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The map label for this gene is cobK [H]

Identifier: 237812248

GI number: 237812248

Start: 1948702

End: 1949436

Strand: Direct

Name: cobK [H]

Synonym: GBP346_A1996

Alternate gene names: 237812248

Gene position: 1948702-1949436 (Clockwise)

Preceding gene: 237812247

Following gene: 237812249

Centisome position: 47.55

GC content: 78.23

Gene sequence:

>735_bases
ATGAGCGTGCGCCGCGTGTTGCTGCTCGGCGGCACGGGCGACGCGCTGCGCACCGCGCGCGCGCTCGCGCCGCACGACGT
GTACAGCCTCGCCGGCCTCGGCCGGGTGCCCGACGATCTCGCGTGCGGCGTGCGGGTCGGCGGCTTCGGCGGCGCCGACG
GGCTCGCGCGCTACCTGCGCGAGCACGCGGTCGCGCTCGTCGTCGACGCGACGCACCCGTTCGCCGCGCGGATCAGCGCG
AACGCGGCCGCCGCCTGCCGCGCGGCGGGCGTGCCGTACTGGGCGCTGCGCCGCGCGCCGTGGCGGCCGCGGCCGGGCGA
CGACTGGCGCGGCGTCGCCGATTGGGCGGGCGTGCTCGCCGCGATCGCGCCGTTCGCGCGGCCGCTTTTCACGCTCGGGC
GCGAACCGCTCGCGCATCTCGACGAGATTGCGCCGCACCAGCACTGGCTCGTGCGCTGCCTCGACGCGCATGCCGGCAAC
GCGCGCGCGCACGTGCTCGCCGCGCGCGGGCCGTTTTCGCTCGAAGGCGAGCGCGCGCTGTTCGCGGCGGCGGCGATCGA
CGTCGTCGTCAGCAAGAACAGCGGCGGGGCGGCGACGGAGGCGAAACTCGACGTCGCGCGCGAGCGGCGCGTGCCGGTCG
TGATGGTCGAGCGGCCGGCGCTGCCCGACGCGGATCGCGAGTTCGGCGCGACGGCCGCGCTCGTCGACGCGCTGCGCGCG
TGGCGCGCGCCGTGA

Upstream 100 bases:

>100_bases
GCGCGCATGCGCGCCGCGTGGCGCGCGACATCGTGCCCGGCGAGGTCGACGTCGAGACGCTCGCGATCGACCGCGAGGGC
CGCATCGTCGGCGTCGCGCC

Downstream 100 bases:

>100_bases
CGGGCCGCGCGCGGATGCGCGGGCGTGAGACGGGAGAGCGGCGCGACGTCGCCCGCCCGTGGTCGCGCGTGCCGCGTCGC
GCGCCGTGCGGCGCGCGGTG

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSVRRVLLLGGTGDALRTARALAPHDVYSLAGLGRVPDDLACGVRVGGFGGADGLARYLREHAVALVVDATHPFAARISA
NAAAACRAAGVPYWALRRAPWRPRPGDDWRGVADWAGVLAAIAPFARPLFTLGREPLAHLDEIAPHQHWLVRCLDAHAGN
ARAHVLAARGPFSLEGERALFAAAAIDVVVSKNSGGAATEAKLDVARERRVPVVMVERPALPDADREFGATAALVDALRA
WRAP

Sequences:

>Translated_244_residues
MSVRRVLLLGGTGDALRTARALAPHDVYSLAGLGRVPDDLACGVRVGGFGGADGLARYLREHAVALVVDATHPFAARISA
NAAAACRAAGVPYWALRRAPWRPRPGDDWRGVADWAGVLAAIAPFARPLFTLGREPLAHLDEIAPHQHWLVRCLDAHAGN
ARAHVLAARGPFSLEGERALFAAAAIDVVVSKNSGGAATEAKLDVARERRVPVVMVERPALPDADREFGATAALVDALRA
WRAP
>Mature_243_residues
SVRRVLLLGGTGDALRTARALAPHDVYSLAGLGRVPDDLACGVRVGGFGGADGLARYLREHAVALVVDATHPFAARISAN
AAAACRAAGVPYWALRRAPWRPRPGDDWRGVADWAGVLAAIAPFARPLFTLGREPLAHLDEIAPHQHWLVRCLDAHAGNA
RAHVLAARGPFSLEGERALFAAAAIDVVVSKNSGGAATEAKLDVARERRVPVVMVERPALPDADREFGATAALVDALRAW
RAP

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 25808; Mature: 25677

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRRVLLLGGTGDALRTARALAPHDVYSLAGLGRVPDDLACGVRVGGFGGADGLARYLR
CCCEEEEEECCCCHHHHHHHHCCCHHHHHHHCCCCCCCHHHCCEEECCCCCHHHHHHHHH
EHAVALVVDATHPFAARISANAAAACRAAGVPYWALRRAPWRPRPGDDWRGVADWAGVLA
HCCEEEEEECCCCCHHHHCCCHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHH
AIAPFARPLFTLGREPLAHLDEIAPHQHWLVRCLDAHAGNARAHVLAARGPFSLEGERAL
HHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHH
FAAAAIDVVVSKNSGGAATEAKLDVARERRVPVVMVERPALPDADREFGATAALVDALRA
HHHHEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
WRAP
HCCC
>Mature Secondary Structure 
SVRRVLLLGGTGDALRTARALAPHDVYSLAGLGRVPDDLACGVRVGGFGGADGLARYLR
CCEEEEEECCCCHHHHHHHHCCCHHHHHHHCCCCCCCHHHCCEEECCCCCHHHHHHHHH
EHAVALVVDATHPFAARISANAAAACRAAGVPYWALRRAPWRPRPGDDWRGVADWAGVLA
HCCEEEEEECCCCCHHHHCCCHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHH
AIAPFARPLFTLGREPLAHLDEIAPHQHWLVRCLDAHAGNARAHVLAARGPFSLEGERAL
HHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHH
FAAAAIDVVVSKNSGGAATEAKLDVARERRVPVVMVERPALPDADREFGATAALVDALRA
HHHHEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
WRAP
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732193 [H]