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The map label for this gene is ychM [C]

Identifier: 237812088

GI number: 237812088

Start: 1779443

End: 1781155

Strand: Direct

Name: ychM [C]

Synonym: GBP346_A1830

Alternate gene names: 237812088

Gene position: 1779443-1781155 (Clockwise)

Preceding gene: 237812087

Following gene: 237812092

Centisome position: 43.42

GC content: 70.87

Gene sequence:

>1713_bases
ATGGATCTCCGCTCGAAGCACATCGACGCGCCGCCGCAGCATGCCGCGCATTTCGCGCCGCTCGACGAGCCGCCCGCGCC
GCGCGCCCGCCGCACCGCGCTCGACGCGCTCGCCGGGCTGTCGATCGCGGGCCTTCTGATACCCGAGGCGGTCGCCTACG
CCGGGCTCGCGAACCTGCCGCCGCAGGCGGGGCTCATCGCGCTCGTCGTGGGGCTCGTCGTCTACGCGATCGCGGGCAGC
AGCCGTTTCGCGATCGTGTCGGCGACGTCGTCGTCGGCCGTCGTGCTCGCGGCGACCGTGATGTCCGAGGCCGGACCGGG
CGCCGCCGCGCAGTTGATGCTCGCCGCGGCGCTCGTCGCGACGACGGGCATCCTGTTCATCCTCGCGGGCGCCGCGCGTC
TCGGCGGCATGTCGGATTTCATCGCGCGGCCGGTGCTGCGCGGCTTCACGTTCGGCCTTGCACTCACGATCGTGATCAAG
CAGTTGCCGAAGATGCTCGACGTGCCGATCCATCACGGCGATACGCTGCGCGTCGCGCTCGACCTGCTGCTCGGCATTGC
GGGCTGCAATGTCCGCAGCGCGGCGCTCGGCGCGGCCGCGCTGGCGATCCTGTTCGCGCTCGGCAGGCGCACGCGCGTGC
CGGCGACGCTCGTCGTGATCGTGCTCGGCATCGCGGCCGGCTACTGGATCGACTGGCATCGCTACGGCATCGCCGTCGTC
GGTACGATCGATCTGCAGAATCTCGCGTTCGGCATGCCGGTGCTCGGCCGCTCCGGCTGGATGCAGACGGCCGAGTTCGG
CTTCGCGCTGATGCTGATCCTGTACGCGGAATCGTACGGGTCGATTCGCAACTTCGCGCTCAAGCACGGCGACACGGTCT
CGCCGAACCGCGATCTCGTCGCGCTCGGCTGCGCGAACCTCGTATCGGGGCTGCTGCATGGGATGCCCGTCGGCGCGGGC
TATTCGGCGACCTCGGCGAACGAGGCGGCGGGCGCGCAAACGCGTATGGCGGGCCTGTTCGCGGCCGCCGTGATCGCGCT
GATCGCCTGGCTGCTGCTGCCGCAGCTCGCGCGCATTCCCGAGCCCGTGCTCGCGGCGATCGTGATCTTCGCGGTCAGCC
ATTCGCTGCATCCGGAGGTGTTCCGGCCGTACTGGACCTGGCATCGGGACCGGATCGTCGTGATCGCCGCGCTCGCGGCG
GTGATCGTGCTCGGCGTGCTGCACGGCCTGCTCGCCGCGATCGGCGTGAGCCTGCTGCTCACGTTGCGGCAATTGTCCGA
GCCGAACGTGAGCGTGCTGGGCCGGCTGCGCGGGAGCCACGATTTCGTCGACGTGTCGATGCACGAGGATGCGAAGCCGA
TCCCCGGCGTGCTGATCGTGCGGCCGGAAGCCCAGCTCTTCTTCGCGAACGCGGAGCGCGTGCTGACCATGGCGAGGCGC
CTCGCGCGCGACGCGCAGCCGCCCGTGCACACGGTGATGCTGAGTCTCGAGGAATCGCCCGACGTCGACGGCACGACGAT
CGAGGCGCTGAAGACGTTCGGCGCCGAATGCGATGCGCGCGGCTGGCGCCTCGCGCTCGTGCGCCTGAAGCCGAACGTGC
TGCGCGTGCTGCAACGCGCGGCGGACGGCGGGCTGCGCGCGGATGCGCTGTCGGAGCTGAGCGTCGACGAGAGCCTGCAA
TCGCTGACGGCGGGCGAGTTGCCGCGCGCGTGA

Upstream 100 bases:

>100_bases
CAGGAGGCGCGCTATCTGCCGGGCTGGTCCGGCGTGATCGCGGCGCCGCGCTGAGCGCCACACCTTCGTTCGCACGACGG
GCAACACCCACGGAACGCGC

Downstream 100 bases:

>100_bases
CGGACGCGGATGCGGGCGCGATGCGTCGATGCGTCGATGCGTGACGCTCGATGTCCGATGTCCGATGTCCGATGTCCGAT
GTCCGATGTCCGATGTCCGA

Product: sulfate permease family protein

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MDLRSKHIDAPPQHAAHFAPLDEPPAPRARRTALDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALVVGLVVYAIAGS
SRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVATTGILFILAGAARLGGMSDFIARPVLRGFTFGLALTIVIK
QLPKMLDVPIHHGDTLRVALDLLLGIAGCNVRSAALGAAALAILFALGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
GTIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTVSPNRDLVALGCANLVSGLLHGMPVGAG
YSATSANEAAGAQTRMAGLFAAAVIALIAWLLLPQLARIPEPVLAAIVIFAVSHSLHPEVFRPYWTWHRDRIVVIAALAA
VIVLGVLHGLLAAIGVSLLLTLRQLSEPNVSVLGRLRGSHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLALVRLKPNVLRVLQRAADGGLRADALSELSVDESLQ
SLTAGELPRA

Sequences:

>Translated_570_residues
MDLRSKHIDAPPQHAAHFAPLDEPPAPRARRTALDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALVVGLVVYAIAGS
SRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVATTGILFILAGAARLGGMSDFIARPVLRGFTFGLALTIVIK
QLPKMLDVPIHHGDTLRVALDLLLGIAGCNVRSAALGAAALAILFALGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
GTIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTVSPNRDLVALGCANLVSGLLHGMPVGAG
YSATSANEAAGAQTRMAGLFAAAVIALIAWLLLPQLARIPEPVLAAIVIFAVSHSLHPEVFRPYWTWHRDRIVVIAALAA
VIVLGVLHGLLAAIGVSLLLTLRQLSEPNVSVLGRLRGSHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLALVRLKPNVLRVLQRAADGGLRADALSELSVDESLQ
SLTAGELPRA
>Mature_570_residues
MDLRSKHIDAPPQHAAHFAPLDEPPAPRARRTALDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALVVGLVVYAIAGS
SRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVATTGILFILAGAARLGGMSDFIARPVLRGFTFGLALTIVIK
QLPKMLDVPIHHGDTLRVALDLLLGIAGCNVRSAALGAAALAILFALGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
GTIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTVSPNRDLVALGCANLVSGLLHGMPVGAG
YSATSANEAAGAQTRMAGLFAAAVIALIAWLLLPQLARIPEPVLAAIVIFAVSHSLHPEVFRPYWTWHRDRIVVIAALAA
VIVLGVLHGLLAAIGVSLLLTLRQLSEPNVSVLGRLRGSHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLALVRLKPNVLRVLQRAADGGLRADALSELSVDESLQ
SLTAGELPRA

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI39752683, Length=491, Percent_Identity=24.847250509165, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI45827800, Length=491, Percent_Identity=24.847250509165, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI94721255, Length=460, Percent_Identity=28.0434782608696, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI94721253, Length=460, Percent_Identity=28.0434782608696, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI94721259, Length=460, Percent_Identity=28.0434782608696, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI94721257, Length=460, Percent_Identity=28.0434782608696, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI47131207, Length=492, Percent_Identity=27.6422764227642, Blast_Score=126, Evalue=6e-29,
Organism=Homo sapiens, GI20336272, Length=492, Percent_Identity=27.6422764227642, Blast_Score=126, Evalue=6e-29,
Organism=Homo sapiens, GI269784651, Length=488, Percent_Identity=24.3852459016393, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI217272867, Length=482, Percent_Identity=23.8589211618257, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI16418413, Length=482, Percent_Identity=23.8589211618257, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI4557535, Length=487, Percent_Identity=23.6139630390144, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI45827802, Length=448, Percent_Identity=24.1071428571429, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4505697, Length=490, Percent_Identity=24.4897959183673, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI100913030, Length=490, Percent_Identity=22.8571428571429, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI262206105, Length=270, Percent_Identity=25.5555555555556, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI262206075, Length=270, Percent_Identity=25.5555555555556, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI262206069, Length=270, Percent_Identity=25.5555555555556, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI262206063, Length=270, Percent_Identity=25.5555555555556, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI20336282, Length=508, Percent_Identity=22.244094488189, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI16306483, Length=508, Percent_Identity=22.244094488189, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI16418457, Length=548, Percent_Identity=21.7153284671533, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI301601599, Length=548, Percent_Identity=21.7153284671533, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87081859, Length=205, Percent_Identity=33.1707317073171, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17551690, Length=533, Percent_Identity=25.703564727955, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17566848, Length=572, Percent_Identity=25.3496503496504, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI86565215, Length=495, Percent_Identity=24.040404040404, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI193203292, Length=483, Percent_Identity=22.7743271221532, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI86564196, Length=474, Percent_Identity=21.7299578059072, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562578, Length=534, Percent_Identity=22.4719101123595, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI86564876, Length=521, Percent_Identity=20.5374280230326, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI86565213, Length=263, Percent_Identity=25.4752851711027, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6325260, Length=497, Percent_Identity=24.9496981891348, Blast_Score=134, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24651449, Length=561, Percent_Identity=24.777183600713, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24649801, Length=564, Percent_Identity=24.822695035461, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI21358229, Length=573, Percent_Identity=24.956369982548, Blast_Score=109, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24666186, Length=519, Percent_Identity=23.8921001926782, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI19922482, Length=594, Percent_Identity=22.7272727272727, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24663084, Length=546, Percent_Identity=23.992673992674, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21357695, Length=546, Percent_Identity=23.992673992674, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24647160, Length=494, Percent_Identity=23.2793522267206, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21355087, Length=494, Percent_Identity=23.4817813765182, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21358633, Length=429, Percent_Identity=24.9417249417249, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI85815873, Length=464, Percent_Identity=22.8448275862069, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 59867; Mature: 59867

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50801 STAS ; PS00131 CARBOXYPEPT_SER_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRSKHIDAPPQHAAHFAPLDEPPAPRARRTALDALAGLSIAGLLIPEAVAYAGLANLP
CCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PQAGLIALVVGLVVYAIAGSSRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVA
CCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
TTGILFILAGAARLGGMSDFIARPVLRGFTFGLALTIVIKQLPKMLDVPIHHGDTLRVAL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
DLLLGIAGCNVRSAALGAAALAILFALGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEHHHCCEEEE
GTIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTVSPNRDLV
EEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
ALGCANLVSGLLHGMPVGAGYSATSANEAAGAQTRMAGLFAAAVIALIAWLLLPQLARIP
EHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EPVLAAIVIFAVSHSLHPEVFRPYWTWHRDRIVVIAALAAVIVLGVLHGLLAAIGVSLLL
HHHHHHHHHHHHHCCCCHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRQLSEPNVSVLGRLRGSHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
HHHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCEEEECCCCEEEECCHHHHHHHHHH
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLALVRLKPNVLRVLQRA
HHHCCCCCHHHEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHH
ADGGLRADALSELSVDESLQSLTAGELPRA
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDLRSKHIDAPPQHAAHFAPLDEPPAPRARRTALDALAGLSIAGLLIPEAVAYAGLANLP
CCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PQAGLIALVVGLVVYAIAGSSRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVA
CCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
TTGILFILAGAARLGGMSDFIARPVLRGFTFGLALTIVIKQLPKMLDVPIHHGDTLRVAL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
DLLLGIAGCNVRSAALGAAALAILFALGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEHHHCCEEEE
GTIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTVSPNRDLV
EEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
ALGCANLVSGLLHGMPVGAGYSATSANEAAGAQTRMAGLFAAAVIALIAWLLLPQLARIP
EHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EPVLAAIVIFAVSHSLHPEVFRPYWTWHRDRIVVIAALAAVIVLGVLHGLLAAIGVSLLL
HHHHHHHHHHHHHCCCCHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRQLSEPNVSVLGRLRGSHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
HHHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCEEEECCCCEEEECCHHHHHHHHHH
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLALVRLKPNVLRVLQRA
HHHCCCCCHHHEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHH
ADGGLRADALSELSVDESLQSLTAGELPRA
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]