Click here to switch to the map view.

The map label for this gene is arnA_1 [H]

Identifier: 237812597

GI number: 237812597

Start: 2312003

End: 2312950

Strand: Direct

Name: arnA_1 [H]

Synonym: GBP346_A2347

Alternate gene names: 237812597

Gene position: 2312003-2312950 (Clockwise)

Preceding gene: 237812596

Following gene: 237812598

Centisome position: 56.41

GC content: 71.1

Gene sequence:

>948_bases
ATGAAGCCGCGCGCCGTCGTCTTCGCGTATCACAACGTCGGCGTGCGCTGCCTGCAGGTACTGCTCGCGCGCGGCGTGGA
CGTCGCGCTCGTCGTCACGCACGAAGACAGCCCGACCGAGCACATCTGGTTCGGCAGCGTCGCGGCGGTCGCGGCCGAGC
ACGGCATCGCGGTCATCACGCCCGCCGATCCGGCCGGCGCCGACGTGCGCGCGGCGCTCGCGAGCGCGAAGCCCGATTTC
ATCTTCTCGTTCTATTACCGGCACATGCTGCCCGTCGACCTCCTCGCGCTCGCCGCGCGCGGCGCGTACAACATGCACGG
CTCGCTGCTGCCGAAGTACCGCGGCCGCGTGCCGACGAACTGGGCGGTGCTCAACGGCGAGACCGAAACCGGCGCGACGC
TGCACGAAATGGCCGCGAAGCCCGATGCGGGCGCGATCGTCGGGCAGACCGCGGTGCCGATCCTGCCCGACGACACCGCC
GCGCAGGTGTTCGACAAGGTCACCGTCGCCGCGGAGCAGACGCTCTGGCGCGTGCTGCCCGCGCTGCTCGCGGGCGAAGC
GCCGCACCTGCCGAACGATCTGTCGCAGGGCAGCTACTACGGCGGGCGCAAGCCCGAGGACGGGCGCATCGACTGGACGC
AGCCGGCCGCGAACGTGTACAACCTGATCCGCGCGGTCGCGCCGCCGTATCCGGGCGCGTTCACCGATCTCGGCGGCACG
CGCTTCGTGATCGCGCGCGCGCGGCTCGCCGCGCCCGGCACAGCCGCCGCGCGCGCGGCCGTCGATTTGCCGCCGGGCCT
GCACGTAAGCGATAATGCGCTGTTCGGCGTTTGCGGCGACAGCCGCGCCGTCTCCATTCTCGAACTGCGCCGGCCGCACG
ACGGCGGCGAAGCCGTCGTTTCCCCGGCGCAATTCGCGCAGTTCATTCATTCTTCCCGTCATTCATGA

Upstream 100 bases:

>100_bases
AGGTCCGCGCGCGGCCGCGCTACCTGATCCACACCGTGCTCGAGGCGCGCGACGGCAAGCCCGGCGTCACGCTCGCCGCC
GAGCGCCGCGAGGCCGCGCG

Downstream 100 bases:

>100_bases
AAGCAAAAAAAGTCCTGATCCTGGGTGTGAACGGCTTCATCGGTCATCACCTGTCCAAGCGCATTCTTGAAACCACCGAT
TGGGAAGTGTTCGGCATGGA

Product: putative formyltransferase

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKPRAVVFAYHNVGVRCLQVLLARGVDVALVVTHEDSPTEHIWFGSVAAVAAEHGIAVITPADPAGADVRAALASAKPDF
IFSFYYRHMLPVDLLALAARGAYNMHGSLLPKYRGRVPTNWAVLNGETETGATLHEMAAKPDAGAIVGQTAVPILPDDTA
AQVFDKVTVAAEQTLWRVLPALLAGEAPHLPNDLSQGSYYGGRKPEDGRIDWTQPAANVYNLIRAVAPPYPGAFTDLGGT
RFVIARARLAAPGTAAARAAVDLPPGLHVSDNALFGVCGDSRAVSILELRRPHDGGEAVVSPAQFAQFIHSSRHS

Sequences:

>Translated_315_residues
MKPRAVVFAYHNVGVRCLQVLLARGVDVALVVTHEDSPTEHIWFGSVAAVAAEHGIAVITPADPAGADVRAALASAKPDF
IFSFYYRHMLPVDLLALAARGAYNMHGSLLPKYRGRVPTNWAVLNGETETGATLHEMAAKPDAGAIVGQTAVPILPDDTA
AQVFDKVTVAAEQTLWRVLPALLAGEAPHLPNDLSQGSYYGGRKPEDGRIDWTQPAANVYNLIRAVAPPYPGAFTDLGGT
RFVIARARLAAPGTAAARAAVDLPPGLHVSDNALFGVCGDSRAVSILELRRPHDGGEAVVSPAQFAQFIHSSRHS
>Mature_315_residues
MKPRAVVFAYHNVGVRCLQVLLARGVDVALVVTHEDSPTEHIWFGSVAAVAAEHGIAVITPADPAGADVRAALASAKPDF
IFSFYYRHMLPVDLLALAARGAYNMHGSLLPKYRGRVPTNWAVLNGETETGATLHEMAAKPDAGAIVGQTAVPILPDDTA
AQVFDKVTVAAEQTLWRVLPALLAGEAPHLPNDLSQGSYYGGRKPEDGRIDWTQPAANVYNLIRAVAPPYPGAFTDLGGT
RFVIARARLAAPGTAAARAAVDLPPGLHVSDNALFGVCGDSRAVSILELRRPHDGGEAVVSPAQFAQFIHSSRHS

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=181, Percent_Identity=25.414364640884, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI238814322, Length=210, Percent_Identity=24.2857142857143, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788589, Length=304, Percent_Identity=40.7894736842105, Blast_Score=231, Evalue=5e-62,
Organism=Escherichia coli, GI1789683, Length=259, Percent_Identity=29.3436293436293, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 33353; Mature: 33353

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPRAVVFAYHNVGVRCLQVLLARGVDVALVVTHEDSPTEHIWFGSVAAVAAEHGIAVIT
CCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCEEEHHHHHHHHHHCCEEEEE
PADPAGADVRAALASAKPDFIFSFYYRHMLPVDLLALAARGAYNMHGSLLPKYRGRVPTN
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCC
WAVLNGETETGATLHEMAAKPDAGAIVGQTAVPILPDDTAAQVFDKVTVAAEQTLWRVLP
EEEEECCCCCCCHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALLAGEAPHLPNDLSQGSYYGGRKPEDGRIDWTQPAANVYNLIRAVAPPYPGAFTDLGGT
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHCCCCCCCCCCCCCC
RFVIARARLAAPGTAAARAAVDLPPGLHVSDNALFGVCGDSRAVSILELRRPHDGGEAVV
EEEEEEHHHCCCCCHHHHEEECCCCCCEECCCCEEEEECCCCCEEEEEECCCCCCCHHEE
SPAQFAQFIHSSRHS
CHHHHHHHHHHCCCC
>Mature Secondary Structure
MKPRAVVFAYHNVGVRCLQVLLARGVDVALVVTHEDSPTEHIWFGSVAAVAAEHGIAVIT
CCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCEEEHHHHHHHHHHCCEEEEE
PADPAGADVRAALASAKPDFIFSFYYRHMLPVDLLALAARGAYNMHGSLLPKYRGRVPTN
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCC
WAVLNGETETGATLHEMAAKPDAGAIVGQTAVPILPDDTAAQVFDKVTVAAEQTLWRVLP
EEEEECCCCCCCHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALLAGEAPHLPNDLSQGSYYGGRKPEDGRIDWTQPAANVYNLIRAVAPPYPGAFTDLGGT
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHCCCCCCCCCCCCCC
RFVIARARLAAPGTAAARAAVDLPPGLHVSDNALFGVCGDSRAVSILELRRPHDGGEAVV
EEEEEEHHHCCCCCHHHHEEECCCCCCEECCCCEEEEECCCCCEEEEEECCCCCCCHHEE
SPAQFAQFIHSSRHS
CHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA