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The map label for this gene is lgrC [H]

Identifier: 237812308

GI number: 237812308

Start: 2025336

End: 2025740

Strand: Reverse

Name: lgrC [H]

Synonym: GBP346_A2056

Alternate gene names: 237812308

Gene position: 2025740-2025336 (Counterclockwise)

Preceding gene: 237812309

Following gene: 237812307

Centisome position: 49.43

GC content: 66.67

Gene sequence:

>405_bases
ATGGTGCCTGTATCGATCGCGGTGGTCGATCGGCTACCGCTTACGCGGAGCGGCAAAGTCGACCGGACGGCGGCGATTCG
GCTGGCAGGCGAGGGGCAGGTGGCCGAGCCGACAGTCGCGGCTAGCCCGCTCGAGGCGCTGGTCGCCATGCAATGGGCCG
AATTGCTGACGGTCAGCTCGATCGGCGTCGAGCAGGACTTCTTCGCGGCTGGCGGGCATTCGCTGCTCGCGATGCGCGCG
CTGTCGCACCTCGGCGCCCGAGTTGCCGGGCTCTTCGGCGCGTACGGTGACGAGGGCGTCGAGGATGTTCATCTGGTTTC
GTCGTTGCTGGCGTCGCTGATTGTGGCGGTAGCGGTTGTGTGTGGCGCGAATCGACTGTTCCGGCGTCCGAGTCGTGGGA
ATTGA

Upstream 100 bases:

>100_bases
GCCCGGCACGCGCGAAGTCGACGGCGGCAAATCAGGTGTGGAGTTTGGACTTCGTCGCCGACCAGCTTTCGAGCAGCCGG
GGGAGGCCGCGCACTGACAT

Downstream 100 bases:

>100_bases
AGATGCAGCTTGAATTGCTGGAGCGGCCGTATCTGTCGGCGCAAGAGCTGGCCGACGTGGCTCGGGATATAGGAATCTCT
ACTGGGCGATCCGCAATACT

Product: putative non-ribosomal peptide synthetase

Products: NA

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MVPVSIAVVDRLPLTRSGKVDRTAAIRLAGEGQVAEPTVAASPLEALVAMQWAELLTVSSIGVEQDFFAAGGHSLLAMRA
LSHLGARVAGLFGAYGDEGVEDVHLVSSLLASLIVAVAVVCGANRLFRRPSRGN

Sequences:

>Translated_134_residues
MVPVSIAVVDRLPLTRSGKVDRTAAIRLAGEGQVAEPTVAASPLEALVAMQWAELLTVSSIGVEQDFFAAGGHSLLAMRA
LSHLGARVAGLFGAYGDEGVEDVHLVSSLLASLIVAVAVVCGANRLFRRPSRGN
>Mature_134_residues
MVPVSIAVVDRLPLTRSGKVDRTAAIRLAGEGQVAEPTVAASPLEALVAMQWAELLTVSSIGVEQDFFAAGGHSLLAMRA
LSHLGARVAGLFGAYGDEGVEDVHLVSSLLASLIVAVAVVCGANRLFRRPSRGN

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: NA

Molecular weight: Translated: 13889; Mature: 13889

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPVSIAVVDRLPLTRSGKVDRTAAIRLAGEGQVAEPTVAASPLEALVAMQWAELLTVSS
CCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IGVEQDFFAAGGHSLLAMRALSHLGARVAGLFGAYGDEGVEDVHLVSSLLASLIVAVAVV
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
CGANRLFRRPSRGN
HCCHHHHCCCCCCC
>Mature Secondary Structure
MVPVSIAVVDRLPLTRSGKVDRTAAIRLAGEGQVAEPTVAASPLEALVAMQWAELLTVSS
CCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IGVEQDFFAAGGHSLLAMRALSHLGARVAGLFGAYGDEGVEDVHLVSSLLASLIVAVAVV
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
CGANRLFRRPSRGN
HCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA