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The map label for this gene is otsB [H]

Identifier: 237813173

GI number: 237813173

Start: 2863690

End: 2864442

Strand: Reverse

Name: otsB [H]

Synonym: GBP346_A2935

Alternate gene names: 237813173

Gene position: 2864442-2863690 (Counterclockwise)

Preceding gene: 237813175

Following gene: 237813172

Centisome position: 69.89

GC content: 71.98

Gene sequence:

>753_bases
ATGCAATCCATCCCGCTTTCCCTGCCCCTTGCCCGCACCGCGTTCTTCTTCGATTTCGACGGCACGCTCGTCGACCTCGC
GCCGACGCCCGACGCCATCCAGGTGCCGCCCGACGTGCCCGTGCTCGTCGACGCGCTGCGGCAACTGTCGCACGGCGCGG
TCGCGATCGTGTCCGGGCGCGGCATCGACAGCATCGACGCATACCTCAACCTGCCCGGCCTGCCGGTGGCGGGCCTGCAC
GGCGCCGAGCGGCGCGACGCGAACGGCGACACGCAGCGGATCGGCTTCGACGATCCGCGGCTGCTGCGTATCGAGCGCGA
ACTCGCGGCGCTCGTCGATCGCCACCCGGGCATGCTGCTCGAGATCAAGGGCGCGGCGCTCGCGCTGCATTTTCGCAACG
CGCCCGAACGCGAGGGCGTCGCGCGCGCGGCGGCCGAGCGGCTCGTCGCCGATTACGCGGATGCGTACGTGCTGCAGCCG
GGCAAGATGGTGTTCGAGATCAAGCCGAAGGGCGTCGACAAGGGGCGCGCGGTTGCCGCGTTCCTGAACGAGCCGCCGTT
CGCCGGCCGCATGCCGGTGTTCGCCGGCGACGATCTGACCGACGAGCAGGGCTTCGCCGTCGCCAACGCGAACGGCGGAT
TGTCGATCAAGGTCGGTGCGGGCGACACGACGGCGCGCGCGCGCGTCGATTCGGTCGCCGCGTTGCGCGCGCAGCTCGCG
CGCTGGATCGCCGCGGGGCGCGCGCCCGCATGA

Upstream 100 bases:

>100_bases
GCGGGGCCCGCGCTTTTGTTCATCGTGCACGAGGCGCGGTAAGATGCGCACATTCGCCCGGCGGGCGCGCCCGCCGGCAG
CCATTCTCTTCAGCGAATCG

Downstream 100 bases:

>100_bases
GCCGTCTCATCATCGTCTCGAATCGGGTCGCGCCGATCTCCGAAGGAGAACCCGCGGCCGGCGGCCTCGCGATCGGCGTC
TACGACGCGCTGAAGGAAAC

Product: trehalose-phosphatase

Products: NA

Alternate protein names: TPP; Trehalose 6-phosphate phosphatase; Trehalose-phosphatase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MQSIPLSLPLARTAFFFDFDGTLVDLAPTPDAIQVPPDVPVLVDALRQLSHGAVAIVSGRGIDSIDAYLNLPGLPVAGLH
GAERRDANGDTQRIGFDDPRLLRIERELAALVDRHPGMLLEIKGAALALHFRNAPEREGVARAAAERLVADYADAYVLQP
GKMVFEIKPKGVDKGRAVAAFLNEPPFAGRMPVFAGDDLTDEQGFAVANANGGLSIKVGAGDTTARARVDSVAALRAQLA
RWIAAGRAPA

Sequences:

>Translated_250_residues
MQSIPLSLPLARTAFFFDFDGTLVDLAPTPDAIQVPPDVPVLVDALRQLSHGAVAIVSGRGIDSIDAYLNLPGLPVAGLH
GAERRDANGDTQRIGFDDPRLLRIERELAALVDRHPGMLLEIKGAALALHFRNAPEREGVARAAAERLVADYADAYVLQP
GKMVFEIKPKGVDKGRAVAAFLNEPPFAGRMPVFAGDDLTDEQGFAVANANGGLSIKVGAGDTTARARVDSVAALRAQLA
RWIAAGRAPA
>Mature_250_residues
MQSIPLSLPLARTAFFFDFDGTLVDLAPTPDAIQVPPDVPVLVDALRQLSHGAVAIVSGRGIDSIDAYLNLPGLPVAGLH
GAERRDANGDTQRIGFDDPRLLRIERELAALVDRHPGMLLEIKGAALALHFRNAPEREGVARAAAERLVADYADAYVLQP
GKMVFEIKPKGVDKGRAVAAFLNEPPFAGRMPVFAGDDLTDEQGFAVANANGGLSIKVGAGDTTARARVDSVAALRAQLA
RWIAAGRAPA

Specific function: Removes the phosphate from trehalose 6-phosphate to produce free trehalose [H]

COG id: COG1877

COG function: function code G; Trehalose-6-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trehalose phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788207, Length=222, Percent_Identity=45.945945945946, Blast_Score=194, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6320279, Length=226, Percent_Identity=27.8761061946903, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920676, Length=247, Percent_Identity=28.7449392712551, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221473368, Length=246, Percent_Identity=25.609756097561, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129307, Length=246, Percent_Identity=25.609756097561, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582490, Length=246, Percent_Identity=25.609756097561, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR003337 [H]

Pfam domain/function: PF02358 Trehalose_PPase [H]

EC number: =3.1.3.12 [H]

Molecular weight: Translated: 26442; Mature: 26442

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSIPLSLPLARTAFFFDFDGTLVDLAPTPDAIQVPPDVPVLVDALRQLSHGAVAIVSGR
CCCCCCCCCCEEEEEEEECCCEEEEECCCCCCEECCCCCHHHHHHHHHHCCCEEEEEECC
GIDSIDAYLNLPGLPVAGLHGAERRDANGDTQRIGFDDPRLLRIERELAALVDRHPGMLL
CCCCHHHEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEHHHHHHHHHHCCCCEEE
EIKGAALALHFRNAPEREGVARAAAERLVADYADAYVLQPGKMVFEIKPKGVDKGRAVAA
EECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEECCCCEEEEECCCCCCCCCEEEE
FLNEPPFAGRMPVFAGDDLTDEQGFAVANANGGLSIKVGAGDTTARARVDSVAALRAQLA
ECCCCCCCCCCCEEECCCCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
RWIAAGRAPA
HHHHCCCCCC
>Mature Secondary Structure
MQSIPLSLPLARTAFFFDFDGTLVDLAPTPDAIQVPPDVPVLVDALRQLSHGAVAIVSGR
CCCCCCCCCCEEEEEEEECCCEEEEECCCCCCEECCCCCHHHHHHHHHHCCCEEEEEECC
GIDSIDAYLNLPGLPVAGLHGAERRDANGDTQRIGFDDPRLLRIERELAALVDRHPGMLL
CCCCHHHEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEHHHHHHHHHHCCCCEEE
EIKGAALALHFRNAPEREGVARAAAERLVADYADAYVLQPGKMVFEIKPKGVDKGRAVAA
EECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEECCCCEEEEECCCCCCCCCEEEE
FLNEPPFAGRMPVFAGDDLTDEQGFAVANANGGLSIKVGAGDTTARARVDSVAALRAQLA
ECCCCCCCCCCCEEECCCCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
RWIAAGRAPA
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]