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The map label for this gene is tcp [H]

Identifier: 237812150

GI number: 237812150

Start: 1835165

End: 1837045

Strand: Direct

Name: tcp [H]

Synonym: GBP346_A1896

Alternate gene names: 237812150

Gene position: 1835165-1837045 (Clockwise)

Preceding gene: 237812149

Following gene: 237812151

Centisome position: 44.78

GC content: 71.13

Gene sequence:

>1881_bases
ATGCTGCTGAAGAACATCACGATCAGAGCGCGCCTCGCCGTCACGATGGCGCTCCTTTCCGTCCTGCTGTGCGCCGTCGG
TGCGCTCGGCCTCTTCGGCATGAGCCGGGCCAACGACGCGAACGAGCAAACGTCGTCGAATCAACTGCCGAGCGCGATCG
ACGTGGCGAGCGCGGAGTTGTTCGCCGCCCGAGAGCGCCTCGTGCTCGATCGCGCGGCGCTCCTCGCGGGCACGCCGGAC
GTCGCGCCGACGATCGAGCGCGCGCGCCAGATGCGCGGAGTCTCCGATTCGTGGTGGAAAAAATACCTCGACCTGCCGCG
CGACGCGCAGGAGGACCGCCTCGTGCAGGACCTCGCGTCGAAACGGCAGATTCTGCAGCGTGAGCTCGACGCGGCCGCCG
CGTTGATCAACGCGAATGATCGCGACAGAATCCTCGAATCCGCCAAGCGGATGCAGAACGTATTCAACGATTTCTCGCTG
GCGAGCGAGGCGCTGCGCGCGTTTCAGCTCAAGCAGGCGAGCGTCAACTTCAGCGATGCGCAAAGCGTATACGCGGCGAG
CCGGGTCGCCAGCATCGCCGCGCTCGCGCTCGGCCTCGCGCTCTCGCTGTACTGCTTCCTGAGCCTGCGCGCGGCGATCG
CCCGGCCGCTCGCCGACGCGCTCGGTCATTTCGACGCGATCGCCGCGGGCGAGCTGCGCCGCCCGATCGTCGTCGAACGG
CGCGACGAGATGGGCCTGCTGCTCGAAGGGCTCGCGAAGATGCAGGCAAGCCTCGCGGGCACCGTGCGCGCGGTGCGCGT
CGGCAGCGAATCGATCGCGACGGCGGCCCGGCAGATCGCGGCGGGCAACATCGATCTGTCCTCGCGCACCGAGGAGCAGG
CGGCGGCGCTCGAACAGACGGCGTCGAGCATGGAGGAACTGACGGGCACGGTGCGGCGCAACGCGGATAACGCGCGGCAG
GCGAGCGCGCTCGCGGCGAGCGCGTCGGAGATCGCGAACAAGGGCAACGCGGTGGTCGGCCAGGTGGTCGGCACGATGGG
CGACATCAACCAGAGCTCCGCGAAGATCGCCGACATCATCACGATCATCGAGGGAATCGCGTTCCAGACCAACATCCTCG
CGCTGAACGCGGCGGTCGAGGCGGCGCGCGCGGGCGAGGAAGGGCGCGGCTTCGCGGTCGTCGCGGGCGAGGTGCGCAGC
CTCGCGCAGCGTTCGTCGACGGCCGCCAAGGAGATCAAGGAGCTGATCGACACGTCGGTCGAGCGCGTGCGCACGGGCTC
CATGCTCGTCGACGACGCGGGACGCACGATGAGCGAGGTGATCGGCGCGGTGCGGCGCGTGACCGACATCATGGGCGAGA
TCGCGGCGGCCTCGGACGAGCAGAGCACCGGCATCGACCAGGTGTCGCGCGCCGTATCGCAGATGGACGAGGTCACGCAG
CAGAACGCGGCGCTCGTTGAGCAGGCCGCGGCGGCCGCGCAATCGCTCGACGAGCAGGCCGCGCGGCTGCGCGCGACCGT
TTCGGTGTTCCATGTCGATGACGGCGATGCGCGCGATGTCGCCTCGCGCCCGCCGGCCCGGCCGGGGGCCGGCGCCGTGC
ACCGGGCGGCGGGCGCGGCCGCGCCGGCGCAGGCCGGCGCGTCTTCGGGCGCGCACGCCGCGCCGGCGGCGCATGCGGCG
CGCAAGCCCGCGCCGTCCACTGCGCTCGCGAAAGCCGCGCCTGTTGCGTCCGTTGCATCCGCTGCATCCGTTACGCCCGC
TGCGTCTGCGCCGACGCTTGCCGCGGCAGCGGCGAAGCCCAAACCCGCGCCCGCCGCGCCGCGCGCCGGGTCGGTTACTG
CGGCGTCCGCCGCGAGCGACGACGATTGGGAGACCTTCTAA

Upstream 100 bases:

>100_bases
GTCGAGCGCCGTAAACCAAGCGTGGCGAAGCAAACGTTTCGCCGCTGCGGGCCGGTCGAGCCGCCTCCGTCGCCTTGCGA
CGCCTCACAGGAAAAGAACC

Downstream 100 bases:

>100_bases
GATGAATGGGAAAACGTATCGGACAACGATCTACCCCCAATTTGATTGAACGATGACGCCCGCGCCAGCGGGCGTTTTTG
CATCGGGACCAGTCGCTTGC

Product: methyl-accepting chemotaxis protein I

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MLLKNITIRARLAVTMALLSVLLCAVGALGLFGMSRANDANEQTSSNQLPSAIDVASAELFAARERLVLDRAALLAGTPD
VAPTIERARQMRGVSDSWWKKYLDLPRDAQEDRLVQDLASKRQILQRELDAAAALINANDRDRILESAKRMQNVFNDFSL
ASEALRAFQLKQASVNFSDAQSVYAASRVASIAALALGLALSLYCFLSLRAAIARPLADALGHFDAIAAGELRRPIVVER
RDEMGLLLEGLAKMQASLAGTVRAVRVGSESIATAARQIAAGNIDLSSRTEEQAAALEQTASSMEELTGTVRRNADNARQ
ASALAASASEIANKGNAVVGQVVGTMGDINQSSAKIADIITIIEGIAFQTNILALNAAVEAARAGEEGRGFAVVAGEVRS
LAQRSSTAAKEIKELIDTSVERVRTGSMLVDDAGRTMSEVIGAVRRVTDIMGEIAAASDEQSTGIDQVSRAVSQMDEVTQ
QNAALVEQAAAAAQSLDEQAARLRATVSVFHVDDGDARDVASRPPARPGAGAVHRAAGAAAPAQAGASSGAHAAPAAHAA
RKPAPSTALAKAAPVASVASAASVTPAASAPTLAAAAAKPKPAPAAPRAGSVTAASAASDDDWETF

Sequences:

>Translated_626_residues
MLLKNITIRARLAVTMALLSVLLCAVGALGLFGMSRANDANEQTSSNQLPSAIDVASAELFAARERLVLDRAALLAGTPD
VAPTIERARQMRGVSDSWWKKYLDLPRDAQEDRLVQDLASKRQILQRELDAAAALINANDRDRILESAKRMQNVFNDFSL
ASEALRAFQLKQASVNFSDAQSVYAASRVASIAALALGLALSLYCFLSLRAAIARPLADALGHFDAIAAGELRRPIVVER
RDEMGLLLEGLAKMQASLAGTVRAVRVGSESIATAARQIAAGNIDLSSRTEEQAAALEQTASSMEELTGTVRRNADNARQ
ASALAASASEIANKGNAVVGQVVGTMGDINQSSAKIADIITIIEGIAFQTNILALNAAVEAARAGEEGRGFAVVAGEVRS
LAQRSSTAAKEIKELIDTSVERVRTGSMLVDDAGRTMSEVIGAVRRVTDIMGEIAAASDEQSTGIDQVSRAVSQMDEVTQ
QNAALVEQAAAAAQSLDEQAARLRATVSVFHVDDGDARDVASRPPARPGAGAVHRAAGAAAPAQAGASSGAHAAPAAHAA
RKPAPSTALAKAAPVASVASAASVTPAASAPTLAAAAAKPKPAPAAPRAGSVTAASAASDDDWETF
>Mature_626_residues
MLLKNITIRARLAVTMALLSVLLCAVGALGLFGMSRANDANEQTSSNQLPSAIDVASAELFAARERLVLDRAALLAGTPD
VAPTIERARQMRGVSDSWWKKYLDLPRDAQEDRLVQDLASKRQILQRELDAAAALINANDRDRILESAKRMQNVFNDFSL
ASEALRAFQLKQASVNFSDAQSVYAASRVASIAALALGLALSLYCFLSLRAAIARPLADALGHFDAIAAGELRRPIVVER
RDEMGLLLEGLAKMQASLAGTVRAVRVGSESIATAARQIAAGNIDLSSRTEEQAAALEQTASSMEELTGTVRRNADNARQ
ASALAASASEIANKGNAVVGQVVGTMGDINQSSAKIADIITIIEGIAFQTNILALNAAVEAARAGEEGRGFAVVAGEVRS
LAQRSSTAAKEIKELIDTSVERVRTGSMLVDDAGRTMSEVIGAVRRVTDIMGEIAAASDEQSTGIDQVSRAVSQMDEVTQ
QNAALVEQAAAAAQSLDEQAARLRATVSVFHVDDGDARDVASRPPARPGAGAVHRAAGAAAPAQAGASSGAHAAPAAHAA
RKPAPSTALAKAAPVASVASAASVTPAASAPTLAAAAAKPKPAPAAPRAGSVTAASAASDDDWETF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=331, Percent_Identity=59.5166163141994, Blast_Score=342, Evalue=5e-95,
Organism=Escherichia coli, GI2367378, Length=526, Percent_Identity=45.8174904942966, Blast_Score=338, Evalue=9e-94,
Organism=Escherichia coli, GI1788194, Length=523, Percent_Identity=42.6386233269598, Blast_Score=337, Evalue=2e-93,
Organism=Escherichia coli, GI1787690, Length=322, Percent_Identity=58.0745341614907, Blast_Score=320, Evalue=2e-88,
Organism=Escherichia coli, GI1789453, Length=328, Percent_Identity=37.1951219512195, Blast_Score=213, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 64740; Mature: 64740

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKNITIRARLAVTMALLSVLLCAVGALGLFGMSRANDANEQTSSNQLPSAIDVASAEL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
FAARERLVLDRAALLAGTPDVAPTIERARQMRGVSDSWWKKYLDLPRDAQEDRLVQDLAS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
KRQILQRELDAAAALINANDRDRILESAKRMQNVFNDFSLASEALRAFQLKQASVNFSDA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
QSVYAASRVASIAALALGLALSLYCFLSLRAAIARPLADALGHFDAIAAGELRRPIVVER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
RDEMGLLLEGLAKMQASLAGTVRAVRVGSESIATAARQIAAGNIDLSSRTEEQAAALEQT
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
ASSMEELTGTVRRNADNARQASALAASASEIANKGNAVVGQVVGTMGDINQSSAKIADII
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHH
TIIEGIAFQTNILALNAAVEAARAGEEGRGFAVVAGEVRSLAQRSSTAAKEIKELIDTSV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
ERVRTGSMLVDDAGRTMSEVIGAVRRVTDIMGEIAAASDEQSTGIDQVSRAVSQMDEVTQ
HHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
QNAALVEQAAAAAQSLDEQAARLRATVSVFHVDDGDARDVASRPPARPGAGAVHRAAGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHCCCCCCCCCCCHHHHHHCCC
APAQAGASSGAHAAPAAHAARKPAPSTALAKAAPVASVASAASVTPAASAPTLAAAAAKP
CCHHCCCCCCCCCCHHHHHHCCCCCCHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHCCCC
KPAPAAPRAGSVTAASAASDDDWETF
CCCCCCCCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MLLKNITIRARLAVTMALLSVLLCAVGALGLFGMSRANDANEQTSSNQLPSAIDVASAEL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
FAARERLVLDRAALLAGTPDVAPTIERARQMRGVSDSWWKKYLDLPRDAQEDRLVQDLAS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
KRQILQRELDAAAALINANDRDRILESAKRMQNVFNDFSLASEALRAFQLKQASVNFSDA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
QSVYAASRVASIAALALGLALSLYCFLSLRAAIARPLADALGHFDAIAAGELRRPIVVER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
RDEMGLLLEGLAKMQASLAGTVRAVRVGSESIATAARQIAAGNIDLSSRTEEQAAALEQT
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
ASSMEELTGTVRRNADNARQASALAASASEIANKGNAVVGQVVGTMGDINQSSAKIADII
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHH
TIIEGIAFQTNILALNAAVEAARAGEEGRGFAVVAGEVRSLAQRSSTAAKEIKELIDTSV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
ERVRTGSMLVDDAGRTMSEVIGAVRRVTDIMGEIAAASDEQSTGIDQVSRAVSQMDEVTQ
HHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
QNAALVEQAAAAAQSLDEQAARLRATVSVFHVDDGDARDVASRPPARPGAGAVHRAAGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHCCCCCCCCCCCHHHHHHCCC
APAQAGASSGAHAAPAAHAARKPAPSTALAKAAPVASVASAASVTPAASAPTLAAAAAKP
CCHHCCCCCCCCCCHHHHHHCCCCCCHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHCCCC
KPAPAAPRAGSVTAASAASDDDWETF
CCCCCCCCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]