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The map label for this gene is iolC1 [H]

Identifier: 237811960

GI number: 237811960

Start: 1641169

End: 1643169

Strand: Reverse

Name: iolC1 [H]

Synonym: GBP346_A1700

Alternate gene names: 237811960

Gene position: 1643169-1641169 (Counterclockwise)

Preceding gene: 237811961

Following gene: 237811959

Centisome position: 40.09

GC content: 72.06

Gene sequence:

>2001_bases
ATGACTTCCCCTACCCTTTCCTTTGCGCAGAATCGCCCGCTCGACGTGATCTGCGTCGGCCGCGTCGCCGTCGATCTGTA
CGCGCAGCAGATCGGCGCGCGGCTCGAGGACGCGTCGAGCTTCGCGAAATATCTCGGCGGCTCGTCGGGCAACATCGCGT
TCGGCTGCGCGCGGCTCGGCCTCAAATCGGCGATGCTCTCGCGCGTCGGCCACGATCACATGGGCCGCTTCGTGCGCGAG
ACGCTCGCGCGCGAAGGCTGCGACACGAGCCGGCTGCGCACCGACACCGAGCGCCTGACCGCGCTCGTGCTGCTCGGCCT
GAAGAACCGCGACACGTTCCCGCTGATCTTCCATCGCGAGAACTGCGCGGACATGGCGCTCGACGAGGACGACTTCGACG
AGGCGTTCATCGCTTCGTCGAAGGCGCTCCTCATCACCGGCACGCACTTCTCGACCGAGCAGGTGATGCGCGCGAGCCGC
CGCGCGCTCGACTACGCGCGCCGCAACCAGGTGCGCACCGTGCTCGACATCGACTATCGCCCCGTGCTCTGGGGCCTGAC
GGGCAAGGCCGACGGCGAGACGCGCTTCATCGCGAACGAAGGCGTGACCGCGCATCTGCAGCGGATCCTGCCGCTGTTCG
ACGTCGTGATCGGCACCGAGGAGGAATTCCGCATCGCGGGCGGCAAGGACGCGCTCCTCGACGCGCTCGCGATGGTGCGC
GCGGTGACGAGCGCCGCGCTCGTCGTCAAGCGCGGGCCGCTCGGCTGCTCGATCGTCGACGGCGACGTGCCCGCGACGCT
CGACGCGCTGCCCGTCATCCGCGGCGTCGAAGTCGACGTGATGAACGTGCTCGGCGCGGGCGACGCGTTCGCATCGGGCT
TCCTGTCGCAGTGGCTGCGCGGGCGGCCGTTCGCCGACGCGGCGCGCGCGGCGAACGCGTGCGGCGCGCTCGTCGTGTCG
CGGCACGGCTGCTCGCCCGCGATGCCGACGCCCGCCGAGCTCGCGTATTTCCTCGCCGAGGCGAAGCGCGATCCCGCGCG
GATGCGCCGCCCCGATCTCGACGCGACGCTCGCGCGGCTGCACCGCGTGACGCCCGCGCGCACGCCGCGCGGCGAAGTGC
TCGGCTTCGCGTTCGATCACCGCAATCAGTTCTTCGAGCTCGCGCGTCAAACGGGCGCGAGCGTCGCGCGCATCGATGCG
CTCAAGCGCCTGTTCGTCGAGGCGGTCGCGCAGACGGAGGCGCAGCTCGGGCTCGCCGGGCGCATCGGCGTGCTGATCGA
CGACCGCTATGGCCAGGACGCGCTGAACGACGCGACGGGCCGCGGCTGGTGGGTCGGCCGCCCGGTCGAGCTGCCGGGTT
CGCTGCCGCTCGAATTCGATCACGGCCGCTCGATCGGCACGACGCTCGCGTCGTGGCCCCTGGAGCACGTCGCGAAGTGT
CTCGTCCAATACCATCCGGACGAGGCCGCCGAGCCGCGCATCGAACAGGAAACGCAGTTGCGCGCGCTGTACGACGCGGT
GCAGGCGAGCGGCCACGAGCTGCTGCTCGAAGTGATCCCGCCGCGCCGCGCGGATCTGCCGCAGGCGGCCGACACCGTGT
ACCGCGCGCTCAAGCGCCTGTACAACCTCGGCATCCATCCGGAATGGTGGAAGCTCGCGCCGCTCGACGCCGCGCAATGG
CAGGCGATCGACGCGCTGATCGCCGAGCGCGATCCGTACTGCCGCGGCGTCGTGCTGCTCGGCCTGTCGGCGGGCGTCGA
CGAGCTCGTCGGCGGCTTCGGCGCGGCGGCCGCGTCCGCGACGTGCCGCGGCTTCACGGTGGGCCGCACGATCTTCCACG
AACCGAGCCGCGCCTGGCTCGCGGGCGAGATCGACGATGCCGAGCTGATCGCGCGCGTGCGGCGCACTTTCGAGACGCTG
ATCGGCGCGTGGCGCGCGGCCCGCACGGACGCCCGCGCGCGCGGCCGCCACGCCGGCGCCGCGCCGCGCGTGGCCGCCTA
G

Upstream 100 bases:

>100_bases
ATCAGCAAGAACGAGGTGCTCGACATGATGGCGGGCGGCGCCGAGATGCAGAAGATGATCGCCGAACTCGACGGCGCGAC
CATTTGACCCAGGATTCGCG

Downstream 100 bases:

>100_bases
GAGCCGCGCGATGAATCGCAGAGCAATGGATGACGACACCCGACGGAGCCCGAGCGTGAACGACTTCATCGACGATCCGG
CCGCGAGCGTGCAACGCACG

Product: IolC protein

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase 1; DKG kinase 1 [H]

Number of amino acids: Translated: 666; Mature: 665

Protein sequence:

>666_residues
MTSPTLSFAQNRPLDVICVGRVAVDLYAQQIGARLEDASSFAKYLGGSSGNIAFGCARLGLKSAMLSRVGHDHMGRFVRE
TLAREGCDTSRLRTDTERLTALVLLGLKNRDTFPLIFHRENCADMALDEDDFDEAFIASSKALLITGTHFSTEQVMRASR
RALDYARRNQVRTVLDIDYRPVLWGLTGKADGETRFIANEGVTAHLQRILPLFDVVIGTEEEFRIAGGKDALLDALAMVR
AVTSAALVVKRGPLGCSIVDGDVPATLDALPVIRGVEVDVMNVLGAGDAFASGFLSQWLRGRPFADAARAANACGALVVS
RHGCSPAMPTPAELAYFLAEAKRDPARMRRPDLDATLARLHRVTPARTPRGEVLGFAFDHRNQFFELARQTGASVARIDA
LKRLFVEAVAQTEAQLGLAGRIGVLIDDRYGQDALNDATGRGWWVGRPVELPGSLPLEFDHGRSIGTTLASWPLEHVAKC
LVQYHPDEAAEPRIEQETQLRALYDAVQASGHELLLEVIPPRRADLPQAADTVYRALKRLYNLGIHPEWWKLAPLDAAQW
QAIDALIAERDPYCRGVVLLGLSAGVDELVGGFGAAAASATCRGFTVGRTIFHEPSRAWLAGEIDDAELIARVRRTFETL
IGAWRAARTDARARGRHAGAAPRVAA

Sequences:

>Translated_666_residues
MTSPTLSFAQNRPLDVICVGRVAVDLYAQQIGARLEDASSFAKYLGGSSGNIAFGCARLGLKSAMLSRVGHDHMGRFVRE
TLAREGCDTSRLRTDTERLTALVLLGLKNRDTFPLIFHRENCADMALDEDDFDEAFIASSKALLITGTHFSTEQVMRASR
RALDYARRNQVRTVLDIDYRPVLWGLTGKADGETRFIANEGVTAHLQRILPLFDVVIGTEEEFRIAGGKDALLDALAMVR
AVTSAALVVKRGPLGCSIVDGDVPATLDALPVIRGVEVDVMNVLGAGDAFASGFLSQWLRGRPFADAARAANACGALVVS
RHGCSPAMPTPAELAYFLAEAKRDPARMRRPDLDATLARLHRVTPARTPRGEVLGFAFDHRNQFFELARQTGASVARIDA
LKRLFVEAVAQTEAQLGLAGRIGVLIDDRYGQDALNDATGRGWWVGRPVELPGSLPLEFDHGRSIGTTLASWPLEHVAKC
LVQYHPDEAAEPRIEQETQLRALYDAVQASGHELLLEVIPPRRADLPQAADTVYRALKRLYNLGIHPEWWKLAPLDAAQW
QAIDALIAERDPYCRGVVLLGLSAGVDELVGGFGAAAASATCRGFTVGRTIFHEPSRAWLAGEIDDAELIARVRRTFETL
IGAWRAARTDARARGRHAGAAPRVAA
>Mature_665_residues
TSPTLSFAQNRPLDVICVGRVAVDLYAQQIGARLEDASSFAKYLGGSSGNIAFGCARLGLKSAMLSRVGHDHMGRFVRET
LAREGCDTSRLRTDTERLTALVLLGLKNRDTFPLIFHRENCADMALDEDDFDEAFIASSKALLITGTHFSTEQVMRASRR
ALDYARRNQVRTVLDIDYRPVLWGLTGKADGETRFIANEGVTAHLQRILPLFDVVIGTEEEFRIAGGKDALLDALAMVRA
VTSAALVVKRGPLGCSIVDGDVPATLDALPVIRGVEVDVMNVLGAGDAFASGFLSQWLRGRPFADAARAANACGALVVSR
HGCSPAMPTPAELAYFLAEAKRDPARMRRPDLDATLARLHRVTPARTPRGEVLGFAFDHRNQFFELARQTGASVARIDAL
KRLFVEAVAQTEAQLGLAGRIGVLIDDRYGQDALNDATGRGWWVGRPVELPGSLPLEFDHGRSIGTTLASWPLEHVAKCL
VQYHPDEAAEPRIEQETQLRALYDAVQASGHELLLEVIPPRRADLPQAADTVYRALKRLYNLGIHPEWWKLAPLDAAQWQ
AIDALIAERDPYCRGVVLLGLSAGVDELVGGFGAAAASATCRGFTVGRTIFHEPSRAWLAGEIDDAELIARVRRTFETLI
GAWRAARTDARARGRHAGAAPRVAA

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=332, Percent_Identity=27.1084337349398, Blast_Score=93, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17541820, Length=134, Percent_Identity=34.3283582089552, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 72458; Mature: 72327

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPTLSFAQNRPLDVICVGRVAVDLYAQQIGARLEDASSFAKYLGGSSGNIAFGCARLG
CCCCCCCHHCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEHHHHHHH
LKSAMLSRVGHDHMGRFVRETLAREGCDTSRLRTDTERLTALVLLGLKNRDTFPLIFHRE
HHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCCCEEEEECC
NCADMALDEDDFDEAFIASSKALLITGTHFSTEQVMRASRRALDYARRNQVRTVLDIDYR
CCHHCCCCCCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCC
PVLWGLTGKADGETRFIANEGVTAHLQRILPLFDVVIGTEEEFRIAGGKDALLDALAMVR
CEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHH
AVTSAALVVKRGPLGCSIVDGDVPATLDALPVIRGVEVDVMNVLGAGDAFASGFLSQWLR
HHHHHHHHEECCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHC
GRPFADAARAANACGALVVSRHGCSPAMPTPAELAYFLAEAKRDPARMRRPDLDATLARL
CCCCHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHH
HRVTPARTPRGEVLGFAFDHRNQFFELARQTGASVARIDALKRLFVEAVAQTEAQLGLAG
HHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
RIGVLIDDRYGQDALNDATGRGWWVGRPVELPGSLPLEFDHGRSIGTTLASWPLEHVAKC
CEEEEEECCCCCHHHCCCCCCCEECCCCCCCCCCCCEEECCCCCHHHHHHHCCHHHHHHH
LVQYHPDEAAEPRIEQETQLRALYDAVQASGHELLLEVIPPRRADLPQAADTVYRALKRL
HHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
YNLGIHPEWWKLAPLDAAQWQAIDALIAERDPYCRGVVLLGLSAGVDELVGGFGAAAASA
HHCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHC
TCRGFTVGRTIFHEPSRAWLAGEIDDAELIARVRRTFETLIGAWRAARTDARARGRHAGA
CCCCEECCHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCC
APRVAA
CCCCCC
>Mature Secondary Structure 
TSPTLSFAQNRPLDVICVGRVAVDLYAQQIGARLEDASSFAKYLGGSSGNIAFGCARLG
CCCCCCHHCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEHHHHHHH
LKSAMLSRVGHDHMGRFVRETLAREGCDTSRLRTDTERLTALVLLGLKNRDTFPLIFHRE
HHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCCCEEEEECC
NCADMALDEDDFDEAFIASSKALLITGTHFSTEQVMRASRRALDYARRNQVRTVLDIDYR
CCHHCCCCCCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCC
PVLWGLTGKADGETRFIANEGVTAHLQRILPLFDVVIGTEEEFRIAGGKDALLDALAMVR
CEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHH
AVTSAALVVKRGPLGCSIVDGDVPATLDALPVIRGVEVDVMNVLGAGDAFASGFLSQWLR
HHHHHHHHEECCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHC
GRPFADAARAANACGALVVSRHGCSPAMPTPAELAYFLAEAKRDPARMRRPDLDATLARL
CCCCHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHH
HRVTPARTPRGEVLGFAFDHRNQFFELARQTGASVARIDALKRLFVEAVAQTEAQLGLAG
HHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
RIGVLIDDRYGQDALNDATGRGWWVGRPVELPGSLPLEFDHGRSIGTTLASWPLEHVAKC
CEEEEEECCCCCHHHCCCCCCCEECCCCCCCCCCCCEEECCCCCHHHHHHHCCHHHHHHH
LVQYHPDEAAEPRIEQETQLRALYDAVQASGHELLLEVIPPRRADLPQAADTVYRALKRL
HHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
YNLGIHPEWWKLAPLDAAQWQAIDALIAERDPYCRGVVLLGLSAGVDELVGGFGAAAASA
HHCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHC
TCRGFTVGRTIFHEPSRAWLAGEIDDAELIARVRRTFETLIGAWRAARTDARARGRHAGA
CCCCEECCHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCC
APRVAA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA