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The map label for this gene is cph2 [H]

Identifier: 237811642

GI number: 237811642

Start: 1327040

End: 1328875

Strand: Reverse

Name: cph2 [H]

Synonym: GBP346_A1379

Alternate gene names: 237811642

Gene position: 1328875-1327040 (Counterclockwise)

Preceding gene: 237811645

Following gene: 237811641

Centisome position: 32.42

GC content: 69.17

Gene sequence:

>1836_bases
ATGGAAGCCATCAGGAACAAAACGCCCCGCAAGGGCTCCTGGCGCGCCGCACTTCACCAGCTCCGCCGCTTCGCCTGGTC
GGGCGGCGCGCTGATGCCCGCGCGCGCCGGTACGCCGCGCGCCGACGACACAGTTCGAAGCTGGCTGGAGCAAACCGTCG
GCGCGGTCGATTTCCTCGCCCACGTGGACCGGGACCTGCGCTTCCTGTACGTGTCCGATGCCAGCCTGCGCTTCATCGGC
TATCACCGCGACTATCTGCACACGCTGACGCTGCGCGAGCTGATCCCCGAGCAGGATACCGCGACGCTCGACGCCCTGCT
CGCGCGCGCGTCGCAGACGGGCGATGTCGAGAAGGCGACGCTCTGCCTCGTGAAATCGCTGACCTATCCGCTCGACGTCG
AGGTGCGCGCGGTGCGCAGCCGCCACCACGGCGTCGACGGCTTCGCGATCGCCGCGTTCGACGTGTCGTCGTGGCGCGCG
ATCGAGGCCCGGCTCACCTACGAGCTGCACCACGATCCGATGACGGGGCTCGATAACCTGTCGGCGCTCCTGCCCGCGCT
GATGCGCGCGCAGCAGATCGCCGACGAAGGCGGCGGCTGCACGGCGCTGCTGCTGCTCGATCTCGACGATTACCAGCGGA
TCAACCGCGCGCTCGGCTACGACGCGGGCGACGCGCTGCTGCGCGACACCGCGCAGCGGCTGCAACGGCTCGCGACCCGC
GGCGAGCGGCTCGCGCGGGTCGCGAGCGACAAGTTCGCGGTGATGCTGAGCGCGCCCACGCGCGTCGCCGCGCTCGACGC
GGCCGAAGCGCTCGCGCGCCAGCTGCAGACGGCCGTCCAGCGGCCGTACGCGTATGACGGGCAGGCCGTGCACCTGTCGG
CGAGCGTCGGCATCGCGATCTATCCGGACGCGCGCGCGACGTCGAAGCACGCGCAGCACCACAGCCCGCTGCTGCGGCGC
GCGGACCGCGCGCTCGCGCAGGCGAAGGCGGCGGGCGGCAACGCGCTCGCGTTCCACCAGCCGACCGACGATCCGGCCGA
CGCCGAGCGCCTGAAGCTCGAGGCCGATCTCTACAACGGCGTGCGCAACGGCGAGTTCTCGCTGCATTTCCAGCCGATCA
CGAAGAGCCTGTCGGGCGCCGTGGTCGGCGTCGAGGCGCTGATCCGCTGGCACCATCCGGTGCACGGGCTCGTCGCGCCC
GCGACGTTCATCCCGCTCGCCGAATCGATCGGCCTCATCAACTATCTCGGCAACTGGGTGCTGAAGGCCGCGTGCATGCA
GCTCGTGTCGTGGGACCGGCAAGGCATCGCGCTGCAGTACGTGGCCGTCAACGTGTCGCCGCAGCAGTTCCGCGATCCGC
GTTTCACGCAGAGCGTGCGCGACGCGATCAAGCTGACGGGCATCGATCCGCGCCGCATCGTTCTCGAGATCACCGAAAGC
CTGCTGATGCACGATCCGAATCATGCGAAGACGCTGCTCGAGGAAGTGACCGAGCTCGGCATCCGGTTCGCGGTCGACGA
TTTCGGCACCGGCTACTCGAGCCTCGCGTACCTGCAGAGCTTCCCGCTCGCGAAGCTGAAGATCGACCGCAGTTTCGTCG
AAAATCTGTTGACGTCCAGAAACGACCGCGCGATCGTGTCGGCGGTCGTCGGCCTCGCGCAGACGCTCGAGCTCGAGCTC
GTCGCGGAGGGCGTCGAGACCGAGGCGCAGCGCACGCTGCTCACCGAGATGGGCTGCAACCACATTCAAGGCTGGCTCGT
CTGCCAGGCGCTGCCGTCCGACGAACTCGCGCAACGCTTCGAGGCGCAGGAGCTCCATCTGCACGCCACCGCATGA

Upstream 100 bases:

>100_bases
AATGCTCTAGTTCCTTTCTTCCCTGACGCTAAAGAATCGGCGCGATGCGCCGTTATTGCGTCCGGACACCGGTTCCAGCC
CCTTCACGCCAGCGAGATAC

Downstream 100 bases:

>100_bases
CGCACGCCGCCGGCTTTCTCAATCACTGATCCGTATGCCTATCACCGCACAACTGCCGCGAACGGCGCTGCTCGACAAGC
TCTGGGCCCGGATGAACGAG

Product: sensory box diguanylate cyclase/cyclic diguanylate phosphodiesterase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MEAIRNKTPRKGSWRAALHQLRRFAWSGGALMPARAGTPRADDTVRSWLEQTVGAVDFLAHVDRDLRFLYVSDASLRFIG
YHRDYLHTLTLRELIPEQDTATLDALLARASQTGDVEKATLCLVKSLTYPLDVEVRAVRSRHHGVDGFAIAAFDVSSWRA
IEARLTYELHHDPMTGLDNLSALLPALMRAQQIADEGGGCTALLLLDLDDYQRINRALGYDAGDALLRDTAQRLQRLATR
GERLARVASDKFAVMLSAPTRVAALDAAEALARQLQTAVQRPYAYDGQAVHLSASVGIAIYPDARATSKHAQHHSPLLRR
ADRALAQAKAAGGNALAFHQPTDDPADAERLKLEADLYNGVRNGEFSLHFQPITKSLSGAVVGVEALIRWHHPVHGLVAP
ATFIPLAESIGLINYLGNWVLKAACMQLVSWDRQGIALQYVAVNVSPQQFRDPRFTQSVRDAIKLTGIDPRRIVLEITES
LLMHDPNHAKTLLEEVTELGIRFAVDDFGTGYSSLAYLQSFPLAKLKIDRSFVENLLTSRNDRAIVSAVVGLAQTLELEL
VAEGVETEAQRTLLTEMGCNHIQGWLVCQALPSDELAQRFEAQELHLHATA

Sequences:

>Translated_611_residues
MEAIRNKTPRKGSWRAALHQLRRFAWSGGALMPARAGTPRADDTVRSWLEQTVGAVDFLAHVDRDLRFLYVSDASLRFIG
YHRDYLHTLTLRELIPEQDTATLDALLARASQTGDVEKATLCLVKSLTYPLDVEVRAVRSRHHGVDGFAIAAFDVSSWRA
IEARLTYELHHDPMTGLDNLSALLPALMRAQQIADEGGGCTALLLLDLDDYQRINRALGYDAGDALLRDTAQRLQRLATR
GERLARVASDKFAVMLSAPTRVAALDAAEALARQLQTAVQRPYAYDGQAVHLSASVGIAIYPDARATSKHAQHHSPLLRR
ADRALAQAKAAGGNALAFHQPTDDPADAERLKLEADLYNGVRNGEFSLHFQPITKSLSGAVVGVEALIRWHHPVHGLVAP
ATFIPLAESIGLINYLGNWVLKAACMQLVSWDRQGIALQYVAVNVSPQQFRDPRFTQSVRDAIKLTGIDPRRIVLEITES
LLMHDPNHAKTLLEEVTELGIRFAVDDFGTGYSSLAYLQSFPLAKLKIDRSFVENLLTSRNDRAIVSAVVGLAQTLELEL
VAEGVETEAQRTLLTEMGCNHIQGWLVCQALPSDELAQRFEAQELHLHATA
>Mature_611_residues
MEAIRNKTPRKGSWRAALHQLRRFAWSGGALMPARAGTPRADDTVRSWLEQTVGAVDFLAHVDRDLRFLYVSDASLRFIG
YHRDYLHTLTLRELIPEQDTATLDALLARASQTGDVEKATLCLVKSLTYPLDVEVRAVRSRHHGVDGFAIAAFDVSSWRA
IEARLTYELHHDPMTGLDNLSALLPALMRAQQIADEGGGCTALLLLDLDDYQRINRALGYDAGDALLRDTAQRLQRLATR
GERLARVASDKFAVMLSAPTRVAALDAAEALARQLQTAVQRPYAYDGQAVHLSASVGIAIYPDARATSKHAQHHSPLLRR
ADRALAQAKAAGGNALAFHQPTDDPADAERLKLEADLYNGVRNGEFSLHFQPITKSLSGAVVGVEALIRWHHPVHGLVAP
ATFIPLAESIGLINYLGNWVLKAACMQLVSWDRQGIALQYVAVNVSPQQFRDPRFTQSVRDAIKLTGIDPRRIVLEITES
LLMHDPNHAKTLLEEVTELGIRFAVDDFGTGYSSLAYLQSFPLAKLKIDRSFVENLLTSRNDRAIVSAVVGLAQTLELEL
VAEGVETEAQRTLLTEMGCNHIQGWLVCQALPSDELAQRFEAQELHLHATA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081921, Length=428, Percent_Identity=33.6448598130841, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1787541, Length=440, Percent_Identity=32.7272727272727, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI226510982, Length=432, Percent_Identity=30.5555555555556, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI87081743, Length=249, Percent_Identity=34.9397590361446, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786507, Length=236, Percent_Identity=34.3220338983051, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1790496, Length=237, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1788502, Length=249, Percent_Identity=30.9236947791165, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI1787055, Length=232, Percent_Identity=31.4655172413793, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI87081980, Length=250, Percent_Identity=31.6, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788849, Length=244, Percent_Identity=30.7377049180328, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI87081845, Length=248, Percent_Identity=31.4516129032258, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI87082096, Length=433, Percent_Identity=24.0184757505774, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787410, Length=258, Percent_Identity=23.6434108527132, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788381, Length=211, Percent_Identity=25.5924170616114, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081881, Length=185, Percent_Identity=28.1081081081081, Blast_Score=63, Evalue=7e-11,
Organism=Escherichia coli, GI1789650, Length=441, Percent_Identity=21.0884353741497, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 67353; Mature: 67353

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAIRNKTPRKGSWRAALHQLRRFAWSGGALMPARAGTPRADDTVRSWLEQTVGAVDFLA
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
HVDRDLRFLYVSDASLRFIGYHRDYLHTLTLRELIPEQDTATLDALLARASQTGDVEKAT
HCCCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHH
LCLVKSLTYPLDVEVRAVRSRHHGVDGFAIAAFDVSSWRAIEARLTYELHHDPMTGLDNL
HHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEEEEECCCCCCCHHHH
SALLPALMRAQQIADEGGGCTALLLLDLDDYQRINRALGYDAGDALLRDTAQRLQRLATR
HHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GERLARVASDKFAVMLSAPTRVAALDAAEALARQLQTAVQRPYAYDGQAVHLSASVGIAI
HHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEE
YPDARATSKHAQHHSPLLRRADRALAQAKAAGGNALAFHQPTDDPADAERLKLEADLYNG
CCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHEEEHHHHHCC
VRNGEFSLHFQPITKSLSGAVVGVEALIRWHHPVHGLVAPATFIPLAESIGLINYLGNWV
CCCCEEEEEEEHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LKAACMQLVSWDRQGIALQYVAVNVSPQQFRDPRFTQSVRDAIKLTGIDPRRIVLEITES
HHHHHHHHHHCCCCCEEEEEEEEECCHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
LLMHDPNHAKTLLEEVTELGIRFAVDDFGTGYSSLAYLQSFPLAKLKIDRSFVENLLTSR
HHHCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCHHEEECHHHHHHHHHCC
NDRAIVSAVVGLAQTLELELVAEGVETEAQRTLLTEMGCNHIQGWLVCQALPSDELAQRF
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHCCEEEEECCCCHHHHHHH
EAQELHLHATA
CHHHEEEEECC
>Mature Secondary Structure
MEAIRNKTPRKGSWRAALHQLRRFAWSGGALMPARAGTPRADDTVRSWLEQTVGAVDFLA
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
HVDRDLRFLYVSDASLRFIGYHRDYLHTLTLRELIPEQDTATLDALLARASQTGDVEKAT
HCCCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHH
LCLVKSLTYPLDVEVRAVRSRHHGVDGFAIAAFDVSSWRAIEARLTYELHHDPMTGLDNL
HHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEEEEECCCCCCCHHHH
SALLPALMRAQQIADEGGGCTALLLLDLDDYQRINRALGYDAGDALLRDTAQRLQRLATR
HHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GERLARVASDKFAVMLSAPTRVAALDAAEALARQLQTAVQRPYAYDGQAVHLSASVGIAI
HHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEE
YPDARATSKHAQHHSPLLRRADRALAQAKAAGGNALAFHQPTDDPADAERLKLEADLYNG
CCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHEEEHHHHHCC
VRNGEFSLHFQPITKSLSGAVVGVEALIRWHHPVHGLVAPATFIPLAESIGLINYLGNWV
CCCCEEEEEEEHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LKAACMQLVSWDRQGIALQYVAVNVSPQQFRDPRFTQSVRDAIKLTGIDPRRIVLEITES
HHHHHHHHHHCCCCCEEEEEEEEECCHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
LLMHDPNHAKTLLEEVTELGIRFAVDDFGTGYSSLAYLQSFPLAKLKIDRSFVENLLTSR
HHHCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCHHEEECHHHHHHHHHCC
NDRAIVSAVVGLAQTLELELVAEGVETEAQRTLLTEMGCNHIQGWLVCQALPSDELAQRF
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHCCEEEEECCCCHHHHHHH
EAQELHLHATA
CHHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]