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The map label for this gene is cobJ [H]

Identifier: 237812241

GI number: 237812241

Start: 1941345

End: 1943195

Strand: Reverse

Name: cobJ [H]

Synonym: GBP346_A1988

Alternate gene names: 237812241

Gene position: 1943195-1941345 (Counterclockwise)

Preceding gene: 237812242

Following gene: 237812240

Centisome position: 47.41

GC content: 76.77

Gene sequence:

>1851_bases
ATGACCGCCGCGCCCGCGATCGTGATACTCGGGCCGGGCGCGCTCGAGACCGCGCGCCGGATCCAGGCGCGCTTCGACGG
CGCGCGGGTGCACGCGCTCGCCGGGCGCGCCGAGGCGGACCTCGCGTTCGCCGAGCTCGGCCCGCATCTGCGCGAGCTGT
ATGCGCGCGGCGCGCCGATCGTCGCGCTGTTCGCGGCCGGCATCGCGATTCGCTGCGTCGCGCCGTGCCTCGCCGACAAG
GGCGCGGAGCCGCCCGTGCTCGCCGTCGCCGAGGACGGCAGCGCGGTCGTGCCGCTGTTGGGCGGCCTCGCGGGCGCCAA
CGCGCTCGCGCGCGAGATCGCCGACGCGCTCGGCGTCGCGGCCGCGATCACGACGAGCGGCGAACTGCGCTTCGGCGCGT
GCATGCTGAACCCGCCCGAAGGCTACGCGCTCGCCGATCTCGACGCGGGCAAGCGCTTCGTGTCCGATCTGCTCGCGGGC
GAAAGCACGCGCGTCGAAGGCGATGCGCGCTGGCTCGACGATGTCGCGCTGCCGCGCGACGCGCACGCGGCGCGCGTGAT
CCGCGTCACGCCGCATGCGTCGCGTGGCGACGCGCACGCGTTGCTGATCCATCCGCGCAGCGTCGTCGTCGCGTTGGGCG
ATGGCGATGGGGATATCGACGGCGAGGGCCTGCGCGACGACGCGCGCAGCGTCTCGGCGCCCGATGCCACCGGTCGCGCC
CGCGCGAACGCGGCGGCGCCCGCGCGCGCCGCGTCGCCGGATCTGCCGCCGCTTGCCGCGCGCATCGCCGCCGCGCTCGC
CGCGCATGATCTCGCGCCGCTCGCGCTCGCGGCCGTCGTCGCGCCCGCGCGGCGCATCGCCGAGCACGCGCTGACCGACG
CGGCGCGCGCGCTGCGCGCGCCGTTGCGCTTCGTCGAAACGAACGCGCGCGACGCCGCCGGCGTGCTCGACGCCGCGTTG
CCCGCGGCGCTCGCGCCGCGCGTCGACGCCTCGCGCGCCGCGGCGGGCTCGCCGCGAACGACGCCGCCCGAGCCGCGCGA
CGTCGCGATCGCCGTCGCCCGCGCGCCCGTCGACGCCGATGCGCTCGGCATCGCGCGCGGCCGCCTGACGGTGCTCGGCC
TCGGCCCCGGCCGCGCGGACCTGATGACCCCCGCCGCGCGCGCGGCGCTCGCCGACGCGACCGACATCGTCGGCTACGCG
ACCTACGTGAACATGGCGGGCCCGTTGCGCGCCGATCAGCAACTGCACGTATCCGACAACCGCGAGGAGCTGCAGCGCGC
GCGCCACGCGTTCGAGCTCGCCGCGCGGGGCCGGCGCGTCGCGGTCGTGTCCTCGGGCGACCCCGGCGTGTTCGCGATGG
CGGCCGCCGTGCTCGAGGCGCTCGACGGCGCCGACGACGCGCGCTGGGCGGCCGTCGAGCTCGACGTCGTGCCCGGCGTG
TCGGCCGCGCTCGCGACGGCGGCCGAAGCCGGCGCGCCGCTCGGCCACGATTTCTGCCTGATCTCGCTGTCGGACAACCT
GAAGCCGTGGGCGATCATCGAAAAACGCATCGATCACGCGGCGGCCGCCGATTTCGCGCTCGCGTTCTACAACCCGGTGT
CGCGCGCGCGGCCCGTGCAGTTCGATCGCGCGCTCGACATCGTGCGCCGGCATCGCGCGCCGGAGACGGTCGTCGTGCTC
GGCCGCGACATCGGCCGCCCCGGCGCGACGCTCGCGACGACGACGCTCGCCGCGCTGTCCGCGCAGCAGGTCGACATGCG
CACGATGGTGATCGTCGGCTCGTCGACGACGCGCCGCGTCGCGCGCGACGGCGCGCGCGACTGGGTGTATACGCCGCGCT
GGTATCGCTGA

Upstream 100 bases:

>100_bases
CGACGATGGCCGCGCAGCGGATCGTGCCGCTCGCGGACGTCGATCCGATGGCGTCGCCGTATTTTTCGCTGCTCGTCGTG
CCGGGGGAAAAATGGCAAGG

Downstream 100 bases:

>100_bases
TATCGCGGCCGCCGAAGCGAGGCGACGCACGGCGCGTCGTCCCGCTTCGCCGGCAACGGGCGCGCCGCGCACCGAGCGCG
CCCGCTGCGCGCTTGCGCGC

Product: precorrin-3B C(17)-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase; Precorrin-3 methyltransferase [H]

Number of amino acids: Translated: 616; Mature: 615

Protein sequence:

>616_residues
MTAAPAIVILGPGALETARRIQARFDGARVHALAGRAEADLAFAELGPHLRELYARGAPIVALFAAGIAIRCVAPCLADK
GAEPPVLAVAEDGSAVVPLLGGLAGANALAREIADALGVAAAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDLLAG
ESTRVEGDARWLDDVALPRDAHAARVIRVTPHASRGDAHALLIHPRSVVVALGDGDGDIDGEGLRDDARSVSAPDATGRA
RANAAAPARAASPDLPPLAARIAAALAAHDLAPLALAAVVAPARRIAEHALTDAARALRAPLRFVETNARDAAGVLDAAL
PAALAPRVDASRAAAGSPRTTPPEPRDVAIAVARAPVDADALGIARGRLTVLGLGPGRADLMTPAARAALADATDIVGYA
TYVNMAGPLRADQQLHVSDNREELQRARHAFELAARGRRVAVVSSGDPGVFAMAAAVLEALDGADDARWAAVELDVVPGV
SAALATAAEAGAPLGHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQFDRALDIVRRHRAPETVVVL
GRDIGRPGATLATTTLAALSAQQVDMRTMVIVGSSTTRRVARDGARDWVYTPRWYR

Sequences:

>Translated_616_residues
MTAAPAIVILGPGALETARRIQARFDGARVHALAGRAEADLAFAELGPHLRELYARGAPIVALFAAGIAIRCVAPCLADK
GAEPPVLAVAEDGSAVVPLLGGLAGANALAREIADALGVAAAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDLLAG
ESTRVEGDARWLDDVALPRDAHAARVIRVTPHASRGDAHALLIHPRSVVVALGDGDGDIDGEGLRDDARSVSAPDATGRA
RANAAAPARAASPDLPPLAARIAAALAAHDLAPLALAAVVAPARRIAEHALTDAARALRAPLRFVETNARDAAGVLDAAL
PAALAPRVDASRAAAGSPRTTPPEPRDVAIAVARAPVDADALGIARGRLTVLGLGPGRADLMTPAARAALADATDIVGYA
TYVNMAGPLRADQQLHVSDNREELQRARHAFELAARGRRVAVVSSGDPGVFAMAAAVLEALDGADDARWAAVELDVVPGV
SAALATAAEAGAPLGHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQFDRALDIVRRHRAPETVVVL
GRDIGRPGATLATTTLAALSAQQVDMRTMVIVGSSTTRRVARDGARDWVYTPRWYR
>Mature_615_residues
TAAPAIVILGPGALETARRIQARFDGARVHALAGRAEADLAFAELGPHLRELYARGAPIVALFAAGIAIRCVAPCLADKG
AEPPVLAVAEDGSAVVPLLGGLAGANALAREIADALGVAAAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDLLAGE
STRVEGDARWLDDVALPRDAHAARVIRVTPHASRGDAHALLIHPRSVVVALGDGDGDIDGEGLRDDARSVSAPDATGRAR
ANAAAPARAASPDLPPLAARIAAALAAHDLAPLALAAVVAPARRIAEHALTDAARALRAPLRFVETNARDAAGVLDAALP
AALAPRVDASRAAAGSPRTTPPEPRDVAIAVARAPVDADALGIARGRLTVLGLGPGRADLMTPAARAALADATDIVGYAT
YVNMAGPLRADQQLHVSDNREELQRARHAFELAARGRRVAVVSSGDPGVFAMAAAVLEALDGADDARWAAVELDVVPGVS
AALATAAEAGAPLGHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQFDRALDIVRRHRAPETVVVLG
RDIGRPGATLATTTLAALSAQQVDMRTMVIVGSSTTRRVARDGARDWVYTPRWYR

Specific function: Methyltransferase that catalyzes the methylation of C-17 in precorrin-3B to form precorrin-4 [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006363 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.131 [H]

Molecular weight: Translated: 63660; Mature: 63529

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAPAIVILGPGALETARRIQARFDGARVHALAGRAEADLAFAELGPHLRELYARGAPI
CCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCHHHHHHHHCCCCH
VALFAAGIAIRCVAPCLADKGAEPPVLAVAEDGSAVVPLLGGLAGANALAREIADALGVA
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDLLAGESTRVEGDARWLDDVALPRD
HEEECCCCEEEEEEEECCCCCCEEEECHHHHHHHHHHHCCCCCEECCCHHHHHHHCCCCC
AHAARVIRVTPHASRGDAHALLIHPRSVVVALGDGDGDIDGEGLRDDARSVSAPDATGRA
CCCEEEEEECCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCC
RANAAAPARAASPDLPPLAARIAAALAAHDLAPLALAAVVAPARRIAEHALTDAARALRA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLRFVETNARDAAGVLDAALPAALAPRVDASRAAAGSPRTTPPEPRDVAIAVARAPVDAD
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCEEEEEEECCCCCH
ALGIARGRLTVLGLGPGRADLMTPAARAALADATDIVGYATYVNMAGPLRADQQLHVSDN
HHEEECCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCC
REELQRARHAFELAARGRRVAVVSSGDPGVFAMAAAVLEALDGADDARWAAVELDVVPGV
HHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
SAALATAAEAGAPLGHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQ
HHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCC
FDRALDIVRRHRAPETVVVLGRDIGRPGATLATTTLAALSAQQVDMRTMVIVGSSTTRRV
HHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCHHHHH
ARDGARDWVYTPRWYR
HHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAAPAIVILGPGALETARRIQARFDGARVHALAGRAEADLAFAELGPHLRELYARGAPI
CCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCHHHHHHHHCCCCH
VALFAAGIAIRCVAPCLADKGAEPPVLAVAEDGSAVVPLLGGLAGANALAREIADALGVA
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAITTSGELRFGACMLNPPEGYALADLDAGKRFVSDLLAGESTRVEGDARWLDDVALPRD
HEEECCCCEEEEEEEECCCCCCEEEECHHHHHHHHHHHCCCCCEECCCHHHHHHHCCCCC
AHAARVIRVTPHASRGDAHALLIHPRSVVVALGDGDGDIDGEGLRDDARSVSAPDATGRA
CCCEEEEEECCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCC
RANAAAPARAASPDLPPLAARIAAALAAHDLAPLALAAVVAPARRIAEHALTDAARALRA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLRFVETNARDAAGVLDAALPAALAPRVDASRAAAGSPRTTPPEPRDVAIAVARAPVDAD
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCEEEEEEECCCCCH
ALGIARGRLTVLGLGPGRADLMTPAARAALADATDIVGYATYVNMAGPLRADQQLHVSDN
HHEEECCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCC
REELQRARHAFELAARGRRVAVVSSGDPGVFAMAAAVLEALDGADDARWAAVELDVVPGV
HHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
SAALATAAEAGAPLGHDFCLISLSDNLKPWAIIEKRIDHAAAADFALAFYNPVSRARPVQ
HHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCC
FDRALDIVRRHRAPETVVVLGRDIGRPGATLATTTLAALSAQQVDMRTMVIVGSSTTRRV
HHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCHHHHH
ARDGARDWVYTPRWYR
HHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]