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The map label for this gene is fabD [H]

Identifier: 229918597

GI number: 229918597

Start: 2850205

End: 2851125

Strand: Direct

Name: fabD [H]

Synonym: EAT1b_2884

Alternate gene names: 229918597

Gene position: 2850205-2851125 (Clockwise)

Preceding gene: 229918596

Following gene: 229918598

Centisome position: 95.01

GC content: 53.96

Gene sequence:

>921_bases
ATGGGGAAAGTAGCATGGGTGTTTCCGGGGCAAGGTTCTCAAGCCGTTGGAATGGGACAAACCTTTTTAGATCACCCTGA
AACGCTTCAAGCAATCGGACGTCGACTCGGGTTTGACCTCCTTGAAGTCATGTCATCCGGGTCGAAGGAAGACCTACAAG
AAACGGAAGTGGCACAGCCGGCCATCGTGGCGCACGCCTCGCTCCTCGCGCAAGCCTATGCGAAGAGCGGTGCGGCACCA
GATGTCGTCATCGGGCATAGTGTCGGTGAATATGCGGCGCTCGTCAGTGCGGGTGTCATCGATCTTGAAGAGGCGACCGT
CCTCGTCCGAGCACGTGGGCAGTTGATGTCTGAAGTGAAGGATGGAACGATGGCGGCAGTCGTCGGGATGACCGATCTTC
AAGAGGCGCTCCATATCACTGAAAAGATCAGTGCGAGCGGGAATTTAGTTCAAATCGCCAACTTGAATTGTCCTGGTCAA
TTCGTGATTTCAGGGCATGTCGACGCGGTCGAACAAGCGGGCGTGGAATTGAAGGCTGCCGGTGCGAAGCGGGTATTGCC
GTTAAATGTATCTGGAGCGTTCCATAGTTCCTACATGATGCCGGCGGCAACGCGTTTCCAAGATGTCCTCGCCTCGTCAC
CGTTTGAAGCGGCTTCCGTCGACTTGATTTCGAACGTGGACGCGGCGGTGCATCGTGACCCTGAACAGTTGAAGGCGTTA
TTGACGAAACAACTGTATTCGTCTGTCCGCTTTGAAGATTGTGTACGCAAGGCGATTGCAGACGGGGTAGACACGTTCAT
CGAGTTCGGTCCATCTTCACCGCTTTCAGGATTGATTAAACGAATCGACTCGAACGTTTCGATTCAAAAGGCGACCACGC
TAGAAGAAGTCGCCTCGTTAGGAGGAGAAGTACGTGCATGA

Upstream 100 bases:

>100_bases
CATGAGTGCGTTGAAACAGGCGAAAATCATGGTAGATCACGATGTCGTGGAAAAAATCAAGCGTGCCAAAGCCATAGACT
AAGCGAAAGCAGGTGAAGAT

Downstream 100 bases:

>100_bases
TCAAGTGGCGATCGTGACTGGGGCGTCCCGGGGAATCGGGGCGGCCATCGCGAAACGTTTAGGGGAAGATGGCTTTCGGG
TCGTCGTGAACTACTCGGGT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MGKVAWVFPGQGSQAVGMGQTFLDHPETLQAIGRRLGFDLLEVMSSGSKEDLQETEVAQPAIVAHASLLAQAYAKSGAAP
DVVIGHSVGEYAALVSAGVIDLEEATVLVRARGQLMSEVKDGTMAAVVGMTDLQEALHITEKISASGNLVQIANLNCPGQ
FVISGHVDAVEQAGVELKAAGAKRVLPLNVSGAFHSSYMMPAATRFQDVLASSPFEAASVDLISNVDAAVHRDPEQLKAL
LTKQLYSSVRFEDCVRKAIADGVDTFIEFGPSSPLSGLIKRIDSNVSIQKATTLEEVASLGGEVRA

Sequences:

>Translated_306_residues
MGKVAWVFPGQGSQAVGMGQTFLDHPETLQAIGRRLGFDLLEVMSSGSKEDLQETEVAQPAIVAHASLLAQAYAKSGAAP
DVVIGHSVGEYAALVSAGVIDLEEATVLVRARGQLMSEVKDGTMAAVVGMTDLQEALHITEKISASGNLVQIANLNCPGQ
FVISGHVDAVEQAGVELKAAGAKRVLPLNVSGAFHSSYMMPAATRFQDVLASSPFEAASVDLISNVDAAVHRDPEQLKAL
LTKQLYSSVRFEDCVRKAIADGVDTFIEFGPSSPLSGLIKRIDSNVSIQKATTLEEVASLGGEVRA
>Mature_305_residues
GKVAWVFPGQGSQAVGMGQTFLDHPETLQAIGRRLGFDLLEVMSSGSKEDLQETEVAQPAIVAHASLLAQAYAKSGAAPD
VVIGHSVGEYAALVSAGVIDLEEATVLVRARGQLMSEVKDGTMAAVVGMTDLQEALHITEKISASGNLVQIANLNCPGQF
VISGHVDAVEQAGVELKAAGAKRVLPLNVSGAFHSSYMMPAATRFQDVLASSPFEAASVDLISNVDAAVHRDPEQLKALL
TKQLYSSVRFEDCVRKAIADGVDTFIEFGPSSPLSGLIKRIDSNVSIQKATTLEEVASLGGEVRA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=318, Percent_Identity=31.7610062893082, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI27477045, Length=111, Percent_Identity=42.3423423423423, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=40.9090909090909, Blast_Score=179, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=30.3754266211604, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17550940, Length=301, Percent_Identity=28.2392026578073, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24665753, Length=302, Percent_Identity=29.4701986754967, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32127; Mature: 31996

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKVAWVFPGQGSQAVGMGQTFLDHPETLQAIGRRLGFDLLEVMSSGSKEDLQETEVAQP
CCCEEEEECCCCCCCCCCCCHHHCCHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHCCH
AIVAHASLLAQAYAKSGAAPDVVIGHSVGEYAALVSAGVIDLEEATVLVRARGQLMSEVK
HHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHC
DGTMAAVVGMTDLQEALHITEKISASGNLVQIANLNCPGQFVISGHVDAVEQAGVELKAA
CCHHEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCHHHHHHCCCEEEEC
GAKRVLPLNVSGAFHSSYMMPAATRFQDVLASSPFEAASVDLISNVDAAVHRDPEQLKAL
CCCEEEEEECCCCHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCHHHHCCCHHHHHHH
LTKQLYSSVRFEDCVRKAIADGVDTFIEFGPSSPLSGLIKRIDSNVSIQKATTLEEVASL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHC
GGEVRA
CCCCCC
>Mature Secondary Structure 
GKVAWVFPGQGSQAVGMGQTFLDHPETLQAIGRRLGFDLLEVMSSGSKEDLQETEVAQP
CCEEEEECCCCCCCCCCCCHHHCCHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHCCH
AIVAHASLLAQAYAKSGAAPDVVIGHSVGEYAALVSAGVIDLEEATVLVRARGQLMSEVK
HHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHC
DGTMAAVVGMTDLQEALHITEKISASGNLVQIANLNCPGQFVISGHVDAVEQAGVELKAA
CCHHEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCHHHHHHCCCEEEEC
GAKRVLPLNVSGAFHSSYMMPAATRFQDVLASSPFEAASVDLISNVDAAVHRDPEQLKAL
CCCEEEEEECCCCHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCHHHHCCCHHHHHHH
LTKQLYSSVRFEDCVRKAIADGVDTFIEFGPSSPLSGLIKRIDSNVSIQKATTLEEVASL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHC
GGEVRA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]