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The map label for this gene is hepT [H]

Identifier: 229918708

GI number: 229918708

Start: 2956508

End: 2957470

Strand: Direct

Name: hepT [H]

Synonym: EAT1b_2995

Alternate gene names: 229918708

Gene position: 2956508-2957470 (Clockwise)

Preceding gene: 229918707

Following gene: 229918709

Centisome position: 98.55

GC content: 48.6

Gene sequence:

>963_bases
ATGTCTTTGAAGCGACTTTATCGTCATATGAACCGAGAGATTGATCAAATCGATCAATTCTTATCTACTCGAGTCAGGAC
GGACCACCCTGTCATTGAATCGGCATCGCGCCAATTACTCGATGCCGGTGGCAAGCGCATCCGACCCGCCTTCGTCTTAC
TGAGCGCCGGGTTCGGTGAGACGAAAGATATCCGTTTGACGAAAGTTGCCTCAAGTCTTGAGTTGATTCATATGGCATCA
CTCGTGCATGACGATGTCATCGACGACGCGATGCTCCGTCGTGGCAAACCGACCGTGATGGAACGATATGATGAAACAGT
AGCGATGTATACAGGGAATACGTTATTCGGAGAAGCGATTCGTCTCGTATCCGAAATTGATTCACCAGAAGTGATGCGCA
TCATGGCAGATACGATGGAACGAATCTGTGTCGGTGAAATCAATCAAATTCAAGATCAATATGAGTGGGGGCAATCACCG
AAGCGCTATTTAGATCGGATTGCGCGAAAGACCGCTCTGTTGATTGAAACGAGTTGTGCGGCTGGAGCTGTCATCTCTGG
AGCGTCTCCACAAACCGTGAAGCAATTAAGCCTGTTTGGATATGACATCGGCATGGCTTTTCAAATGACGGATGACTTGC
TCGATTTTACCGCTAAGAGTTTTCAACTCGGTAAGCCGGTCGGGGAAGATTTGAAGCACGGTCATAAAACGTTACCGCTC
CTGTATTCATCTGAGGACCCTGACTTTTATGAACGTCTCCGTCAAGTGAACGCCTCGACGGATGCGGAAGTGACGAAATC
TCTCGTCCGGGAAGTGCAACGAAACGGAACGTTAGAACGCAGTCAACGGACGATCGATCGTTACGTCAATCGTGCCATCC
GCCGACTAGACGGGTTGCCGGATGTTCCAGACAAGCGATCGTTAATTGAAATTGCGCAATATATTGGGAAACGCAAATGG
TAA

Upstream 100 bases:

>100_bases
GCTCAAGCGGATGTTCGAAGATGCCGGGTTTGAACAAGTCGAAGTGAAGACATTCTCCGGAGGTGCATGTGCCATGCATC
TAGGAAAGAAGTGGTGAACC

Downstream 100 bases:

>100_bases
ATGCCCATGTAACCCCTTTCAAAAATGTGTCGGACCGTGTACACTAAATACGTACATCGTACACATTTATAGACCTAGGG
GGATTTGGGGAATGGAAAAG

Product: trans-hexaprenyltranstransferase

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSLKRLYRHMNREIDQIDQFLSTRVRTDHPVIESASRQLLDAGGKRIRPAFVLLSAGFGETKDIRLTKVASSLELIHMAS
LVHDDVIDDAMLRRGKPTVMERYDETVAMYTGNTLFGEAIRLVSEIDSPEVMRIMADTMERICVGEINQIQDQYEWGQSP
KRYLDRIARKTALLIETSCAAGAVISGASPQTVKQLSLFGYDIGMAFQMTDDLLDFTAKSFQLGKPVGEDLKHGHKTLPL
LYSSEDPDFYERLRQVNASTDAEVTKSLVREVQRNGTLERSQRTIDRYVNRAIRRLDGLPDVPDKRSLIEIAQYIGKRKW

Sequences:

>Translated_320_residues
MSLKRLYRHMNREIDQIDQFLSTRVRTDHPVIESASRQLLDAGGKRIRPAFVLLSAGFGETKDIRLTKVASSLELIHMAS
LVHDDVIDDAMLRRGKPTVMERYDETVAMYTGNTLFGEAIRLVSEIDSPEVMRIMADTMERICVGEINQIQDQYEWGQSP
KRYLDRIARKTALLIETSCAAGAVISGASPQTVKQLSLFGYDIGMAFQMTDDLLDFTAKSFQLGKPVGEDLKHGHKTLPL
LYSSEDPDFYERLRQVNASTDAEVTKSLVREVQRNGTLERSQRTIDRYVNRAIRRLDGLPDVPDKRSLIEIAQYIGKRKW
>Mature_319_residues
SLKRLYRHMNREIDQIDQFLSTRVRTDHPVIESASRQLLDAGGKRIRPAFVLLSAGFGETKDIRLTKVASSLELIHMASL
VHDDVIDDAMLRRGKPTVMERYDETVAMYTGNTLFGEAIRLVSEIDSPEVMRIMADTMERICVGEINQIQDQYEWGQSPK
RYLDRIARKTALLIETSCAAGAVISGASPQTVKQLSLFGYDIGMAFQMTDDLLDFTAKSFQLGKPVGEDLKHGHKTLPLL
YSSEDPDFYERLRQVNASTDAEVTKSLVREVQRNGTLERSQRTIDRYVNRAIRRLDGLPDVPDKRSLIEIAQYIGKRKW

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=296, Percent_Identity=31.4189189189189, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4758430, Length=283, Percent_Identity=22.2614840989399, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI83700220, Length=283, Percent_Identity=22.2614840989399, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789578, Length=322, Percent_Identity=28.5714285714286, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1786623, Length=245, Percent_Identity=32.2448979591837, Blast_Score=85, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17505681, Length=261, Percent_Identity=33.3333333333333, Blast_Score=144, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6319475, Length=290, Percent_Identity=31.0344827586207, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24651612, Length=302, Percent_Identity=29.4701986754967, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI281365769, Length=249, Percent_Identity=22.0883534136546, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24660002, Length=249, Percent_Identity=22.0883534136546, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 36383; Mature: 36252

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKRLYRHMNREIDQIDQFLSTRVRTDHPVIESASRQLLDAGGKRIRPAFVLLSAGFGE
CCHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHEEEECCCCC
TKDIRLTKVASSLELIHMASLVHDDVIDDAMLRRGKPTVMERYDETVAMYTGNTLFGEAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEECCHHHHHHH
RLVSEIDSPEVMRIMADTMERICVGEINQIQDQYEWGQSPKRYLDRIARKTALLIETSCA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHH
AGAVISGASPQTVKQLSLFGYDIGMAFQMTDDLLDFTAKSFQLGKPVGEDLKHGHKTLPL
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCE
LYSSEDPDFYERLRQVNASTDAEVTKSLVREVQRNGTLERSQRTIDRYVNRAIRRLDGLP
EECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
DVPDKRSLIEIAQYIGKRKW
CCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLKRLYRHMNREIDQIDQFLSTRVRTDHPVIESASRQLLDAGGKRIRPAFVLLSAGFGE
CHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHEEEECCCCC
TKDIRLTKVASSLELIHMASLVHDDVIDDAMLRRGKPTVMERYDETVAMYTGNTLFGEAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEECCHHHHHHH
RLVSEIDSPEVMRIMADTMERICVGEINQIQDQYEWGQSPKRYLDRIARKTALLIETSCA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHH
AGAVISGASPQTVKQLSLFGYDIGMAFQMTDDLLDFTAKSFQLGKPVGEDLKHGHKTLPL
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCE
LYSSEDPDFYERLRQVNASTDAEVTKSLVREVQRNGTLERSQRTIDRYVNRAIRRLDGLP
EECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
DVPDKRSLIEIAQYIGKRKW
CCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]