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The map label for this gene is ppiD [H]

Identifier: 237812671

GI number: 237812671

Start: 2375726

End: 2377660

Strand: Reverse

Name: ppiD [H]

Synonym: GBP346_A2421

Alternate gene names: 237812671

Gene position: 2377660-2375726 (Counterclockwise)

Preceding gene: 237812672

Following gene: 237812670

Centisome position: 58.01

GC content: 66.87

Gene sequence:

>1935_bases
ATGCTCGATTTCTTTCGCAATCACCAGCGCCTGATGATGTTCTTCCTGCTCCTGATCGTGCTGCCGGGGCTTGGGATCGT
CGGCATTCAGGGTTTCCGTGGGTTCTTCGATGAAAGCGCGAACGTCGCGGCCGTCAACGGGCACAAGATCACGCGCGCCG
AATTCGACGGCACGCTGCGCCAGCAGGTCGATCAGGCGCGCCAGGTGCTGGGCGCGCAGTTCGACGCGAAAGCGTTCGAC
ACGCCGGAGCGCCGTCAGCAGCTTCTCGACGGGCTGATTCAGCAGCGCGCGCTCGCCGACGAGACGCAGCGTCTGCATCT
GAGCGCGTCGGATGGCGCGGTGCGCCAGACGCTGCTGAGCGATCCGGTGATCGCGTCGCTGAAAAAGGCGGACGGCTCGT
TCGACGCCGAGCGCTATACGCAGATGCTCGCGATGCAGGGCATGACGCCCGATCAATACCAGGAGCGCGTGCGTTACAAC
CTCGCGCTGCAGCAGATTCCGGCCAGCATCGTATCGAGCGCGTTCACGCCGAAGAGCGTCGCGCGTCGTCTGACCGAACT
CGCCGAGCAGCAGCGCGAAGTGCAGCCGATGGTGCTGAAGTCGGCCGACTATGCGGCGAAGGTGCAGCCGACCGACGCGC
AGATCTCCGCCTACTACGATGCCCACAAGCAGGCGTTCGCGACGCGCGAGACGGCAACGATCCAGTATCTCGTCTACTCG
CAGGCGGCCGCCGCCGCCGCGGCGCAGCCGAGCGACGTCGACATCAAGAAGTATTACGACGACAACATCGCGCATTACCG
CACGGACGCGCAGGTGCGCGTGAGCCACATCTTCATCGCCGCGGCGAAGGACGCGAGCGCGGCCGAGAAGGCCGCCGCGA
AGGCGAAGGCCGAGCAGTTGCTCGCCGAAGTGAAGGCGCATCCGGACCGGTTCGCGCAGATCGCCGAGAAGAACTCGCAG
GATGCGCCGTCGGCGGCGAAGGGGGGCGACCTCGGCTTCATCACGCGCGGCTCGACGGCGGGCGGCGCGGCGTTCGACGA
CGCCGCGTTCGCGCTGAAGAAGGACGAAATCAGCGGTGTCGTGCAGGGCGATTTCGGCTTCCATATCCTGAAGGCGACCG
ACGTGAAGCCGGCCGTCGTGAAGCCGCTCGCGGAAGTGAAGGATTCGATCGCGACGGACCTGAGGCAGCAGTTCGCGGCG
AAGGCGTTCGCCGACAACGCGGAAGGCTTCACGTCGACCGTCTACGAGAAGGCGAAGAGCCTGCAGCCCGCCGCCGACAA
GTACAAGCTGACCATCCAGACCGCGACGGTGTCGCCGCAGCCGAACCCCGCGCTGCCGCCCGACAGCCCGCTCAACAACG
CGAAGTTCCTCGCGGCCGTGTTCGCGGCCGATTCGGTGAAGAACGGCAACAACACGCAGGCGATCGACATCGGCAACAAT
ACGCTGATCGCCGCGCGCGTGACGAATCACCAGCCGTCGACCGTGCCCGCGCTCGATGCGATCAAGGATCAGGTGCGCGC
GAAGGTCGTCGCCGACGAGGCAGCGCGCCTCGCGCAGCAGGCCGGCGAGGCGAAGCTCGCGGAACTGCGCAAGTCGAAGT
CGACGGCGGGCTTCGCCGCGCCCGACAAGATCTCGCGCACGCAGGCGCACGGCCTGCCCCCCGCGGCCGTCAGCGCGATC
TACAAGGTCGATCCGAAGACGCTGCCCGCCTATGTCGGCGTGGATCTCGGCAACGACGGCTACGCGATCTTCCGCGTGAA
TTCGGTGGTCGCGGCGGCGCCCGCCGACGATCAGCGTCTCGCGGCCGCTCAGCAGCAACTCGCGCAGGTGTATGCGCAGA
GCGAGACGCAGGCGTATCTCGCGTCGCTGCGCGCTCGCTCGAAGGTCAAGCTCTACGGTTCGACCGCCGGCGGCGCGCAG
GACAGCTCGAACTGA

Upstream 100 bases:

>100_bases
CGTCCGCTCCGCCATCATCCCGAAAGGCGAACTCCGGTTCGCCTTTTTTCTTGCCCGCTGTTGTAATATCGGGCGTTTTG
TCCAGCTCACGCCGTCACGC

Downstream 100 bases:

>100_bases
CGGTAGACGAAGACGGCGCGCTGGCGCGCCCGTTCGATGAAAGACAGCCCCGCCATCGTGCGGGGCTGTTTCGTTTCGGC
GAGCGTGCGAGCCGGGTTTC

Product: peptidyl-prolyl cis-trans isomerase D

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MLDFFRNHQRLMMFFLLLIVLPGLGIVGIQGFRGFFDESANVAAVNGHKITRAEFDGTLRQQVDQARQVLGAQFDAKAFD
TPERRQQLLDGLIQQRALADETQRLHLSASDGAVRQTLLSDPVIASLKKADGSFDAERYTQMLAMQGMTPDQYQERVRYN
LALQQIPASIVSSAFTPKSVARRLTELAEQQREVQPMVLKSADYAAKVQPTDAQISAYYDAHKQAFATRETATIQYLVYS
QAAAAAAAQPSDVDIKKYYDDNIAHYRTDAQVRVSHIFIAAAKDASAAEKAAAKAKAEQLLAEVKAHPDRFAQIAEKNSQ
DAPSAAKGGDLGFITRGSTAGGAAFDDAAFALKKDEISGVVQGDFGFHILKATDVKPAVVKPLAEVKDSIATDLRQQFAA
KAFADNAEGFTSTVYEKAKSLQPAADKYKLTIQTATVSPQPNPALPPDSPLNNAKFLAAVFAADSVKNGNNTQAIDIGNN
TLIAARVTNHQPSTVPALDAIKDQVRAKVVADEAARLAQQAGEAKLAELRKSKSTAGFAAPDKISRTQAHGLPPAAVSAI
YKVDPKTLPAYVGVDLGNDGYAIFRVNSVVAAAPADDQRLAAAQQQLAQVYAQSETQAYLASLRARSKVKLYGSTAGGAQ
DSSN

Sequences:

>Translated_644_residues
MLDFFRNHQRLMMFFLLLIVLPGLGIVGIQGFRGFFDESANVAAVNGHKITRAEFDGTLRQQVDQARQVLGAQFDAKAFD
TPERRQQLLDGLIQQRALADETQRLHLSASDGAVRQTLLSDPVIASLKKADGSFDAERYTQMLAMQGMTPDQYQERVRYN
LALQQIPASIVSSAFTPKSVARRLTELAEQQREVQPMVLKSADYAAKVQPTDAQISAYYDAHKQAFATRETATIQYLVYS
QAAAAAAAQPSDVDIKKYYDDNIAHYRTDAQVRVSHIFIAAAKDASAAEKAAAKAKAEQLLAEVKAHPDRFAQIAEKNSQ
DAPSAAKGGDLGFITRGSTAGGAAFDDAAFALKKDEISGVVQGDFGFHILKATDVKPAVVKPLAEVKDSIATDLRQQFAA
KAFADNAEGFTSTVYEKAKSLQPAADKYKLTIQTATVSPQPNPALPPDSPLNNAKFLAAVFAADSVKNGNNTQAIDIGNN
TLIAARVTNHQPSTVPALDAIKDQVRAKVVADEAARLAQQAGEAKLAELRKSKSTAGFAAPDKISRTQAHGLPPAAVSAI
YKVDPKTLPAYVGVDLGNDGYAIFRVNSVVAAAPADDQRLAAAQQQLAQVYAQSETQAYLASLRARSKVKLYGSTAGGAQ
DSSN
>Mature_644_residues
MLDFFRNHQRLMMFFLLLIVLPGLGIVGIQGFRGFFDESANVAAVNGHKITRAEFDGTLRQQVDQARQVLGAQFDAKAFD
TPERRQQLLDGLIQQRALADETQRLHLSASDGAVRQTLLSDPVIASLKKADGSFDAERYTQMLAMQGMTPDQYQERVRYN
LALQQIPASIVSSAFTPKSVARRLTELAEQQREVQPMVLKSADYAAKVQPTDAQISAYYDAHKQAFATRETATIQYLVYS
QAAAAAAAQPSDVDIKKYYDDNIAHYRTDAQVRVSHIFIAAAKDASAAEKAAAKAKAEQLLAEVKAHPDRFAQIAEKNSQ
DAPSAAKGGDLGFITRGSTAGGAAFDDAAFALKKDEISGVVQGDFGFHILKATDVKPAVVKPLAEVKDSIATDLRQQFAA
KAFADNAEGFTSTVYEKAKSLQPAADKYKLTIQTATVSPQPNPALPPDSPLNNAKFLAAVFAADSVKNGNNTQAIDIGNN
TLIAARVTNHQPSTVPALDAIKDQVRAKVVADEAARLAQQAGEAKLAELRKSKSTAGFAAPDKISRTQAHGLPPAAVSAI
YKVDPKTLPAYVGVDLGNDGYAIFRVNSVVAAAPADDQRLAAAQQQLAQVYAQSETQAYLASLRARSKVKLYGSTAGGAQ
DSSN

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=649, Percent_Identity=28.0431432973806, Blast_Score=183, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69097; Mature: 69097

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFFRNHQRLMMFFLLLIVLPGLGIVGIQGFRGFFDESANVAAVNGHKITRAEFDGTLR
CCCHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHCCCCCEEEECCCEEEHHHHCCHHH
QQVDQARQVLGAQFDAKAFDTPERRQQLLDGLIQQRALADETQRLHLSASDGAVRQTLLS
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHC
DPVIASLKKADGSFDAERYTQMLAMQGMTPDQYQERVRYNLALQQIPASIVSSAFTPKSV
CHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ARRLTELAEQQREVQPMVLKSADYAAKVQPTDAQISAYYDAHKQAFATRETATIQYLVYS
HHHHHHHHHHHHCCCCHHEECCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHH
QAAAAAAAQPSDVDIKKYYDDNIAHYRTDAQVRVSHIFIAAAKDASAAEKAAAKAKAEQL
HHHHHHCCCCCCCCHHHHHCCCHHHEECCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHH
LAEVKAHPDRFAQIAEKNSQDAPSAAKGGDLGFITRGSTAGGAAFDDAAFALKKDEISGV
HHHHHHCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHEEHHHCCCE
VQGDFGFHILKATDVKPAVVKPLAEVKDSIATDLRQQFAAKAFADNAEGFTSTVYEKAKS
EECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
LQPAADKYKLTIQTATVSPQPNPALPPDSPLNNAKFLAAVFAADSVKNGNNTQAIDIGNN
CCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCC
TLIAARVTNHQPSTVPALDAIKDQVRAKVVADEAARLAQQAGEAKLAELRKSKSTAGFAA
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
PDKISRTQAHGLPPAAVSAIYKVDPKTLPAYVGVDLGNDGYAIFRVNSVVAAAPADDQRL
CCHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCEEEECCCCHHHH
AAAQQQLAQVYAQSETQAYLASLRARSKVKLYGSTAGGAQDSSN
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLDFFRNHQRLMMFFLLLIVLPGLGIVGIQGFRGFFDESANVAAVNGHKITRAEFDGTLR
CCCHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHCCCCCEEEECCCEEEHHHHCCHHH
QQVDQARQVLGAQFDAKAFDTPERRQQLLDGLIQQRALADETQRLHLSASDGAVRQTLLS
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHC
DPVIASLKKADGSFDAERYTQMLAMQGMTPDQYQERVRYNLALQQIPASIVSSAFTPKSV
CHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ARRLTELAEQQREVQPMVLKSADYAAKVQPTDAQISAYYDAHKQAFATRETATIQYLVYS
HHHHHHHHHHHHCCCCHHEECCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHH
QAAAAAAAQPSDVDIKKYYDDNIAHYRTDAQVRVSHIFIAAAKDASAAEKAAAKAKAEQL
HHHHHHCCCCCCCCHHHHHCCCHHHEECCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHH
LAEVKAHPDRFAQIAEKNSQDAPSAAKGGDLGFITRGSTAGGAAFDDAAFALKKDEISGV
HHHHHHCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHEEHHHCCCE
VQGDFGFHILKATDVKPAVVKPLAEVKDSIATDLRQQFAAKAFADNAEGFTSTVYEKAKS
EECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
LQPAADKYKLTIQTATVSPQPNPALPPDSPLNNAKFLAAVFAADSVKNGNNTQAIDIGNN
CCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCC
TLIAARVTNHQPSTVPALDAIKDQVRAKVVADEAARLAQQAGEAKLAELRKSKSTAGFAA
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
PDKISRTQAHGLPPAAVSAIYKVDPKTLPAYVGVDLGNDGYAIFRVNSVVAAAPADDQRL
CCHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCEEEECCCCHHHH
AAAQQQLAQVYAQSETQAYLASLRARSKVKLYGSTAGGAQDSSN
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]