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The map label for this gene is cobB [H]

Identifier: 237812225

GI number: 237812225

Start: 1925008

End: 1926606

Strand: Reverse

Name: cobB [H]

Synonym: GBP346_A1971

Alternate gene names: 237812225

Gene position: 1926606-1925008 (Counterclockwise)

Preceding gene: 237812226

Following gene: 237812219

Centisome position: 47.01

GC content: 74.48

Gene sequence:

>1599_bases
ATGCCCGCCTGCCCCGCGCTCTTCGTCGCCGCCGCCGCGTCCGGCCAGGGCAAGACGTCGGTGACGGCGGCGCTCGCGCG
CCATCACCGGCGGCTCGGCCGGCGCGTGCGCGTGTTCAAGACCGGCCCGGATTTTCTCGATCCGATGCTGCTCGCGCGCG
CGAGCGGCGCGCGCGTCTATTCGCTCGATCTCGGGATGGTCGGCGAGCGCGGCTGCCGCGCGCTGCTCGCGCGCGCCGCG
GCCGAGGCGGACGTGATCCTGATCGAAGGCGCGATGGGGCTCTTCGACGGCACGCCGTCGAGCGCCGATCTCGCGCAGGC
GTTCGGCGTGCCCGTCGCCGCGGTGATCGCCGCGCAATCGATGGCGCAGACGTTCGGCGCGCTCGCGTTCGGGCTCGCGC
ATTTCCGGCCCGGCTTGCCGTTTCACGGCGTGCTCGCGAACCGCGTCGGCTCCGAGCGCCATGCGCAACTGCTGCGCGGC
GCGCTGCCCGGGTCGATCCGCTGGCTCGGCCATCTGCCGCGCGATGCGCGGATCGCGCTGCCGGAGCGGCACCTCGGGCT
GCATCAGCCGGACGACGTCGCCGATCTCGACGCGCGGCTCGATCGCGCCGCCGATGCGATCGCGCACACGGCGCTCGCCG
CGCTGCCGCCCGTCGTCGAATTCGCGTGCGGCGACGCTGCAAATGCCGAGGCCGATGCCGGAGACGGCGGCGCGACGATC
CCGGCGCGGGACGCCTCGCGCACTGCTCATCGCACGGCCACGGCGGCGCGCGTGGCCGCCGGGCGCGGCGCCCTCGCGGG
TGCCACGATGCGGGCGGCGCACGGCGAGCGCGCCGCCCGCTCGGCGGATGCGGCAGCGCACGAAACAGTAGATGACGCGT
TACTTGACGCGGCAAAACGCGCCGGGACCGGCGACGGAGCGTTGTCGCCTTCGCCCGACGCGGGCGGCGCAATCGGCGCA
ATTCGCTCGACCGAGACGACCGAGGCCGTGCCGAGCCTCGTCGGCCGCCGGATCGCGATCGCGCGCGACGCGGCGTTCTC
GTTCATCTATCCGGCGAATCTCGATCAACTCGAAGCGCTCGGCGCCGAGCTCGCGTTCTTCTCGCCGCTTGCCGACGAGC
CGGTGCCCGACGGTTCGCACGCGCTCTATCTGCCGGGCGGCTATCCGGAGCTGCATGCGGCGCGGCTCGCGGCGAACGCG
ACGGCCGCGCGCTCGATCGCCGCGCACGTCGCGGCGGGCCGGCGCGTCGTCGCCGAATGCGGCGGCATGCTGTATCTGAG
CGATGCGCTGACGGACGCGGACGGCGTGACGACGCCGATGCTCGGCCTCGTGCCCGGCCACGCGACGATGCAGCGGCGTT
TCGCCGCGCTCGGCATGCAGACGCTCGCGACGCGCTTCGGCGCGATGACGGGCCACACGTTCCACTACTCGCGCCTCGCG
ACGCCGCTTGCGCCCGTCGCCGCCGCGACGCGGCCGGACGACGGCGCGGCGGGCGAACCGGTGTATCGGCACGGGCCGAT
CGTCGCGACGTATCTGCATGCGTACTGGCCGTCGAATCCGCGCGCGGCGGCCGCGCTTTTCGCGGGCGACGCGCCGTAA

Upstream 100 bases:

>100_bases
CTCGTCGACGCGGCCGATCTCGTCACCGAAATGCGGCTCGTCAAGCATCCGTACAAGGAGCAAGGCGTGAAGGCGCAGCG
CGGCGTGGAGTTCTGACGCG

Downstream 100 bases:

>100_bases
GCCGCGCGCCGCGCGGTCACCGAAGGCGCGCAGCGCCGCTTGCCGCGCGCTTTGGGCTCGTCGGGGGCGGCAAGCGACGC
AGCTTCGCGATCCATGTGTA

Product: cobyrinic Acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MPACPALFVAAAASGQGKTSVTAALARHHRRLGRRVRVFKTGPDFLDPMLLARASGARVYSLDLGMVGERGCRALLARAA
AEADVILIEGAMGLFDGTPSSADLAQAFGVPVAAVIAAQSMAQTFGALAFGLAHFRPGLPFHGVLANRVGSERHAQLLRG
ALPGSIRWLGHLPRDARIALPERHLGLHQPDDVADLDARLDRAADAIAHTALAALPPVVEFACGDAANAEADAGDGGATI
PARDASRTAHRTATAARVAAGRGALAGATMRAAHGERAARSADAAAHETVDDALLDAAKRAGTGDGALSPSPDAGGAIGA
IRSTETTEAVPSLVGRRIAIARDAAFSFIYPANLDQLEALGAELAFFSPLADEPVPDGSHALYLPGGYPELHAARLAANA
TAARSIAAHVAAGRRVVAECGGMLYLSDALTDADGVTTPMLGLVPGHATMQRRFAALGMQTLATRFGAMTGHTFHYSRLA
TPLAPVAAATRPDDGAAGEPVYRHGPIVATYLHAYWPSNPRAAAALFAGDAP

Sequences:

>Translated_532_residues
MPACPALFVAAAASGQGKTSVTAALARHHRRLGRRVRVFKTGPDFLDPMLLARASGARVYSLDLGMVGERGCRALLARAA
AEADVILIEGAMGLFDGTPSSADLAQAFGVPVAAVIAAQSMAQTFGALAFGLAHFRPGLPFHGVLANRVGSERHAQLLRG
ALPGSIRWLGHLPRDARIALPERHLGLHQPDDVADLDARLDRAADAIAHTALAALPPVVEFACGDAANAEADAGDGGATI
PARDASRTAHRTATAARVAAGRGALAGATMRAAHGERAARSADAAAHETVDDALLDAAKRAGTGDGALSPSPDAGGAIGA
IRSTETTEAVPSLVGRRIAIARDAAFSFIYPANLDQLEALGAELAFFSPLADEPVPDGSHALYLPGGYPELHAARLAANA
TAARSIAAHVAAGRRVVAECGGMLYLSDALTDADGVTTPMLGLVPGHATMQRRFAALGMQTLATRFGAMTGHTFHYSRLA
TPLAPVAAATRPDDGAAGEPVYRHGPIVATYLHAYWPSNPRAAAALFAGDAP
>Mature_531_residues
PACPALFVAAAASGQGKTSVTAALARHHRRLGRRVRVFKTGPDFLDPMLLARASGARVYSLDLGMVGERGCRALLARAAA
EADVILIEGAMGLFDGTPSSADLAQAFGVPVAAVIAAQSMAQTFGALAFGLAHFRPGLPFHGVLANRVGSERHAQLLRGA
LPGSIRWLGHLPRDARIALPERHLGLHQPDDVADLDARLDRAADAIAHTALAALPPVVEFACGDAANAEADAGDGGATIP
ARDASRTAHRTATAARVAAGRGALAGATMRAAHGERAARSADAAAHETVDDALLDAAKRAGTGDGALSPSPDAGGAIGAI
RSTETTEAVPSLVGRRIAIARDAAFSFIYPANLDQLEALGAELAFFSPLADEPVPDGSHALYLPGGYPELHAARLAANAT
AARSIAAHVAAGRRVVAECGGMLYLSDALTDADGVTTPMLGLVPGHATMQRRFAALGMQTLATRFGAMTGHTFHYSRLAT
PLAPVAAATRPDDGAAGEPVYRHGPIVATYLHAYWPSNPRAAAALFAGDAP

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 54522; Mature: 54391

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPACPALFVAAAASGQGKTSVTAALARHHRRLGRRVRVFKTGPDFLDPMLLARASGARVY
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCCEEE
SLDLGMVGERGCRALLARAAAEADVILIEGAMGLFDGTPSSADLAQAFGVPVAAVIAAQS
EECCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCHHHHHHHCCHHHHHHHHHH
MAQTFGALAFGLAHFRPGLPFHGVLANRVGSERHAQLLRGALPGSIRWLGHLPRDARIAL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCCCCEEEC
PERHLGLHQPDDVADLDARLDRAADAIAHTALAALPPVVEFACGDAANAEADAGDGGATI
CHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCCCC
PARDASRTAHRTATAARVAAGRGALAGATMRAAHGERAARSADAAAHETVDDALLDAAKR
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
AGTGDGALSPSPDAGGAIGAIRSTETTEAVPSLVGRRIAIARDAAFSFIYPANLDQLEAL
CCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHCCHHEEEHHCCEEEECCCCHHHHHHH
GAELAFFSPLADEPVPDGSHALYLPGGYPELHAARLAANATAARSIAAHVAAGRRVVAEC
HHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGMLYLSDALTDADGVTTPMLGLVPGHATMQRRFAALGMQTLATRFGAMTGHTFHYSRLA
CCEEEEECHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHH
TPLAPVAAATRPDDGAAGEPVYRHGPIVATYLHAYWPSNPRAAAALFAGDAP
CCHHHHHHCCCCCCCCCCCCCHHCCCCCEEHHHHHCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
PACPALFVAAAASGQGKTSVTAALARHHRRLGRRVRVFKTGPDFLDPMLLARASGARVY
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCCEEE
SLDLGMVGERGCRALLARAAAEADVILIEGAMGLFDGTPSSADLAQAFGVPVAAVIAAQS
EECCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCHHHHHHHCCHHHHHHHHHH
MAQTFGALAFGLAHFRPGLPFHGVLANRVGSERHAQLLRGALPGSIRWLGHLPRDARIAL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCCCCEEEC
PERHLGLHQPDDVADLDARLDRAADAIAHTALAALPPVVEFACGDAANAEADAGDGGATI
CHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCCCC
PARDASRTAHRTATAARVAAGRGALAGATMRAAHGERAARSADAAAHETVDDALLDAAKR
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
AGTGDGALSPSPDAGGAIGAIRSTETTEAVPSLVGRRIAIARDAAFSFIYPANLDQLEAL
CCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHCCHHEEEHHCCEEEECCCCHHHHHHH
GAELAFFSPLADEPVPDGSHALYLPGGYPELHAARLAANATAARSIAAHVAAGRRVVAEC
HHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGMLYLSDALTDADGVTTPMLGLVPGHATMQRRFAALGMQTLATRFGAMTGHTFHYSRLA
CCEEEEECHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHH
TPLAPVAAATRPDDGAAGEPVYRHGPIVATYLHAYWPSNPRAAAALFAGDAP
CCHHHHHHCCCCCCCCCCCCCHHCCCCCEEHHHHHCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]