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The map label for this gene is udg [H]

Identifier: 237813291

GI number: 237813291

Start: 2972053

End: 2973453

Strand: Reverse

Name: udg [H]

Synonym: GBP346_A3058

Alternate gene names: 237813291

Gene position: 2973453-2972053 (Counterclockwise)

Preceding gene: 237813292

Following gene: 237813290

Centisome position: 72.55

GC content: 66.1

Gene sequence:

>1401_bases
ATGAAGATCACCATCATCGGCACGGGTTATGTGGGCCTCGTCACCGGCGCGTGTCTCGCCGAGATCGGCCACGACGTGTT
CTGTCTCGACGTCGATCCCCGCAAGATCGACATCCTGAACAACGGCGGCATGCCGATTCACGAGCCGGGTCTGCAGGAAA
TCATCGCGCGCACGCGCGCCGCCGGCCGCATCGCGTTCTCGACGGACATCGAGGCGAGCGTCGCGCACGGCGAGATTCAA
TTCATCGCGGTCGGCACGCCGCCCGACGAGGACGGCTCGGCGGACCTGCAATACGTGCTCGAGGCCGCGCGCAACATCGG
CCGCCACATGACGGGCTACAAGGTGATCGTCGACAAATCGACGGTGCCTGTCGGCACCGCGCAGCGCGTGCGCGCGGTGA
TCGACGAGGCGCTTGCCGCGCGCGGCCTCGCGGGCAGCGCAGAGCATCGCTTCTCGGTCGTGTCGAATCCCGAGTTCCTG
AAAGAGGGCGCGGCCGTCGACGATTTCATGCGGCCGGACCGGATCATCATCGGCGTCGACGACGACGCGGCGGGCGCGAT
CGCCCGCGAGAAGATGAAGAAGCTCTACGCGCCGTTCAACCGCAATCACGAGCGCACGATCTACATGGACGTGCGCTCGG
CGGAGTTCTCGAAATACGCGGCGAACGCGATGCTCGCGACGCGCATCTCGTTCATGAACGAGATGTCGAATCTCGCGGAT
CGCGTCGGCGCCGACATCGAGGCGGTGCGCCGCGGGATCGGCTCCGATCCGCGGATCGGCTATCACTTCCTGTATGCGGG
CGTCGGCTACGGCGGCTCGTGCTTTCCGAAGGACGTGCAGGCGCTCATTCGCACCGCGAGCGAAAACGGTCAGCCGCTCA
GGATTCTCGAGGCGGTCGAGGACGTGAACCACGCACAGAAGAACGTGCTGCTCGACAAGATCGAAAAGCGCTACGGCGCC
GATCTGGCGGGCCGCACGTTCGCTGTCTGGGGGCTCGCGTTCAAGCCGAACACCGACGACATGCGCGAAGCGCCGAGCCG
ACGCCTGATCGCTTCGCTGCTCGCGCGCGGCGCGACGGTGCGCGCGTACGATCCCGTCGCGCTCGACGAGGCGCGGCGCG
TGTTCGCGCTCGATCTGCACGACGGGGCCGATGCGCTCGCGCGTCTCGCATTCGTCGATTCGGCCGACGACGCGCTCGCG
GGCGCGGACGCGCTCGTCATCGTCACCGAATGGAAGGAATTCAAGAGCCCGGACTTCGCGCATCTGAAATCGGTGCTGAA
GGCGCCCGTGATCTTCGACGGCCGCAACCTGTATGAACCCGACGCGATGGCCGAGCTCGGCATCGATTACCACGCCATTG
GACGCCCCTATGTCGAGCCCTTCTCTTCCGAGCGCGGATAA

Upstream 100 bases:

>100_bases
AATGAAGCGGTAATGAGGCAGGCCTCGCGGGCCGGCGCGACGCCGCCCGCGGCCTGAGCCGGGCGGACGCCGTTCGCCCG
AGAGAATCATCGGAATACTT

Downstream 100 bases:

>100_bases
GCGCGCATCGCTTGCCGCGACCGCGCGCGCGGTGTCGCGCGAGCAGATCGCGAAGTCGCGCGTGCTTGTCGTCGGCGACG
TGATGCTCGATCGTTACTGG

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLQEIIARTRAAGRIAFSTDIEASVAHGEIQ
FIAVGTPPDEDGSADLQYVLEAARNIGRHMTGYKVIVDKSTVPVGTAQRVRAVIDEALAARGLAGSAEHRFSVVSNPEFL
KEGAAVDDFMRPDRIIIGVDDDAAGAIAREKMKKLYAPFNRNHERTIYMDVRSAEFSKYAANAMLATRISFMNEMSNLAD
RVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTASENGQPLRILEAVEDVNHAQKNVLLDKIEKRYGA
DLAGRTFAVWGLAFKPNTDDMREAPSRRLIASLLARGATVRAYDPVALDEARRVFALDLHDGADALARLAFVDSADDALA
GADALVIVTEWKEFKSPDFAHLKSVLKAPVIFDGRNLYEPDAMAELGIDYHAIGRPYVEPFSSERG

Sequences:

>Translated_466_residues
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLQEIIARTRAAGRIAFSTDIEASVAHGEIQ
FIAVGTPPDEDGSADLQYVLEAARNIGRHMTGYKVIVDKSTVPVGTAQRVRAVIDEALAARGLAGSAEHRFSVVSNPEFL
KEGAAVDDFMRPDRIIIGVDDDAAGAIAREKMKKLYAPFNRNHERTIYMDVRSAEFSKYAANAMLATRISFMNEMSNLAD
RVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTASENGQPLRILEAVEDVNHAQKNVLLDKIEKRYGA
DLAGRTFAVWGLAFKPNTDDMREAPSRRLIASLLARGATVRAYDPVALDEARRVFALDLHDGADALARLAFVDSADDALA
GADALVIVTEWKEFKSPDFAHLKSVLKAPVIFDGRNLYEPDAMAELGIDYHAIGRPYVEPFSSERG
>Mature_466_residues
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLQEIIARTRAAGRIAFSTDIEASVAHGEIQ
FIAVGTPPDEDGSADLQYVLEAARNIGRHMTGYKVIVDKSTVPVGTAQRVRAVIDEALAARGLAGSAEHRFSVVSNPEFL
KEGAAVDDFMRPDRIIIGVDDDAAGAIAREKMKKLYAPFNRNHERTIYMDVRSAEFSKYAANAMLATRISFMNEMSNLAD
RVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTASENGQPLRILEAVEDVNHAQKNVLLDKIEKRYGA
DLAGRTFAVWGLAFKPNTDDMREAPSRRLIASLLARGATVRAYDPVALDEARRVFALDLHDGADALARLAFVDSADDALA
GADALVIVTEWKEFKSPDFAHLKSVLKAPVIFDGRNLYEPDAMAELGIDYHAIGRPYVEPFSSERG

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=472, Percent_Identity=36.0169491525424, Blast_Score=258, Evalue=8e-69,
Organism=Homo sapiens, GI296040438, Length=374, Percent_Identity=36.6310160427808, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI296040443, Length=315, Percent_Identity=37.7777777777778, Blast_Score=178, Evalue=1e-44,
Organism=Escherichia coli, GI1788340, Length=380, Percent_Identity=29.4736842105263, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI48994968, Length=438, Percent_Identity=26.7123287671233, Blast_Score=139, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17560350, Length=469, Percent_Identity=35.8208955223881, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI17136908, Length=472, Percent_Identity=34.9576271186441, Blast_Score=255, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 50659; Mature: 50659

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLQEIIARTRA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHH
AGRIAFSTDIEASVAHGEIQFIAVGTPPDEDGSADLQYVLEAARNIGRHMTGYKVIVDKS
CCEEEEECCCCCEEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
TVPVGTAQRVRAVIDEALAARGLAGSAEHRFSVVSNPEFLKEGAAVDDFMRPDRIIIGVD
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHCCCCHHHHCCCCEEEEECC
DDAAGAIAREKMKKLYAPFNRNHERTIYMDVRSAEFSKYAANAMLATRISFMNEMSNLAD
CCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTASENGQPLRILEAVE
HHCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
DVNHAQKNVLLDKIEKRYGADLAGRTFAVWGLAFKPNTDDMREAPSRRLIASLLARGATV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCHHHHHHHHHHHCCCEE
RAYDPVALDEARRVFALDLHDGADALARLAFVDSADDALAGADALVIVTEWKEFKSPDFA
EECCCHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCHHHCCCCEEEEEEECHHHCCCCHH
HLKSVLKAPVIFDGRNLYEPDAMAELGIDYHAIGRPYVEPFSSERG
HHHHHHCCCEEECCCCCCCCHHHHHHCCCHHHCCCCHHCCCCCCCC
>Mature Secondary Structure
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLQEIIARTRA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHH
AGRIAFSTDIEASVAHGEIQFIAVGTPPDEDGSADLQYVLEAARNIGRHMTGYKVIVDKS
CCEEEEECCCCCEEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
TVPVGTAQRVRAVIDEALAARGLAGSAEHRFSVVSNPEFLKEGAAVDDFMRPDRIIIGVD
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHCCCCHHHHCCCCEEEEECC
DDAAGAIAREKMKKLYAPFNRNHERTIYMDVRSAEFSKYAANAMLATRISFMNEMSNLAD
CCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTASENGQPLRILEAVE
HHCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
DVNHAQKNVLLDKIEKRYGADLAGRTFAVWGLAFKPNTDDMREAPSRRLIASLLARGATV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCHHHHHHHHHHHCCCEE
RAYDPVALDEARRVFALDLHDGADALARLAFVDSADDALAGADALVIVTEWKEFKSPDFA
EECCCHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCHHHCCCCEEEEEEECHHHCCCCHH
HLKSVLKAPVIFDGRNLYEPDAMAELGIDYHAIGRPYVEPFSSERG
HHHHHHCCCEEECCCCCCCCHHHHHHCCCHHHCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]