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The map label for this gene is yisS [H]

Identifier: 237811966

GI number: 237811966

Start: 1648442

End: 1649479

Strand: Direct

Name: yisS [H]

Synonym: GBP346_A1706

Alternate gene names: 237811966

Gene position: 1648442-1649479 (Clockwise)

Preceding gene: 237811965

Following gene: 237811967

Centisome position: 40.22

GC content: 72.93

Gene sequence:

>1038_bases
ATGACAGTCAGTCACAGCGCCGCTGCGGTGCGCATCGGCATCGCGGGGCTCGGCCGGCTCGGCCGGCGCCACGCGGAGAA
CCTCGCGCGGCGCGTCGCGGGCGCGCGGCTCGCGGCCGCGTGCAGCCCGCTTGCCGACGAGTGCGCGTGGGCGCGCGAGA
CGCTCGCCGTGCCGCGCGTCTACGAGGATTTCGACGCGCTCGCGGCCGATCCCGAGCTCGACGCGCTCTGGCTCGTCACG
CCGTCGGCGCTGCACGCGGACCAGATCGTCGCCGCGTTGCGCGCGGGCAAGCACGTGTTCTGCGAGAAACCGCTGTCGCT
CGATCTCGGCGAATGCGAGCGGGTGCTCGCCGAGGCGCGCGCGCGGCCGCATCTCGTCGCGACGATCGGTTTCATGCGCC
GCTTCGATCCGAGCTATCGCGACGCGTACGCGCGCGTCGCGGCGGGCGAGATCGGCCGGCCGTTCCTCGTGCGCTCGCAG
ACCTGCGACCGGAACGATCCCGAGGGCTTTTTCGTGCGCTTCGCGCCGAGCTCGGGCGGCATCTTCCTCGATTGCACCGT
GCACGACATCGACGTCGCACGATGGCTGCTCGGCGCGCCGCGCGCGACGCGCGTGTACGCGGCGGGCGCGGTCGCGCTGC
ACGAGGGGCTGCGCGCGTGCGGCGACGTCGACAACGGCGTCGCGATCTGCGAGTTCGAAGGCGGCCGGCTCGCGATGTTC
TATGCGTCGCGCACGATGGCGCACGGCAACGACACGCACTCCGAAGTGATCGGCACGGCGGGCGCGCTCGCGATCGGCCG
CAACCCGCGCGCGGACCGCGTCGAGATCTATGATGCGGCGGGCATCCGCAACACCTGCACGCCGACGTTCTTCGACCGCT
TCGAGGATGCGTTCCTGATCGAGGCGCAGGCGTTCGTCGCGGCGGTGCGCGGCGAGGGCGCCGCCGGCGGCGCGACGCTC
GCGGACGCGCTCGAGGCGACGAGGATCGGCCATGCGCTGCGCGAATCGTTGCAGACCGGGCGGGCGATCGAGCTGTAG

Upstream 100 bases:

>100_bases
CGGCGTGAAGGCGCTCGAGCTCGCCGAGGCGGCGACGCTGTCGTGGCGCGAGGCCCGCGCGGTGACGCTCGGCGAGCGGG
CGGCCTGAAGGAGCGATGCG

Downstream 100 bases:

>100_bases
CCCGACGTGCGCGCGCCGCACGGCGGGCAGCGCGGGCGCGCTCGCACGCCGGCCCCGCCCGCGCCGGCGTTTGCGCGCGC
GCGGGGGGCGCGCGCGAGCG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTVSHSAAAVRIGIAGLGRLGRRHAENLARRVAGARLAAACSPLADECAWARETLAVPRVYEDFDALAADPELDALWLVT
PSALHADQIVAALRAGKHVFCEKPLSLDLGECERVLAEARARPHLVATIGFMRRFDPSYRDAYARVAAGEIGRPFLVRSQ
TCDRNDPEGFFVRFAPSSGGIFLDCTVHDIDVARWLLGAPRATRVYAAGAVALHEGLRACGDVDNGVAICEFEGGRLAMF
YASRTMAHGNDTHSEVIGTAGALAIGRNPRADRVEIYDAAGIRNTCTPTFFDRFEDAFLIEAQAFVAAVRGEGAAGGATL
ADALEATRIGHALRESLQTGRAIEL

Sequences:

>Translated_345_residues
MTVSHSAAAVRIGIAGLGRLGRRHAENLARRVAGARLAAACSPLADECAWARETLAVPRVYEDFDALAADPELDALWLVT
PSALHADQIVAALRAGKHVFCEKPLSLDLGECERVLAEARARPHLVATIGFMRRFDPSYRDAYARVAAGEIGRPFLVRSQ
TCDRNDPEGFFVRFAPSSGGIFLDCTVHDIDVARWLLGAPRATRVYAAGAVALHEGLRACGDVDNGVAICEFEGGRLAMF
YASRTMAHGNDTHSEVIGTAGALAIGRNPRADRVEIYDAAGIRNTCTPTFFDRFEDAFLIEAQAFVAAVRGEGAAGGATL
ADALEATRIGHALRESLQTGRAIEL
>Mature_344_residues
TVSHSAAAVRIGIAGLGRLGRRHAENLARRVAGARLAAACSPLADECAWARETLAVPRVYEDFDALAADPELDALWLVTP
SALHADQIVAALRAGKHVFCEKPLSLDLGECERVLAEARARPHLVATIGFMRRFDPSYRDAYARVAAGEIGRPFLVRSQT
CDRNDPEGFFVRFAPSSGGIFLDCTVHDIDVARWLLGAPRATRVYAAGAVALHEGLRACGDVDNGVAICEFEGGRLAMFY
ASRTMAHGNDTHSEVIGTAGALAIGRNPRADRVEIYDAAGIRNTCTPTFFDRFEDAFLIEAQAFVAAVRGEGAAGGATLA
DALEATRIGHALRESLQTGRAIEL

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787307, Length=190, Percent_Identity=31.0526315789474, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787574, Length=210, Percent_Identity=24.2857142857143, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581117, Length=211, Percent_Identity=25.1184834123223, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: NA

Molecular weight: Translated: 36912; Mature: 36781

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSHSAAAVRIGIAGLGRLGRRHAENLARRVAGARLAAACSPLADECAWARETLAVPRV
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHH
YEDFDALAADPELDALWLVTPSALHADQIVAALRAGKHVFCEKPLSLDLGECERVLAEAR
HHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHC
ARPHLVATIGFMRRFDPSYRDAYARVAAGEIGRPFLVRSQTCDRNDPEGFFVRFAPSSGG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEECCCCC
IFLDCTVHDIDVARWLLGAPRATRVYAAGAVALHEGLRACGDVDNGVAICEFEGGRLAMF
EEEEEEECHHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEE
YASRTMAHGNDTHSEVIGTAGALAIGRNPRADRVEIYDAAGIRNTCTPTFFDRFEDAFLI
EEEHHHCCCCCCHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCEEE
EAQAFVAAVRGEGAAGGATLADALEATRIGHALRESLQTGRAIEL
EHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVSHSAAAVRIGIAGLGRLGRRHAENLARRVAGARLAAACSPLADECAWARETLAVPRV
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHH
YEDFDALAADPELDALWLVTPSALHADQIVAALRAGKHVFCEKPLSLDLGECERVLAEAR
HHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHC
ARPHLVATIGFMRRFDPSYRDAYARVAAGEIGRPFLVRSQTCDRNDPEGFFVRFAPSSGG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEECCCCC
IFLDCTVHDIDVARWLLGAPRATRVYAAGAVALHEGLRACGDVDNGVAICEFEGGRLAMF
EEEEEEECHHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEE
YASRTMAHGNDTHSEVIGTAGALAIGRNPRADRVEIYDAAGIRNTCTPTFFDRFEDAFLI
EEEHHHCCCCCCHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCEEE
EAQAFVAAVRGEGAAGGATLADALEATRIGHALRESLQTGRAIEL
EHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377; 8407808 [H]