Click here to switch to the map view.

The map label for this gene is tsf

Identifier: 229918656

GI number: 229918656

Start: 2901074

End: 2901955

Strand: Direct

Name: tsf

Synonym: EAT1b_2943

Alternate gene names: 229918656

Gene position: 2901074-2901955 (Clockwise)

Preceding gene: 229918655

Following gene: 229918657

Centisome position: 96.71

GC content: 46.49

Gene sequence:

>882_bases
ATGGCAGTTACAGCAGCAATGGTAAAAGAACTTCGTGAAAAAACAGGAGCAGGAATGCTCGATTGCAAAAAAGCACTCGT
TGAAACAGACGGTGACATGCAAGCAGCAATCGACTTCCTTCGCGAAAAAGGAATCGCTAAAGCAGCAGCAAAAGGTGATC
GTATCGCCGCTGAAGGTTTGACAGCAGTAGCAGTTGAAGGCAACAAAGCTGTGCTCGTCGAAATCAACTCAGAAACAGAC
TTCGTTGCGAAGAACGAGAAGTTCCAAACACTCGTCAACAACGTAGCAAAAGCAGTACTCGCATCAGGCGCAACAACTGC
AGAAGCGGCACTCGCGGCTGAGTACGAAGCAGGTAAAACACTTGAAACGTACATCCAAGAAGAAGCTTCTACAATCGGAG
AGAAAATCTCACTCCGTCGTGTAGCTGTTCTTGAAAAAGCTGAAGATGCAGTATTCGGTACGTACCTCCACATGGGTGGT
CGCATCGGGTCAGTCGTTGTCATCGACGGCACATCTGACGAGACAGTTGCTAAAGACGTTGCAATGCACGTTGCTGCAGC
TAGCCCACTTTACGCGACACGCGATGAAGTATCAGCTGAAGAAATCGACCGCGAGAAGAAAGTCTTGACTGAGCAAGCAC
TCAACGAAGGCAAGCCTGCTAACATCGTTGAGAAGATGATTGCTGGTCGTATGAACAAGTACTTCGAGGAAATCTGCCTC
GTTGACCAAACGTTCGTAAAAGACAGCGACTTCAAAGTTGGTAAGTACGTAGAATCAAAAGGCGGAAAAATCAACTCGTT
CGTACGCTTCGAAGTAGGAGAAGGTATGGAGAAACGTGAAGAGAACTTTGCTGAAGAAGTTATGAACCAACTTAAAAAAT
AA

Upstream 100 bases:

>100_bases
GATAAAGGGAAAGCCTTTTATCACCTTTTTTTAGGACATGTAATCAAAAAGCCCTGTGCTTTTTCTTAAAATTCGTTAGT
TTTACAAGGAGGAATTTCCG

Downstream 100 bases:

>100_bases
TCTGTGTCACAATCTGTGATACAACTAAAATTGGGAACACGTCTGTATAACCTTGAGTTAGTTCGTTAAGGGAGCGTGTT
CCCTTTTTTCAAGCAAGAGG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MAVTAAMVKELREKTGAGMLDCKKALVETDGDMQAAIDFLREKGIAKAAAKGDRIAAEGLTAVAVEGNKAVLVEINSETD
FVAKNEKFQTLVNNVAKAVLASGATTAEAALAAEYEAGKTLETYIQEEASTIGEKISLRRVAVLEKAEDAVFGTYLHMGG
RIGSVVVIDGTSDETVAKDVAMHVAAASPLYATRDEVSAEEIDREKKVLTEQALNEGKPANIVEKMIAGRMNKYFEEICL
VDQTFVKDSDFKVGKYVESKGGKINSFVRFEVGEGMEKREENFAEEVMNQLKK

Sequences:

>Translated_293_residues
MAVTAAMVKELREKTGAGMLDCKKALVETDGDMQAAIDFLREKGIAKAAAKGDRIAAEGLTAVAVEGNKAVLVEINSETD
FVAKNEKFQTLVNNVAKAVLASGATTAEAALAAEYEAGKTLETYIQEEASTIGEKISLRRVAVLEKAEDAVFGTYLHMGG
RIGSVVVIDGTSDETVAKDVAMHVAAASPLYATRDEVSAEEIDREKKVLTEQALNEGKPANIVEKMIAGRMNKYFEEICL
VDQTFVKDSDFKVGKYVESKGGKINSFVRFEVGEGMEKREENFAEEVMNQLKK
>Mature_292_residues
AVTAAMVKELREKTGAGMLDCKKALVETDGDMQAAIDFLREKGIAKAAAKGDRIAAEGLTAVAVEGNKAVLVEINSETDF
VAKNEKFQTLVNNVAKAVLASGATTAEAALAAEYEAGKTLETYIQEEASTIGEKISLRRVAVLEKAEDAVFGTYLHMGGR
IGSVVVIDGTSDETVAKDVAMHVAAASPLYATRDEVSAEEIDREKKVLTEQALNEGKPANIVEKMIAGRMNKYFEEICLV
DQTFVKDSDFKVGKYVESKGGKINSFVRFEVGEGMEKREENFAEEVMNQLKK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=304, Percent_Identity=27.3026315789474, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI291084500, Length=320, Percent_Identity=27.1875, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI291084498, Length=99, Percent_Identity=44.4444444444444, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI291084502, Length=99, Percent_Identity=44.4444444444444, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786366, Length=285, Percent_Identity=43.1578947368421, Blast_Score=220, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI17561440, Length=294, Percent_Identity=26.8707482993197, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI19921466, Length=303, Percent_Identity=28.0528052805281, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_EXISA (C4L651)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002887302.1
- GeneID:   7871086
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_2943
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31673; Mature: 31542

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTAAMVKELREKTGAGMLDCKKALVETDGDMQAAIDFLREKGIAKAAAKGDRIAAEGL
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCCCHHCCC
TAVAVEGNKAVLVEINSETDFVAKNEKFQTLVNNVAKAVLASGATTAEAALAAEYEAGKT
EEEEEECCEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCH
LETYIQEEASTIGEKISLRRVAVLEKAEDAVFGTYLHMGGRIGSVVVIDGTSDETVAKDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHH
AMHVAAASPLYATRDEVSAEEIDREKKVLTEQALNEGKPANIVEKMIAGRMNKYFEEICL
HHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VDQTFVKDSDFKVGKYVESKGGKINSFVRFEVGEGMEKREENFAEEVMNQLKK
HHHHHHCCCCCCHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVTAAMVKELREKTGAGMLDCKKALVETDGDMQAAIDFLREKGIAKAAAKGDRIAAEGL
CCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCCCHHCCC
TAVAVEGNKAVLVEINSETDFVAKNEKFQTLVNNVAKAVLASGATTAEAALAAEYEAGKT
EEEEEECCEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCH
LETYIQEEASTIGEKISLRRVAVLEKAEDAVFGTYLHMGGRIGSVVVIDGTSDETVAKDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHH
AMHVAAASPLYATRDEVSAEEIDREKKVLTEQALNEGKPANIVEKMIAGRMNKYFEEICL
HHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VDQTFVKDSDFKVGKYVESKGGKINSFVRFEVGEGMEKREENFAEEVMNQLKK
HHHHHHCCCCCCHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA