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The map label for this gene is ycaN [H]

Identifier: 237812258

GI number: 237812258

Start: 1957830

End: 1958750

Strand: Reverse

Name: ycaN [H]

Synonym: GBP346_A2006

Alternate gene names: 237812258

Gene position: 1958750-1957830 (Counterclockwise)

Preceding gene: 237812261

Following gene: 237812257

Centisome position: 47.79

GC content: 70.58

Gene sequence:

>921_bases
ATGACGATGAAACGCGATCCGCTCGGCGGCCTGCACGTATTCATGAGCGTCGTCACGCACGGCAATTTCACGCGTGCGGC
GGCGGCGCTCGGCTTGACGCCGGCCGCGGTGAGCCTGGCGATCGGGCAACTCGAAAGCGAGCTGAAAGTGAAGCTCTTCA
GCCGCAGCACGCGCGGCGTGAGCCTGACGGAAGCCGGCCAGCGCTATTACGACGCAACGGCGCAGCCCTACCGGCAGGTC
GTCGACGCGCGCGACGCGCTGAACGACGCGCGCGACGAACCCGAGGGCCTGTTGCGGATCAGCGCGCTGCACCTCGCGAA
ATCGGTCGTGACGGCCGACGTGCTCGCCGAGTTCTTCCGCCGCTACCCGAAGGTGAGCGTCGAGATCCGCTACGAGGATC
ATCTCGTCGACATCGTCAAGGAACGCCTCGACGCCGGAATCCGCCTCGCGGACCGGCTGCAGCCCGGGATGGTGGGCGTG
AAGATCGCGCCCGCGCTCACGTGCGCGCTCGTCGCGACGCCCGGCTATCTCGCGCAGCACGGCGTGCCGGCGAAGCTCGC
CGATCTCGCGCGGCACATGTGCATCCGCTTTCGCTTTCCGAAGAGCGGCCGCCTGCACAAATGGCCGCTGCGCGACGGCC
GCCGCGACGTCGAGCTCGACGTCGCCGGCCGCTTCGTCAGCACCGATACGGGCGCGGTGATCGACGCCGCGCGCGCGGGC
GCGGGCATCGCGTTCGTGTTCATGCGCGAGCGCATCGAGGACGACCTGCGCCGCGGCACGCTGCGCGAGGTGCTGCCGGG
CGCGTGCCGGACGCTGCCGCCGATGTGGCTCTACTACGCGAACCGCAAGCACGTGCCGCCGAAGCTGCGCGCGTTCATCG
CGGTGCTGCGCGAGCACGCGGCGGCCGACGCGCGGCGCTGA

Upstream 100 bases:

>100_bases
CATCGGCGGCTCCTTGTGCGGTTCGACTGCGAGCCAGTGTAGGGACCGGCGGTATCTGAGAGAATCGGTATTCCGCTCAC
AAACGTATCAAGTTTTTCTA

Downstream 100 bases:

>100_bases
CGGCCCGCCCGCGCGTTTCCGGCCGAGCGTTTCCCGGCCGCGCCGCCGTCGCGCCGCTTCGCCCGCGCCCGGAGCGCGGC
CGGGAGGCGGCCGGGTTCGC

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTMKRDPLGGLHVFMSVVTHGNFTRAAAALGLTPAAVSLAIGQLESELKVKLFSRSTRGVSLTEAGQRYYDATAQPYRQV
VDARDALNDARDEPEGLLRISALHLAKSVVTADVLAEFFRRYPKVSVEIRYEDHLVDIVKERLDAGIRLADRLQPGMVGV
KIAPALTCALVATPGYLAQHGVPAKLADLARHMCIRFRFPKSGRLHKWPLRDGRRDVELDVAGRFVSTDTGAVIDAARAG
AGIAFVFMRERIEDDLRRGTLREVLPGACRTLPPMWLYYANRKHVPPKLRAFIAVLREHAAADARR

Sequences:

>Translated_306_residues
MTMKRDPLGGLHVFMSVVTHGNFTRAAAALGLTPAAVSLAIGQLESELKVKLFSRSTRGVSLTEAGQRYYDATAQPYRQV
VDARDALNDARDEPEGLLRISALHLAKSVVTADVLAEFFRRYPKVSVEIRYEDHLVDIVKERLDAGIRLADRLQPGMVGV
KIAPALTCALVATPGYLAQHGVPAKLADLARHMCIRFRFPKSGRLHKWPLRDGRRDVELDVAGRFVSTDTGAVIDAARAG
AGIAFVFMRERIEDDLRRGTLREVLPGACRTLPPMWLYYANRKHVPPKLRAFIAVLREHAAADARR
>Mature_305_residues
TMKRDPLGGLHVFMSVVTHGNFTRAAAALGLTPAAVSLAIGQLESELKVKLFSRSTRGVSLTEAGQRYYDATAQPYRQVV
DARDALNDARDEPEGLLRISALHLAKSVVTADVLAEFFRRYPKVSVEIRYEDHLVDIVKERLDAGIRLADRLQPGMVGVK
IAPALTCALVATPGYLAQHGVPAKLADLARHMCIRFRFPKSGRLHKWPLRDGRRDVELDVAGRFVSTDTGAVIDAARAGA
GIAFVFMRERIEDDLRRGTLREVLPGACRTLPPMWLYYANRKHVPPKLRAFIAVLREHAAADARR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=302, Percent_Identity=34.7682119205298, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1787589, Length=299, Percent_Identity=29.7658862876254, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786401, Length=302, Percent_Identity=31.1258278145695, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=32.5423728813559, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=30.4498269896194, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=31.1643835616438, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI145693193, Length=296, Percent_Identity=27.3648648648649, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI157672245, Length=173, Percent_Identity=30.635838150289, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788706, Length=303, Percent_Identity=26.4026402640264, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787806, Length=122, Percent_Identity=35.2459016393443, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789173, Length=195, Percent_Identity=31.7948717948718, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33882; Mature: 33751

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMKRDPLGGLHVFMSVVTHGNFTRAAAALGLTPAAVSLAIGQLESELKVKLFSRSTRGV
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
SLTEAGQRYYDATAQPYRQVVDARDALNDARDEPEGLLRISALHLAKSVVTADVLAEFFR
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYPKVSVEIRYEDHLVDIVKERLDAGIRLADRLQPGMVGVKIAPALTCALVATPGYLAQH
HCCCEEEEEEEHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEHHHHHHHHHHCCCCHHHHC
GVPAKLADLARHMCIRFRFPKSGRLHKWPLRDGRRDVELDVAGRFVSTDTGAVIDAARAG
CCCHHHHHHHHHHHHEEECCCCCCEEECCCCCCCCCEEEEECCEEECCCCCHHHHHHHCC
AGIAFVFMRERIEDDLRRGTLREVLPGACRTLPPMWLYYANRKHVPPKLRAFIAVLREHA
CCHHHHHHHHHHHHHHHHCHHHHHCCHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHH
AADARR
HCCCCC
>Mature Secondary Structure 
TMKRDPLGGLHVFMSVVTHGNFTRAAAALGLTPAAVSLAIGQLESELKVKLFSRSTRGV
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
SLTEAGQRYYDATAQPYRQVVDARDALNDARDEPEGLLRISALHLAKSVVTADVLAEFFR
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYPKVSVEIRYEDHLVDIVKERLDAGIRLADRLQPGMVGVKIAPALTCALVATPGYLAQH
HCCCEEEEEEEHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEHHHHHHHHHHCCCCHHHHC
GVPAKLADLARHMCIRFRFPKSGRLHKWPLRDGRRDVELDVAGRFVSTDTGAVIDAARAG
CCCHHHHHHHHHHHHEEECCCCCCEEECCCCCCCCCEEEEECCEEECCCCCHHHHHHHCC
AGIAFVFMRERIEDDLRRGTLREVLPGACRTLPPMWLYYANRKHVPPKLRAFIAVLREHA
CCHHHHHHHHHHHHHHHHCHHHHHCCHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHH
AADARR
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]