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The map label for this gene is alsB [H]

Identifier: 237812144

GI number: 237812144

Start: 1829158

End: 1830120

Strand: Direct

Name: alsB [H]

Synonym: GBP346_A1890

Alternate gene names: 237812144

Gene position: 1829158-1830120 (Clockwise)

Preceding gene: 237812143

Following gene: 237812146

Centisome position: 44.63

GC content: 66.67

Gene sequence:

>963_bases
ATGGATGTCAGCCTCCGCCGCCGCGTGCTAGCCGTCGCGGCCGTTTGCGTCGCCGTCGCCGCGGCCGGGCCGTTCTCGGT
CGCGCGCGCCGAGACCGCGCACAAGCCGAAGGTCGCCCTCGTGATGAAATCGCTCGCCAACGAGTTCTTCCTCACGATGG
AGAACGGCGCGAAGGAATACCAGAAACACAACGCGAGCCAGTTCGATCTCGTCACGAACGGCATCAAGGACGAAACGGAC
ACCGCGAGCCAGATCCGTATCGTCGAGCAGATGATCGTGTCGAAGGTCGACGCGATCGTGCTCGCGCCCGCCGATTCGAA
GGCGCTCGTGCCCGTCGTCAAGAAGGCCGTCGACGCGGGGATCATCGTCGTGAACATCGACAACCGGCTCGATCCGGACG
TGCTCAAGTCGAAGGGCCTGAACGTGCCGTTCGTCGGCCCGGACAACCGCAAGGGCGCGCGGATGGTCGGCGACTATCTC
GCGAAGCGGCTGAAGGCGGGCGATGCGGTGGGCATCGTCGAGGGCGTGCCGACGACCACCAACGCGCAGCAGCGCACCGC
GGGCTTCCAGGACGCGATGAAGGCGGCGGGCGCGAAGGTCGTGTCGATCCAGTCGGGCGAATGGGAGATCGACAAGGGCA
ACGCGGTCGCCGCCGCGATGCTCAACGAATACCCGAACCTGAAGGCGCTCCTTTGCGGCAACGACAACATGGCGATCGGC
GCCGTGTCCGCGGTGCGCGCGGCGGGCCGCCAGGGCAAGGTGTATGTCGTCGGCTACGACAACATCAACGCGATCAAGCC
GATGCTCAAGGACGGCCGCGTGCTCGCGACCGCCGACCAGTACGCGGCGAAGCAGGCGGTGTTCGGCATCGACACGGCGC
TCAAGGCGCTCGCCGAGCATCGCAAGCAGGCCGACATGACGGGCGTCGTCGCGACGCCCGTCGATCTCGTGACGAAGCCG
TAA

Upstream 100 bases:

>100_bases
GTTTGAAACGCGTTGTCGGCTTGGTCTGCGCAAACGTTTGCTCGTCGCAAAAGCGACACTCGATCCGTTCGGGACCCGCA
ACCACTGCCAGGAGAGTCGC

Downstream 100 bases:

>100_bases
CCCGGCGCGGCGGCGGCGCAGCGCGCCGCTCAAGAACGCCGCGAGGCGGCCGATATCAGGCTAGAGCGTGACCCAGGCCG
CCTCGCGTCCTCGTCCGCGC

Product: binding protein component of ABC ribose transporter

Products: ADP; phosphate; ribose [Cytoplasm]; D-allose [Cytoplasm] [C]

Alternate protein names: ALBP [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MDVSLRRRVLAVAAVCVAVAAAGPFSVARAETAHKPKVALVMKSLANEFFLTMENGAKEYQKHNASQFDLVTNGIKDETD
TASQIRIVEQMIVSKVDAIVLAPADSKALVPVVKKAVDAGIIVVNIDNRLDPDVLKSKGLNVPFVGPDNRKGARMVGDYL
AKRLKAGDAVGIVEGVPTTTNAQQRTAGFQDAMKAAGAKVVSIQSGEWEIDKGNAVAAAMLNEYPNLKALLCGNDNMAIG
AVSAVRAAGRQGKVYVVGYDNINAIKPMLKDGRVLATADQYAAKQAVFGIDTALKALAEHRKQADMTGVVATPVDLVTKP

Sequences:

>Translated_320_residues
MDVSLRRRVLAVAAVCVAVAAAGPFSVARAETAHKPKVALVMKSLANEFFLTMENGAKEYQKHNASQFDLVTNGIKDETD
TASQIRIVEQMIVSKVDAIVLAPADSKALVPVVKKAVDAGIIVVNIDNRLDPDVLKSKGLNVPFVGPDNRKGARMVGDYL
AKRLKAGDAVGIVEGVPTTTNAQQRTAGFQDAMKAAGAKVVSIQSGEWEIDKGNAVAAAMLNEYPNLKALLCGNDNMAIG
AVSAVRAAGRQGKVYVVGYDNINAIKPMLKDGRVLATADQYAAKQAVFGIDTALKALAEHRKQADMTGVVATPVDLVTKP
>Mature_320_residues
MDVSLRRRVLAVAAVCVAVAAAGPFSVARAETAHKPKVALVMKSLANEFFLTMENGAKEYQKHNASQFDLVTNGIKDETD
TASQIRIVEQMIVSKVDAIVLAPADSKALVPVVKKAVDAGIIVVNIDNRLDPDVLKSKGLNVPFVGPDNRKGARMVGDYL
AKRLKAGDAVGIVEGVPTTTNAQQRTAGFQDAMKAAGAKVVSIQSGEWEIDKGNAVAAAMLNEYPNLKALLCGNDNMAIG
AVSAVRAAGRQGKVYVVGYDNINAIKPMLKDGRVLATADQYAAKQAVFGIDTALKALAEHRKQADMTGVVATPVDLVTKP

Specific function: Part of the binding-protein-dependent transport system AlsBAC for D-allose [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790526, Length=260, Percent_Identity=35, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790192, Length=306, Percent_Identity=31.0457516339869, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1790674, Length=205, Percent_Identity=32.1951219512195, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788898, Length=290, Percent_Identity=26.551724137931, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001761 [H]

Pfam domain/function: PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 33776; Mature: 33776

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVSLRRRVLAVAAVCVAVAAAGPFSVARAETAHKPKVALVMKSLANEFFLTMENGAKEY
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCHHHH
QKHNASQFDLVTNGIKDETDTASQIRIVEQMIVSKVDAIVLAPADSKALVPVVKKAVDAG
HHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHCCC
IIVVNIDNRLDPDVLKSKGLNVPFVGPDNRKGARMVGDYLAKRLKAGDAVGIVEGVPTTT
EEEEEECCCCCHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCC
NAQQRTAGFQDAMKAAGAKVVSIQSGEWEIDKGNAVAAAMLNEYPNLKALLCGNDNMAIG
CHHHHHCCHHHHHHHCCCEEEEEECCCEEECCCCCHHHHHHHCCCCCEEEEECCCCCEEH
AVSAVRAAGRQGKVYVVGYDNINAIKPMLKDGRVLATADQYAAKQAVFGIDTALKALAEH
HHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
RKQADMTGVVATPVDLVTKP
HHHCCCCCEEECCHHHHCCC
>Mature Secondary Structure
MDVSLRRRVLAVAAVCVAVAAAGPFSVARAETAHKPKVALVMKSLANEFFLTMENGAKEY
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCHHHH
QKHNASQFDLVTNGIKDETDTASQIRIVEQMIVSKVDAIVLAPADSKALVPVVKKAVDAG
HHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHCCC
IIVVNIDNRLDPDVLKSKGLNVPFVGPDNRKGARMVGDYLAKRLKAGDAVGIVEGVPTTT
EEEEEECCCCCHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCC
NAQQRTAGFQDAMKAAGAKVVSIQSGEWEIDKGNAVAAAMLNEYPNLKALLCGNDNMAIG
CHHHHHCCHHHHHHHCCCEEEEEECCCEEECCCCCHHHHHHHCCCCCEEEEECCCCCEEH
AVSAVRAAGRQGKVYVVGYDNINAIKPMLKDGRVLATADQYAAKQAVFGIDTALKALAEH
HHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
RKQADMTGVVATPVDLVTKP
HHHCCCCCEEECCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; ribose [Periplasm]; D-allose [Periplasm]; ATP [C]

Specific reaction: ATP + H2O + ribose [Periplasm] = ADP + phosphate + ribose [Cytoplasm] D-allose [Periplasm] + ATP + H2O = D-allose [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 8576032; 9401019; 10064713 [H]