| Definition | Burkholderia pseudomallei MSHR346 chromosome I, complete genome. |
|---|---|
| Accession | NC_012695 |
| Length | 4,098,576 |
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The map label for this gene is sir1 [H]
Identifier: 237811727
GI number: 237811727
Start: 1408948
End: 1410849
Strand: Reverse
Name: sir1 [H]
Synonym: GBP346_A1465
Alternate gene names: 237811727
Gene position: 1410849-1408948 (Counterclockwise)
Preceding gene: 237811728
Following gene: 237811726
Centisome position: 34.42
GC content: 70.61
Gene sequence:
>1902_bases TTGGTGATCCTCGCGCCGCCGATGCGGCGCCTCGCAACCGACACGCGCGACCGCGCGCGTGCCGCCCCACCGCATTGCCC GGCCATGTACCGATACACCGAATTCGACAAGGCGTTCGTGCGCAACCGCGCCGCCCAGTTTCGCGACCAGCTCGAACGCT GGCGGCAAGGCGCGCTGAGCGAGGACGCATTCCGCCCGCTGCGGCTGCAGAACGGCTGGTATGTGCAGCGCCATGCGCCG ATGCTGCGCGTCGCGGTGCCGTACGGCGAGCTGTCGAGCGCGCAGATCCGCATGCTCGCGCGCATCGCGCGCGACTATGA CGTGCCGGAGCCGGCGCGCTACCGCGCCGCGTGCGACGCGCAGGCGCGGCTCGGCACCGTGCGCCTGCCGACGCGCAACG CGCATTTCACGACGCGCACGAACGTGCAGTTCAACTGGATCCCGCTCGAGAAGGCGGCCGACGTGATGGACCTGCTCGCG ACCGTCGACATGCACGGCATCCAGACGAGCGGCAACTGCATCCGCAACATCTCGTGCGACGAGCGCGCGGGCGTCGCGCC CGACGAAATCGCCGATCCGCGGCCGTTCGCCGAAGTGATGCGCCAATGGACGACGCTGCATCCCGAATTCGCGTTCCTGC CGCGCAAGTTCAAGATCGCGATCACGGGCGCGGCCGACGATCGCGCGGCGACCGACTGGCACGATGTCGGCTTAAGGCTC GTGCGCGACGCGGCGGGCGAACTCGGCTTTCGCGTGAGCGTCGGCGGCGGCATGGGGCGCACGCCGATGACGGCCACGCT CGTGCGCGCATTCGTGCCGTGGCGGCACGTGATGAACTACATCGAGGCGATCGTGCGCGTGTACAACCGCTACGGCCGCC GCGACAACAGGTACAAGGCGCGCATCAAGATCCTCGTGAAGGCCGAGGGCCAGCGCTACATCGACGACGTCGACGAGGAA TTCCGGCAAATCGTCGAGCACGACGGCGGCCCGCATACGATCGAGCAGGCGGAGTTCGACCGCGTATGCGCGTCGTTCGT GCCGCCCGTGCCGCCGCCGTGCGCGGCCGGGCGCCACGCAAAGACCGATATCGACGCCGACATGGACGCGGCGCTCGCGC GCATGCGCACGCTCGCCGGCGCACAGCCCGCGTTCGCGCGCTGGCTCGAGCGCAACGTCGCGCCGCACCGGGATCCCGCG CGGCGGATCGTCACGCTGTCGTTCAAGCGCAGGCATCAGGCGCCCGGCGATGCGTCGCCCGAGCAGCTCGACGCGCTCGC GCACCTCGCCGAGCGCTTTTCCGCCGGCGAGGCGCGCGTCACGCACGCGCAGAACGTCGTGCTGCCGTGGGTGCGCGCGA TCGATCTGCACGCGCTGTGGGAGGCCGCGCGCGACGCGGGCCTCGCGAGCGCGAACGTGCGGCTGTTGACCGACATGATC GCGTGCCCCGGCGGCGATTTCTGCGCGCTCGCGAACGCGCGCTCGATCCCGATCGCCGATGCGATCGCCGAACGCTTCGA CGATCTCGACGAGTTGCACGACATCGGCGACGTCGACCTGCACGTGAGCGGCTGCATCAACTCGTGCGGCCATCATCACA GCGGCCACATCGGCATCCTCGGCGTCGACAAGGACGGCGACGAGTGGTACCAGGTGACGCTCGGCGGCTCCGACGGCACG GCCGCGAACGGCCCCGCGCAGCCGGGCAAGGTGATCGGGCCGTCGTTCTCGGCCGACGAGATCGTCGACGTCGTCGACGC GCTCGTCGCCACCTATCTGCGCGTGCGGCGAACCGAGGCCGGGCGCGTCGAACGCTTCATCGACGCGTACCGCCGCGTCG GCCCCGAGCCCTTCAAGGCCGCCGCGAACGCGGCGCGCCATCCCGAGACGAGTGTCGCATGA
Upstream 100 bases:
>100_bases TTCGACCTCGGGCGCGACCGGCCTACGCGCGCCCGCCGCATCTGCTGCGCAAAATCCGTCCGAATCTGCTGCTTGTCGCG CGCGGCCGCGCGCCCTACGC
Downstream 100 bases:
>100_bases GCCCGCCGAACCGCATCCGCCTGCTGAGCGCGAGCGCCCACGGCGACGAGACGCGCGCCGCGCCCGCCCGCGACGGCGCG CCGCTCGCCATCGCGAACGA
Product: nitrite and sulphite reductase 4Fe-4S domain protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 633; Mature: 633
Protein sequence:
>633_residues MVILAPPMRRLATDTRDRARAAPPHCPAMYRYTEFDKAFVRNRAAQFRDQLERWRQGALSEDAFRPLRLQNGWYVQRHAP MLRVAVPYGELSSAQIRMLARIARDYDVPEPARYRAACDAQARLGTVRLPTRNAHFTTRTNVQFNWIPLEKAADVMDLLA TVDMHGIQTSGNCIRNISCDERAGVAPDEIADPRPFAEVMRQWTTLHPEFAFLPRKFKIAITGAADDRAATDWHDVGLRL VRDAAGELGFRVSVGGGMGRTPMTATLVRAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKARIKILVKAEGQRYIDDVDEE FRQIVEHDGGPHTIEQAEFDRVCASFVPPVPPPCAAGRHAKTDIDADMDAALARMRTLAGAQPAFARWLERNVAPHRDPA RRIVTLSFKRRHQAPGDASPEQLDALAHLAERFSAGEARVTHAQNVVLPWVRAIDLHALWEAARDAGLASANVRLLTDMI ACPGGDFCALANARSIPIADAIAERFDDLDELHDIGDVDLHVSGCINSCGHHHSGHIGILGVDKDGDEWYQVTLGGSDGT AANGPAQPGKVIGPSFSADEIVDVVDALVATYLRVRRTEAGRVERFIDAYRRVGPEPFKAAANAARHPETSVA
Sequences:
>Translated_633_residues MVILAPPMRRLATDTRDRARAAPPHCPAMYRYTEFDKAFVRNRAAQFRDQLERWRQGALSEDAFRPLRLQNGWYVQRHAP MLRVAVPYGELSSAQIRMLARIARDYDVPEPARYRAACDAQARLGTVRLPTRNAHFTTRTNVQFNWIPLEKAADVMDLLA TVDMHGIQTSGNCIRNISCDERAGVAPDEIADPRPFAEVMRQWTTLHPEFAFLPRKFKIAITGAADDRAATDWHDVGLRL VRDAAGELGFRVSVGGGMGRTPMTATLVRAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKARIKILVKAEGQRYIDDVDEE FRQIVEHDGGPHTIEQAEFDRVCASFVPPVPPPCAAGRHAKTDIDADMDAALARMRTLAGAQPAFARWLERNVAPHRDPA RRIVTLSFKRRHQAPGDASPEQLDALAHLAERFSAGEARVTHAQNVVLPWVRAIDLHALWEAARDAGLASANVRLLTDMI ACPGGDFCALANARSIPIADAIAERFDDLDELHDIGDVDLHVSGCINSCGHHHSGHIGILGVDKDGDEWYQVTLGGSDGT AANGPAQPGKVIGPSFSADEIVDVVDALVATYLRVRRTEAGRVERFIDAYRRVGPEPFKAAANAARHPETSVA >Mature_633_residues MVILAPPMRRLATDTRDRARAAPPHCPAMYRYTEFDKAFVRNRAAQFRDQLERWRQGALSEDAFRPLRLQNGWYVQRHAP MLRVAVPYGELSSAQIRMLARIARDYDVPEPARYRAACDAQARLGTVRLPTRNAHFTTRTNVQFNWIPLEKAADVMDLLA TVDMHGIQTSGNCIRNISCDERAGVAPDEIADPRPFAEVMRQWTTLHPEFAFLPRKFKIAITGAADDRAATDWHDVGLRL VRDAAGELGFRVSVGGGMGRTPMTATLVRAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKARIKILVKAEGQRYIDDVDEE FRQIVEHDGGPHTIEQAEFDRVCASFVPPVPPPCAAGRHAKTDIDADMDAALARMRTLAGAQPAFARWLERNVAPHRDPA RRIVTLSFKRRHQAPGDASPEQLDALAHLAERFSAGEARVTHAQNVVLPWVRAIDLHALWEAARDAGLASANVRLLTDMI ACPGGDFCALANARSIPIADAIAERFDDLDELHDIGDVDLHVSGCINSCGHHHSGHIGILGVDKDGDEWYQVTLGGSDGT AANGPAQPGKVIGPSFSADEIVDVVDALVATYLRVRRTEAGRVERFIDAYRRVGPEPFKAAANAARHPETSVA
Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]
COG id: COG0155
COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]
Homologues:
None
Paralogues:
None
Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005117 - InterPro: IPR006067 - InterPro: IPR006066 [H]
Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]
EC number: =1.8.7.1 [H]
Molecular weight: Translated: 70295; Mature: 70295
Theoretical pI: Translated: 7.66; Mature: 7.66
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVILAPPMRRLATDTRDRARAAPPHCPAMYRYTEFDKAFVRNRAAQFRDQLERWRQGALS CEEECCCHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC EDAFRPLRLQNGWYVQRHAPMLRVAVPYGELSSAQIRMLARIARDYDVPEPARYRAACDA CCCCCCEEECCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCH QARLGTVRLPTRNAHFTTRTNVQFNWIPLEKAADVMDLLATVDMHGIQTSGNCIRNISCD HHHCCEEECCCCCCCEEEECCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCC ERAGVAPDEIADPRPFAEVMRQWTTLHPEFAFLPRKFKIAITGAADDRAATDWHDVGLRL CCCCCCCHHCCCCCHHHHHHHHHHHCCCCHHCCCCEEEEEEECCCCCCCCCCHHHHHHHH VRDAAGELGFRVSVGGGMGRTPMTATLVRAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKA HHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE RIKILVKAEGQRYIDDVDEEFRQIVEHDGGPHTIEQAEFDRVCASFVPPVPPPCAAGRHA EEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC KTDIDADMDAALARMRTLAGAQPAFARWLERNVAPHRDPARRIVTLSFKRRHQAPGDASP CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHEEEEEHHHHCCCCCCCCH EQLDALAHLAERFSAGEARVTHAQNVVLPWVRAIDLHALWEAARDAGLASANVRLLTDMI HHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH ACPGGDFCALANARSIPIADAIAERFDDLDELHDIGDVDLHVSGCINSCGHHHSGHIGIL HCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCCEEEE GVDKDGDEWYQVTLGGSDGTAANGPAQPGKVIGPSFSADEIVDVVDALVATYLRVRRTEA EECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCH GRVERFIDAYRRVGPEPFKAAANAARHPETSVA HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC >Mature Secondary Structure MVILAPPMRRLATDTRDRARAAPPHCPAMYRYTEFDKAFVRNRAAQFRDQLERWRQGALS CEEECCCHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC EDAFRPLRLQNGWYVQRHAPMLRVAVPYGELSSAQIRMLARIARDYDVPEPARYRAACDA CCCCCCEEECCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCH QARLGTVRLPTRNAHFTTRTNVQFNWIPLEKAADVMDLLATVDMHGIQTSGNCIRNISCD HHHCCEEECCCCCCCEEEECCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCC ERAGVAPDEIADPRPFAEVMRQWTTLHPEFAFLPRKFKIAITGAADDRAATDWHDVGLRL CCCCCCCHHCCCCCHHHHHHHHHHHCCCCHHCCCCEEEEEEECCCCCCCCCCHHHHHHHH VRDAAGELGFRVSVGGGMGRTPMTATLVRAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKA HHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE RIKILVKAEGQRYIDDVDEEFRQIVEHDGGPHTIEQAEFDRVCASFVPPVPPPCAAGRHA EEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC KTDIDADMDAALARMRTLAGAQPAFARWLERNVAPHRDPARRIVTLSFKRRHQAPGDASP CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHEEEEEHHHHCCCCCCCCH EQLDALAHLAERFSAGEARVTHAQNVVLPWVRAIDLHALWEAARDAGLASANVRLLTDMI HHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH ACPGGDFCALANARSIPIADAIAERFDDLDELHDIGDVDLHVSGCINSCGHHHSGHIGIL HCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCCEEEE GVDKDGDEWYQVTLGGSDGTAANGPAQPGKVIGPSFSADEIVDVVDALVATYLRVRRTEA EECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCH GRVERFIDAYRRVGPEPFKAAANAARHPETSVA HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA