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The map label for this gene is rbsK_1 [H]

Identifier: 237812149

GI number: 237812149

Start: 1833976

End: 1834950

Strand: Direct

Name: rbsK_1 [H]

Synonym: GBP346_A1895

Alternate gene names: 237812149

Gene position: 1833976-1834950 (Clockwise)

Preceding gene: 237812148

Following gene: 237812150

Centisome position: 44.75

GC content: 77.54

Gene sequence:

>975_bases
ATGACGGCCGCCGTCGAACGCGCGGCCGGCGGGGCCTCGCCCGCGCGCGCCGGCAGGGTGATGGTGGTCGGCAGCCTGAA
CATGGACCTCGTCGTGCGCTCGGCGCGGCTGCCGCGGCCGGGCGAGACGCTCGCCGGCCGCTCGTTCGCGCAGGCGGCGG
GCGGCAAGGGCGGCAACCAGGCGGTCGCGGCCGCGCGGCTCGGCGCGCAGGTGGCGATGCTCGGCCGCGTCGGCGCGGAC
GCGCACGGCGCCGCGCTGCGCGCGGGGCTCGTCGCCGAGGGGATCGATTGCGTCGCGCTGTCGGTCAGCGCGACGGCGAC
GACGGGCGTCGCGCTCATCGTCGTCGACGATGCGAGCCAGAACGCGATCGTGATCGTCGCGGGCAGCAACGGCGAGGTGA
CCCCCGAATCGATCGCCGGGCACGAGGCGGCGATCGCCGCGGCCGACGTGCTGATCTGCCAGCTCGAGACGCCCGCCGCC
GCGGTTCGCGCGGCGCTGGCCGCCGGCCGCCGGCTCGGCAAGACCGTCGTGCTGAATCCGGCGCCCGCTGCCGGCCCGCT
GCCCGCCGACTGGTTGCCGCTCGTCGATTACCTGATCCCGAACGAAATCGAGGCCGCCGCGCTGACCGGCTTGCCGGTGC
GCGACCCGGTGAGCGCCGAGACCGCCGCGCGCGCGCTTGCGGCGGCTGGCGCGCGCAACGTGATCGTCACGCTGGGCGGC
CAGGGCGTTCTCGCGCTGACGGCGGACGGCGACGCGCGCCACTACCCGGCGCCGCGCGTCGCGCCCGTCGACACGACGGC
CGCGGGGGACACGTTCATCGGAGGTTTCGCCGCGCGGCTCGCCGCGCGCGACGCGCCGCACGACGCGATCCGGTTCGCGC
AGCGCGCGGCTGCGTTGTCGGTCACGCGCGCGGGCGCGCAGCCGTCGATTCCGACGCTCGCCGAGCTCGACGCGTTCGCG
CCGGGGCCGGCGTGA

Upstream 100 bases:

>100_bases
CGTCGGGCGCGCCGCAGCGCCGCCGCGTCGTGTCGCCGCGCCTCGTGCTGCGCGAATCGACGACTGTCTACGTGGAGCCG
GCCGACGCCGGGTATCGCGG

Downstream 100 bases:

>100_bases
CACAACGCCGCGGTCGCGCCGGGCATGTAAGCCAAGAGAAAGAAAATATCGAGCCGGCGGCCGCGCCAAATAAGTTTTTC
TTCGCACGGGCGGCTGCCCA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQAVAAARLGAQVAMLGRVGAD
AHGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQNAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAA
AVRAALAAGRRLGKTVVLNPAPAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPVSAETAARALAAAGARNVIVTLGG
QGVLALTADGDARHYPAPRVAPVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALSVTRAGAQPSIPTLAELDAFA
PGPA

Sequences:

>Translated_324_residues
MTAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQAVAAARLGAQVAMLGRVGAD
AHGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQNAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAA
AVRAALAAGRRLGKTVVLNPAPAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPVSAETAARALAAAGARNVIVTLGG
QGVLALTADGDARHYPAPRVAPVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALSVTRAGAQPSIPTLAELDAFA
PGPA
>Mature_323_residues
TAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQAVAAARLGAQVAMLGRVGADA
HGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQNAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAAA
VRAALAAGRRLGKTVVLNPAPAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPVSAETAARALAAAGARNVIVTLGGQ
GVLALTADGDARHYPAPRVAPVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALSVTRAGAQPSIPTLAELDAFAP
GPA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=297, Percent_Identity=40.0673400673401, Blast_Score=184, Evalue=8e-47,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=43.75, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI87082343, Length=304, Percent_Identity=31.9078947368421, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788484, Length=315, Percent_Identity=27.3015873015873, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=305, Percent_Identity=40.655737704918, Blast_Score=198, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6319884, Length=335, Percent_Identity=31.3432835820896, Blast_Score=139, Evalue=9e-34,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=40.1993355481728, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24583886, Length=299, Percent_Identity=33.1103678929766, Blast_Score=138, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31878; Mature: 31746

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQ
CCCCHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCHHCCCHHHHHHCCCCCCH
AVAAARLGAQVAMLGRVGADAHGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQ
HHHHHHHCHHEEEHHHCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCC
NAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAAAVRAALAAGRRLGKTVVLNP
CEEEEEECCCCCCCHHHHCCCHHHHHEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEECC
APAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPVSAETAARALAAAGARNVIVTLGG
CCCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECC
QGVLALTADGDARHYPAPRVAPVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALS
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VTRAGAQPSIPTLAELDAFAPGPA
HEECCCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
TAAVERAAGGASPARAGRVMVVGSLNMDLVVRSARLPRPGETLAGRSFAQAAGGKGGNQ
CCCHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCHHCCCHHHHHHCCCCCCH
AVAAARLGAQVAMLGRVGADAHGAALRAGLVAEGIDCVALSVSATATTGVALIVVDDASQ
HHHHHHHCHHEEEHHHCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCC
NAIVIVAGSNGEVTPESIAGHEAAIAAADVLICQLETPAAAVRAALAAGRRLGKTVVLNP
CEEEEEECCCCCCCHHHHCCCHHHHHEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEECC
APAAGPLPADWLPLVDYLIPNEIEAAALTGLPVRDPVSAETAARALAAAGARNVIVTLGG
CCCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECC
QGVLALTADGDARHYPAPRVAPVDTTAAGDTFIGGFAARLAARDAPHDAIRFAQRAAALS
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VTRAGAQPSIPTLAELDAFAPGPA
HEECCCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]