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The map label for this gene is aprE [H]

Identifier: 237812364

GI number: 237812364

Start: 2078567

End: 2079976

Strand: Reverse

Name: aprE [H]

Synonym: GBP346_A2112

Alternate gene names: 237812364

Gene position: 2079976-2078567 (Counterclockwise)

Preceding gene: 237812365

Following gene: 237812363

Centisome position: 50.75

GC content: 63.97

Gene sequence:

>1410_bases
ATGAAGCTCATTGCGGCGATCTTCAGGCCGTTTCTGTCGCTGGCCGATGCGGTGCTCGGCTACTTCGAGCGCCACGCCTT
CGAACCGGCGTCGCCCGAGGGGCGGCAATCCTGGCGCGGCAGCGCGTTGGGGCTCGAGGAGGCGTCCATTGCACCGGCGC
GGCGTGCCGCCGCGCTGATCCCGACGGTCATGCTCGCGCTGCTGATCGTGCTCGTTCTGTGGGCCACGTTCTTCAAGATC
GACATCATTGCGGCGGGCCAGGGCAAGGTCATTCCTTCCACGACGGTTCAGCAACTCTCGACGCTGGAGGGCGGCATCGT
GCGGGAGTTGCTCGTGCGTGAAGGGCAGATCGTCAAGAAGGGGCAGCCGCTCGTTCGACTCGATCCGGTCGTGGCGCAGG
GCGCCGTGACCGAGCAGGCCGCCACGCGAGAGGGATTGATGGCCTCGATTGCGAGATTGCAGGCTGAAGCCGACGGCAAG
GCAACGCCTTTGTATCCCGCCGGCCTGAAGCCGGAAATCGTGAGCGAGGAGGAGCACGTGCGGGCGCAACGGGCGGAGGC
GCTGAATTCCACCATCGAGGTGCTGCAGCAGCAGCGCGCCGCCAAGCAGGCGGAGGCGGCCGACTACCGCGGCCGGATTC
CGCAGTACGTGAACAATCAGCATCTGTTGGATGATCAGATCCAGCGCATGTTGCCGCTGGTCGGAGTGGGGTCCGTGGCG
CCAAACGAGATCACCAATCTCCAACGCGAGCGCGGCAATCTGGCCGCACAGATCATCACGACACGCGAAGGCGCGGCACA
GGCGTCCGCGCAGATTGCCGAAGCGAGCCACAAAATCGAGGAAAAGATCTCCACCTTCCGCAGCGAGGCGCGGGAAGAGC
TGGCCAGAAAGCAGGTCCAGCTGCAGGCGCTGGAGGGCACGCTGTCCGGCAAGCAGGACATCCTCGACCGGACGTTGATC
CGCTCCCCCGTGAACGGCATCGTGAAGACGCTTTACATCACAACGATTGGCGGTGTGGCATCGCCGGGCAAGAGCGTGAT
CGACATCGTTCCGACCAACGATTCGCTGCTGATCGAGGCTCGCATCCAGCCGCAGGACATTGCCTATATCAGGGTGGGAG
ATGACGCCAAAGTCAGGATTACGGCGTTCGACTCCGGTGCGCTGGGTTCGCTGGATGCGAAGGTCGAACTGATCAGCCCG
GACAGTCAGGCCGACGAGCGCAGTGGGAGCCTCTACTACAAGGTTCAGGTTCGCACGCACAGCAGCGTGGTGGCCACGCA
GGTCGGCGACCTGAACATCTTGCCGGGGATGGTGGCCGACGTCGATGTGATCACCGGGCGTCGGACCATCATGTCCTATA
TTCTGCGGCCGATCGTACGCGGGATGAGTCGCGCGATGAGCGAGCGTTGA

Upstream 100 bases:

>100_bases
GTGGTTGCGTGGTGCTCGATGGCCCTCGGGACGACGTGCTCGCGAAGCTCTCGGGCCGCACTCAGCAAACTGCCGGCGCA
AAGGGGATGTCATCATGTCC

Downstream 100 bases:

>100_bases
CGCAGTCCGCGCCGTCGAACTTGGCTGCGGGCGGGTGATTTCGGCAGCACTGCCGGCAGGGCATTCGCTTCGCGTTTTCC
GCTTCGTGCCGACACAGCGA

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MKLIAAIFRPFLSLADAVLGYFERHAFEPASPEGRQSWRGSALGLEEASIAPARRAAALIPTVMLALLIVLVLWATFFKI
DIIAAGQGKVIPSTTVQQLSTLEGGIVRELLVREGQIVKKGQPLVRLDPVVAQGAVTEQAATREGLMASIARLQAEADGK
ATPLYPAGLKPEIVSEEEHVRAQRAEALNSTIEVLQQQRAAKQAEAADYRGRIPQYVNNQHLLDDQIQRMLPLVGVGSVA
PNEITNLQRERGNLAAQIITTREGAAQASAQIAEASHKIEEKISTFRSEAREELARKQVQLQALEGTLSGKQDILDRTLI
RSPVNGIVKTLYITTIGGVASPGKSVIDIVPTNDSLLIEARIQPQDIAYIRVGDDAKVRITAFDSGALGSLDAKVELISP
DSQADERSGSLYYKVQVRTHSSVVATQVGDLNILPGMVADVDVITGRRTIMSYILRPIVRGMSRAMSER

Sequences:

>Translated_469_residues
MKLIAAIFRPFLSLADAVLGYFERHAFEPASPEGRQSWRGSALGLEEASIAPARRAAALIPTVMLALLIVLVLWATFFKI
DIIAAGQGKVIPSTTVQQLSTLEGGIVRELLVREGQIVKKGQPLVRLDPVVAQGAVTEQAATREGLMASIARLQAEADGK
ATPLYPAGLKPEIVSEEEHVRAQRAEALNSTIEVLQQQRAAKQAEAADYRGRIPQYVNNQHLLDDQIQRMLPLVGVGSVA
PNEITNLQRERGNLAAQIITTREGAAQASAQIAEASHKIEEKISTFRSEAREELARKQVQLQALEGTLSGKQDILDRTLI
RSPVNGIVKTLYITTIGGVASPGKSVIDIVPTNDSLLIEARIQPQDIAYIRVGDDAKVRITAFDSGALGSLDAKVELISP
DSQADERSGSLYYKVQVRTHSSVVATQVGDLNILPGMVADVDVITGRRTIMSYILRPIVRGMSRAMSER
>Mature_469_residues
MKLIAAIFRPFLSLADAVLGYFERHAFEPASPEGRQSWRGSALGLEEASIAPARRAAALIPTVMLALLIVLVLWATFFKI
DIIAAGQGKVIPSTTVQQLSTLEGGIVRELLVREGQIVKKGQPLVRLDPVVAQGAVTEQAATREGLMASIARLQAEADGK
ATPLYPAGLKPEIVSEEEHVRAQRAEALNSTIEVLQQQRAAKQAEAADYRGRIPQYVNNQHLLDDQIQRMLPLVGVGSVA
PNEITNLQRERGNLAAQIITTREGAAQASAQIAEASHKIEEKISTFRSEAREELARKQVQLQALEGTLSGKQDILDRTLI
RSPVNGIVKTLYITTIGGVASPGKSVIDIVPTNDSLLIEARIQPQDIAYIRVGDDAKVRITAFDSGALGSLDAKVELISP
DSQADERSGSLYYKVQVRTHSSVVATQVGDLNILPGMVADVDVITGRRTIMSYILRPIVRGMSRAMSER

Specific function: Involved in the secretion of alkaline protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 50791; Mature: 50791

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIAAIFRPFLSLADAVLGYFERHAFEPASPEGRQSWRGSALGLEEASIAPARRAAALI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCHHCCCHHHHHHHHH
PTVMLALLIVLVLWATFFKIDIIAAGQGKVIPSTTVQQLSTLEGGIVRELLVREGQIVKK
HHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCEEEC
GQPLVRLDPVVAQGAVTEQAATREGLMASIARLQAEADGKATPLYPAGLKPEIVSEEEHV
CCCCEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHH
RAQRAEALNSTIEVLQQQRAAKQAEAADYRGRIPQYVNNQHLLDDQIQRMLPLVGVGSVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHCCCCCC
PNEITNLQRERGNLAAQIITTREGAAQASAQIAEASHKIEEKISTFRSEAREELARKQVQ
CHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQALEGTLSGKQDILDRTLIRSPVNGIVKTLYITTIGGVASPGKSVIDIVPTNDSLLIEA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEE
RIQPQDIAYIRVGDDAKVRITAFDSGALGSLDAKVELISPDSQADERSGSLYYKVQVRTH
ECCCCCEEEEEECCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEEEC
SSVVATQVGDLNILPGMVADVDVITGRRTIMSYILRPIVRGMSRAMSER
CCCHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLIAAIFRPFLSLADAVLGYFERHAFEPASPEGRQSWRGSALGLEEASIAPARRAAALI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCHHCCCHHHHHHHHH
PTVMLALLIVLVLWATFFKIDIIAAGQGKVIPSTTVQQLSTLEGGIVRELLVREGQIVKK
HHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCEEEC
GQPLVRLDPVVAQGAVTEQAATREGLMASIARLQAEADGKATPLYPAGLKPEIVSEEEHV
CCCCEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHH
RAQRAEALNSTIEVLQQQRAAKQAEAADYRGRIPQYVNNQHLLDDQIQRMLPLVGVGSVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHCCCCCC
PNEITNLQRERGNLAAQIITTREGAAQASAQIAEASHKIEEKISTFRSEAREELARKQVQ
CHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQALEGTLSGKQDILDRTLIRSPVNGIVKTLYITTIGGVASPGKSVIDIVPTNDSLLIEA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEE
RIQPQDIAYIRVGDDAKVRITAFDSGALGSLDAKVELISPDSQADERSGSLYYKVQVRTH
ECCCCCEEEEEECCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEEEC
SSVVATQVGDLNILPGMVADVDVITGRRTIMSYILRPIVRGMSRAMSER
CCCHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]