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The map label for this gene is cdsA [H]

Identifier: 237812803

GI number: 237812803

Start: 2489803

End: 2490624

Strand: Reverse

Name: cdsA [H]

Synonym: GBP346_A2557

Alternate gene names: 237812803

Gene position: 2490624-2489803 (Counterclockwise)

Preceding gene: 237812804

Following gene: 237812802

Centisome position: 60.77

GC content: 72.63

Gene sequence:

>822_bases
ATGCTGAAGACCCGTGTCATCACGGCGGTCGTGCTGCTGGCGGTGCTGCTGCCCGTGACGCTGTTCGCGCCGCTCGCCGC
GTTCGGCGCGCTGATCGCGCTCGCGCTCGTATTCGCCGCGTGGGAGTGGGGGCGGCTGTTGAAGCTGGGCGGCGCGGGCC
CGCTCGCGTACGCGGCCGTCGCGGCGCTCGCGCTCGGCGCGAGCACGCGGCTCGGCATCGGCGCGGCCGCCGCGCGGCCG
CTGTTCGCGGCCGCGGGGGTGTTCTGGCTGCTGGCGGGCCCGTACGCGCTCTGGCGCAAGCCCGCGCTCGCCGAGCGCGC
GTGGAAGCCGTTCCTGCTCGTCGCGGGCCTCGTCGTCTTCTCGGCGTGCTGGCACGCGCTCGTCGCCGCGCGCGCGCAAG
GCGTACCCTTCGTGTTGTCGCTGTTGGTAGTGGTATGGCTCGCCGATATCGGCGCATACTTCGCCGGAAAGGCGTTCGGC
AAGCACAAGCTCGCGCCGTCGGTGAGCCCCGGCAAAACCTGGGAAGGCGCGGCGGGCGGCTGGCTCGCGGTGATGATCGT
CGCCGGCGCGGCTGTCGCGGCGCACGCCTTCGAACCGACCCTTTATTCGACGTTCGTCGCGCGGTACGGTGCGGCGGGCG
CATTCGCGGCGCTCACGGTGCTCGTCGCGTTCAGCGTGGTCGGCGACCTGTTCGAGTCGATGCTCAAGCGCCAGGCCGGC
GTGAAAGATTCGAGCGGCCTCCTGCCGGGCCACGGCGGCGTGCTCGACCGCGTCGACGCGCTGCTGCCCGTGCTGCCGCT
CGCGATGCTGCTGCTCGGTTAA

Upstream 100 bases:

>100_bases
CGCTCGCCGAAGCGCTCGCGTCGTACACGCACCGCGAACGCCGCTTCGGCCGCACGAGCGCGCAGCTCGAACCCCAGGCC
CAGGACGCCGATTCCCTTTC

Downstream 100 bases:

>100_bases
AACTAGACCCTATTATGCAAAAACGTCTGACATTGCTCGGTTCGACGGGCTCGATCGGAGACAGCACGCTCGACGTCGTC
GCGCGTCATCCGGAACGCTT

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MLKTRVITAVVLLAVLLPVTLFAPLAAFGALIALALVFAAWEWGRLLKLGGAGPLAYAAVAALALGASTRLGIGAAAARP
LFAAAGVFWLLAGPYALWRKPALAERAWKPFLLVAGLVVFSACWHALVAARAQGVPFVLSLLVVVWLADIGAYFAGKAFG
KHKLAPSVSPGKTWEGAAGGWLAVMIVAGAAVAAHAFEPTLYSTFVARYGAAGAFAALTVLVAFSVVGDLFESMLKRQAG
VKDSSGLLPGHGGVLDRVDALLPVLPLAMLLLG

Sequences:

>Translated_273_residues
MLKTRVITAVVLLAVLLPVTLFAPLAAFGALIALALVFAAWEWGRLLKLGGAGPLAYAAVAALALGASTRLGIGAAAARP
LFAAAGVFWLLAGPYALWRKPALAERAWKPFLLVAGLVVFSACWHALVAARAQGVPFVLSLLVVVWLADIGAYFAGKAFG
KHKLAPSVSPGKTWEGAAGGWLAVMIVAGAAVAAHAFEPTLYSTFVARYGAAGAFAALTVLVAFSVVGDLFESMLKRQAG
VKDSSGLLPGHGGVLDRVDALLPVLPLAMLLLG
>Mature_273_residues
MLKTRVITAVVLLAVLLPVTLFAPLAAFGALIALALVFAAWEWGRLLKLGGAGPLAYAAVAALALGASTRLGIGAAAARP
LFAAAGVFWLLAGPYALWRKPALAERAWKPFLLVAGLVVFSACWHALVAARAQGVPFVLSLLVVVWLADIGAYFAGKAFG
KHKLAPSVSPGKTWEGAAGGWLAVMIVAGAAVAAHAFEPTLYSTFVARYGAAGAFAALTVLVAFSVVGDLFESMLKRQAG
VKDSSGLLPGHGGVLDRVDALLPVLPLAMLLLG

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=296, Percent_Identity=34.1216216216216, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787677, Length=119, Percent_Identity=40.3361344537815, Blast_Score=81, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 28032; Mature: 28032

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8654980; 10984043 [H]