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The map label for this gene is ldcA [H]

Identifier: 237812752

GI number: 237812752

Start: 2443765

End: 2444706

Strand: Reverse

Name: ldcA [H]

Synonym: GBP346_A2505

Alternate gene names: 237812752

Gene position: 2444706-2443765 (Counterclockwise)

Preceding gene: 237812753

Following gene: 237812751

Centisome position: 59.65

GC content: 67.62

Gene sequence:

>942_bases
ATGATTTCCACGCCCTGCACGCCGCGCACGATTCGTCTGCTTGCCCCGTCCGGTTATCCGCACGATCCCGCCGCGATCGA
GCGCGCGCTCGAACGCCTGAGCGACGAGCAGCATCGAATCCAGAATCTCGACGCGACGCAACGCCGCTATCAGCGCTTCG
CCGGCACCGACGGCGAGCGGGCAGGCGACCTGAACCGGCTTGCGGACCCGTCGTTGCCGCTGCCCGACATCGGCCTCGCG
GTGCGCGGCGGCTACGGCGCCGCGCGGATCCTGCACGGGCTCGACTATCGCGGCCTCGAACGCCGGCTGCGCGACCAGCC
GATCGCGCTCGTCGGCCACAGCGACTTCACCGCGATCCAGCTCGCGCTCTATGCGAAGGCGCGCGTGAAGACGTTCGGCG
GCCCGATGCTGTCGGCCGATTTCGGCGCGCCGACGCCGAGCGAGTTCACGCTTGCGCATTTCTGGCAGACCCTCACGCAG
CCGACGACGACGATCGTCTCCGACGTGCCGCAGACGCAGGTCGTCAACGCATCGGGCACGCTATGGGGCGGCAATCTCGC
GATCCTCGCGTCGCTCGTCGGCACGCCGTACATGCCGCAGATCGAAGGGGGGATCCTGTTCGTCGAGGATGTGAACGAGC
AGCCGTTCAGGATCGAGCGGATGATCTATCAGCTGCATCTCGCGGGCATCCTCGCACGCCAGCAGGCGCTCGTGCTCGGC
CAGTTCACGGGCGCGCGCCCGTTCGATTACGACAACGGCTACGACATGCAGGCGATGATCGAGCAGGTGCGCGGCGTGAT
CGGCATCCCGATCGTCACCGGGTTGCAGTTCGGTCACGTGCCCGATCTGCTGACGCTGCCGTTCGGCGCGCGCGCGGAGC
TCGTCGCGAACGAGCACGGTTTCAGGCTGACGATGTCCGACTATCCGCATCTCGCCGCATGA

Upstream 100 bases:

>100_bases
CGCCGCGCGCAGCAGGCGCCCGGCGCGCCGCCGCGCGACGAGTGAACCGCGCGGCGCGGGACGCCTCTAACTACGTCCGA
TCGATTCTTCCTGCGAATTC

Downstream 100 bases:

>100_bases
GCGGGACGAAAGTCGATGCGAAGCAAAAAGGCGGGTGACCGCCTTTTTTTGCGCTCGTTGTTGCAACTAACGGTCAATTA
TCTTCGAGGGCTCGGGTGGT

Product: L,D-carboxypeptidase A

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MISTPCTPRTIRLLAPSGYPHDPAAIERALERLSDEQHRIQNLDATQRRYQRFAGTDGERAGDLNRLADPSLPLPDIGLA
VRGGYGAARILHGLDYRGLERRLRDQPIALVGHSDFTAIQLALYAKARVKTFGGPMLSADFGAPTPSEFTLAHFWQTLTQ
PTTTIVSDVPQTQVVNASGTLWGGNLAILASLVGTPYMPQIEGGILFVEDVNEQPFRIERMIYQLHLAGILARQQALVLG
QFTGARPFDYDNGYDMQAMIEQVRGVIGIPIVTGLQFGHVPDLLTLPFGARAELVANEHGFRLTMSDYPHLAA

Sequences:

>Translated_313_residues
MISTPCTPRTIRLLAPSGYPHDPAAIERALERLSDEQHRIQNLDATQRRYQRFAGTDGERAGDLNRLADPSLPLPDIGLA
VRGGYGAARILHGLDYRGLERRLRDQPIALVGHSDFTAIQLALYAKARVKTFGGPMLSADFGAPTPSEFTLAHFWQTLTQ
PTTTIVSDVPQTQVVNASGTLWGGNLAILASLVGTPYMPQIEGGILFVEDVNEQPFRIERMIYQLHLAGILARQQALVLG
QFTGARPFDYDNGYDMQAMIEQVRGVIGIPIVTGLQFGHVPDLLTLPFGARAELVANEHGFRLTMSDYPHLAA
>Mature_313_residues
MISTPCTPRTIRLLAPSGYPHDPAAIERALERLSDEQHRIQNLDATQRRYQRFAGTDGERAGDLNRLADPSLPLPDIGLA
VRGGYGAARILHGLDYRGLERRLRDQPIALVGHSDFTAIQLALYAKARVKTFGGPMLSADFGAPTPSEFTLAHFWQTLTQ
PTTTIVSDVPQTQVVNASGTLWGGNLAILASLVGTPYMPQIEGGILFVEDVNEQPFRIERMIYQLHLAGILARQQALVLG
QFTGARPFDYDNGYDMQAMIEQVRGVIGIPIVTGLQFGHVPDLLTLPFGARAELVANEHGFRLTMSDYPHLAA

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=299, Percent_Identity=49.8327759197324, Blast_Score=288, Evalue=4e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 34307; Mature: 34307

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTPCTPRTIRLLAPSGYPHDPAAIERALERLSDEQHRIQNLDATQRRYQRFAGTDGER
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHCCCCCCC
AGDLNRLADPSLPLPDIGLAVRGGYGAARILHGLDYRGLERRLRDQPIALVGHSDFTAIQ
CCCHHHHCCCCCCCCCCCEEEECCCHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCHHHH
LALYAKARVKTFGGPMLSADFGAPTPSEFTLAHFWQTLTQPTTTIVSDVPQTQVVNASGT
HHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCEEEECCCC
LWGGNLAILASLVGTPYMPQIEGGILFVEDVNEQPFRIERMIYQLHLAGILARQQALVLG
EECCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEE
QFTGARPFDYDNGYDMQAMIEQVRGVIGIPIVTGLQFGHVPDLLTLPFGARAELVANEHG
ECCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHCCCCCCCCCEEECCCCCCEEEEECCCC
FRLTMSDYPHLAA
CEEEECCCCCCCC
>Mature Secondary Structure
MISTPCTPRTIRLLAPSGYPHDPAAIERALERLSDEQHRIQNLDATQRRYQRFAGTDGER
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHCCCCCCC
AGDLNRLADPSLPLPDIGLAVRGGYGAARILHGLDYRGLERRLRDQPIALVGHSDFTAIQ
CCCHHHHCCCCCCCCCCCEEEECCCHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCHHHH
LALYAKARVKTFGGPMLSADFGAPTPSEFTLAHFWQTLTQPTTTIVSDVPQTQVVNASGT
HHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCEEEECCCC
LWGGNLAILASLVGTPYMPQIEGGILFVEDVNEQPFRIERMIYQLHLAGILARQQALVLG
EECCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEE
QFTGARPFDYDNGYDMQAMIEQVRGVIGIPIVTGLQFGHVPDLLTLPFGARAELVANEHG
ECCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHCCCCCCCCCEEECCCCCCEEEEECCCC
FRLTMSDYPHLAA
CEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]