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The map label for this gene is mdcB [H]

Identifier: 237811752

GI number: 237811752

Start: 1427044

End: 1428405

Strand: Direct

Name: mdcB [H]

Synonym: GBP346_A1490

Alternate gene names: 237811752

Gene position: 1427044-1428405 (Clockwise)

Preceding gene: 237811751

Following gene: 237811753

Centisome position: 34.82

GC content: 74.38

Gene sequence:

>1362_bases
ATGAAGCGACACGCATGCGCGGTGGCGAAGCCGGCCCGGCGCGACGCGATGTGCCGGGATAGGGCGCGGGCGCTTGACGA
CGGAGGCGGGGCGGATACGCTGTTGGATGCGTTGGATGCGTTGGATGCGTTGGATGCGTTGGATGCGTTGGATGCGTTGG
ATGCGTTGGATGCGTCAGGTGTATCGAATGCGTCGAGTTCGATGGGAGCGGGGGACGCATCGAACCGGCCGAACATCGCA
GCGGTGTCGAGCATATGGGCTTCCCAGTATTTCCCCCCGGCCACGCGGAACGCCTCCGACGGGGCTGACGCGCGAGATAG
CCGGGGGCGCCGTCGACATCCGACGTTCGCCGCGCATCGGCTAGCCTCGCTGACCGCGACCGCGACCGCGACCGCGACCG
CGACCGCGACCGCGACCGCGACCGCGACCGCGACCGCAGCCGCAGCCGCAGCCGCAACGCCGGCATCCATCCCCACGCCG
ACGCCAAGGCCAACATCAACATCAACGCCCACGCCAACAGCAACGGCGATCGCGGCCAACGCGGTACGCTGCCTGCGCGT
CGAGATCGACACGTGGCCGAAGCCCGGACTCGTGAGCCACGTCGACGCGGGCAGCCACGACGACATGACGGCCGACACCT
TCTATCGCAGCGCGGCGGCGCTTGCGCCGTTCTTCGCCGAGCTCGCCGATGCCGGCGCGCGCGACGCCGGCATGCCGGCG
CTGCGCAAGATCGGCCTGCGCGCGGAACGCGCGATGCTGGCCGCGACGGGCGGCGTGAACACGCATCGCGGCGCGATTTT
CGGGCTCGGGCTGCTGTGCGCGGCGGCGGGCCTGCGCGGATCGCGCGAACGGCGCGCGCAACGGGGGCAAGCCGCGGGCG
CGACGCTCGGCGATCTCGTCGCCGCGCGCTGGGGCGACGAGATCGCCGGCGGTCCGCGCGCGGCCGACAGTCATGGCGCG
CGCGCCGCGCGCCGCTACGGCGCGGGCGGCGCGCGCGCGGAGGCGGCGGGCGGTTTCGCGCGCGTCTACGCGGTCGGCGT
GCCGGCGCTGCGCGACGGCGCGCGGCGCGCGCGGGGCGACGCCGAGGCCGCGCGCGTGCACGCGTGTTTCGCGCTGATCG
CCGCGCTCGACGACGACACGAATCTGCTGCATCGCGGCGGCCGCGACGGCCTCGACTTCGCGCAACGAACCGCGCGCGAA
TTTCTCGCGGCGGGCGGCGTGGGCGCGTGCGACTGGCGCGCGCGCGCGGCCGCCGCGCATCGCGCGTTCGTCGCCCGCCG
GCTGAGCCCGGGCGGCGCGGCGGACCTGCTCGCGATGAGCCTCTTCGTCGCCGCGCTCGACGACGCGCGGGCATTGCCGT
GA

Upstream 100 bases:

>100_bases
TGAACTGGCGCGAACTGCATGCGGGCGGGCGAGCAGTCGCGATGAAAACCGCGACGGGCGTCGAACTGGTCGCTCCGCGG
ACGTTTCTGGAGGCGTGGCG

Downstream 100 bases:

>100_bases
CGATCGCGATTCTCTGTTCGGGGCAGGGCGGCCAGCATGCCGGCATGTTCGCGCTGACGGCCGATTTGCCGGAAGCCGCG
CCGCTTTTCGCGCACGCGGC

Product: triphosphoribosyl-dephospho-CoA synthase

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MKRHACAVAKPARRDAMCRDRARALDDGGGADTLLDALDALDALDALDALDALDALDASGVSNASSSMGAGDASNRPNIA
AVSSIWASQYFPPATRNASDGADARDSRGRRRHPTFAAHRLASLTATATATATATATATATATATAAAAAAATPASIPTP
TPRPTSTSTPTPTATAIAANAVRCLRVEIDTWPKPGLVSHVDAGSHDDMTADTFYRSAAALAPFFAELADAGARDAGMPA
LRKIGLRAERAMLAATGGVNTHRGAIFGLGLLCAAAGLRGSRERRAQRGQAAGATLGDLVAARWGDEIAGGPRAADSHGA
RAARRYGAGGARAEAAGGFARVYAVGVPALRDGARRARGDAEAARVHACFALIAALDDDTNLLHRGGRDGLDFAQRTARE
FLAAGGVGACDWRARAAAAHRAFVARRLSPGGAADLLAMSLFVAALDDARALP

Sequences:

>Translated_453_residues
MKRHACAVAKPARRDAMCRDRARALDDGGGADTLLDALDALDALDALDALDALDALDASGVSNASSSMGAGDASNRPNIA
AVSSIWASQYFPPATRNASDGADARDSRGRRRHPTFAAHRLASLTATATATATATATATATATATAAAAAAATPASIPTP
TPRPTSTSTPTPTATAIAANAVRCLRVEIDTWPKPGLVSHVDAGSHDDMTADTFYRSAAALAPFFAELADAGARDAGMPA
LRKIGLRAERAMLAATGGVNTHRGAIFGLGLLCAAAGLRGSRERRAQRGQAAGATLGDLVAARWGDEIAGGPRAADSHGA
RAARRYGAGGARAEAAGGFARVYAVGVPALRDGARRARGDAEAARVHACFALIAALDDDTNLLHRGGRDGLDFAQRTARE
FLAAGGVGACDWRARAAAAHRAFVARRLSPGGAADLLAMSLFVAALDDARALP
>Mature_453_residues
MKRHACAVAKPARRDAMCRDRARALDDGGGADTLLDALDALDALDALDALDALDALDASGVSNASSSMGAGDASNRPNIA
AVSSIWASQYFPPATRNASDGADARDSRGRRRHPTFAAHRLASLTATATATATATATATATATATAAAAAAATPASIPTP
TPRPTSTSTPTPTATAIAANAVRCLRVEIDTWPKPGLVSHVDAGSHDDMTADTFYRSAAALAPFFAELADAGARDAGMPA
LRKIGLRAERAMLAATGGVNTHRGAIFGLGLLCAAAGLRGSRERRAQRGQAAGATLGDLVAARWGDEIAGGPRAADSHGA
RAARRYGAGGARAEAAGGFARVYAVGVPALRDGARRARGDAEAARVHACFALIAALDDDTNLLHRGGRDGLDFAQRTARE
FLAAGGVGACDWRARAAAAHRAFVARRLSPGGAADLLAMSLFVAALDDARALP

Specific function: Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase [H]

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786830, Length=295, Percent_Identity=34.5762711864407, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736
- InterPro:   IPR017555 [H]

Pfam domain/function: PF01874 CitG [H]

EC number: =2.7.8.25 [H]

Molecular weight: Translated: 46010; Mature: 46010

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRHACAVAKPARRDAMCRDRARALDDGGGADTLLDALDALDALDALDALDALDALDASG
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VSNASSSMGAGDASNRPNIAAVSSIWASQYFPPATRNASDGADARDSRGRRRHPTFAAHR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHH
LASLTATATATATATATATATATATAAAAAAATPASIPTPTPRPTSTSTPTPTATAIAAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AVRCLRVEIDTWPKPGLVSHVDAGSHDDMTADTFYRSAAALAPFFAELADAGARDAGMPA
CEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
LRKIGLRAERAMLAATGGVNTHRGAIFGLGLLCAAAGLRGSRERRAQRGQAAGATLGDLV
HHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHH
AARWGDEIAGGPRAADSHGARAARRYGAGGARAEAAGGFARVYAVGVPALRDGARRARGD
HHHCCCHHCCCCCCCCHHHHHHHHHHCCCCCCHHHCCCHHHHHHHCCHHHHHHHHHHCCC
AEAARVHACFALIAALDDDTNLLHRGGRDGLDFAQRTAREFLAAGGVGACDWRARAAAAH
HHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
RAFVARRLSPGGAADLLAMSLFVAALDDARALP
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRHACAVAKPARRDAMCRDRARALDDGGGADTLLDALDALDALDALDALDALDALDASG
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VSNASSSMGAGDASNRPNIAAVSSIWASQYFPPATRNASDGADARDSRGRRRHPTFAAHR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHH
LASLTATATATATATATATATATATAAAAAAATPASIPTPTPRPTSTSTPTPTATAIAAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AVRCLRVEIDTWPKPGLVSHVDAGSHDDMTADTFYRSAAALAPFFAELADAGARDAGMPA
CEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
LRKIGLRAERAMLAATGGVNTHRGAIFGLGLLCAAAGLRGSRERRAQRGQAAGATLGDLV
HHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHH
AARWGDEIAGGPRAADSHGARAARRYGAGGARAEAAGGFARVYAVGVPALRDGARRARGD
HHHCCCHHCCCCCCCCHHHHHHHHHHCCCCCCHHHCCCHHHHHHHCCHHHHHHHHHHCCC
AEAARVHACFALIAALDDDTNLLHRGGRDGLDFAQRTAREFLAAGGVGACDWRARAAAAH
HHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
RAFVARRLSPGGAADLLAMSLFVAALDDARALP
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10561613 [H]