Click here to switch to the map view.

The map label for this gene is arnA [H]

Identifier: 237812293

GI number: 237812293

Start: 1989601

End: 1990419

Strand: Direct

Name: arnA [H]

Synonym: GBP346_A2041

Alternate gene names: 237812293

Gene position: 1989601-1990419 (Clockwise)

Preceding gene: 237812292

Following gene: 237812294

Centisome position: 48.54

GC content: 62.03

Gene sequence:

>819_bases
ATGAATGACATGACTCGCGAGAAGGTCCTGCTCTGCATCGACAACGTCGCAGGGCTGGCGGTGCTCAAGTACCTGGCCGA
CAGGCCGAGCGTCGAGGTCGTCGGCGCGATCGTCCATCCGCAAGCGAATGCGACGCACCTCGACGAAATCGTCGAGGTGT
GCGCACGAAACGGCATTGCGCCGATCGACATCCTCGAGGCGCGCGCGCGCTTCGACGAGCTGATCGCGCCGCTCGCGCCG
GACTTCATCGTTTCGATCTACTTCGACTATATCCTCGACGATCGCTTCATCGAGCTGCCGGCGAAGGATTCGATCAATCT
GCATCCGGGCTACCTGCCGTACAACAAGGGCTTCTATTACTACGCGTGGGCCGTGCTCGACGGCACGCCGGCGGGCGTCA
GCATCCACCGGATCGTGTCGGCGGTCGACGCCGGGCCGATCATCAGCCAGAAGCGCGTGCTGATCGACGGCACGGACACG
GGCGACGTCATCTACGACAAGCACATGGACGCGTCGGTCGAGCTGTTCCGGACCACCTGGCCGAGCATCGAAAGCGGCAC
GTATCAGTTGTTCCGGCAGCGGCACAAGGGCACGCGCAAGAAGATCACCGAAACCAACGAGGCGATGGAGATCGATCCGA
ACGCGACCTATGTCGCGCGCGAGCTCATCGATCTGCTGCGCGTGTTCTGCTTTCGCGGCAGCGGCGGCTGCGTGATGAAG
ATCGACGGCAAGAAATACAGCATCGGCATCGAATTCTCGGAACTGGCCGACAACGTCAACCAGATTCGCGGCAAGCGCGA
CAACTACCTCGTCGGCTAG

Upstream 100 bases:

>100_bases
TTCGGCATTTGCTACGTTCTCAAGTATCGCGGCGCGCACTGCTGACTGATCCCCCAACGGCTCGACGCGCTTTCGTGCGC
GATCCGAATAGGATTCCTAC

Downstream 100 bases:

>100_bases
TCGGCGAGGCGGCGAACCCATCCATCACGGAAGATCGGACATGAAACCCAAACACATTCTCCTCGCTTATTCCGGCGGCC
TCGACACGTCCACCGCGCTG

Product: nonribosomal peptide synthetase

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MNDMTREKVLLCIDNVAGLAVLKYLADRPSVEVVGAIVHPQANATHLDEIVEVCARNGIAPIDILEARARFDELIAPLAP
DFIVSIYFDYILDDRFIELPAKDSINLHPGYLPYNKGFYYYAWAVLDGTPAGVSIHRIVSAVDAGPIISQKRVLIDGTDT
GDVIYDKHMDASVELFRTTWPSIESGTYQLFRQRHKGTRKKITETNEAMEIDPNATYVARELIDLLRVFCFRGSGGCVMK
IDGKKYSIGIEFSELADNVNQIRGKRDNYLVG

Sequences:

>Translated_272_residues
MNDMTREKVLLCIDNVAGLAVLKYLADRPSVEVVGAIVHPQANATHLDEIVEVCARNGIAPIDILEARARFDELIAPLAP
DFIVSIYFDYILDDRFIELPAKDSINLHPGYLPYNKGFYYYAWAVLDGTPAGVSIHRIVSAVDAGPIISQKRVLIDGTDT
GDVIYDKHMDASVELFRTTWPSIESGTYQLFRQRHKGTRKKITETNEAMEIDPNATYVARELIDLLRVFCFRGSGGCVMK
IDGKKYSIGIEFSELADNVNQIRGKRDNYLVG
>Mature_272_residues
MNDMTREKVLLCIDNVAGLAVLKYLADRPSVEVVGAIVHPQANATHLDEIVEVCARNGIAPIDILEARARFDELIAPLAP
DFIVSIYFDYILDDRFIELPAKDSINLHPGYLPYNKGFYYYAWAVLDGTPAGVSIHRIVSAVDAGPIISQKRVLIDGTDT
GDVIYDKHMDASVELFRTTWPSIESGTYQLFRQRHKGTRKKITETNEAMEIDPNATYVARELIDLLRVFCFRGSGGCVMK
IDGKKYSIGIEFSELADNVNQIRGKRDNYLVG

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788589, Length=123, Percent_Identity=34.1463414634146, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 30431; Mature: 30431

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDMTREKVLLCIDNVAGLAVLKYLADRPSVEVVGAIVHPQANATHLDEIVEVCARNGIA
CCCCCHHHEEEEECCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCC
PIDILEARARFDELIAPLAPDFIVSIYFDYILDDRFIELPAKDSINLHPGYLPYNKGFYY
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCEEE
YAWAVLDGTPAGVSIHRIVSAVDAGPIISQKRVLIDGTDTGDVIYDKHMDASVELFRTTW
EEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEECCCCCHHHEEECCC
PSIESGTYQLFRQRHKGTRKKITETNEAMEIDPNATYVARELIDLLRVFCFRGSGGCVMK
CCCCCHHHHHHHHHHCCHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEE
IDGKKYSIGIEFSELADNVNQIRGKRDNYLVG
ECCCEEEEECCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNDMTREKVLLCIDNVAGLAVLKYLADRPSVEVVGAIVHPQANATHLDEIVEVCARNGIA
CCCCCHHHEEEEECCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCC
PIDILEARARFDELIAPLAPDFIVSIYFDYILDDRFIELPAKDSINLHPGYLPYNKGFYY
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCEEE
YAWAVLDGTPAGVSIHRIVSAVDAGPIISQKRVLIDGTDTGDVIYDKHMDASVELFRTTW
EEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEECCCCCHHHEEECCC
PSIESGTYQLFRQRHKGTRKKITETNEAMEIDPNATYVARELIDLLRVFCFRGSGGCVMK
CCCCCHHHHHHHHHHCCHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEE
IDGKKYSIGIEFSELADNVNQIRGKRDNYLVG
ECCCEEEEECCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA