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The map label for this gene is aspB [H]

Identifier: 229918734

GI number: 229918734

Start: 2979724

End: 2980911

Strand: Direct

Name: aspB [H]

Synonym: EAT1b_3021

Alternate gene names: 229918734

Gene position: 2979724-2980911 (Clockwise)

Preceding gene: 229918733

Following gene: 229918735

Centisome position: 99.33

GC content: 49.41

Gene sequence:

>1188_bases
ATGGAACATCTATTAGCGAAACGTGTAAAACAACTCACGCCATCGACTACCTTGGCGATCACAGCTAAGGCGAAGGCACT
GAAAGCTTCAGGCAAAGATGTTATTGGTCTCGGCGCGGGTGAACCTGATTTCAACACACCAGAACGAATCATCGATGCTG
CTTGTCAAGCCGCTCGAGATGGAGACACAAAATACACGCCATCTGGCGGGACAGTCGCGTTGAAAGATGCCATCATTGAA
AAGACGAAACGCGATAGTGGATTGTCGTTCGAACGCAACGAGGTGATGGTGGCTTCAGGTGCGAAACATGCCCTTTACGC
TTTGTTCCAAGCTATTCTAGATGAAGGGGACGAAGTGATTGTCCCAGCCCCATACTGGGTCAGTTACCCGGAACAAATCA
AATTGGCGGACGGGGAACCTGTCTTGGTCGACACGAATGAAGAGACATCATTTAAATTGACGCCAACGCAACTCGAGAGT
GCGATCACTGCTCGTACGAAGGCAGTCATCTTAAACAGCCCATCCAATCCGACGGGAATGATTTATACGAAAGAAGAGCT
ACAGGCACTCGCCGATGTCGTTCTTCGCCACAATCTTCTCGTCGTCAGTGATGAGATTTATGAAAAATTGATTTACGGTG
ATGCGTCGTTCGTATCGATTGCGACCCTTCCGAATATGCGTGAACGCACCATCATTATCAATGGTGTCTCGAAATCTCAC
GCGATGACAGGTTGGCGAATCGGATATGCCGTTGGGGACGCAAAAATCATCGGGGCGATGACGAACTTGGCCTCACACTC
GACATCCAACCCGACATCTGTCGCACAAGCGGCTGCGGTAGAGGCGTACAATGGACCACAAGAAGATGTGGAAATGATGC
GTCAATCGTTCGAGGAACGACTTGAAATCGTCTACGACCGTCTCGTCAAAATTCCTGGCATCACGTGTTTGAAGCCGCAA
GGTGCATTTTACTTATATGCCAACGCGAAGGTCGCGGCCACAGAGAGTGGCTATGACACCGTCGATGCTTGGTGTGAAGC
TGTTCTTGAAGAAGCAAATGTGGCACTCGTGCCTGGTTCTGGCTTCGGACAAGACGATTACGTACGATTATCCTATGCAA
CTGAATTAAAACGCGTATTAGAAGCGCTCGATCGAGTAGAAGACTTCGTTACGAAGCGCGCTCGATAA

Upstream 100 bases:

>100_bases
ATGCGTCTTATACGTATTCGTACTATACGCTTCAGACCGGAGAATTTATTCGACGGGTCCAATTGACCGATCAAATGTAA
TGAATTAGAGGGGGATTATG

Downstream 100 bases:

>100_bases
GCGAAAGGATGGAAATGAACATGACAACTATTTCGATTAACCAATTTAAAGACTATGAAGGCCAATCTGTCCGTGTAGGC
GCGTGGATTGCCAACAAACG

Product: aminotransferase class I and II

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MEHLLAKRVKQLTPSTTLAITAKAKALKASGKDVIGLGAGEPDFNTPERIIDAACQAARDGDTKYTPSGGTVALKDAIIE
KTKRDSGLSFERNEVMVASGAKHALYALFQAILDEGDEVIVPAPYWVSYPEQIKLADGEPVLVDTNEETSFKLTPTQLES
AITARTKAVILNSPSNPTGMIYTKEELQALADVVLRHNLLVVSDEIYEKLIYGDASFVSIATLPNMRERTIIINGVSKSH
AMTGWRIGYAVGDAKIIGAMTNLASHSTSNPTSVAQAAAVEAYNGPQEDVEMMRQSFEERLEIVYDRLVKIPGITCLKPQ
GAFYLYANAKVAATESGYDTVDAWCEAVLEEANVALVPGSGFGQDDYVRLSYATELKRVLEALDRVEDFVTKRAR

Sequences:

>Translated_395_residues
MEHLLAKRVKQLTPSTTLAITAKAKALKASGKDVIGLGAGEPDFNTPERIIDAACQAARDGDTKYTPSGGTVALKDAIIE
KTKRDSGLSFERNEVMVASGAKHALYALFQAILDEGDEVIVPAPYWVSYPEQIKLADGEPVLVDTNEETSFKLTPTQLES
AITARTKAVILNSPSNPTGMIYTKEELQALADVVLRHNLLVVSDEIYEKLIYGDASFVSIATLPNMRERTIIINGVSKSH
AMTGWRIGYAVGDAKIIGAMTNLASHSTSNPTSVAQAAAVEAYNGPQEDVEMMRQSFEERLEIVYDRLVKIPGITCLKPQ
GAFYLYANAKVAATESGYDTVDAWCEAVLEEANVALVPGSGFGQDDYVRLSYATELKRVLEALDRVEDFVTKRAR
>Mature_395_residues
MEHLLAKRVKQLTPSTTLAITAKAKALKASGKDVIGLGAGEPDFNTPERIIDAACQAARDGDTKYTPSGGTVALKDAIIE
KTKRDSGLSFERNEVMVASGAKHALYALFQAILDEGDEVIVPAPYWVSYPEQIKLADGEPVLVDTNEETSFKLTPTQLES
AITARTKAVILNSPSNPTGMIYTKEELQALADVVLRHNLLVVSDEIYEKLIYGDASFVSIATLPNMRERTIIINGVSKSH
AMTGWRIGYAVGDAKIIGAMTNLASHSTSNPTSVAQAAAVEAYNGPQEDVEMMRQSFEERLEIVYDRLVKIPGITCLKPQ
GAFYLYANAKVAATESGYDTVDAWCEAVLEEANVALVPGSGFGQDDYVRLSYATELKRVLEALDRVEDFVTKRAR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=343, Percent_Identity=30.0291545189504, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI56713256, Length=343, Percent_Identity=30.0291545189504, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI95147551, Length=396, Percent_Identity=28.2828282828283, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI169881279, Length=396, Percent_Identity=28.2828282828283, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI169881281, Length=391, Percent_Identity=23.7851662404092, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI4507369, Length=388, Percent_Identity=23.7113402061856, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI19263340, Length=383, Percent_Identity=24.5430809399478, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI215599424, Length=383, Percent_Identity=24.5430809399478, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4885351, Length=360, Percent_Identity=25.8333333333333, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI149944424, Length=171, Percent_Identity=29.8245614035088, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI187936925, Length=174, Percent_Identity=32.183908045977, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI14211921, Length=174, Percent_Identity=32.183908045977, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1786816, Length=381, Percent_Identity=27.5590551181102, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1788722, Length=388, Percent_Identity=30.1546391752577, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788627, Length=392, Percent_Identity=28.8265306122449, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787909, Length=352, Percent_Identity=22.4431818181818, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=289, Percent_Identity=30.7958477508651, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71994476, Length=289, Percent_Identity=30.7958477508651, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17567663, Length=376, Percent_Identity=27.9255319148936, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17567369, Length=359, Percent_Identity=27.5766016713092, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71981209, Length=368, Percent_Identity=22.0108695652174, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=314, Percent_Identity=30.8917197452229, Blast_Score=146, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6320317, Length=372, Percent_Identity=24.7311827956989, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6323118, Length=365, Percent_Identity=25.4794520547945, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28573069, Length=291, Percent_Identity=31.9587628865979, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24646114, Length=291, Percent_Identity=31.9587628865979, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI28573067, Length=291, Percent_Identity=31.9587628865979, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI28573065, Length=291, Percent_Identity=31.9587628865979, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI18859735, Length=310, Percent_Identity=25.4838709677419, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45551451, Length=348, Percent_Identity=23.8505747126437, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641770, Length=348, Percent_Identity=23.8505747126437, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641760, Length=348, Percent_Identity=23.8505747126437, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641768, Length=348, Percent_Identity=23.8505747126437, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641766, Length=348, Percent_Identity=23.8505747126437, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641764, Length=348, Percent_Identity=23.8505747126437, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42912; Mature: 42912

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHLLAKRVKQLTPSTTLAITAKAKALKASGKDVIGLGAGEPDFNTPERIIDAACQAARD
CCHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCC
GDTKYTPSGGTVALKDAIIEKTKRDSGLSFERNEVMVASGAKHALYALFQAILDEGDEVI
CCCEECCCCCEEEHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEE
VPAPYWVSYPEQIKLADGEPVLVDTNEETSFKLTPTQLESAITARTKAVILNSPSNPTGM
ECCCHHCCCCCEEEECCCCEEEEECCCCCEEEECHHHHHHHHHHHEEEEEEECCCCCCEE
IYTKEELQALADVVLRHNLLVVSDEIYEKLIYGDASFVSIATLPNMRERTIIINGVSKSH
EEEHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCC
AMTGWRIGYAVGDAKIIGAMTNLASHSTSNPTSVAQAAAVEAYNGPQEDVEMMRQSFEER
CCCCEEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LEIVYDRLVKIPGITCLKPQGAFYLYANAKVAATESGYDTVDAWCEAVLEEANVALVPGS
HHHHHHHHHHCCCCEEECCCCCEEEEECCEEEECCCCCHHHHHHHHHHHHCCCEEEECCC
GFGQDDYVRLSYATELKRVLEALDRVEDFVTKRAR
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEHLLAKRVKQLTPSTTLAITAKAKALKASGKDVIGLGAGEPDFNTPERIIDAACQAARD
CCHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCC
GDTKYTPSGGTVALKDAIIEKTKRDSGLSFERNEVMVASGAKHALYALFQAILDEGDEVI
CCCEECCCCCEEEHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEE
VPAPYWVSYPEQIKLADGEPVLVDTNEETSFKLTPTQLESAITARTKAVILNSPSNPTGM
ECCCHHCCCCCEEEECCCCEEEEECCCCCEEEECHHHHHHHHHHHEEEEEEECCCCCCEE
IYTKEELQALADVVLRHNLLVVSDEIYEKLIYGDASFVSIATLPNMRERTIIINGVSKSH
EEEHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCC
AMTGWRIGYAVGDAKIIGAMTNLASHSTSNPTSVAQAAAVEAYNGPQEDVEMMRQSFEER
CCCCEEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LEIVYDRLVKIPGITCLKPQGAFYLYANAKVAATESGYDTVDAWCEAVLEEANVALVPGS
HHHHHHHHHHCCCCEEECCCCCEEEEECCEEEECCCCCHHHHHHHHHHHHCCCEEEECCC
GFGQDDYVRLSYATELKRVLEALDRVEDFVTKRAR
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]