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The map label for this gene is pheS [H]

Identifier: 237812020

GI number: 237812020

Start: 1707399

End: 1708430

Strand: Direct

Name: pheS [H]

Synonym: GBP346_A1761

Alternate gene names: 237812020

Gene position: 1707399-1708430 (Clockwise)

Preceding gene: 237812019

Following gene: 237812021

Centisome position: 41.66

GC content: 63.57

Gene sequence:

>1032_bases
TTGGAAGTGATGGGATCAATGGATCTGGACCAGATTGTCGCCGACGCGCAGCAGTCGTTCGAAGGGGCTGCGGATATCAC
CACGCTCGAGAACGAGAAGGCGCGGTTTCTCGGTAAGTCGGGCGCGCTGACCGAGCTGCTGAAGGGCCTCGGCAAGCTCG
ATCCCGAGACGCGCAAGACGGAAGGCGCGCGCATCAATGTCGCGAAGCAGCAGGTCGAAGCCGCGCTCAACGCGCGCCGC
CAGGCGCTTGCCGACGCGCTCCTGAACCAGCGTCTCGCCGCCGAGGCGATCGACGTCACGCTGCCCGGCCGAGGTGCCGG
GGCGGGAAGCCTCCATCCGGTGATGCGCACGTGGGAGCGTGTCGAACAGATTTTTCGCTCGATCGGTTTCGACGTGGCCG
ACGGCCCCGAGATCGAAACCGACTGGTACAACTTCACCGCATTGAACAGCCCGGAGAATCATCCGGCGCGCTCGATGCAG
GATACGTTCTACGTCGACGGCAAGGACGCGGACGGCCGCCCGCTGCTGCTGCGCACGCACACGAGCCCGATGCAGGTCCG
CTATGCGCGAATGAACCGGCCGCCCATCAAGGTGATCGCGCCGGGCCGCACGTACCGCGTCGACAGCGATGCGACGCACT
CGCCGATGTTCAACCAGGTCGAAGGCTTGTGGATCGACGAGAACGTCAGCTTCGCGGACCTGAAGGGCGTTTATACGGAT
TTCCTGAAGAAATTCTTCGAGCGCGACGACATTCTCGTGCGCTTCCGTCCGTCGTATTTCCCGTTCACCGAGCCGTCGGC
CGAGATCGACATGATGTTCGAGCACGGCAAGAACGCCGGCAAGTGGCTCGAGATTTCCGGTTCCGGCCAGGTGCATCCGA
CCGTGATCCGCAACATGGGGCTCGATCCCGAGCGCTATATCGGTTTCGCGTTCGGCAGCGGCCTCGAGCGGCTGACGATG
CTGCGCTACGGCGTGCAGGATCTGCGCCTGTTCTTCGAGAACGATCTGCGCTTCCTGCGGCAGTTCGCGTAA

Upstream 100 bases:

>100_bases
AGCGATGTTCCGGTAGTCGCGGCCGCTGCAGCGAAAACGGGGCTCTTCCGAGCCCCTTTTTTGTTGGGTCGGGCGTTTCG
CTCGACGAGCACAACGGACG

Downstream 100 bases:

>100_bases
CGGCGCGACCGTCCCGCTCCGCGCCCGGCCGGCCCGTCGAGGCGGCGCGCCGGGCCTCGATCTAATCTGTTTCGAACGTG
GATATCCATGCAATTCCCTG

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MEVMGSMDLDQIVADAQQSFEGAADITTLENEKARFLGKSGALTELLKGLGKLDPETRKTEGARINVAKQQVEAALNARR
QALADALLNQRLAAEAIDVTLPGRGAGAGSLHPVMRTWERVEQIFRSIGFDVADGPEIETDWYNFTALNSPENHPARSMQ
DTFYVDGKDADGRPLLLRTHTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENVSFADLKGVYTD
FLKKFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRNMGLDPERYIGFAFGSGLERLTM
LRYGVQDLRLFFENDLRFLRQFA

Sequences:

>Translated_343_residues
MEVMGSMDLDQIVADAQQSFEGAADITTLENEKARFLGKSGALTELLKGLGKLDPETRKTEGARINVAKQQVEAALNARR
QALADALLNQRLAAEAIDVTLPGRGAGAGSLHPVMRTWERVEQIFRSIGFDVADGPEIETDWYNFTALNSPENHPARSMQ
DTFYVDGKDADGRPLLLRTHTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENVSFADLKGVYTD
FLKKFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRNMGLDPERYIGFAFGSGLERLTM
LRYGVQDLRLFFENDLRFLRQFA
>Mature_343_residues
MEVMGSMDLDQIVADAQQSFEGAADITTLENEKARFLGKSGALTELLKGLGKLDPETRKTEGARINVAKQQVEAALNARR
QALADALLNQRLAAEAIDVTLPGRGAGAGSLHPVMRTWERVEQIFRSIGFDVADGPEIETDWYNFTALNSPENHPARSMQ
DTFYVDGKDADGRPLLLRTHTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENVSFADLKGVYTD
FLKKFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRNMGLDPERYIGFAFGSGLERLTM
LRYGVQDLRLFFENDLRFLRQFA

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=263, Percent_Identity=32.319391634981, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI5729820, Length=290, Percent_Identity=30.6896551724138, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1788007, Length=334, Percent_Identity=57.7844311377245, Blast_Score=385, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI32563657, Length=265, Percent_Identity=33.5849056603774, Blast_Score=141, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17508957, Length=265, Percent_Identity=33.5849056603774, Blast_Score=141, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI32566635, Length=275, Percent_Identity=32, Blast_Score=110, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6321087, Length=267, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6325304, Length=327, Percent_Identity=26.9113149847095, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI18858079, Length=290, Percent_Identity=31.0344827586207, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI17137424, Length=249, Percent_Identity=28.9156626506024, Blast_Score=88, Evalue=7e-18,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 38659; Mature: 38659

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVMGSMDLDQIVADAQQSFEGAADITTLENEKARFLGKSGALTELLKGLGKLDPETRKT
CCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCHHHHHCCCCCHHHHHHHHHCCCCCHHCC
EGARINVAKQQVEAALNARRQALADALLNQRLAAEAIDVTLPGRGAGAGSLHPVMRTWER
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHH
VEQIFRSIGFDVADGPEIETDWYNFTALNSPENHPARSMQDTFYVDGKDADGRPLLLRTH
HHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEC
TSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENVSFADLKGVYTD
CCCHHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCHHHHCCEEEECCCCHHHHHHHHHH
FLKKFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRNMG
HHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHCC
LDPERYIGFAFGSGLERLTMLRYGVQDLRLFFENDLRFLRQFA
CCHHHHEEEHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEVMGSMDLDQIVADAQQSFEGAADITTLENEKARFLGKSGALTELLKGLGKLDPETRKT
CCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCHHHHHCCCCCHHHHHHHHHCCCCCHHCC
EGARINVAKQQVEAALNARRQALADALLNQRLAAEAIDVTLPGRGAGAGSLHPVMRTWER
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHH
VEQIFRSIGFDVADGPEIETDWYNFTALNSPENHPARSMQDTFYVDGKDADGRPLLLRTH
HHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEC
TSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENVSFADLKGVYTD
CCCHHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCHHHHCCEEEECCCCHHHHHHHHHH
FLKKFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRNMG
HHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHCC
LDPERYIGFAFGSGLERLTMLRYGVQDLRLFFENDLRFLRQFA
CCHHHHEEEHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA