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The map label for this gene is regX3 [H]

Identifier: 237812357

GI number: 237812357

Start: 2069815

End: 2070528

Strand: Reverse

Name: regX3 [H]

Synonym: GBP346_A2105

Alternate gene names: 237812357

Gene position: 2070528-2069815 (Counterclockwise)

Preceding gene: 237812358

Following gene: 237812355

Centisome position: 50.52

GC content: 51.54

Gene sequence:

>714_bases
GTGGTCATTTATCTGATCGAGGACGATGAGATTCAGGCTCAATACTATCAGTCGATGCTTGTTGAGCACGGATGGCAGGT
CAAGTTATTGCTGGATGGGGAGCGGGCATTCCGCGAGATTCAACGGATGCCTCCCGACCTGATCATCCTGGATCGACGAT
TGCCCGATCTCGACGGCCTTGAGGTACTGATGTGGGTACGTAAGAACTACTCGAATATTCCAGTTCTCATCCTAACTAAT
GCGATCCTCGAATCCGAGGTGGTGGCCGCGTTGGAAGCAGGCGCCGACGATTACGTGATCAAGCCGCCCAGAAAACAGGA
ATTCGTTGCTCGAGTCAAGGCGTTATACCGGCGAGCAACCGAAACGAGAACGCTTTCCGAGTTGATTGAAATAGGCCCTT
ACAGGATTCAAACGTCCGAAAAGGTCGTCTATTTTCATCATGAAGCGATCACTCTGTCGCCGAAGGAATACGAGATCATC
GAATTGCTCGCGCGCAATATCGGCCAGATCGTGTCGCGTGACAAAATGGTCTACCAGGTGTGGGGGAGGCTTCCGGACGA
GGCGGCCTTTCGTACGCTCGACACGCACATTTACCGTATCAGGAGAAAATTGGAATTGACCCGCTACAACCGGTTGATAT
TGCGGGCCGTATATATGCACGGCTACAGGCTCGAATATATGGGTATCAATAATATGATGGCCCCTGCATCGTGA

Upstream 100 bases:

>100_bases
TCTAAATTCGCTGAGGATGGCCACATGAAGAAATCCAACCTTCAAACACTACTAATGCTCCGTTATATGGGGCAAAAGTT
ACAAAGGTATGAGGTGACAG

Downstream 100 bases:

>100_bases
TCCCTCTTCCCGCTCATTCTAGGGGGGCAGCCAGAATTCGTGAAATTGTCACCAAAATGGCTTAATCCACTGATTCAAAA
AAGAAATCGGTACTTGAATC

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MVIYLIEDDEIQAQYYQSMLVEHGWQVKLLLDGERAFREIQRMPPDLIILDRRLPDLDGLEVLMWVRKNYSNIPVLILTN
AILESEVVAALEAGADDYVIKPPRKQEFVARVKALYRRATETRTLSELIEIGPYRIQTSEKVVYFHHEAITLSPKEYEII
ELLARNIGQIVSRDKMVYQVWGRLPDEAAFRTLDTHIYRIRRKLELTRYNRLILRAVYMHGYRLEYMGINNMMAPAS

Sequences:

>Translated_237_residues
MVIYLIEDDEIQAQYYQSMLVEHGWQVKLLLDGERAFREIQRMPPDLIILDRRLPDLDGLEVLMWVRKNYSNIPVLILTN
AILESEVVAALEAGADDYVIKPPRKQEFVARVKALYRRATETRTLSELIEIGPYRIQTSEKVVYFHHEAITLSPKEYEII
ELLARNIGQIVSRDKMVYQVWGRLPDEAAFRTLDTHIYRIRRKLELTRYNRLILRAVYMHGYRLEYMGINNMMAPAS
>Mature_237_residues
MVIYLIEDDEIQAQYYQSMLVEHGWQVKLLLDGERAFREIQRMPPDLIILDRRLPDLDGLEVLMWVRKNYSNIPVLILTN
AILESEVVAALEAGADDYVIKPPRKQEFVARVKALYRRATETRTLSELIEIGPYRIQTSEKVVYFHHEAITLSPKEYEII
ELLARNIGQIVSRDKMVYQVWGRLPDEAAFRTLDTHIYRIRRKLELTRYNRLILRAVYMHGYRLEYMGINNMMAPAS

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=33.6363636363636, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=32.8947368421053, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=33.4821428571429, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790860, Length=203, Percent_Identity=32.0197044334975, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786911, Length=180, Percent_Identity=31.6666666666667, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=29.9559471365639, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=28.8888888888889, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=31.25, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI87082012, Length=205, Percent_Identity=31.219512195122, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=28, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787229, Length=208, Percent_Identity=31.25, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI145693140, Length=213, Percent_Identity=29.5774647887324, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI2367329, Length=210, Percent_Identity=29.5238095238095, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=26.8398268398268, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27913; Mature: 27913

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIYLIEDDEIQAQYYQSMLVEHGWQVKLLLDGERAFREIQRMPPDLIILDRRLPDLDGL
CEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEEEECCCCCCCHH
EVLMWVRKNYSNIPVLILTNAILESEVVAALEAGADDYVIKPPRKQEFVARVKALYRRAT
HHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHH
ETRTLSELIEIGPYRIQTSEKVVYFHHEAITLSPKEYEIIELLARNIGQIVSRDKMVYQV
HHHHHHHHHHCCCEEEECCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
WGRLPDEAAFRTLDTHIYRIRRKLELTRYNRLILRAVYMHGYRLEYMGINNMMAPAS
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MVIYLIEDDEIQAQYYQSMLVEHGWQVKLLLDGERAFREIQRMPPDLIILDRRLPDLDGL
CEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEEEECCCCCCCHH
EVLMWVRKNYSNIPVLILTNAILESEVVAALEAGADDYVIKPPRKQEFVARVKALYRRAT
HHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHH
ETRTLSELIEIGPYRIQTSEKVVYFHHEAITLSPKEYEIIELLARNIGQIVSRDKMVYQV
HHHHHHHHHHCCCEEEECCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
WGRLPDEAAFRTLDTHIYRIRRKLELTRYNRLILRAVYMHGYRLEYMGINNMMAPAS
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA