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The map label for this gene is mocR [H]

Identifier: 237811833

GI number: 237811833

Start: 1508250

End: 1509710

Strand: Reverse

Name: mocR [H]

Synonym: GBP346_A1573

Alternate gene names: 237811833

Gene position: 1509710-1508250 (Counterclockwise)

Preceding gene: 237811834

Following gene: 237811830

Centisome position: 36.83

GC content: 67.21

Gene sequence:

>1461_bases
ATGGTTGAGACGCTCGCCGGTTTATTCGATTTCGAGATGGACCCGCAAAGCGGCGTGGCGCTCACGCGGCAGCTCCGTGA
CCAGCTAAGGCGCGCCATCGCGGCGGGTTCGCTTGCAAGCGGCAGGCGTTTGCCTTCCAGCCGGGCACTCGCGCTCCATC
TGCGCGTGTCGAGAAACACCGTCTGCGCCGCCATCGAGCAGTTGGCGATGGAAGGCTATCTCGATGTCTCGAGAGGACGC
CGCCCGGTCGTGGCGCCGATGCCGTCGGCGGGCCTCGTCGCCATCGGCTCGGACAGGCCTGTTTCGGACGGCCGCAGCGG
AATGTCGCAGTGGGCGCAGCGGATCGACCGGAGCGATTGGCCGTTCATCGGCGAGGGGCGCCCGACGCCATTCGCGCCCT
GCGTGGCCGATGCCCGGGCGTTTCCGCACGCGATCTGGGGGCGATGCCTGCGCACGGCCACCCGCTACGCCGTCGCGCGA
ACGAGCACCGCGTGCAACCGGCCCGGGTTACGCAGAGCCCTGTTGCATCACCTCGTCGAATACCGCGGCGTCAACGCGGA
TGCGCACCAGGTCTTCCTGATGCCCACCGCTCAGGCGGCCATCGCGCTCGTCGCACGCGTGCTCCTGGATCCGGGTGACC
TCGCGTGGGTCGAAAGCCCGGGTTACGGCGGCGCACGGGCGGCGTTCGAAGCGGCGGGCGCGACGGTGCAAGGCATCGCG
CTCGATCAAAGCGGCATGGCGTTCGAAACGTCGACGGATACCCCGCGCCTGATATTCGTCACGCCCGCGCACCAGCATCC
GACGGGATTGCTGATGCCGCCTGCCCGTCGACAAGCGCTGCTGCGGTTCGCCGCTCGAGTCGGCGCCCGGATCATCGAGG
ACGACTACGACAGCGAATTTCATTACGAAGGGCGCCCGGTGGCCGCGCTGCAGGGTGCCGACGACGCAGACAGCGTGTTT
TACGTCGGCACGTTCTCGAAATCGCTGCACGCCGACATTCGAGTGGGTTACGTCGTCGTACCGGGGCACTTCGTCGACGT
ATTTGCCAAGGCACAACGGCACACCGGCCAGATCGTCGGCGCGACGCTACAGGATGCGTTGGCCGAGTTCATCGACGACG
GACATTACGCCGCTCACATCCGCAAGACGACGCGCCTCTATCACGCTCGACGCGATTACCTGTGCGATGCGTTGAAGGCC
GTCGGGAGCGAGTTGACCGTATCGCCGCCGGATGGCGGTATGCAGGTGGTAGCCCGGCTCGGGCCCCTGCGCGACGATCG
CGAGATATGCCGCCGCCTGGCCGAAGCGGGCGTGACGGCGCGCCCGCTTTCGCCCCATTACTGCGCGCAAACCGGCGCCC
AAGGGCTATTCCTCGGCTTCGCGGCCTGGAACGAATGCGAGATCGACGCAGGCGTGCGGATTCTCGCTCGCGTGATTCGC
GAGCCGGAGCCATCGAAATAG

Upstream 100 bases:

>100_bases
GCGCCGCGAAGGCGCGCGCCGCGGCGAAAGTCGATACGACTATAGGTTTGACCGGTATTTCCCGGAAGGGTATGTTTTTG
TAAAAACATGGGGCCAGTTT

Downstream 100 bases:

>100_bases
CGATTCGCCCCGCCGGCCGGCGGCGCCCGTGGCCGAACCGGCCGCCCGGGGAAACCGGACGCGCCGTTAGACGGTTGCCA
GAATCAGGCGCGCCGGCGTC

Product: transcriptional regulator, GntR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MVETLAGLFDFEMDPQSGVALTRQLRDQLRRAIAAGSLASGRRLPSSRALALHLRVSRNTVCAAIEQLAMEGYLDVSRGR
RPVVAPMPSAGLVAIGSDRPVSDGRSGMSQWAQRIDRSDWPFIGEGRPTPFAPCVADARAFPHAIWGRCLRTATRYAVAR
TSTACNRPGLRRALLHHLVEYRGVNADAHQVFLMPTAQAAIALVARVLLDPGDLAWVESPGYGGARAAFEAAGATVQGIA
LDQSGMAFETSTDTPRLIFVTPAHQHPTGLLMPPARRQALLRFAARVGARIIEDDYDSEFHYEGRPVAALQGADDADSVF
YVGTFSKSLHADIRVGYVVVPGHFVDVFAKAQRHTGQIVGATLQDALAEFIDDGHYAAHIRKTTRLYHARRDYLCDALKA
VGSELTVSPPDGGMQVVARLGPLRDDREICRRLAEAGVTARPLSPHYCAQTGAQGLFLGFAAWNECEIDAGVRILARVIR
EPEPSK

Sequences:

>Translated_486_residues
MVETLAGLFDFEMDPQSGVALTRQLRDQLRRAIAAGSLASGRRLPSSRALALHLRVSRNTVCAAIEQLAMEGYLDVSRGR
RPVVAPMPSAGLVAIGSDRPVSDGRSGMSQWAQRIDRSDWPFIGEGRPTPFAPCVADARAFPHAIWGRCLRTATRYAVAR
TSTACNRPGLRRALLHHLVEYRGVNADAHQVFLMPTAQAAIALVARVLLDPGDLAWVESPGYGGARAAFEAAGATVQGIA
LDQSGMAFETSTDTPRLIFVTPAHQHPTGLLMPPARRQALLRFAARVGARIIEDDYDSEFHYEGRPVAALQGADDADSVF
YVGTFSKSLHADIRVGYVVVPGHFVDVFAKAQRHTGQIVGATLQDALAEFIDDGHYAAHIRKTTRLYHARRDYLCDALKA
VGSELTVSPPDGGMQVVARLGPLRDDREICRRLAEAGVTARPLSPHYCAQTGAQGLFLGFAAWNECEIDAGVRILARVIR
EPEPSK
>Mature_486_residues
MVETLAGLFDFEMDPQSGVALTRQLRDQLRRAIAAGSLASGRRLPSSRALALHLRVSRNTVCAAIEQLAMEGYLDVSRGR
RPVVAPMPSAGLVAIGSDRPVSDGRSGMSQWAQRIDRSDWPFIGEGRPTPFAPCVADARAFPHAIWGRCLRTATRYAVAR
TSTACNRPGLRRALLHHLVEYRGVNADAHQVFLMPTAQAAIALVARVLLDPGDLAWVESPGYGGARAAFEAAGATVQGIA
LDQSGMAFETSTDTPRLIFVTPAHQHPTGLLMPPARRQALLRFAARVGARIIEDDYDSEFHYEGRPVAALQGADDADSVF
YVGTFSKSLHADIRVGYVVVPGHFVDVFAKAQRHTGQIVGATLQDALAEFIDDGHYAAHIRKTTRLYHARRDYLCDALKA
VGSELTVSPPDGGMQVVARLGPLRDDREICRRLAEAGVTARPLSPHYCAQTGAQGLFLGFAAWNECEIDAGVRILARVIR
EPEPSK

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=308, Percent_Identity=21.4285714285714, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI33469970, Length=308, Percent_Identity=21.4285714285714, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1787710, Length=409, Percent_Identity=25.9168704156479, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790797, Length=428, Percent_Identity=25.9345794392523, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52684; Mature: 52684

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVETLAGLFDFEMDPQSGVALTRQLRDQLRRAIAAGSLASGRRLPSSRALALHLRVSRNT
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCH
VCAAIEQLAMEGYLDVSRGRRPVVAPMPSAGLVAIGSDRPVSDGRSGMSQWAQRIDRSDW
HHHHHHHHHHHCCHHHCCCCCCEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCC
PFIGEGRPTPFAPCVADARAFPHAIWGRCLRTATRYAVARTSTACNRPGLRRALLHHLVE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
YRGVNADAHQVFLMPTAQAAIALVARVLLDPGDLAWVESPGYGGARAAFEAAGATVQGIA
HCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCCEEEEEE
LDQSGMAFETSTDTPRLIFVTPAHQHPTGLLMPPARRQALLRFAARVGARIIEDDYDSEF
ECCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCE
HYEGRPVAALQGADDADSVFYVGTFSKSLHADIRVGYVVVPGHFVDVFAKAQRHTGQIVG
EECCCCEEEECCCCCCCCEEEEEECCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCEEH
ATLQDALAEFIDDGHYAAHIRKTTRLYHARRDYLCDALKAVGSELTVSPPDGGMQVVARL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHH
GPLRDDREICRRLAEAGVTARPLSPHYCAQTGAQGLFLGFAAWNECEIDAGVRILARVIR
CCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHC
EPEPSK
CCCCCC
>Mature Secondary Structure
MVETLAGLFDFEMDPQSGVALTRQLRDQLRRAIAAGSLASGRRLPSSRALALHLRVSRNT
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCH
VCAAIEQLAMEGYLDVSRGRRPVVAPMPSAGLVAIGSDRPVSDGRSGMSQWAQRIDRSDW
HHHHHHHHHHHCCHHHCCCCCCEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCC
PFIGEGRPTPFAPCVADARAFPHAIWGRCLRTATRYAVARTSTACNRPGLRRALLHHLVE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
YRGVNADAHQVFLMPTAQAAIALVARVLLDPGDLAWVESPGYGGARAAFEAAGATVQGIA
HCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCCEEEEEE
LDQSGMAFETSTDTPRLIFVTPAHQHPTGLLMPPARRQALLRFAARVGARIIEDDYDSEF
ECCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCE
HYEGRPVAALQGADDADSVFYVGTFSKSLHADIRVGYVVVPGHFVDVFAKAQRHTGQIVG
EECCCCEEEECCCCCCCCEEEEEECCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCEEH
ATLQDALAEFIDDGHYAAHIRKTTRLYHARRDYLCDALKAVGSELTVSPPDGGMQVVARL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHH
GPLRDDREICRRLAEAGVTARPLSPHYCAQTGAQGLFLGFAAWNECEIDAGVRILARVIR
CCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHC
EPEPSK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]