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The map label for this gene is yhcK [H]

Identifier: 237811708

GI number: 237811708

Start: 1393096

End: 1394496

Strand: Reverse

Name: yhcK [H]

Synonym: GBP346_A1446

Alternate gene names: 237811708

Gene position: 1394496-1393096 (Counterclockwise)

Preceding gene: 237811710

Following gene: 237811706

Centisome position: 34.02

GC content: 66.02

Gene sequence:

>1401_bases
GTGAGCACCGTCTTCACAGCCCATGAATCGCCGCGTGTGATCGGCACGATCGCCCGGCTCTACACCGCATGCCTGCTGAT
CGGCTTCGCGCTCGTGCCGGCGTTCCTGATCGCCTACGTGCGGTTCTTCATCGATCCGCGGCTCGTCTTCGAGAACCATC
AGTTCCACGAACTGGCAATCGCCGCCGCGACGCTCGAGGGGCTGTTCGTCACCTACGTCACATGGCGCTGCTATCTGGCG
TCGGGCGAGCCGCTGCTGCGCTGGCTCACGCTCGGCTTCCTCGGCTTCGCGCTGATCTATTCGCTGCACGGCGCGTTCAC
CGGCATGGCGCACCGGAACATCTGGCTGTTCCTGCTGTACGGGCCCGCATCGCGCCTCGTGATGTCGATCCTGCTGCTCG
TCGGGCAACTGTCGTACTTCCGCGACGCCGATCCACCGGAGCGCCGCACGCATCTGTCGATGTGGCTGCCGTGGATCGCC
GGCTACGTCGTCGTGTGCTTCGCCGTGGCCGCGATCGCGTATTCGCCGATCGCCGGCCATCTGTGGACGCGCGCATCGAT
GGAGGGCGGCGCGATGATCGTGTCGCTCGTCAACGTCGCGCTGCTGCTCGTGCGGCGCATCCGCACGCCGCTGATGCTCG
TCTACGGCATCTCGGTGACGTCGTTCGCGCTGTCGTCGATCGCGTTCATTCTCGGCAAGCCGTGGAATCACATGTGGTGG
CTCGCGCACGCGGTCTTCGCGGGCGGCTTCTTCATGCTGAGCTTCGGCGTCGTGCAGGCGCTGATGACGACCCGCTCGTT
CGCGACCGTCTACAGCCAGCAGGACTTGATGGCGCGGCTCGCCGAATCGATGGCGCGCACCGAGGGCGTGCTGCAGGAGC
TCAAGCGCACCAATCAGAAGCTCGAGCACCTCGCGACCACCGATCCGCTGACGGGCGCGTCGAACCGGCGCAAGTTCATC
GAGCAGATGCAATCGGAGATCGCGCGCGCGAAACGCGACGGCACCGCGTTCTCGCTGCTCGCGCTCGATCTCGACAACTT
CAAGACGATCAACGACAACTACGGCCATCAGGTCGGCGACGTCGTGCTGCGCAATTTCGTGCGCCAGTGCCTCGCCGCGA
TTCGCCCTTACGACCACATCGCGCGCGTCGGCGGCGAGGAATTCATGGTGCTGCTGCCGCGCATGCTCGCCGACACGGCG
AGCGGCATCGCCGAGCGGGTGCGGACCACGATCGCGAACGCATCGTTCGGCATCGACGGCAAGCACACGCCCGTGACCGT
GAGCATCGGCGTGTCGCAGTACGGGCGCGACGGCGACACCGTCGACGAAATCCTGAGCGCCGCCGACAAGCTGCTCTATC
GCGCGAAGAACGAGGGGCGCAATCGCGTCGTCGCGTCGTAG

Upstream 100 bases:

>100_bases
GAAACGATGCGGCGCGGGACCCGGCGCGACGGCCGCTCGCCGCCCGGCGTCCCGCGCGGATTTCCCACTTCGATCCAGGA
ACAGCGTTGCGGAGGCCACC

Downstream 100 bases:

>100_bases
ACCCTCGTCAGCCGCGGGACAGCGGAGCGGGCGGGACGGCCCGATCGGCGGCGATCCGGCGCGCGCCACCGGGATCGCAA
GCCACGGCGCGGCGATTCGC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSTVFTAHESPRVIGTIARLYTACLLIGFALVPAFLIAYVRFFIDPRLVFENHQFHELAIAAATLEGLFVTYVTWRCYLA
SGEPLLRWLTLGFLGFALIYSLHGAFTGMAHRNIWLFLLYGPASRLVMSILLLVGQLSYFRDADPPERRTHLSMWLPWIA
GYVVVCFAVAAIAYSPIAGHLWTRASMEGGAMIVSLVNVALLLVRRIRTPLMLVYGISVTSFALSSIAFILGKPWNHMWW
LAHAVFAGGFFMLSFGVVQALMTTRSFATVYSQQDLMARLAESMARTEGVLQELKRTNQKLEHLATTDPLTGASNRRKFI
EQMQSEIARAKRDGTAFSLLALDLDNFKTINDNYGHQVGDVVLRNFVRQCLAAIRPYDHIARVGGEEFMVLLPRMLADTA
SGIAERVRTTIANASFGIDGKHTPVTVSIGVSQYGRDGDTVDEILSAADKLLYRAKNEGRNRVVAS

Sequences:

>Translated_466_residues
MSTVFTAHESPRVIGTIARLYTACLLIGFALVPAFLIAYVRFFIDPRLVFENHQFHELAIAAATLEGLFVTYVTWRCYLA
SGEPLLRWLTLGFLGFALIYSLHGAFTGMAHRNIWLFLLYGPASRLVMSILLLVGQLSYFRDADPPERRTHLSMWLPWIA
GYVVVCFAVAAIAYSPIAGHLWTRASMEGGAMIVSLVNVALLLVRRIRTPLMLVYGISVTSFALSSIAFILGKPWNHMWW
LAHAVFAGGFFMLSFGVVQALMTTRSFATVYSQQDLMARLAESMARTEGVLQELKRTNQKLEHLATTDPLTGASNRRKFI
EQMQSEIARAKRDGTAFSLLALDLDNFKTINDNYGHQVGDVVLRNFVRQCLAAIRPYDHIARVGGEEFMVLLPRMLADTA
SGIAERVRTTIANASFGIDGKHTPVTVSIGVSQYGRDGDTVDEILSAADKLLYRAKNEGRNRVVAS
>Mature_465_residues
STVFTAHESPRVIGTIARLYTACLLIGFALVPAFLIAYVRFFIDPRLVFENHQFHELAIAAATLEGLFVTYVTWRCYLAS
GEPLLRWLTLGFLGFALIYSLHGAFTGMAHRNIWLFLLYGPASRLVMSILLLVGQLSYFRDADPPERRTHLSMWLPWIAG
YVVVCFAVAAIAYSPIAGHLWTRASMEGGAMIVSLVNVALLLVRRIRTPLMLVYGISVTSFALSSIAFILGKPWNHMWWL
AHAVFAGGFFMLSFGVVQALMTTRSFATVYSQQDLMARLAESMARTEGVLQELKRTNQKLEHLATTDPLTGASNRRKFIE
QMQSEIARAKRDGTAFSLLALDLDNFKTINDNYGHQVGDVVLRNFVRQCLAAIRPYDHIARVGGEEFMVLLPRMLADTAS
GIAERVRTTIANASFGIDGKHTPVTVSIGVSQYGRDGDTVDEILSAADKLLYRAKNEGRNRVVAS

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=182, Percent_Identity=44.5054945054945, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787262, Length=169, Percent_Identity=38.4615384615385, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=35.1851851851852, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788381, Length=177, Percent_Identity=32.7683615819209, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI87082007, Length=161, Percent_Identity=38.5093167701863, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1786584, Length=170, Percent_Identity=32.3529411764706, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1788085, Length=179, Percent_Identity=33.5195530726257, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787802, Length=162, Percent_Identity=35.1851851851852, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787816, Length=160, Percent_Identity=31.875, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787541, Length=172, Percent_Identity=31.9767441860465, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081974, Length=170, Percent_Identity=26.4705882352941, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081977, Length=182, Percent_Identity=30.2197802197802, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788956, Length=173, Percent_Identity=32.3699421965318, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 51808; Mature: 51677

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVFTAHESPRVIGTIARLYTACLLIGFALVPAFLIAYVRFFIDPRLVFENHQFHELAI
CCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCHHHHHH
AAATLEGLFVTYVTWRCYLASGEPLLRWLTLGFLGFALIYSLHGAFTGMAHRNIWLFLLY
HHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
GPASRLVMSILLLVGQLSYFRDADPPERRTHLSMWLPWIAGYVVVCFAVAAIAYSPIAGH
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LWTRASMEGGAMIVSLVNVALLLVRRIRTPLMLVYGISVTSFALSSIAFILGKPWNHMWW
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LAHAVFAGGFFMLSFGVVQALMTTRSFATVYSQQDLMARLAESMARTEGVLQELKRTNQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHLATTDPLTGASNRRKFIEQMQSEIARAKRDGTAFSLLALDLDNFKTINDNYGHQVGD
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEECCCCCCHHHHH
VVLRNFVRQCLAAIRPYDHIARVGGEEFMVLLPRMLADTASGIAERVRTTIANASFGIDG
HHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KHTPVTVSIGVSQYGRDGDTVDEILSAADKLLYRAKNEGRNRVVAS
CCCCEEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
STVFTAHESPRVIGTIARLYTACLLIGFALVPAFLIAYVRFFIDPRLVFENHQFHELAI
CCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCHHHHHH
AAATLEGLFVTYVTWRCYLASGEPLLRWLTLGFLGFALIYSLHGAFTGMAHRNIWLFLLY
HHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
GPASRLVMSILLLVGQLSYFRDADPPERRTHLSMWLPWIAGYVVVCFAVAAIAYSPIAGH
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LWTRASMEGGAMIVSLVNVALLLVRRIRTPLMLVYGISVTSFALSSIAFILGKPWNHMWW
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LAHAVFAGGFFMLSFGVVQALMTTRSFATVYSQQDLMARLAESMARTEGVLQELKRTNQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHLATTDPLTGASNRRKFIEQMQSEIARAKRDGTAFSLLALDLDNFKTINDNYGHQVGD
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEECCCCCCHHHHH
VVLRNFVRQCLAAIRPYDHIARVGGEEFMVLLPRMLADTASGIAERVRTTIANASFGIDG
HHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KHTPVTVSIGVSQYGRDGDTVDEILSAADKLLYRAKNEGRNRVVAS
CCCCEEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]