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The map label for this gene is aceB [H]

Identifier: 237812845

GI number: 237812845

Start: 2535532

End: 2537124

Strand: Direct

Name: aceB [H]

Synonym: GBP346_A2599

Alternate gene names: 237812845

Gene position: 2535532-2537124 (Clockwise)

Preceding gene: 237812844

Following gene: 237812848

Centisome position: 61.86

GC content: 65.79

Gene sequence:

>1593_bases
ATGACCACGACGCTGAAGCTGCCGCAAGGCATGGCGATCACGGGCGAAATCAAGCCCGGCTACGAAGCGATCCTCACGCC
CGAGGCGCTCGAACTCGTCGCGAAGCTGCATCGCCAGTTCGAGCCGCGCCGCCGCGAGCTGCTCGCCGCACGCGTCGAGC
GCACCCAGCGCCTCGACGCCGGCGAGCGCCCCGACTTCCTCGCCGAAACGAAATCGATCCGCGAGGGCGACTGGAAGATC
GCGCCGCTGCCCGCGGACCTGCAATGCCGCCGCGTCGAGATCACGGGCCCCGTCGAGCGCAAGATGATCATCAACGCGCT
GAACTCGGGCGCCGATTCGTACATGACGGACTTCGAGGATTCGAACGCGCCGAGCTGGACCAACCAGATCGACGGCCAGA
TCAACCTGAAGGACGCGGTGCGCCGCACGATCTCGCTCGAACAGAACGGCAAGTCGTACAAGCTCAACGACAAGATCGCG
ACGCTGATCGTGCGCCCGCGCGGCTGGCACCTCGACGAAAAGCACGTGACGGTGGACGGCCAGCGCGTGTCGGGCGGCGT
CTTCGATTTCGCCCTCTTCCTGTTCCACAACGCGCAGGAGCTGATCGCGCGCGGCTCGGGCCCGTACTTCTATCTGCCGA
AGATGGAAAGCCATCTGGAGGCGCGCCTCTGGAACGACATTTTCGTCGCCGCGCAGGAAGCGCTTGGCGTGCCGCGCGGC
ACGATCCGCGCGACCGTGCTGATCGAGACGATCCTCGCCGCGTTCGAGATGGACGAGATCCTGTACGAACTGCGCGAACA
CAGCTCGGGCCTGAACGCGGGCCGCTGGGACTACATCTTCTCGGCGATCAAGAAGTTCAAGAACGACCGCGACTTCTGCC
TCGCCGATCGCGCGAAGATCACGATGACGGTGCCGTTCATGCGCGCCTACGCGCTGCTGCTGCTGAAGACCTGCCACAAG
CGCAACGCGCCCGCGATCGGCGGGATGAGCGCGCTGATCCCGATCAAGAACGATCCGGAAGCGAACGATCGCGCCATGGC
GGGCGTGCGCGCGGACAAGGCGCGCGACGCCGGCGACGGCTATGACGGCGGCTGGGTCGCGCACCCGGGCCTCGTGTCGC
TCGCGATGGAGGAGTTCGTCAAGGTGCTCGGCGACAAGCCGAACCAGATCGGCAAGCAGCGCGACGACGTGCAGATCGAG
GGCAAGAACCTGCTCGATTTCCAGCCGGAAGCGCCGATCACCGAAGCCGGGCTGCGCAACAACATCAACGTCGGCATCCA
CTACCTCGGCTCGTGGCTCGCGGGCAACGGCTGCGTGCCGATCCACAACCTGATGGAAGACGCGGCGACGGCCGAGATCT
CGCGCTCGCAGGTCTGGCAATGGATCCGTTCGCCGAAGGGCACGCTCGACGACGGCCGCAAGGTCACGGCCGAGCTCGTG
CGCGAGTACGCGAAGGTCGAGCTCGCGAACGTGAAGCAGGTTGTCGGCGGAGATACCGCGCCGTACGATCGCGCCGCGGC
GATCTTCGAGCAGATGTCGACGTCGGAGAACTTCACCGAGTTCCTGACGCTGCCGCTCTACGAAGAGATCTGA

Upstream 100 bases:

>100_bases
GCGCGCCCGGCGCCCCGCGTAAGCCGCCTCGGCGCGCCGCCGACCTGATTCATGCAATTGCACCACTCCGTAACTGACTG
ACCGACCAAGGAGAAAACCG

Downstream 100 bases:

>100_bases
GCGGCGCGGGCGGCGGGCGCGAGCGACGCGCACCGCCGCCTGTGCGTCGCTCGCGGATCGGCCGGCTGAAGACGCATTCG
TGCGGCGGACGCCGTGCCAG

Product: malate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MTTTLKLPQGMAITGEIKPGYEAILTPEALELVAKLHRQFEPRRRELLAARVERTQRLDAGERPDFLAETKSIREGDWKI
APLPADLQCRRVEITGPVERKMIINALNSGADSYMTDFEDSNAPSWTNQIDGQINLKDAVRRTISLEQNGKSYKLNDKIA
TLIVRPRGWHLDEKHVTVDGQRVSGGVFDFALFLFHNAQELIARGSGPYFYLPKMESHLEARLWNDIFVAAQEALGVPRG
TIRATVLIETILAAFEMDEILYELREHSSGLNAGRWDYIFSAIKKFKNDRDFCLADRAKITMTVPFMRAYALLLLKTCHK
RNAPAIGGMSALIPIKNDPEANDRAMAGVRADKARDAGDGYDGGWVAHPGLVSLAMEEFVKVLGDKPNQIGKQRDDVQIE
GKNLLDFQPEAPITEAGLRNNINVGIHYLGSWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGTLDDGRKVTAELV
REYAKVELANVKQVVGGDTAPYDRAAAIFEQMSTSENFTEFLTLPLYEEI

Sequences:

>Translated_530_residues
MTTTLKLPQGMAITGEIKPGYEAILTPEALELVAKLHRQFEPRRRELLAARVERTQRLDAGERPDFLAETKSIREGDWKI
APLPADLQCRRVEITGPVERKMIINALNSGADSYMTDFEDSNAPSWTNQIDGQINLKDAVRRTISLEQNGKSYKLNDKIA
TLIVRPRGWHLDEKHVTVDGQRVSGGVFDFALFLFHNAQELIARGSGPYFYLPKMESHLEARLWNDIFVAAQEALGVPRG
TIRATVLIETILAAFEMDEILYELREHSSGLNAGRWDYIFSAIKKFKNDRDFCLADRAKITMTVPFMRAYALLLLKTCHK
RNAPAIGGMSALIPIKNDPEANDRAMAGVRADKARDAGDGYDGGWVAHPGLVSLAMEEFVKVLGDKPNQIGKQRDDVQIE
GKNLLDFQPEAPITEAGLRNNINVGIHYLGSWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGTLDDGRKVTAELV
REYAKVELANVKQVVGGDTAPYDRAAAIFEQMSTSENFTEFLTLPLYEEI
>Mature_529_residues
TTTLKLPQGMAITGEIKPGYEAILTPEALELVAKLHRQFEPRRRELLAARVERTQRLDAGERPDFLAETKSIREGDWKIA
PLPADLQCRRVEITGPVERKMIINALNSGADSYMTDFEDSNAPSWTNQIDGQINLKDAVRRTISLEQNGKSYKLNDKIAT
LIVRPRGWHLDEKHVTVDGQRVSGGVFDFALFLFHNAQELIARGSGPYFYLPKMESHLEARLWNDIFVAAQEALGVPRGT
IRATVLIETILAAFEMDEILYELREHSSGLNAGRWDYIFSAIKKFKNDRDFCLADRAKITMTVPFMRAYALLLLKTCHKR
NAPAIGGMSALIPIKNDPEANDRAMAGVRADKARDAGDGYDGGWVAHPGLVSLAMEEFVKVLGDKPNQIGKQRDDVQIEG
KNLLDFQPEAPITEAGLRNNINVGIHYLGSWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGTLDDGRKVTAELVR
EYAKVELANVKQVVGGDTAPYDRAAAIFEQMSTSENFTEFLTLPLYEEI

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=536, Percent_Identity=50.9328358208955, Blast_Score=525, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI17561814, Length=524, Percent_Identity=51.5267175572519, Blast_Score=523, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI71982926, Length=420, Percent_Identity=53.5714285714286, Blast_Score=441, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6324212, Length=514, Percent_Identity=50.7782101167315, Blast_Score=523, Evalue=1e-149,
Organism=Saccharomyces cerevisiae, GI6322222, Length=514, Percent_Identity=50, Blast_Score=504, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 59205; Mature: 59074

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00510 MALATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTLKLPQGMAITGEIKPGYEAILTPEALELVAKLHRQFEPRRRELLAARVERTQRLDA
CCCEEECCCCCEEEECCCCCCCEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
GERPDFLAETKSIREGDWKIAPLPADLQCRRVEITGPVERKMIINALNSGADSYMTDFED
CCCCCHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCHHHHHHHHHHHCCHHHHHHCCCC
SNAPSWTNQIDGQINLKDAVRRTISLEQNGKSYKLNDKIATLIVRPRGWHLDEKHVTVDG
CCCCCCHHCCCCEEEHHHHHHHHHHHCCCCCCEEECCCEEEEEECCCCCCCCCCEEEECC
QRVSGGVFDFALFLFHNAQELIARGSGPYFYLPKMESHLEARLWNDIFVAAQEALGVPRG
CCCCCHHHHHHHHHHHCHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCC
TIRATVLIETILAAFEMDEILYELREHSSGLNAGRWDYIFSAIKKFKNDRDFCLADRAKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCEE
TMTVPFMRAYALLLLKTCHKRNAPAIGGMSALIPIKNDPEANDRAMAGVRADKARDAGDG
EEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCC
YDGGWVAHPGLVSLAMEEFVKVLGDKPNQIGKQRDDVQIEGKNLLDFQPEAPITEAGLRN
CCCCEECCCHHHHHHHHHHHHHHCCCCHHHCCCCCCEEECCCCEECCCCCCCCHHHCCCC
NINVGIHYLGSWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGTLDDGRKVTAELV
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
REYAKVELANVKQVVGGDTAPYDRAAAIFEQMSTSENFTEFLTLPLYEEI
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCHHHCC
>Mature Secondary Structure 
TTTLKLPQGMAITGEIKPGYEAILTPEALELVAKLHRQFEPRRRELLAARVERTQRLDA
CCEEECCCCCEEEECCCCCCCEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
GERPDFLAETKSIREGDWKIAPLPADLQCRRVEITGPVERKMIINALNSGADSYMTDFED
CCCCCHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCHHHHHHHHHHHCCHHHHHHCCCC
SNAPSWTNQIDGQINLKDAVRRTISLEQNGKSYKLNDKIATLIVRPRGWHLDEKHVTVDG
CCCCCCHHCCCCEEEHHHHHHHHHHHCCCCCCEEECCCEEEEEECCCCCCCCCCEEEECC
QRVSGGVFDFALFLFHNAQELIARGSGPYFYLPKMESHLEARLWNDIFVAAQEALGVPRG
CCCCCHHHHHHHHHHHCHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCC
TIRATVLIETILAAFEMDEILYELREHSSGLNAGRWDYIFSAIKKFKNDRDFCLADRAKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCEE
TMTVPFMRAYALLLLKTCHKRNAPAIGGMSALIPIKNDPEANDRAMAGVRADKARDAGDG
EEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCC
YDGGWVAHPGLVSLAMEEFVKVLGDKPNQIGKQRDDVQIEGKNLLDFQPEAPITEAGLRN
CCCCEECCCHHHHHHHHHHHHHHCCCCHHHCCCCCCEEECCCCEECCCCCCCCHHHCCCC
NINVGIHYLGSWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGTLDDGRKVTAELV
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
REYAKVELANVKQVVGGDTAPYDRAAAIFEQMSTSENFTEFLTLPLYEEI
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA