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The map label for this gene is potC [H]

Identifier: 237812378

GI number: 237812378

Start: 2103018

End: 2103812

Strand: Reverse

Name: potC [H]

Synonym: GBP346_A2126

Alternate gene names: 237812378

Gene position: 2103812-2103018 (Counterclockwise)

Preceding gene: 237812379

Following gene: 237812377

Centisome position: 51.33

GC content: 62.39

Gene sequence:

>795_bases
ATGCTTCTCGATTTCGACCGCTTGGGCGGGCTGCGCTGGGCGTTGATGGCGGTAGGCGGTGCCGTCGCTCTTTTCCTGCT
GCTGCCGATCGCGTTCATCGTCGAGTTGTCGTTCGGCGATTCGCAGTGGCTGATTTTTCCGCCGCCGGGCTGGACGCTGG
AATGGTATCGCCAGCTGTTCACCGATCCGGGCTGGCTCGGCTCTTTGCTGACCAGCTTCGAGCTCGCAGTGATCGTTACG
TTCTTTTCGGTCTTGATGGGTCTGCTCGCGTCGCTCGCACTCGTGCGAGGCGAGTTCCGCGGACGCAATGCCGTGCAGGC
GTTTTTCCTCACGCCGATGGTACTGCCCGTCGTCGTGCTCGCGGTGGCGTTGTATGCCTTCACGCTGAGGATCGGCCTGA
ACGGCACGATGGTGGGCTTCGTGATCGGCCATCTGATCATCGCGCTGCCGTTCTCGATCATTTCGATCAGCAACTCGCTC
GTGAGCTTCGATACGGCGCTCGAGGACGCCGCACTCGTCTGCGGTGCCTCGCCGCTCGAAGTGAAGCTGCGCGTGACCTT
GCCCGCGATCAAGCTAGGACTCTTCGCGGCGGCCATTTTCTCGTTCCTGGCATCGTGGGACGAAGTGGTGGTGTCGATCT
TCATGGCGAGCCCGACGTTGCAAACGCTGCCGGTGCGAATCTGGACCACGCTGCGGCAAGATTTGACGCCGATCGTCGCG
GCGGCGTCATCGTTGCTCGTGGGCTTGACGACGGTATTGATGTTGGCGGGCGCGCTATTGCGCCGCGCCCGATGA

Upstream 100 bases:

>100_bases
GGTGCCGCCGCTTTCGTGCTGCTGGCCGCGACGCTCTCGTTGTACGCGCTGCAACTCCGTTTCACCGGCAGTGCGCGCGC
AAGCTTGGGAGGACGCTGAC

Downstream 100 bases:

>100_bases
AAGAGGTGAACCAGTCATGACAGCTGCATTTTTGCAAATCCAGCGCTTGCGCAAGACCTACGACGACGTAGTCGCGATCG
ATCACGTGTCCCTGGACGTG

Product: putrescine transport system permease protein PotI

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MLLDFDRLGGLRWALMAVGGAVALFLLLPIAFIVELSFGDSQWLIFPPPGWTLEWYRQLFTDPGWLGSLLTSFELAVIVT
FFSVLMGLLASLALVRGEFRGRNAVQAFFLTPMVLPVVVLAVALYAFTLRIGLNGTMVGFVIGHLIIALPFSIISISNSL
VSFDTALEDAALVCGASPLEVKLRVTLPAIKLGLFAAAIFSFLASWDEVVVSIFMASPTLQTLPVRIWTTLRQDLTPIVA
AASSLLVGLTTVLMLAGALLRRAR

Sequences:

>Translated_264_residues
MLLDFDRLGGLRWALMAVGGAVALFLLLPIAFIVELSFGDSQWLIFPPPGWTLEWYRQLFTDPGWLGSLLTSFELAVIVT
FFSVLMGLLASLALVRGEFRGRNAVQAFFLTPMVLPVVVLAVALYAFTLRIGLNGTMVGFVIGHLIIALPFSIISISNSL
VSFDTALEDAALVCGASPLEVKLRVTLPAIKLGLFAAAIFSFLASWDEVVVSIFMASPTLQTLPVRIWTTLRQDLTPIVA
AASSLLVGLTTVLMLAGALLRRAR
>Mature_264_residues
MLLDFDRLGGLRWALMAVGGAVALFLLLPIAFIVELSFGDSQWLIFPPPGWTLEWYRQLFTDPGWLGSLLTSFELAVIVT
FFSVLMGLLASLALVRGEFRGRNAVQAFFLTPMVLPVVVLAVALYAFTLRIGLNGTMVGFVIGHLIIALPFSIISISNSL
VSFDTALEDAALVCGASPLEVKLRVTLPAIKLGLFAAAIFSFLASWDEVVVSIFMASPTLQTLPVRIWTTLRQDLTPIVA
AASSLLVGLTTVLMLAGALLRRAR

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=215, Percent_Identity=29.3023255813954, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787081, Length=231, Percent_Identity=28.1385281385281, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787571, Length=182, Percent_Identity=28.021978021978, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787714, Length=245, Percent_Identity=29.7959183673469, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28555; Mature: 28555

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]