPLVKAKDGASVVEIDGELISKPYIEITIKLMARFGVTVERDGWQRFTVPAGVRYRSPGTIMVEGDAS
SASYFLAAGALGGGPLRVEGVGRASIQGDVGFANALMQMGANVTMGDDWIEVRGIGHDHGRLAPIDMDFNLIPDAAMTIA
VVALFADGPSTLRNIGSWRVKETDRIAAMATELRKVGATVEEGADYLVVTPPAQLTPNASIDTYDDHRMAMCFSLVSLGG
VPVRINDPKCVGKTFPDYFDRFLALANA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=437, Percent_Identity=57.4370709382151, Blast_Score=458, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6320332, Length=455, Percent_Identity=38.2417582417582, Blast_Score=243, Evalue=8e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 78866; Mature: 78735

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGFYFDKLVIFGVGLIGGSLALALREGASGGRREVVGVGRSSASIGRALALRVIDRAAA
CCCHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHC
LDDDAQLRDALAGADLVLLAAPVAQTGPLLARIAPFLDASTIVTDAGSTKSDVVAAARAA
CCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHH
LGTRIGQFVPGHPIAGRESSGVDAALADLYVGRNVVLCALPENAPDALARVEAMWRAARA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
DVRAMSAEQHDRVFAAVSHLPHVLSFALVEQILGESDAELKFSYAAGGFRDFTRIAASSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCH
EMWRDVCLANRAALLDELDAYTAVLARLRAAIDAGDGAALETVFARSRAARAAWRERGAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
PAPAVRSDTSGTGSHMEHLDLGPFSHAQGTVRLPGSKSISNRVLLLAALAEGETTVTNLL
CCCCCCCCCCCCCCCCHHCCCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCCHHHHHHH
DSDDTRVMLDALTKLGVKLSRDGGTCVVGGTRGAFTAKTADLFLGNAGTAVRPLTAALAV
CCCCCCHHHHHHHHCCEEEECCCCEEEECCCCCCCEEEEHHEEECCCCCCHHHHEEEEEE
NGGEYRIHGVPRMHERPIGDLVDGLRQIGARIDYEGNEGFPPLRIRPATISVDAPIRVRG
CCCCEEEECCCCHHCCCHHHHHHHHHHHCCEEECCCCCCCCCEEEEEEEEEECCCEEEEC
DVSSQFLTALLMTLPLVKAKDGASVVEIDGELISKPYIEITIKLMARFGVTVERDGWQRF
CCHHHHHHHHHHHHCCEECCCCCEEEEECHHHHCCCHHHHHHHHHHHHCCEEECCCCEEE
TVPAGVRYRSPGTIMVEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFANALMQM
ECCCCEEECCCCEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHC
GANVTMGDDWIEVRGIGHDHGRLAPIDMDFNLIPDAAMTIAVVALFADGPSTLRNIGSWR
CCCCEECCCEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCE
VKETDRIAAMATELRKVGATVEEGADYLVVTPPAQLTPNASIDTYDDHRMAMCFSLVSLG
ECCHHHHHHHHHHHHHHCCHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
GVPVRINDPKCVGKTFPDYFDRFLALANA
CEEEEECCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SGFYFDKLVIFGVGLIGGSLALALREGASGGRREVVGVGRSSASIGRALALRVIDRAAA
CCHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHC
LDDDAQLRDALAGADLVLLAAPVAQTGPLLARIAPFLDASTIVTDAGSTKSDVVAAARAA
CCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHH
LGTRIGQFVPGHPIAGRESSGVDAALADLYVGRNVVLCALPENAPDALARVEAMWRAARA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
DVRAMSAEQHDRVFAAVSHLPHVLSFALVEQILGESDAELKFSYAAGGFRDFTRIAASSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCH
EMWRDVCLANRAALLDELDAYTAVLARLRAAIDAGDGAALETVFARSRAARAAWRERGAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
PAPAVRSDTSGTGSHMEHLDLGPFSHAQGTVRLPGSKSISNRVLLLAALAEGETTVTNLL
CCCCCCCCCCCCCCCCHHCCCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCCHHHHHHH
DSDDTRVMLDALTKLGVKLSRDGGTCVVGGTRGAFTAKTADLFLGNAGTAVRPLTAALAV
CCCCCCHHHHHHHHCCEEEECCCCEEEECCCCCCCEEEEHHEEECCCCCCHHHHEEEEEE
NGGEYRIHGVPRMHERPIGDLVDGLRQIGARIDYEGNEGFPPLRIRPATISVDAPIRVRG
CCCCEEEECCCCHHCCCHHHHHHHHHHHCCEEECCCCCCCCCEEEEEEEEEECCCEEEEC
DVSSQFLTALLMTLPLVKAKDGASVVEIDGELISKPYIEITIKLMARFGVTVERDGWQRF
CCHHHHHHHHHHHHCCEECCCCCEEEEECHHHHCCCHHHHHHHHHHHHCCEEECCCCEEE
TVPAGVRYRSPGTIMVEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFANALMQM
ECCCCEEECCCCEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHC
GANVTMGDDWIEVRGIGHDHGRLAPIDMDFNLIPDAAMTIAVVALFADGPSTLRNIGSWR
CCCCEECCCEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCE
VKETDRIAAMATELRKVGATVEEGADYLVVTPPAQLTPNASIDTYDDHRMAMCFSLVSLG
ECCHHHHHHHHHHHHHHCCHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
GVPVRINDPKCVGKTFPDYFDRFLALANA
CEEEEECCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA