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The map label for this gene is abgR [H]

Identifier: 237811856

GI number: 237811856

Start: 1535436

End: 1536413

Strand: Direct

Name: abgR [H]

Synonym: GBP346_A1596

Alternate gene names: 237811856

Gene position: 1535436-1536413 (Clockwise)

Preceding gene: 237811855

Following gene: 237811857

Centisome position: 37.46

GC content: 66.26

Gene sequence:

>978_bases
ATGGCCGCTGAATGGATGGGCTGCGACCGGTTTCGCGCAAATTCGATGAAAGTATCGCTGCGTCATTTACGTGCGTTCGT
GGCGGTGGCTCGGGAAGGCAGCTTCACGGCCGCCGCGGGCGCGCTGTGCCTCACGCAGTCGACGCTGACGAAGACGATCC
GCGAGTTCGAACAGGCGCTCGGCGTGCACGTGTTCGAGCGCAATACGCGGCGCATCGCGCTCACGCCGTACGGCGCGGCG
TTCCTCGTCGACGCGGTGAGAATCCTGAACGACCTCGATCTCGCGCTCGACGGCGTCAACCAGCAACTCCTCGGAAACAG
CGGCACCGTACGCGTCGCAAGCGGCCTCGCGTTCGCGTCGACGGTCATGCCGTGCGTGATCCGGGCCTTGCACGCGCAGG
AGCCCGGCATTCACGTGGATTTGCTCGACGACACGAGTGGCGGCGTGATCCGGCGGATCGAATCCGGCGAGGTCGACGTG
GGGATCGGCTCGTACGTCGGCATGGCCGGCAACGCGCTGAGCGTGAGGCGCATCCTGAGCGCGCGTCTGGGCGTGCTGTT
TCCGGTCGGCTATCCGAAGATTCCGTCGCGGCCCACGCTCGCCAGCCTGAACGAGATTCCGATCCTGCGCGACTCGGACG
AGTCGAGCATTGCCGCCGCGTTTCGGCAGCAGGCGCCCGATCTCTGGGAGCGGATGAGGCGAAAGGTGTCCGTCACGAAT
CTCGATTTGCAGCTCGCGCTGGTTCGCGAGGGCATCGGCGCGTGCATCGTGTCGGCATTGGCGGCGTCGCATCCGTCCGC
GCGGGGGATGCCGTATCGCCTGCTCGTCGAGCCGGAAATGACGCGGGACGTCTATGTGTTCACTCGCCGCGACGTGTCGC
TGCTGCCGGCCGCCGCGCGGTTCGTCGACATTCTGATGAACGTGCTTCCGTCGATCGATTTCGCCGAGGGCGTCGTACTC
GCTTGCGACGGCGCGTGA

Upstream 100 bases:

>100_bases
GCGCGGCGCGATGCTAGTATCAAGAACTCGGGACAAGGTAAATTCATGGCCGGTTGGACGTTTGGCGGTGCAATGAGCGC
GGTGTCGCAAAGGCGGGCTC

Downstream 100 bases:

>100_bases
ACGCCACGCGCCGCGCCGCGCCGCTCCCGCGCCGTCGCGCCGTCGCGCCGTCGCGCCGCGAGCGTGCGGCGCGACAGCCC
TTGCCGGCCGTTGTCGAACC

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAAEWMGCDRFRANSMKVSLRHLRAFVAVAREGSFTAAAGALCLTQSTLTKTIREFEQALGVHVFERNTRRIALTPYGAA
FLVDAVRILNDLDLALDGVNQQLLGNSGTVRVASGLAFASTVMPCVIRALHAQEPGIHVDLLDDTSGGVIRRIESGEVDV
GIGSYVGMAGNALSVRRILSARLGVLFPVGYPKIPSRPTLASLNEIPILRDSDESSIAAAFRQQAPDLWERMRRKVSVTN
LDLQLALVREGIGACIVSALAASHPSARGMPYRLLVEPEMTRDVYVFTRRDVSLLPAAARFVDILMNVLPSIDFAEGVVL
ACDGA

Sequences:

>Translated_325_residues
MAAEWMGCDRFRANSMKVSLRHLRAFVAVAREGSFTAAAGALCLTQSTLTKTIREFEQALGVHVFERNTRRIALTPYGAA
FLVDAVRILNDLDLALDGVNQQLLGNSGTVRVASGLAFASTVMPCVIRALHAQEPGIHVDLLDDTSGGVIRRIESGEVDV
GIGSYVGMAGNALSVRRILSARLGVLFPVGYPKIPSRPTLASLNEIPILRDSDESSIAAAFRQQAPDLWERMRRKVSVTN
LDLQLALVREGIGACIVSALAASHPSARGMPYRLLVEPEMTRDVYVFTRRDVSLLPAAARFVDILMNVLPSIDFAEGVVL
ACDGA
>Mature_324_residues
AAEWMGCDRFRANSMKVSLRHLRAFVAVAREGSFTAAAGALCLTQSTLTKTIREFEQALGVHVFERNTRRIALTPYGAAF
LVDAVRILNDLDLALDGVNQQLLGNSGTVRVASGLAFASTVMPCVIRALHAQEPGIHVDLLDDTSGGVIRRIESGEVDVG
IGSYVGMAGNALSVRRILSARLGVLFPVGYPKIPSRPTLASLNEIPILRDSDESSIAAAFRQQAPDLWERMRRKVSVTNL
DLQLALVREGIGACIVSALAASHPSARGMPYRLLVEPEMTRDVYVFTRRDVSLLPAAARFVDILMNVLPSIDFAEGVVLA
CDGA

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=184, Percent_Identity=28.804347826087, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693105, Length=300, Percent_Identity=26.6666666666667, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081904, Length=149, Percent_Identity=34.8993288590604, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI157672245, Length=296, Percent_Identity=25, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788748, Length=165, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788887, Length=249, Percent_Identity=26.1044176706827, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082132, Length=178, Percent_Identity=32.5842696629214, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787879, Length=198, Percent_Identity=28.7878787878788, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787589, Length=122, Percent_Identity=33.6065573770492, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788296, Length=195, Percent_Identity=27.1794871794872, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787128, Length=131, Percent_Identity=28.2442748091603, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788626, Length=162, Percent_Identity=29.6296296296296, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35071; Mature: 34940

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAEWMGCDRFRANSMKVSLRHLRAFVAVAREGSFTAAAGALCLTQSTLTKTIREFEQAL
CCCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GVHVFERNTRRIALTPYGAAFLVDAVRILNDLDLALDGVNQQLLGNSGTVRVASGLAFAS
CEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEECCHHHHH
TVMPCVIRALHAQEPGIHVDLLDDTSGGVIRRIESGEVDVGIGSYVGMAGNALSVRRILS
HHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCEEECCCHHHCCCCCHHHHHHHHH
ARLGVLFPVGYPKIPSRPTLASLNEIPILRDSDESSIAAAFRQQAPDLWERMRRKVSVTN
HHHCEEEECCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHCCHHHHHHHHHHCCCCC
LDLQLALVREGIGACIVSALAASHPSARGMPYRLLVEPEMTRDVYVFTRRDVSLLPAAAR
CCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHHH
FVDILMNVLPSIDFAEGVVLACDGA
HHHHHHHHHCCCCCCCCEEEEECCC
>Mature Secondary Structure 
AAEWMGCDRFRANSMKVSLRHLRAFVAVAREGSFTAAAGALCLTQSTLTKTIREFEQAL
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GVHVFERNTRRIALTPYGAAFLVDAVRILNDLDLALDGVNQQLLGNSGTVRVASGLAFAS
CEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEECCHHHHH
TVMPCVIRALHAQEPGIHVDLLDDTSGGVIRRIESGEVDVGIGSYVGMAGNALSVRRILS
HHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCEEECCCHHHCCCCCHHHHHHHHH
ARLGVLFPVGYPKIPSRPTLASLNEIPILRDSDESSIAAAFRQQAPDLWERMRRKVSVTN
HHHCEEEECCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHCCHHHHHHHHHHCCCCC
LDLQLALVREGIGACIVSALAASHPSARGMPYRLLVEPEMTRDVYVFTRRDVSLLPAAAR
CCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHHH
FVDILMNVLPSIDFAEGVVLACDGA
HHHHHHHHHCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]