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The map label for this gene is dinB [H]

Identifier: 237813039

GI number: 237813039

Start: 2730353

End: 2731573

Strand: Reverse

Name: dinB [H]

Synonym: GBP346_A2799

Alternate gene names: 237813039

Gene position: 2731573-2730353 (Counterclockwise)

Preceding gene: 237813043

Following gene: 237813037

Centisome position: 66.65

GC content: 70.52

Gene sequence:

>1221_bases
ATGCCCCCCTCCGACCCGCCTCCGCCGCCCTCGGGCGACGCGGCGCACCTCGCGCGCAAGATCATCCATTGCGACTGCGA
CTGTTTCTACGCGTCGGTCGAGATGCGCGACGATCCGTCGCTGCGCGGCCGTCCGCTCGCGGTCGGCGGCCGTCCCGACC
AGCGCGGCGTGATCGCGACCTGCAACTACGACGCGCGCCGCTACGGCGTGCATTCGGCGATGTCGTCGGCGCTCGCGATG
CGCAAGTGTCCGGATCTGCTGATCCTGCCGCCCGCGATGGACAAGTACCGCGCGGCGTCGCGGCTCATCATGGCGATCTA
TCGCGACTACACGCCCGACGTCGAGCCGCTGTCGCTCGACGAGGCGTATCTCGACGTGAGCCGCGCGACGCGCTGCCAGG
GCAGCGGCACGCTGATCGCGCGCGAGATTCGCGAGCGCGTGCGCGATACGGTGGGCGTCACGGTGTCGGCGGGCGTCGCG
CCGAACAAGTTCATCGCGAAGATCGCGTCCGACTGGAACAAGCCCGACGGCCTGTTCGTCGTGCGTCCGCACGAAGTCGA
CGCGTTCGTCGCCGCGCTGCCCGTGCGCAAGCTGCACGGCGTCGGCAAGGTGACGGCGGCGCGTCTCGACAAGCTCGGCA
TCCGTACCTGCGCGCAATTGCGCGACTGGTCGCTGTTCGATCTGCATCGCACGTTCGGCGCGTTCGGCAGACGGCTCCAC
GAGCTCGCGCGCGGCATCGACGAGCGGCCGGTGCGCGCGGACCAGGCGCGCAAGTCGGTGAGCGTCGAGACGACCTACGT
GCAGGACCTCGCGGCGCTCGACGCGTGCGCGGCCGAGATCCGGCGGCTGACCGGGCTGCTCGACGCGCGGATCGAACGGG
CGGGAGCCGCGCGCTCGATCAGGAAGCTGTACGTGAAGATCCGCTTCGCGGATTTCCAGCGCACGACGGTCGAATGCGTC
GCCGACGCGACCGATGCCGAGACCGCGGTCGCGCTGCTCGCGAAAGGGCTCGCGCGCCGCAGGCAGGCGGTGCGGCTGTT
GGGCGTCGGCGTGCGGATCGACGAGGACACGGCCGAGCGGCACGGACAGATCGCGCTCTTCGACGACGAGGACATGAGCG
ACGAAGATGCCGAAGGCGACGAAGGCGACGAAGGCGGTGAAGTCGGCGAGGACGGCGAGGACGGCGAGGGTGACGAAGGC
GATGCGTCGCCCGGCGCATGA

Upstream 100 bases:

>100_bases
GCAATCGCCTCAATCGCCTCAATCGCCGCGCACGGCGGCGCACTGTGCAGTTGAAACGCGCACTGTGTCTTTGTACAGTA
TCGGCACCTTGGACAAGCCG

Downstream 100 bases:

>100_bases
TCGAACGCGCGGCCGCGCGCGGCCTTGATGGCGCGATGAAAAAACGGCAACCCGCCGATGCGGGTTGCCGTTCGTCGTTG
CGCGGAGCCGGCGGGCGAGG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MPPSDPPPPPSGDAAHLARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRGVIATCNYDARRYGVHSAMSSALAM
RKCPDLLILPPAMDKYRAASRLIMAIYRDYTPDVEPLSLDEAYLDVSRATRCQGSGTLIAREIRERVRDTVGVTVSAGVA
PNKFIAKIASDWNKPDGLFVVRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCAQLRDWSLFDLHRTFGAFGRRLH
ELARGIDERPVRADQARKSVSVETTYVQDLAALDACAAEIRRLTGLLDARIERAGAARSIRKLYVKIRFADFQRTTVECV
ADATDAETAVALLAKGLARRRQAVRLLGVGVRIDEDTAERHGQIALFDDEDMSDEDAEGDEGDEGGEVGEDGEDGEGDEG
DASPGA

Sequences:

>Translated_406_residues
MPPSDPPPPPSGDAAHLARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRGVIATCNYDARRYGVHSAMSSALAM
RKCPDLLILPPAMDKYRAASRLIMAIYRDYTPDVEPLSLDEAYLDVSRATRCQGSGTLIAREIRERVRDTVGVTVSAGVA
PNKFIAKIASDWNKPDGLFVVRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCAQLRDWSLFDLHRTFGAFGRRLH
ELARGIDERPVRADQARKSVSVETTYVQDLAALDACAAEIRRLTGLLDARIERAGAARSIRKLYVKIRFADFQRTTVECV
ADATDAETAVALLAKGLARRRQAVRLLGVGVRIDEDTAERHGQIALFDDEDMSDEDAEGDEGDEGGEVGEDGEDGEGDEG
DASPGA
>Mature_405_residues
PPSDPPPPPSGDAAHLARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRGVIATCNYDARRYGVHSAMSSALAMR
KCPDLLILPPAMDKYRAASRLIMAIYRDYTPDVEPLSLDEAYLDVSRATRCQGSGTLIAREIRERVRDTVGVTVSAGVAP
NKFIAKIASDWNKPDGLFVVRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCAQLRDWSLFDLHRTFGAFGRRLHE
LARGIDERPVRADQARKSVSVETTYVQDLAALDACAAEIRRLTGLLDARIERAGAARSIRKLYVKIRFADFQRTTVECVA
DATDAETAVALLAKGLARRRQAVRLLGVGVRIDEDTAERHGQIALFDDEDMSDEDAEGDEGDEGGEVGEDGEDGEGDEGD
ASPGA

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=341, Percent_Identity=27.8592375366569, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI7706681, Length=342, Percent_Identity=27.7777777777778, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI154350220, Length=325, Percent_Identity=28.9230769230769, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI7705344, Length=113, Percent_Identity=47.787610619469, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI5729982, Length=367, Percent_Identity=26.7029972752044, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1786425, Length=350, Percent_Identity=47.4285714285714, Blast_Score=311, Evalue=3e-86,
Organism=Escherichia coli, GI1787432, Length=231, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193205700, Length=436, Percent_Identity=27.5229357798165, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17537959, Length=291, Percent_Identity=29.8969072164948, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193205702, Length=379, Percent_Identity=25.3298153034301, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI115534089, Length=127, Percent_Identity=38.5826771653543, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324921, Length=206, Percent_Identity=28.1553398058252, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19923006, Length=346, Percent_Identity=26.878612716763, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21355641, Length=290, Percent_Identity=30.3448275862069, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24644984, Length=290, Percent_Identity=30.3448275862069, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24668444, Length=287, Percent_Identity=23.6933797909408, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 44234; Mature: 44103

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPSDPPPPPSGDAAHLARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRGVIAT
CCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCCEEEE
CNYDARRYGVHSAMSSALAMRKCPDLLILPPAMDKYRAASRLIMAIYRDYTPDVEPLSLD
ECCCHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCH
EAYLDVSRATRCQGSGTLIAREIRERVRDTVGVTVSAGVAPNKFIAKIASDWNKPDGLFV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHCCCCCCCEEE
VRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCAQLRDWSLFDLHRTFGAFGRRLH
ECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ELARGIDERPVRADQARKSVSVETTYVQDLAALDACAAEIRRLTGLLDARIERAGAARSI
HHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKLYVKIRFADFQRTTVECVADATDAETAVALLAKGLARRRQAVRLLGVGVRIDEDTAER
HHHHEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHH
HGQIALFDDEDMSDEDAEGDEGDEGGEVGEDGEDGEGDEGDASPGA
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PPSDPPPPPSGDAAHLARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRGVIAT
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCCEEEE
CNYDARRYGVHSAMSSALAMRKCPDLLILPPAMDKYRAASRLIMAIYRDYTPDVEPLSLD
ECCCHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCH
EAYLDVSRATRCQGSGTLIAREIRERVRDTVGVTVSAGVAPNKFIAKIASDWNKPDGLFV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHCCCCCCCEEE
VRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCAQLRDWSLFDLHRTFGAFGRRLH
ECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ELARGIDERPVRADQARKSVSVETTYVQDLAALDACAAEIRRLTGLLDARIERAGAARSI
HHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKLYVKIRFADFQRTTVECVADATDAETAVALLAKGLARRRQAVRLLGVGVRIDEDTAER
HHHHEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHH
HGQIALFDDEDMSDEDAEGDEGDEGGEVGEDGEDGEGDEGDASPGA
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]