Click here to switch to the map view.

The map label for this gene is engA [H]

Identifier: 237812544

GI number: 237812544

Start: 2261144

End: 2262526

Strand: Reverse

Name: engA [H]

Synonym: GBP346_A2293

Alternate gene names: 237812544

Gene position: 2262526-2261144 (Counterclockwise)

Preceding gene: 237812546

Following gene: 237812543

Centisome position: 55.2

GC content: 65.94

Gene sequence:

>1383_bases
ATGCGGGCTCACCGCCGCTGCGTTTCACGTAGACGACATCATCAGATGAAACCGGTCATTGCCCTCGTTGGGCGCCCCAA
TGTGGGGAAATCCACGCTGTTCAACCGGCTCACGCGCTCGCGCGATGCGCTGGTCGCCGATCTGCCCGGCCTCACGCGCG
ATCGCCATTACGGCGAGGGGCGGGTTGGCGCGCGGCCGTACCTCGTCGTCGACACGGGCGGCTTCGAGCCCGTCGCGAAG
GACGGCATCCTGCACGAGATGGCGCGCCAGACGCGCCAGGCGGTCGAGGAGGCGGACGTCGTCGTGTTCATCGTCGACGG
CCGCAACGGCCTCGCGCCGCAGGACAAGTCGATCGCCGATTATCTGCGCAAGACCGGCCGGCCGATCTTCCTCGTCGTCA
ACAAGGCCGAGGGGATGAAATACACGGCGGTCGCGTCGGATTTCTACGAGCTCGGCCTGGGCGATCCGCGCGCGATCTCG
GCCGCGCACGGCGACGGCGTGAACGACATGATCAACGAGGCGCTCGAAGTCGCGTACGCGGGCGAGCCGCAGGAGAGCGA
GGAGGCCGCCGCCGCGCGCGGCATCAAGATCGCGATCGTGGGCCGGCCGAACGTCGGCAAGTCCACGCTCGTCAACACGT
TGATCGGCGAAGACCGCGTGATCGCGTTCGATATGCCCGGCACGACGCGCGATTCGATCTACGTCGACTTCGAGCGCAAC
GGCAAGCACTACACGCTGATCGACACGGCGGGCCTGCGCCGGCGCGGCAAGGTGTTCGAGGCGATCGAGAAGTTCTCGGT
CGTGAAGACGTTGCAGTCGATCTCCGACGCGAACGTGGTGATTCTTCTGCTCGATGCGCGCCAGGATATTTCCGATCAGG
ACGCGCACATCGCGGGCTTCGTCGTCGAGCAGGGCCGCGCGCTCGTCGTCGGCGTGAACAAATGGGACGGGCTCGATCCG
CACGTGCGCGAGCGGACGAAGGCGGATCTCGCGCGCAAGCTGAAATTCCTCGAGTTCGCGAAGTTCCATTTCATCTCGGC
CGCGGAGAAAACCGGCATCGGCGCGCTGATGCGTTCGGTCGACGACGCCTACGCGGCCGCGATGAAGAAGCTGCCGACGC
CGAAGCTCACGCGCGCGCTGATCGAGGCGGTCGAGTTCCAGCAGCCGCGCCGCCGCGGCCCGGTGCGGCCGAAGCTGCGC
TATGCGCACCAGGGCGGACAGAATCCGCCCATCATCGTGATCCACGGCAACGCGCTCGACGCCGTGACGGAAACGTACAA
GCGCTATCTCGAGAATCGCTTTCGCGAAACTTTCTCGCTGACGGGCACTCCATTGCGCATAGAGTTCCGCTCGTCGACGA
ACCCGTACGCCGACAAGGACTGA

Upstream 100 bases:

>100_bases
GCGAATCAAAAAAATGAGCGGCGCGACACGTATGCCGCCGCCTGCGCGCCGACACGGCGCGAATTCGTGCTAATTTCCAT
CAAGCGCAGCCGCCCGCGGC

Downstream 100 bases:

>100_bases
GCGGCGCACGCCGCGTCGGCCGGACGGCAGAGCCGGGCGGGGTGGACAAAATCGGCTATAGTGTAGCGATTGGCGGCGGA
TCTCTTTTTCTTTGCCCCAA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MRAHRRCVSRRRHHQMKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGARPYLVVDTGGFEPVAK
DGILHEMARQTRQAVEEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVASDFYELGLGDPRAIS
AAHGDGVNDMINEALEVAYAGEPQESEEAAAARGIKIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERN
GKHYTLIDTAGLRRRGKVFEAIEKFSVVKTLQSISDANVVILLLDARQDISDQDAHIAGFVVEQGRALVVGVNKWDGLDP
HVRERTKADLARKLKFLEFAKFHFISAAEKTGIGALMRSVDDAYAAAMKKLPTPKLTRALIEAVEFQQPRRRGPVRPKLR
YAHQGGQNPPIIVIHGNALDAVTETYKRYLENRFRETFSLTGTPLRIEFRSSTNPYADKD

Sequences:

>Translated_460_residues
MRAHRRCVSRRRHHQMKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGARPYLVVDTGGFEPVAK
DGILHEMARQTRQAVEEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVASDFYELGLGDPRAIS
AAHGDGVNDMINEALEVAYAGEPQESEEAAAARGIKIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERN
GKHYTLIDTAGLRRRGKVFEAIEKFSVVKTLQSISDANVVILLLDARQDISDQDAHIAGFVVEQGRALVVGVNKWDGLDP
HVRERTKADLARKLKFLEFAKFHFISAAEKTGIGALMRSVDDAYAAAMKKLPTPKLTRALIEAVEFQQPRRRGPVRPKLR
YAHQGGQNPPIIVIHGNALDAVTETYKRYLENRFRETFSLTGTPLRIEFRSSTNPYADKD
>Mature_460_residues
MRAHRRCVSRRRHHQMKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGARPYLVVDTGGFEPVAK
DGILHEMARQTRQAVEEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVASDFYELGLGDPRAIS
AAHGDGVNDMINEALEVAYAGEPQESEEAAAARGIKIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERN
GKHYTLIDTAGLRRRGKVFEAIEKFSVVKTLQSISDANVVILLLDARQDISDQDAHIAGFVVEQGRALVVGVNKWDGLDP
HVRERTKADLARKLKFLEFAKFHFISAAEKTGIGALMRSVDDAYAAAMKKLPTPKLTRALIEAVEFQQPRRRGPVRPKLR
YAHQGGQNPPIIVIHGNALDAVTETYKRYLENRFRETFSLTGTPLRIEFRSSTNPYADKD

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=468, Percent_Identity=51.2820512820513, Blast_Score=474, Evalue=1e-135,
Organism=Escherichia coli, GI1788919, Length=124, Percent_Identity=33.8709677419355, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=38.0434782608696, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=106, Percent_Identity=37.7358490566038, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=180, Percent_Identity=32.2222222222222, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51046; Mature: 51046

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAHRRCVSRRRHHQMKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEG
CCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCC
RVGARPYLVVDTGGFEPVAKDGILHEMARQTRQAVEEADVVVFIVDGRNGLAPQDKSIAD
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHH
YLRKTGRPIFLVVNKAEGMKYTAVASDFYELGLGDPRAISAAHGDGVNDMINEALEVAYA
HHHHCCCEEEEEEECCCCCEEEHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCC
GEPQESEEAAAARGIKIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERN
CCCCCHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECC
GKHYTLIDTAGLRRRGKVFEAIEKFSVVKTLQSISDANVVILLLDARQDISDQDAHIAGF
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEE
VVEQGRALVVGVNKWDGLDPHVRERTKADLARKLKFLEFAKFHFISAAEKTGIGALMRSV
EEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDAYAAAMKKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVIHGNALD
HHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHCCCCCCCEEEEECCHHH
AVTETYKRYLENRFRETFSLTGTPLRIEFRSSTNPYADKD
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MRAHRRCVSRRRHHQMKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEG
CCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCC
RVGARPYLVVDTGGFEPVAKDGILHEMARQTRQAVEEADVVVFIVDGRNGLAPQDKSIAD
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHH
YLRKTGRPIFLVVNKAEGMKYTAVASDFYELGLGDPRAISAAHGDGVNDMINEALEVAYA
HHHHCCCEEEEEEECCCCCEEEHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCC
GEPQESEEAAAARGIKIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERN
CCCCCHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECC
GKHYTLIDTAGLRRRGKVFEAIEKFSVVKTLQSISDANVVILLLDARQDISDQDAHIAGF
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEE
VVEQGRALVVGVNKWDGLDPHVRERTKADLARKLKFLEFAKFHFISAAEKTGIGALMRSV
EEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDAYAAAMKKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVIHGNALD
HHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHCCCCCCCEEEEECCHHH
AVTETYKRYLENRFRETFSLTGTPLRIEFRSSTNPYADKD
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA